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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2017 Volume 37 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Biology and function of glypican-3 as a candidate for early cancerous transformation of hepatocytes in hepatocellular carcinoma (Review)

Mauro Montalbano, Jeremias Georgiadis, Ashlyn L. Masterson, Joshua T. McGuire, Janika Prajapati, Ali Shirafkan, Cristiana Rastellini, Luca Cicalese
Pages: 1291-1300
Published online on: 18 January 2017

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Review

New insights and future perspectives in the therapeutic strategy of adrenocortical carcinoma (Review)

Antonio Stigliano, Lidia Cerquetti, Pina Lardo, Elisa Petrangeli, Vincenzo Toscano
Pages: 1301-1311
Published online on: 07 February 2017

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Review

Diets link metabolic syndrome and colorectal cancer development (Review)

Jirakrit Saetang, Surasak Sangkhathat
Pages: 1312-1320
Published online on: 18 January 2017

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Review

Effects of different mycotoxins on humans, cell genome and their involvement in cancer (Review)

Mowaffaq Adam Ahmed Adam, Yasser M. Tabana, Khirun Binti Musa, Doblin Anak Sandai
Pages: 1321-1336
Published online on: 06 February 2017

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Review

Radiological biomarkers for assessing response to locoregional therapies in hepatocellular carcinoma: From morphological to functional imaging (Review)

Xiao-Dan Ye, Zuguo Yuan, Jian Zhang, Zheng Yuan
Pages: 1337-1346
Published online on: 03 February 2017

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Review Open Access

Determining EGFR-TKI sensitivity of G719X and other uncommon EGFR mutations in non-small cell lung cancer: Perplexity and solution (Review)

Kaidi Li, Maojun Yang, Naixin Liang, Shanqing Li
Pages: 1347-1358
Published online on: 30 January 2017

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Review Open Access

Long non-coding RNAs act as regulators of cell autophagy in diseases (Review)

Zhijie Xu, Yuanliang Yan, Long Qian, Zhicheng Gong
Pages: 1359-1366
Published online on: 01 February 2017

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Article Open Access

In vitro long-term treatment with MAPK inhibitors induces melanoma cells with resistance plasticity to inhibitors while retaining sensitivity to CD8 T cells

Florencia Paula Madorsky Rowdo, Antonela Barón, Erika María von Euw, José Mordoh
Pages: 1367-1378
Published online on: 13 January 2017

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Article Open Access

Analysis of chromosomal radiosensitivity of healthy BRCA2 mutation carriers and non-carriers in BRCA families with the G2 micronucleus assay

Annelot Baert, Julie Depuydt, Tom Van Maerken, Bruce Poppe, Fransiska Malfait, Tim Van Damme, Sylvia De Nobele, Gianpaolo Perletti, Kim De Leeneer, Kathleen B.M. Claes, Anne Vral
Pages: 1379-1386
Published online on: 25 January 2017

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Article Open Access

Targeting ROCK2 rather than ROCK1 inhibits Ewing sarcoma malignancy

Rosa Simona Pinca, Maria Cristina Manara, Valentina Chiadini, Piero Picci, Cinzia Zucchini, Katia Scotlandi
Pages: 1387-1393
Published online on: 20 January 2017

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Article Open Access

Tanshinone IIA suppresses gastric cancer cell proliferation and migration by downregulation of FOXM1

Jiao Yu, Xiaoxia Wang, Yuhua Li, Bin Tang
Pages: 1394-1400
Published online on: 30 January 2017

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Article Open Access

Role of miR-647 in human gastric cancer suppression

Wenlong Cao, Weiyuan Wei, Zexu Zhan, Dongyi Xie, Yubo Xie, Qiang Xiao
Pages: 1401-1411
Published online on: 17 January 2017

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Article Open Access

ELF5 in epithelial ovarian carcinoma tissues and biological behavior in ovarian carcinoma cells

Hongchao Yan, Linglin Qiu, Xiaolei Xie, He Yang, Yongli Liu, Xiaoman Lin, Hongxiang Huang
Pages: 1412-1418
Published online on: 02 February 2017

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Article Open Access

Inhibiting PLK1 induces autophagy of acute myeloid leukemia cells via mammalian target of rapamycin pathway dephosphorylation

