Journal Articles
Review
Biology and function of glypican-3 as a candidate for early cancerous transformation of hepatocytes in hepatocellular carcinoma (Review)
Mauro Montalbano, Jeremias Georgiadis, Ashlyn L. Masterson, Joshua T. McGuire, Janika Prajapati, Ali Shirafkan, Cristiana Rastellini, Luca Cicalese
Pages: 1291-1300 Published online on: 18 January 2017
Review
New insights and future perspectives in the therapeutic strategy of adrenocortical carcinoma (Review)
Antonio Stigliano, Lidia Cerquetti, Pina Lardo, Elisa Petrangeli, Vincenzo Toscano
Pages: 1301-1311 Published online on: 07 February 2017
Review
Diets link metabolic syndrome and colorectal cancer development (Review)
Jirakrit Saetang, Surasak Sangkhathat
Pages: 1312-1320 Published online on: 18 January 2017
Review
Effects of different mycotoxins on humans, cell genome and their involvement in cancer (Review)
Mowaffaq Adam Ahmed Adam, Yasser M. Tabana, Khirun Binti Musa, Doblin Anak Sandai
Pages: 1321-1336 Published online on: 06 February 2017
Review
Radiological biomarkers for assessing response to locoregional therapies in hepatocellular carcinoma: From morphological to functional imaging (Review)
Xiao-Dan Ye, Zuguo Yuan, Jian Zhang, Zheng Yuan
Pages: 1337-1346 Published online on: 03 February 2017
Review
Determining EGFR-TKI sensitivity of G719X and other uncommon EGFR mutations in non-small cell lung cancer: Perplexity and solution (Review)
Kaidi Li, Maojun Yang, Naixin Liang, Shanqing Li
Pages: 1347-1358 Published online on: 30 January 2017
Review
Long non-coding RNAs act as regulators of cell autophagy in diseases (Review)
Zhijie Xu, Yuanliang Yan, Long Qian, Zhicheng Gong
Pages: 1359-1366 Published online on: 01 February 2017
Article
In vitro long-term treatment with MAPK inhibitors induces melanoma cells with resistance plasticity to inhibitors while retaining sensitivity to CD8 T cells
Florencia Paula Madorsky Rowdo, Antonela Barón, Erika María von Euw, José Mordoh
Pages: 1367-1378 Published online on: 13 January 2017
Article
Analysis of chromosomal radiosensitivity of healthy BRCA2 mutation carriers and non-carriers in BRCA families with the G2 micronucleus assay
Annelot Baert, Julie Depuydt, Tom Van Maerken, Bruce Poppe, Fransiska Malfait, Tim Van Damme, Sylvia De Nobele, Gianpaolo Perletti, Kim De Leeneer, Kathleen B.M. Claes, Anne Vral
Pages: 1379-1386 Published online on: 25 January 2017
Article
Targeting ROCK2 rather than ROCK1 inhibits Ewing sarcoma malignancy
Rosa Simona Pinca, Maria Cristina Manara, Valentina Chiadini, Piero Picci, Cinzia Zucchini, Katia Scotlandi
Pages: 1387-1393 Published online on: 20 January 2017
Article
Tanshinone IIA suppresses gastric cancer cell proliferation and migration by downregulation of FOXM1
Jiao Yu, Xiaoxia Wang, Yuhua Li, Bin Tang
Pages: 1394-1400 Published online on: 30 January 2017
Article
Role of miR-647 in human gastric cancer suppression
Wenlong Cao, Weiyuan Wei, Zexu Zhan, Dongyi Xie, Yubo Xie, Qiang Xiao
Pages: 1401-1411 Published online on: 17 January 2017
Article
ELF5 in epithelial ovarian carcinoma tissues and biological behavior in ovarian carcinoma cells
Hongchao Yan, Linglin Qiu, Xiaolei Xie, He Yang, Yongli Liu, Xiaoman Lin, Hongxiang Huang
