|
1
|
Wei WI and Sham JS: Nasopharyngeal
carcinoma. Lancet. 365:2041–2054. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lo KW, Chung GT and To KF: Deciphering the
molecular genetic basis of NPC through molecular, cytogenetic, and
epigenetic approaches. Semin Cancer Biol. 22:79–86. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Lee AW: Contribution of radiotherapy to
function preservation and cancer outcome in primary treatment of
nasopharyngeal carcinoma. World J Surg. 27:838–843. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Chen WC, McBride WH, Chen SM, Lee KF,
Hwang TZ, Jung SM, Shau H, Liao SK, Hong JH and Chen MF: Prediction
of poor survival by cyclooxygenase-2 in patients with T4
nasopharyngeal cancer treated by radiation therapy: clinical and in
vitro studies. Head Neck. 27:503–512. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Loomans HA and Andl CD: Intertwining of
activin A and TGFβ signaling: dual roles in cancer progression and
cancer cell invasion. Cancers (Basel). 7:70–91. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Roberts AB and Wakefield LM: The two faces
of transforming growth factor beta in carcinogenesis. Proc Natl
Acad Sci USA. 100:8621–8623. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Katsuno Y, Lamouille S and Derynck R:
TGF-β signaling and epithelial-mesenchymal transition in cancer
progression. Curr Opin Oncol. 25:76–84. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Zhang P, Liu H, Xia F, Zhang QW, Zhang YY,
Zhao Q, Chao ZH, Jiang ZW and Jiang CC: Epithelial-mesenchymal
transition is necessary for acquired resistance to cisplatin and
increases the metastatic potential of nasopharyngeal carcinoma
cells. Int J Mol Med. 33:151–159. 2014.PubMed/NCBI
|
|
9
|
Kumar A, Chopra Ekavali K, Mukherjee M,
Pottabathini R and Dhull DK: Current knowledge and pharmacological
profile of berberine: an update. Eur J Pharmacol. 761:288–297.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tang F, Wang D, Duan C, Huang D, Wu Y,
Chen Y, Wang W, Xie C, Meng J, Wang L, et al: Berberine inhibits
metastasis of nasopharyngeal carcinoma 5–8F cells by targeting Rho
kinase-mediated Ezrin phosphorylation at threonine 567. J Biol
Chem. 284:27456–27466. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Tsang CM, Cheung YC, Lui VW, Yip YL, Zhang
G, Lin VW, Cheung KC, Feng Y and Tsao SW: Berberine suppresses
tumorigenicity and growth of nasopharyngeal carcinoma cells by
inhibiting STAT3 activation induced by tumor associated
fibroblasts. BMC Cancer. 13:6192013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Zhang C, Yang X, Zhang Q, Yang B, Xu L,
Qin Q, Zhu H, Liu J, Cai J, Tao G, et al: Berberine radiosensitizes
human nasopharyngeal carcinoma by suppressing hypoxia-inducible
factor-1α expression. Acta Otolaryngol. 134:185–192. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang J, Kang M, Qin YT, Wei ZX, Xiao JJ
and Wang RS: Sp1 is over-expressed in nasopharyngeal cancer and is
a poor prognostic indicator for patients receiving radiotherapy.
Int J Clin Exp Pathol. 8:6936–6943. 2015.PubMed/NCBI
|
|
14
|
Chen W and Hu GH: Biomarkers for enhancing
the radiosensitivity of nasopharyngeal carcinoma. Cancer Biol Med.
12:23–32. 2015.PubMed/NCBI
|
|
15
|
Liu Q, Jiang H, Liu Z, Wang Y, Zhao M, Hao
C, Feng S, Guo H, Xu B, Yang Q, et al: Berberine radiosensitizes
human esophageal cancer cells by downregulating homologous
recombination repair protein RAD51. PLoS One. 6:e234272011.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Wang J, Liu Q and Yang Q:
Radiosensitization effects of berberine on human breast cancer
cells. Int J Mol Med. 30:1166–1172. 2012.PubMed/NCBI
|
|
17
|
Yang X, Yang B, Cai J, Zhang C, Zhang Q,
Xu L, Qin Q, Zhu H, Ma J, Tao G, et al: Berberine enhances
radiosensitivity of esophageal squamous cancer by targeting HIF-1α
in vitro and in vivo. Cancer Biol Ther. 14:1068–1073. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhang Q, Zhang C, Yang X, Yang B, Wang J,
Kang Y, Wang Z, Li D, Huang G, Ma Z, et al: Berberine inhibits the
expression of hypoxia induction factor-1alpha and increases the
radiosensitivity of prostate cancer. Diagn Pathol. 9:982014.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Davie JR, He S, Li L, Sekhavat A, Espino
P, Drobic B, Dunn KL, Sun JM, Chen HY, Yu J, et al: Nuclear
organization and chromatin dynamics - Sp1, Sp3 and histone
deacetylases. Adv Enzyme Regul. 48:189–208. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wang HB, Liu GH, Zhang H, Xing S, Hu LJ,
Zhao WF, Xie B, Li MZ, Zeng BH, Li Y, et al: Sp1 and c-Myc regulate
transcription of BMI1 in nasopharyngeal carcinoma. FEBS J.