Yan-Fang Tao, Zhi-Heng Li, Wei-Wei Du, Li-Xiao Xu, Jun-Li Ren, Xiao-Lu Li, Fang Fang, Yi Xie, Mei Li, Guang-Hui Qian, Yan-Hong Li, Yi-Ping Li, Gang Li, Yi Wu, Xing Feng, Jian Wang, Wei-Qi He, Shao-Yan Hu, Jun Lu, Jian Pan
Pages: 1419-1429
Published online on: 02 February 2017

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Article Open Access

Involvement of EZH2 in aerobic glycolysis of prostate cancer through miR-181b/HK2 axis

Tao Tao, Ming Chen, Ranran Jiang, Han Guan, Yeqing Huang, Huan Su, Qiang Hu, Xu Han, Jun Xiao
Pages: 1430-1436
Published online on: 07 February 2017

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Article

Upregulation of miR-21 expression is a valuable predicator of advanced clinicopathological features and poor prognosis in patients with renal cell carcinoma through the p53/p21‑cyclin E2‑Bax/caspase-3 signaling pathway

Zhihong Liu, You Lu, Yingmin Xiao, Yipin Lu
Pages: 1437-1444
Published online on: 24 January 2017

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Article

miR-922 regulates CYLD expression and promotes the cell proliferation of human hepatocellular carcinoma

Jianping Liu, Zheng Su, Yunjie Zeng, Huayao Zhang, Shanglin Yang, Gaojie Liu
Pages: 1445-1450
Published online on: 07 February 2017

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Article

NHE1 is upregulated in gastric cancer and regulates gastric cancer cell proliferation, migration and invasion Corrigendum in /10.3892/or.2019.7055

Rui Xie, Haibo Wang, Hai Jin, Guorong Wen, Biguang Tuo, Jingyu Xu
Pages: 1451-1460
Published online on: 18 January 2017

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Article

Exploration of bladder cancer molecular mechanisms based on miRNA-mRNA regulatory network

Wenfeng Li, Jia Liu, Di Zou, Xiaye Cai, Jingying Wang, Jinmeng Wang, Li Zhu, Liang Zhao, Rongying Ou, Yunsheng Xu
Pages: 1461-1468
Published online on: 07 February 2017

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Article

miR-181a-5p, an inducer of Wnt-signaling, facilitates cell proliferation in acute lymphoblastic leukemia

Xiaoming Lyu, Jinbang Li, Xi Yun, Rui Huang, Xubin Deng, Yingping Wang, Youming Chen, Gang Xiao
Pages: 1469-1476
Published online on: 06 February 2017

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Article

Characterization of the microRNA profile in early-stage cervical squamous cell carcinoma by next-generation sequencing

Wansong Lin, Mei Feng, Guilin Chen, Zhifeng Zhou, Jieyu Li, Yunbin Ye
Pages: 1477-1486
Published online on: 16 January 2017

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Article

Downregulation of OCLN and GAS1 in clear cell renal cell carcinoma

André Luis Giacometti Conceição, Camila Tainah Da Silva, Rodolfo Miglioli Badial, Marina Curado Valsechi, Bruna Stuqui, Jéssica Domingues Gonçalves, Miriam Galvonas Jasiulionis, Marilia De Freitas Calmon, Paula Rahal
Pages: 1487-1496
Published online on: 31 January 2017

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Article

Ginsenoside‑Rg5 treatment inhibits apoptosis of chondrocytes and degradation of cartilage matrix in a rat model of osteoarthritis

Ping Zhang
Pages: 1497-1502
Published online on: 19 January 2017

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Article

Downregulation of leucine‑rich‑α‑2‑glycoprotein 1 expression is associated with the tumorigenesis of head and neck squamous cell carcinoma

Yongping Wang, Chen Chen, Qingquan Hua, Lei Wang, Fen Li, Man Li, Zhidan Mei, Tao Zhou, Bokui Xiao, Zezhang Tao
Pages: 1503-1510
Published online on: 17 January 2017

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Article

Overexpression of ARF1 is associated with cell proliferation and migration through PI3K signal pathway in ovarian cancer