Pages: 1412-1418 Published online on: 02 February 2017
Article
Inhibiting PLK1 induces autophagy of acute myeloid leukemia cells via mammalian target of rapamycin pathway dephosphorylation
Yan-Fang Tao, Zhi-Heng Li, Wei-Wei Du, Li-Xiao Xu, Jun-Li Ren, Xiao-Lu Li, Fang Fang, Yi Xie, Mei Li, Guang-Hui Qian, Yan-Hong Li, Yi-Ping Li, Gang Li, Yi Wu, Xing Feng, Jian Wang, Wei-Qi He, Shao-Yan Hu, Jun Lu, Jian Pan
Pages: 1419-1429 Published online on: 02 February 2017
Article
Involvement of EZH2 in aerobic glycolysis of prostate cancer through miR-181b/HK2 axis
Tao Tao, Ming Chen, Ranran Jiang, Han Guan, Yeqing Huang, Huan Su, Qiang Hu, Xu Han, Jun Xiao
Pages: 1430-1436 Published online on: 07 February 2017
Article
Upregulation of miR-21 expression is a valuable predicator of advanced clinicopathological features and poor prognosis in patients with renal cell carcinoma through the p53/p21‑cyclin E2‑Bax/caspase-3 signaling pathway
Zhihong Liu, You Lu, Yingmin Xiao, Yipin Lu
Pages: 1437-1444 Published online on: 24 January 2017
Article
miR-922 regulates CYLD expression and promotes the cell proliferation of human hepatocellular carcinoma
Jianping Liu, Zheng Su, Yunjie Zeng, Huayao Zhang, Shanglin Yang, Gaojie Liu
Pages: 1445-1450 Published online on: 07 February 2017
Article
NHE1 is upregulated in gastric cancer and regulates gastric cancer cell proliferation, migration and invasion Corrigendum in /10.3892/or.2019.7055
Rui Xie, Haibo Wang, Hai Jin, Guorong Wen, Biguang Tuo, Jingyu Xu
Pages: 1451-1460 Published online on: 18 January 2017
Article
Exploration of bladder cancer molecular mechanisms based on miRNA-mRNA regulatory network
Wenfeng Li, Jia Liu, Di Zou, Xiaye Cai, Jingying Wang, Jinmeng Wang, Li Zhu, Liang Zhao, Rongying Ou, Yunsheng Xu
Pages: 1461-1468 Published online on: 07 February 2017
Article
miR-181a-5p, an inducer of Wnt-signaling, facilitates cell proliferation in acute lymphoblastic leukemia
Xiaoming Lyu, Jinbang Li, Xi Yun, Rui Huang, Xubin Deng, Yingping Wang, Youming Chen, Gang Xiao
Pages: 1469-1476 Published online on: 06 February 2017
Article
Characterization of the microRNA profile in early-stage cervical squamous cell carcinoma by next-generation sequencing
Wansong Lin, Mei Feng, Guilin Chen, Zhifeng Zhou, Jieyu Li, Yunbin Ye
Pages: 1477-1486 Published online on: 16 January 2017
Article
Downregulation of OCLN and GAS1 in clear cell renal cell carcinoma
André Luis Giacometti Conceição, Camila Tainah Da Silva, Rodolfo Miglioli Badial, Marina Curado Valsechi, Bruna Stuqui, Jéssica Domingues Gonçalves, Miriam Galvonas Jasiulionis, Marilia De Freitas Calmon, Paula Rahal
Pages: 1487-1496 Published online on: 31 January 2017
Article
Ginsenoside‑Rg5 treatment inhibits apoptosis of chondrocytes and degradation of cartilage matrix in a rat model of osteoarthritis
Ping Zhang
Pages: 1497-1502 Published online on: 19 January 2017
Article
Downregulation of leucine‑rich‑α‑2‑glycoprotein 1 expression is associated with the tumorigenesis of head and neck squamous cell carcinoma
Yongping Wang, Chen Chen, Qingquan Hua, Lei Wang, Fen Li, Man Li, Zhidan Mei, Tao Zhou, Bokui Xiao, Zezhang Tao
Pages: 1503-1510 Published online on: 17 January 2017
Article