280:2929–2944. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang JP, Zhang H, Wang HB, Li YX, Liu GH,
Xing S, Li MZ and Zeng MS: Down-regulation of Sp1 suppresses cell
proliferation, clonogenicity and the expressions of stem cell
markers in nasopharyngeal carcinoma. J Transl Med. 12:2222014.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yang CR, Wilson-Van Patten C, Planchon SM,
Wuerzberger-Davis SM, Davis TW, Cuthill S, Miyamoto S and Boothman
DA: Coordinate modulation of Sp1, NF-kappa B, and p53 in confluent
human malignant melanoma cells after ionizing radiation. FASEB J.
14:379–390. 2000.PubMed/NCBI
|
|
23
|
Marie-Egyptienne DT, Lohse I and Hill RP:
Cancer stem cells, the epithelial to mesenchymal transition (EMT)
and radioresistance: potential role of hypoxia. Cancer Lett.
341:63–72. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhang X, Zheng L, Sun Y, Wang T and Wang
B: Tangeretin enhances radiosensitivity and inhibits the
radiation-induced epithelial-mesenchymal transition of gastric
cancer cells. Oncol Rep. 34:302–310. 2015.PubMed/NCBI
|
|
25
|
Qi HW, Xin LY, Xu X, Ji XX and Fan LH:
Epithelial-to-mesenchymal transition markers to predict response of
Berberine in suppressing lung cancer invasion and metastasis. J
Transl Med. 12:222014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Chu SC, Yu CC, Hsu LS, Chen KS, Su MY and
Chen PN: Berberine reverses epithelial-to-mesenchymal transition
and inhibits metastasis and tumor-induced angiogenesis in human
cervical cancer cells. Mol Pharmacol. 86:609–623. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Liu CH, Tang WC, Sia P, Huang CC, Yang PM,
Wu MH, Lai IL and Lee KH: Berberine inhibits the metastatic ability
of prostate cancer cells by suppressing epithelial-to-mesenchymal
transition (EMT)-associated genes with predictive and prognostic
relevance. Int J Med Sci. 12:63–71. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Li CH, Wu DF, Ding H, Zhao Y, Zhou KY and
Xu DF: Berberine hydrochloride impact on physiological processes
and modulation of twist levels in nasopharyngeal carcinoma CNE-1
cells. Asian Pac J Cancer Prev. 15:1851–1857. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Theys J, Jutten B, Habets R, Paesmans K,
Groot AJ, Lambin P, Wouters BG, Lammering G and Vooijs M:
E-cadherin loss associated with EMT promotes radioresistance in
human tumor cells. Radiother Oncol. 99:392–397. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kolesnikoff N, Attema JL, Roslan S, Bert
AG, Schwarz QP, Gregory PA and Goodall GJ: Specificity protein 1
(Sp1) maintains basal epithelial expression of the miR-200 family:
implications for epithelial-mesenchymal transition. J Biol Chem.
289:11194–11205. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Sung WJ, Kim KH, Kim YJ, Chang YC, Lee IH
and Park KK: Antifibrotic effect of synthetic Smad/Sp1 chimeric
decoy oligodeoxynucleotide through the regulation of epithelial
mesenchymal transition in unilateral ureteral obstruction model of
mice. Exp Mol Pathol. 95:136–143. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Nam EH, Lee Y, Park YK, Lee JW and Kim S:
ZEB2 upregulates integrin α5 expression through cooperation with
Sp1 to induce invasion during epithelial-mesenchymal transition of
human cancer cells. Carcinogenesis. 33:563–571. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Kim WY, Jang JY, Jeon YK, Chung DH, Kim YG
and Kim CW: Syntenin increases the invasiveness of small cell lung
cancer cells by activating p38, AKT, focal adhesion kinase and SP1.
Exp Mol Med. 46:e902014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Kong LM, Liao CG, Zhang Y, Xu J, Li Y,
Huang W, Zhang Y, Bian H and Chen ZN: A regulatory loop involving
miR-22, Sp1, and c-Myc modulates CD147 expression in breast cancer
invasion and metastasis. Cancer Res. 74:3764–3778. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Zhao J, Ye W, Wu J, Liu L, Yang L, Gao L,
Chen B, Zhang F, Yang H and Li Y: Sp1-CD147 positive feedback loop
promotes the invasion ability of ovarian cancer. Oncol Rep.
34:67–76. 2015.PubMed/NCBI
|
|
36
|
Tan Y, Yin H, Zhang H, Fang J, Zheng W, Li
D, Li Y, Cao W, Sun C, Liang Y, et al: Sp1-driven up-regulation of
miR-19a decreases RHOB and promotes pancreatic cancer. Oncotarget.
6:17391–17403. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Jiang J, Lv X, Fan L, Huang G, Zhan Y,
Wang M and Lu H: MicroRNA-27b suppresses growth and invasion of
NSCLC cells by targeting Sp1. Tumour Biol. 35:10019–10023. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhang R, Luo H, Wang S, Chen W, Chen Z,
Wang HW, Chen Y, Yang J, Zhang X, Wu W, et al: MicroRNA-377
inhibited proliferation and invasion of human glioblastoma cells by
directly targeting specificity protein 1. Neuro-oncol.
16:1510–1522. 2014. View Article : Google Scholar : PubMed/NCBI
|