Guifang Gu, Yannan Chen, Chengwei Duan, Linsen Zhou, Caiwen Chen, Jie Chen, Jialin Cheng, Nannan Shi, Yunfeng Jin, Qinghua Xi, Jianxin Zhong
Pages: 1511-1520
Published online on: 18 January 2017

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Article

Cripto-1 promotes epithelial-mesenchymal transition in prostate cancer via Wnt/β-catenin signaling Corrigendum in /10.3892/or.2024.8734

Yan Liu, Zhenbang Qin, Kuo Yang, Ranlu Liu, Yong Xu
Pages: 1521-1528
Published online on: 17 January 2017

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Article

Uptake of 111In-labeled fully human monoclonal antibody TSP-A18 reflects transferrin receptor expression in normal organs and tissues of mice

Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Fumiko Nomura, Hirokazu Satoh, Mitsuru Koizumi, Gene Kurosawa, Yoshikazu Kurosawa, Tsuneo Saga
Pages: 1529-1536
Published online on: 30 January 2017

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Article

miR520c blocks EMT progression of human breast cancer cells by repressing STAT3

Nian Wang, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Feihu Ji, Changli Zhong, Tingmei Chen, Bing Li
Pages: 1537-1544
Published online on: 19 January 2017

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Article

The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines

Toshifumi Doi, Takeshi Ishikawa, Tetsuya Okayama, Kaname Oka, Katsura Mizushima, Tomoyo Yasuda, Naoyuki Sakamoto, Kazuhiro Katada, Kazuhiro Kamada, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Yuji Naito, Yoshito Itoh
Pages: 1545-1554
Published online on: 23 January 2017

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Article

TRIM29 promotes progression of thyroid carcinoma via activating P13K/AKT signaling pathway

Jinkai Xu, Zongyu Li, Qinghua Su, Jun Zhao, Jiancang Ma
Pages: 1555-1564
Published online on: 13 January 2017

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Article

Emodin induces apoptosis of lung cancer cells through ER stress and the TRIB3/NF-κB pathway

Jin Su, Yan Yan, Jingkun Qu, Xuewen Xue, Zi Liu, Hui Cai
Pages: 1565-1572
Published online on: 07 February 2017

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Case Report

First description of a double heterozygosity for BRCA1 and BRCA2 pathogenic variants in a French metastatic breast cancer patient: A case report

Guillaume Meynard, Laura Mansi, Pierre Lebahar, Cristian Villanueva, Elodie Klajer, Fabien Calcagno, Adrian Vilalta, Marie Chaix, Marie-Agnès Collonge-Rame, Céline Populaire, Marie-Paule Algros, Prudence Colpart, Julie Neidich, Xavier Pivot, Elsa Curtit
Pages: 1573-1578
Published online on: 03 February 2017

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Article

Interaction between transcription factors PAX6/PAX6-5a and specific members of miR-183-96-182 cluster, may contribute to glioma progression in glioblastoma cell lines

Evangelos Pavlakis, Anton B. Tonchev, Ara Kaprelyan, Yavor Enchev, Anastassia Stoykova
Pages: 1579-1592
Published online on: 30 January 2017

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Article

MicroRNA-194 represses glioma cell epithelial‑to‑mesenchymal transition by targeting Bmi1

Xi Zhang, Chunyan Wei, Jin Li, Jiali Liu, Jianqiang Qu
Pages: 1593-1600
Published online on: 17 January 2017

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Article

Calpain inhibitors ameliorate muscle wasting in a cachectic mouse model bearing CT26 colorectal adenocarcinoma

Xing-Yu Lin, Si-Zeng Chen
Pages: 1601-1610
Published online on: 20 January 2017

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Article

Osthole inhibits the tumorigenesis of hepatocellular carcinoma cells

Zhi-Kun Lin, Jia Liu, Guo-Qiang Jiang, Guang Tan, Peng Gong, Hai-Feng Luo, Hui-Min Li, Jian Du, Zhen Ning, Yi Xin, Zhong-Yu Wang
Pages: 1611-1618
Published online on: 24 January 2017

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Article

Inhibition of RAB1A suppresses epithelial-mesenchymal transition and proliferation of triple-negative breast cancer cells