Overexpression of ARF1 is associated with cell proliferation and migration through PI3K signal pathway in ovarian cancer
Guifang Gu, Yannan Chen, Chengwei Duan, Linsen Zhou, Caiwen Chen, Jie Chen, Jialin Cheng, Nannan Shi, Yunfeng Jin, Qinghua Xi, Jianxin Zhong
Pages: 1511-1520 Published online on: 18 January 2017
Article
Cripto-1 promotes epithelial-mesenchymal transition in prostate cancer via Wnt/β-catenin signaling Corrigendum in /10.3892/or.2024.8734
Yan Liu, Zhenbang Qin, Kuo Yang, Ranlu Liu, Yong Xu
Pages: 1521-1528 Published online on: 17 January 2017
Article
Uptake of 111In-labeled fully human monoclonal antibody TSP-A18 reflects transferrin receptor expression in normal organs and tissues of mice
Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Fumiko Nomura, Hirokazu Satoh, Mitsuru Koizumi, Gene Kurosawa, Yoshikazu Kurosawa, Tsuneo Saga
Pages: 1529-1536 Published online on: 30 January 2017
Article
miR520c blocks EMT progression of human breast cancer cells by repressing STAT3
Nian Wang, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Feihu Ji, Changli Zhong, Tingmei Chen, Bing Li
Pages: 1537-1544 Published online on: 19 January 2017
Article
The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines
Toshifumi Doi, Takeshi Ishikawa, Tetsuya Okayama, Kaname Oka, Katsura Mizushima, Tomoyo Yasuda, Naoyuki Sakamoto, Kazuhiro Katada, Kazuhiro Kamada, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Yuji Naito, Yoshito Itoh
Pages: 1545-1554 Published online on: 23 January 2017
Article
TRIM29 promotes progression of thyroid carcinoma via activating P13K/AKT signaling pathway
Jinkai Xu, Zongyu Li, Qinghua Su, Jun Zhao, Jiancang Ma
Pages: 1555-1564 Published online on: 13 January 2017
Article
Emodin induces apoptosis of lung cancer cells through ER stress and the TRIB3/NF-κB pathway
Jin Su, Yan Yan, Jingkun Qu, Xuewen Xue, Zi Liu, Hui Cai
Pages: 1565-1572 Published online on: 07 February 2017
Case Report
First description of a double heterozygosity for BRCA1 and BRCA2 pathogenic variants in a French metastatic breast cancer patient: A case report
Guillaume Meynard, Laura Mansi, Pierre Lebahar, Cristian Villanueva, Elodie Klajer, Fabien Calcagno, Adrian Vilalta, Marie Chaix, Marie-Agnès Collonge-Rame, Céline Populaire, Marie-Paule Algros, Prudence Colpart, Julie Neidich, Xavier Pivot, Elsa Curtit
Pages: 1573-1578 Published online on: 03 February 2017
Article
Interaction between transcription factors PAX6/PAX6-5a and specific members of miR-183-96-182 cluster, may contribute to glioma progression in glioblastoma cell lines
Evangelos Pavlakis, Anton B. Tonchev, Ara Kaprelyan, Yavor Enchev, Anastassia Stoykova
Pages: 1579-1592 Published online on: 30 January 2017
Article
MicroRNA-194 represses glioma cell epithelial‑to‑mesenchymal transition by targeting Bmi1
Xi Zhang, Chunyan Wei, Jin Li, Jiali Liu, Jianqiang Qu
Pages: 1593-1600 Published online on: 17 January 2017
Article
Calpain inhibitors ameliorate muscle wasting in a cachectic mouse model bearing CT26 colorectal adenocarcinoma
Xing-Yu Lin, Si-Zeng Chen
Pages: 1601-1610 Published online on: 20 January 2017
Article
Osthole inhibits the tumorigenesis of hepatocellular carcinoma cells