Hui Xu, Mingping Qian, Bingkun Zhao, Chenyang Wu, Niraj Maskey, Hongming Song, Dengfeng Li, Jialu Song, Kaiyao Hua, Lin Fang
Pages: 1619-1626
Published online on: 25 January 2017

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Article

E3 ubiquitin ligase FBW7α inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E

Ming Li, Ling Ouyang, Zhigang Zheng, Dan Xiang, Aijun Ti, Leihua Li, Yuzhen Dan, Chundong Yu, Wengang Li
Pages: 1627-1636
Published online on: 07 February 2017

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Article

Effect of evodiamine and berberine on the interaction between DNMTs and target microRNAs during malignant transformation of the colon by TGF-β1

Chao Huang, Hong Liu, Xiu-Li Gong, Li-Yun Wu, Bin Wen
Pages: 1637-1645
Published online on: 17 January 2017

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Article

MicroRNA-133b is regulated by TAp63 while no gene mutation is present in colorectal cancer

Yifei Chen, Yi Zhang, Jianhuai He, Ying Fu, Changwei Lin, Xiaorong Li
Pages: 1646-1652
Published online on: 16 January 2017

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Article

Core‑shell lipid polymer nanoparticles for combined chemo and gene therapy of childhood head and neck cancers

Tiesong Zhang, Jing Ma, Chao Li, Ken Lin, Fan Lou, Hongchao Jiang, Yingqin Gao, Yanli Yang, Cheng Ming, Biao Ruan
Pages: 1653-1661
Published online on: 13 January 2017

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Article

Calcium release induced by 2-pyridinecarboxaldehyde thiosemicarbazone and its copper complex contributes to tumor cell death

Yun Fu, Youxun Liu, Jiangang Wang, Cuiping Li, Sufeng Zhou, Yun Yang, Pingxin Zhou, Chengbiao Lu, Changzheng Li
Pages: 1662-1670
Published online on: 20 January 2017

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Article

Somatic mutational spectrum analysis in a prospective series of 104 gastrointestinal stromal tumors

David Guenat, Olivier Deroo, Sandrine Magnin, Loïc Chaigneau, Franck Monnien, Christophe Borg, Christiane Mougin, Jean-François Emile, Jean-Luc Prétet
Pages: 1671-1681
Published online on: 17 January 2017

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Article

MicroRNA-30d inhibits the migration and invasion of human esophageal squamous cell carcinoma cells via the post‑transcriptional regulation of enhancer of zeste homolog 2

Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Hong‑Gang Wang, Jia-Ling Zhang, Wei Yan, Tian-Heng Ma
Pages: 1682-1690
Published online on: 25 January 2017

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Article

MicroRNA-520c inhibits glioma cell migration and invasion by the suppression of transforming growth factor-β receptor type 2

Shengli Hu, Huibin Chen, Yuqiang Zhang, Chaojia Wang, Kaijun Liu, Hui Wang, Jie Luo
Pages: 1691-1697
Published online on: 03 February 2017

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Article

MicroRNA-9 limits hepatic fibrosis by suppressing the activation and proliferation of hepatic stellate cells by directly targeting MRP1/ABCC1 Retraction in /10.3892/or.2023.8590

Jie Sun, Huanying Zhang, Liying Li, Lianfeng Yu, Lifang Fu
Pages: 1698-1706
Published online on: 17 January 2017

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Article

Expression of phospholipase C isozymes in human breast cancer and their clinical significance

Shuo Cai, Ping-Hui Sun, Jeyna Resaul, Lei Shi, Aihua Jiang, Lucy K. Satherley, Eleri L. Davies, Fiona Ruge, Anthony Douglas-Jones, Wen G. Jiang, Lin Ye
Pages: 1707-1715
Published online on: 20 January 2017

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Article

A hepatic stem cell vaccine is superior to an embryonic stem cell vaccine in the prophylaxis and treatment of murine hepatocarcinoma

Qi Zheng, Yichao Zheng, Jing Chen, Jia You, Yueyong Zhu, Yurui Liu, Jia Ji Jiang
Pages: 1716-1724
Published online on: 17 January 2017

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Article

Astragaloside IV inhibits metastasis in hepatoma cells through the suppression of epithelial-mesenchymal transition via the Akt/GSK-3β/β-catenin pathway