Zhi-Kun Lin, Jia Liu, Guo-Qiang Jiang, Guang Tan, Peng Gong, Hai-Feng Luo, Hui-Min Li, Jian Du, Zhen Ning, Yi Xin, Zhong-Yu Wang
Pages: 1611-1618 Published online on: 24 January 2017
Article
Inhibition of RAB1A suppresses epithelial-mesenchymal transition and proliferation of triple-negative breast cancer cells
Hui Xu, Mingping Qian, Bingkun Zhao, Chenyang Wu, Niraj Maskey, Hongming Song, Dengfeng Li, Jialu Song, Kaiyao Hua, Lin Fang
Pages: 1619-1626 Published online on: 25 January 2017
Article
E3 ubiquitin ligase FBW7α inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E
Ming Li, Ling Ouyang, Zhigang Zheng, Dan Xiang, Aijun Ti, Leihua Li, Yuzhen Dan, Chundong Yu, Wengang Li
Pages: 1627-1636 Published online on: 07 February 2017
Article
Effect of evodiamine and berberine on the interaction between DNMTs and target microRNAs during malignant transformation of the colon by TGF-β1
Chao Huang, Hong Liu, Xiu-Li Gong, Li-Yun Wu, Bin Wen
Pages: 1637-1645 Published online on: 17 January 2017
Article
MicroRNA-133b is regulated by TAp63 while no gene mutation is present in colorectal cancer
Yifei Chen, Yi Zhang, Jianhuai He, Ying Fu, Changwei Lin, Xiaorong Li
Pages: 1646-1652 Published online on: 16 January 2017
Article
Core‑shell lipid polymer nanoparticles for combined chemo and gene therapy of childhood head and neck cancers
Tiesong Zhang, Jing Ma, Chao Li, Ken Lin, Fan Lou, Hongchao Jiang, Yingqin Gao, Yanli Yang, Cheng Ming, Biao Ruan
Pages: 1653-1661 Published online on: 13 January 2017
Article
Calcium release induced by 2-pyridinecarboxaldehyde thiosemicarbazone and its copper complex contributes to tumor cell death
Yun Fu, Youxun Liu, Jiangang Wang, Cuiping Li, Sufeng Zhou, Yun Yang, Pingxin Zhou, Chengbiao Lu, Changzheng Li
Pages: 1662-1670 Published online on: 20 January 2017
Article
Somatic mutational spectrum analysis in a prospective series of 104 gastrointestinal stromal tumors
David Guenat, Olivier Deroo, Sandrine Magnin, Loïc Chaigneau, Franck Monnien, Christophe Borg, Christiane Mougin, Jean-François Emile, Jean-Luc Prétet
Pages: 1671-1681 Published online on: 17 January 2017
Article
MicroRNA-30d inhibits the migration and invasion of human esophageal squamous cell carcinoma cells via the post‑transcriptional regulation of enhancer of zeste homolog 2
Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Hong‑Gang Wang, Jia-Ling Zhang, Wei Yan, Tian-Heng Ma
Pages: 1682-1690 Published online on: 25 January 2017
Article
MicroRNA-520c inhibits glioma cell migration and invasion by the suppression of transforming growth factor-β receptor type 2
Shengli Hu, Huibin Chen, Yuqiang Zhang, Chaojia Wang, Kaijun Liu, Hui Wang, Jie Luo
Pages: 1691-1697 Published online on: 03 February 2017
Article
MicroRNA-9 limits hepatic fibrosis by suppressing the activation and proliferation of hepatic stellate cells by directly targeting MRP1/ABCC1 Retraction in /10.3892/or.2023.8590
Jie Sun, Huanying Zhang, Liying Li, Lianfeng Yu, Lifang Fu
Pages: 1698-1706 Published online on: 17 January 2017
Article
Expression of phospholipase C isozymes in human breast cancer and their clinical significance
Shuo Cai, Ping-Hui Sun, Jeyna Resaul, Lei Shi, Aihua Jiang, Lucy K. Satherley, Eleri L. Davies, Fiona Ruge, Anthony Douglas-Jones, Wen G. Jiang, Lin Ye