Cheng-Dong Qin, De-Ning Ma, Zheng-Gang Ren, Xiao-Dong Zhu, Cheng-Hao Wang, Ying-Cong Wang, Bo-Gen Ye, Man-Qing Cao, Dong-Mei Gao, Zhao-You Tang
Pages: 1725-1735
Published online on: 19 January 2017

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Article

Analysis of gene expression profiles of non-small cell lung cancer at different stages reveals significantly altered biological functions and candidate genes

Jin Wang, Jianxiang Song, Zhengya Gao, Xudong Huo, Yajun Zhang, Wencai Wang, Jianwei Qi, Shiying Zheng
Pages: 1736-1746
Published online on: 17 January 2017

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Article

MicroRNA-187 promotes growth and metastasis of gastric cancer by inhibiting FOXA2

Cong Li, Sumei Lu, Yubin Shi
Pages: 1747-1755
Published online on: 16 January 2017

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Article

Synergistic combination of YS-1 and adriamycin inhibits human renal cancer through ERK1/2 signaling pathway in vitro and in vivo

Xiaowen Yu, Qingqing Yang, Sensen Lin, Shengtao Yuan, Li Sun
Pages: 1756-1764
Published online on: 16 January 2017

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Article

Lectin PCL inhibits the Warburg effect of PC3 cells by combining with EGFR and inhibiting HK2

Hong Zhang, Xia Du, Ting-Ting Sun, Chun-Liu Wang, Ye Li, Shou-Zhen Wu
Pages: 1765-1771
Published online on: 16 January 2017

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Article

miR-217 suppresses proliferation, migration, and invasion promoting apoptosis via targeting MTDH in hepatocellular carcinoma

Mao Zhang, Min Li, Na Li, Zilang Zhang, Ning Liu, Xiaoyu Han, Qincheng Liu, Caixian Liao
Pages: 1772-1778
Published online on: 24 January 2017

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Article

Interleukin-17A promotes esophageal adenocarcinoma cell invasiveness through ROS-dependent, NF-κB-mediated MMP-2/9 activation

Dong Liu, Rong Zhang, Jie Wu, Yansong Pu, Xiaoran Yin, Yan Cheng, Jing Wu, Cheng Feng, Yumei Luo, Jun Zhang
Pages: 1779-1785
Published online on: 07 February 2017

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Article

Carboxamide analog ITR-284 evokes apoptosis and inhibits migration ability in human lung adenocarcinoma A549 cells

Jai-Sing Yang, Chia-An Lin, Chi-Cheng Lu, Yen-Fang Wen, Fuu-Jen Tsai, Shih-Chang Tsai
Pages: 1786-1792
Published online on: 16 January 2017

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Article

Endophytic fungi from mangrove inhibit lung cancer cell growth and angiogenesis in vitro Corrigendum in /10.3892/or.2023.8608

Xin Liu, Xin Wu, Yuefan Ma, Wenzhang Zhang, Liang Hu, Xiaowei Feng, Xiangyong Li, Xudong Tang
Pages: 1793-1803
Published online on: 16 January 2017

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Article

Circular RNA and gene expression profiles in gastric cancer based on microarray chip technology

Weiguo Sui, Zhoufang Shi, Wen Xue, Minglin Ou, Ying Zhu, Jiejing Chen, Hua Lin, Fuhua Liu, Yong Dai
Pages: 1804-1814
Published online on: 01 February 2017

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Article

Reversal of P-gp-mediated multidrug resistance in colon cancer by cinobufagin

Zeting Yuan, Xiaojing Shi, Yanyan Qiu, Tingting Jia, Xia Yuan, Yu Zou, Cheng Liu, Hui Yu, Yuxia Yuan, Xue He, Ke Xu, Peihao Yin
Pages: 1815-1825
Published online on: 30 January 2017

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Overexpression of salusin-β is associated with poor prognosis in ovarian cancer

Qian Zhang, Wen-Ming Chen, Xin-Xin Zhang, Hu-Xiang Zhang, Han-Chu Wang, Fei-Yun Zheng, Fang-Fang Zhu
Pages: 1826-1832
Published online on: 07 February 2017

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Resveratrol enhances the radiosensitivity of nasopharyngeal carcinoma cells by downregulating E2F1