Pages: 1707-1715 Published online on: 20 January 2017
Article
A hepatic stem cell vaccine is superior to an embryonic stem cell vaccine in the prophylaxis and treatment of murine hepatocarcinoma
Qi Zheng, Yichao Zheng, Jing Chen, Jia You, Yueyong Zhu, Yurui Liu, Jia Ji Jiang
Pages: 1716-1724 Published online on: 17 January 2017
Article
Astragaloside IV inhibits metastasis in hepatoma cells through the suppression of epithelial-mesenchymal transition via the Akt/GSK-3β/β-catenin pathway
Cheng-Dong Qin, De-Ning Ma, Zheng-Gang Ren, Xiao-Dong Zhu, Cheng-Hao Wang, Ying-Cong Wang, Bo-Gen Ye, Man-Qing Cao, Dong-Mei Gao, Zhao-You Tang
Pages: 1725-1735 Published online on: 19 January 2017
Article
Analysis of gene expression profiles of non-small cell lung cancer at different stages reveals significantly altered biological functions and candidate genes
Jin Wang, Jianxiang Song, Zhengya Gao, Xudong Huo, Yajun Zhang, Wencai Wang, Jianwei Qi, Shiying Zheng
Pages: 1736-1746 Published online on: 17 January 2017
Article
MicroRNA-187 promotes growth and metastasis of gastric cancer by inhibiting FOXA2
Cong Li, Sumei Lu, Yubin Shi
Pages: 1747-1755 Published online on: 16 January 2017
Article
Synergistic combination of YS-1 and adriamycin inhibits human renal cancer through ERK1/2 signaling pathway in vitro and in vivo
Xiaowen Yu, Qingqing Yang, Sensen Lin, Shengtao Yuan, Li Sun
Pages: 1756-1764 Published online on: 16 January 2017
Article
Lectin PCL inhibits the Warburg effect of PC3 cells by combining with EGFR and inhibiting HK2
Hong Zhang, Xia Du, Ting-Ting Sun, Chun-Liu Wang, Ye Li, Shou-Zhen Wu
Pages: 1765-1771 Published online on: 16 January 2017
Article
miR-217 suppresses proliferation, migration, and invasion promoting apoptosis via targeting MTDH in hepatocellular carcinoma
Mao Zhang, Min Li, Na Li, Zilang Zhang, Ning Liu, Xiaoyu Han, Qincheng Liu, Caixian Liao
Pages: 1772-1778 Published online on: 24 January 2017
Article
Interleukin-17A promotes esophageal adenocarcinoma cell invasiveness through ROS-dependent, NF-κB-mediated MMP-2/9 activation
Dong Liu, Rong Zhang, Jie Wu, Yansong Pu, Xiaoran Yin, Yan Cheng, Jing Wu, Cheng Feng, Yumei Luo, Jun Zhang
Pages: 1779-1785 Published online on: 07 February 2017
Article
Carboxamide analog ITR-284 evokes apoptosis and inhibits migration ability in human lung adenocarcinoma A549 cells
Jai-Sing Yang, Chia-An Lin, Chi-Cheng Lu, Yen-Fang Wen, Fuu-Jen Tsai, Shih-Chang Tsai
Pages: 1786-1792 Published online on: 16 January 2017
Article
Endophytic fungi from mangrove inhibit lung cancer cell growth and angiogenesis in vitro Corrigendum in /10.3892/or.2023.8608
Xin Liu, Xin Wu, Yuefan Ma, Wenzhang Zhang, Liang Hu, Xiaowei Feng, Xiangyong Li, Xudong Tang
Pages: 1793-1803 Published online on: 16 January 2017
Article
Circular RNA and gene expression profiles in gastric cancer based on microarray chip technology
Weiguo Sui, Zhoufang Shi, Wen Xue, Minglin Ou, Ying Zhu, Jiejing Chen, Hua Lin, Fuhua Liu, Yong Dai
Pages: 1804-1814 Published online on: 01 February 2017
Article
Reversal of P-gp-mediated multidrug resistance in colon cancer by cinobufagin
Zeting Yuan, Xiaojing Shi, Yanyan Qiu, Tingting Jia, Xia Yuan, Yu Zou, Cheng Liu, Hui Yu, Yuxia Yuan, Xue He, Ke Xu, Peihao Yin