Yuhui Tan, Xianli Wei, Wenyin Zhang, Xiaolan Wang, Kun Wang, Biaoyan Du, Jianyong Xiao
Pages: 1833-1841
Published online on: 30 January 2017

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Article

Cytokines, inducers and inhibitors modulate MMP-2 and MMP‑9 secretion by human Fanconi anemia immortalized fibroblasts

M. W. Roomi, T. Kalinovsky, M. Rath, A. Niedzwiecki
Pages: 1842-1848
Published online on: 16 January 2017

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Article

MicroRNA-361-5p inhibits epithelial-to-mesenchymal transition of glioma cells through targeting Twist1

Xi Zhang, Chunyan Wei, Jin Li, Jiali Liu, Jianqiang Qu
Pages: 1849-1856
Published online on: 25 January 2017

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miR-365 targets ADAM10 and suppresses the cell growth and metastasis of hepatocellular carcinoma Retraction in /10.3892/or.2022.8402

Yahui Liu, Wei Zhang, Songyang Liu, Kai Liu, Bai Ji, Yingchao Wang
Pages: 1857-1864
Published online on: 06 February 2017

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Article

Rhein exhibits antitumorigenic effects by interfering with the interaction between prolyl isomerase Pin1 and c-Jun

Jin Hyoung Cho, Jung-Il Chae, Jung-Hyun Shim
Pages: 1865-1872
Published online on: 07 February 2017

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Article

Exposure to TNF‑α combined with TGF‑β induces carcinogenesis in vitro via NF-κB/Twist axis

Weilei Dong, Shuwen Sun, Xiaocheng Cao, Yinghong Cui, A. Chen, Xiang Li, Jiansong Zhang, Jianguo Cao, Yifeng Wang
Pages: 1873-1882
Published online on: 16 January 2017

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Article

Low uptake of fluorodeoxyglucose in positron emission tomography/computed tomography in ovarian clear cell carcinoma may reflect glutaminolysis of its cancer stem cell-like properties

Masakazu Sato, Kei Kawana, Katsuyuki Adachi, Asaha Fujimoto, Ayumi Taguchi, Tomona Fujikawa, Mitsuyo Yoshida, Hiroe Nakamura, Haruka Nishida, Tomoko Inoue, Juri Ogishima, Satoko Eguchi, Aki Yamashita, Kensuke Tomio, Takahide Arimoto, Osamu Wada-Hiraike, Katsutoshi Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii
Pages: 1883-1888
Published online on: 20 January 2017

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Article

MICA/IL-12: A novel bifunctional protein for killer cell activation

Ashlee Tietje, Xi Yang, Xianzhong Yu, Yanzhang Wei
Pages: 1889-1895
Published online on: 16 January 2017

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Article

Knockdown of COBRA1 decreases the proliferation and migration of hepatocellular carcinoma cells

Eman El Zeneini, Sarah Kamel, Mahmoud El-Meteini, Asma Amleh
Pages: 1896-1906
Published online on: 19 January 2017

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Article

Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells

M. Waheed Roomi, Tatiana Kalinovsky, Matthias Rath, Aleksandra Niedzwiecki
Pages: 1907-1913
Published online on: 19 January 2017

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Article

Inhibition of hTERT in pancreatic cancer cells by pristimerin involves suppression of epigenetic regulators of gene transcription

Dorrah Deeb, Xiaohua Gao, Yong Bo Liu, Yiguan Zhang, Jiajiu Shaw, Frederick A. Valeriote, Subhash C. Gautam
Pages: 1914-1920
Published online on: 23 January 2017

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Correction Open Access

[Corrigendum] Loss of Runt‑related transcription factor 3 induces resistance to 5‑fluorouracil and cisplatin in hepatocellular carcinoma

Junro Kataoka, Hidenori Shiraha, Shigeru Horiguchi, Hiroaki Sawahara, Daisuke Uchida, Teruya Nagahara, Masaya Iwamuro, Hiroki Morimoto, Yasuto Takeuchi, Kenji Kuwaki, Hideki Onishi, Shinichiro Nakamura, Akinobu Takaki, Kazuhiro Nouso, Takahito Yagi, Kazuhide Yamamoto, Hiroyuki Okada
Pages: 1921-1921
Published online on: 03 February 2017

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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