Pages: 1815-1825 Published online on: 30 January 2017
Article
Overexpression of salusin-β is associated with poor prognosis in ovarian cancer
Qian Zhang, Wen-Ming Chen, Xin-Xin Zhang, Hu-Xiang Zhang, Han-Chu Wang, Fei-Yun Zheng, Fang-Fang Zhu
Pages: 1826-1832 Published online on: 07 February 2017
Article
Resveratrol enhances the radiosensitivity of nasopharyngeal carcinoma cells by downregulating E2F1
Yuhui Tan, Xianli Wei, Wenyin Zhang, Xiaolan Wang, Kun Wang, Biaoyan Du, Jianyong Xiao
Pages: 1833-1841 Published online on: 30 January 2017
Article
Cytokines, inducers and inhibitors modulate MMP-2 and MMP‑9 secretion by human Fanconi anemia immortalized fibroblasts
M. W. Roomi, T. Kalinovsky, M. Rath, A. Niedzwiecki
Pages: 1842-1848 Published online on: 16 January 2017
Article
MicroRNA-361-5p inhibits epithelial-to-mesenchymal transition of glioma cells through targeting Twist1
Xi Zhang, Chunyan Wei, Jin Li, Jiali Liu, Jianqiang Qu
Pages: 1849-1856 Published online on: 25 January 2017
Article
miR-365 targets ADAM10 and suppresses the cell growth and metastasis of hepatocellular carcinoma Retraction in /10.3892/or.2022.8402
Yahui Liu, Wei Zhang, Songyang Liu, Kai Liu, Bai Ji, Yingchao Wang
Pages: 1857-1864 Published online on: 06 February 2017
Article
Rhein exhibits antitumorigenic effects by interfering with the interaction between prolyl isomerase Pin1 and c-Jun
Jin Hyoung Cho, Jung-Il Chae, Jung-Hyun Shim
Pages: 1865-1872 Published online on: 07 February 2017
Article
Exposure to TNF‑α combined with TGF‑β induces carcinogenesis in vitro via NF-κB/Twist axis
Weilei Dong, Shuwen Sun, Xiaocheng Cao, Yinghong Cui, A. Chen, Xiang Li, Jiansong Zhang, Jianguo Cao, Yifeng Wang
Pages: 1873-1882 Published online on: 16 January 2017
Article
Low uptake of fluorodeoxyglucose in positron emission tomography/computed tomography in ovarian clear cell carcinoma may reflect glutaminolysis of its cancer stem cell-like properties
Masakazu Sato, Kei Kawana, Katsuyuki Adachi, Asaha Fujimoto, Ayumi Taguchi, Tomona Fujikawa, Mitsuyo Yoshida, Hiroe Nakamura, Haruka Nishida, Tomoko Inoue, Juri Ogishima, Satoko Eguchi, Aki Yamashita, Kensuke Tomio, Takahide Arimoto, Osamu Wada-Hiraike, Katsutoshi Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii
Pages: 1883-1888 Published online on: 20 January 2017
Article
MICA/IL-12: A novel bifunctional protein for killer cell activation
Ashlee Tietje, Xi Yang, Xianzhong Yu, Yanzhang Wei
Pages: 1889-1895 Published online on: 16 January 2017
Article
Knockdown of COBRA1 decreases the proliferation and migration of hepatocellular carcinoma cells
Eman El Zeneini, Sarah Kamel, Mahmoud El-Meteini, Asma Amleh
Pages: 1896-1906 Published online on: 19 January 2017
Article
Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells
M. Waheed Roomi, Tatiana Kalinovsky, Matthias Rath, Aleksandra Niedzwiecki
Pages: 1907-1913 Published online on: 19 January 2017
Article
Inhibition of hTERT in pancreatic cancer cells by pristimerin involves suppression of epigenetic regulators of gene transcription
Dorrah Deeb, Xiaohua Gao, Yong Bo Liu, Yiguan Zhang, Jiajiu Shaw, Frederick A. Valeriote, Subhash C. Gautam
Pages: 1914-1920 Published online on: 23 January 2017
Correction
