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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April-2017 Volume 37 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Concurrence of chromosome 3 and 4 aberrations in human uveal melanoma

Eva Sipos, Kata Hegyi, Andrea Treszl, Zita Steiber, Gabor Mehes, Nikoletta Dobos, Klara Fodor, Gabor Olah, Lorant Szekvolgyi, Andrew V. Schally, Gabor Halmos
Pages: 1927-1934
Published online on: 08 March 2017

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Article Open Access

FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide

Jian Ma, Jianlei Li, Xiaoling Yao, Shuangjun Lin, Ye Gu, Jianfang Xu, Zixin Deng, Wei Ma, Haiping Zhang
Pages: 1935-1942
Published online on: 01 March 2017

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Article Open Access

Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma

Masafumi Chiba, Hiroo Imazu, Masayuki Kato, Keiichi Ikeda, Hiroshi Arakawa, Tomohiro Kato, Kazuki Sumiyama, Sadamu Homma
Pages: 1943-1952
Published online on: 21 February 2017

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Article Open Access

EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer

Ding-Ping Sun, Chia-Lang Fang, Han-Kun Chen, Kuo-Shan Wen, You-Cheng Hseu, Shih-Ting Hung, Yih-Huei Uen, Kai-Yuan Lin
Pages: 1953-1960
Published online on: 14 February 2017

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Article Open Access

Pleomorphic adenoma gene like-2 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human colorectal adenocarcinoma

Yong-Peng Wang, Peng-Tao Guo, Zhi Zhu, Hao Zhang, Yan Xu, Yu-Ze Chen, Fang Liu, Si-Ping Ma
Pages: 1961-1970
Published online on: 02 March 2017

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Article Open Access

Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism

Tao Shan, Shuo Chen, Xi Chen, Wan Run Lin, Wei Li, Jiancang Ma, Tao Wu, Xijuan Cui, Hong Ji, Yiming Li, Ya'an Kang
Pages: 1971-1979
Published online on: 28 February 2017

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Article Open Access

miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM

Yuyan Guo, Wenze Sun, Tuotuo Gong, Yanlan Chai, Juan Wang, Beina Hui, Yi Li, Liping Song, Ying Gao
Pages: 1980-1988
Published online on: 14 February 2017

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Article Open Access

Chemosensitizing effect of shRNA-mediated ERCC1 silencing on a Xuanwei lung adenocarcinoma cell line and its clinical significance

Weiwei Wang, Lijun Zhang, Liang Liu, Yongfa Zheng, Yong Zhang, Siyuan Yang, Rongliang Shi, Shaojia Wang
Pages: 1989-1997
Published online on: 14 February 2017

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Article Open Access

G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways

Yizhuo Wang, Huijie Xiao, Haitao Wu, Cheng Yao, Hua He, Chang Wang, Wei Li
Pages: 1998-2006
Published online on: 13 March 2017

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Article Open Access

Activation of the CRABPII/RAR pathway by curcumin induces retinoic acid mediated apoptosis in retinoic acid resistant breast cancer cells

Padmamalini Thulasiraman, Galen Garriga, Veena Danthuluri, Daniel J. McAndrews, Imran Q. Mohiuddin
Pages: 2007-2015
Published online on: 08 March 2017

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Article

Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro

Zhang-Feng Zhong, Wen Tan, Ke Tian, Hua Yu, Wen-An Qiang, Yi-Tao Wang
Pages: 2016-2024
Published online on: 10 February 2017

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Article

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity

Masashi Shiiba, Hitomi Yamagami, Ayumi Yamamoto, Yasuyuki Minakawa, Atsushi Okamoto, Atsushi Kasamatsu, Yosuke Sakamoto, Katsuhiro Uzawa, Yuichi Takiguchi, Hideki Tanzawa
Pages: 2025-2032
Published online on: 01 March 2017

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Article

ADAM9 functions as a promoter of gastric cancer growth which is negatively and post-transcriptionally regulated by miR-126

Junqing Wang, Yunyun Zhou, Xiaochun Fei, Xuehua Chen, Jiqi Yan, Bingya Liu, Zhenggang Zhu
Pages: 2033-2040
Published online on: 16 February 2017

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Article

Octreotide inhibits the proliferation of gastric cancer cells through P300-HAT activity and the interaction of ZAC and P300

Liping Wang, Xin Huang, Yurong Chai, Liyang Zou, Matthew Chedrawe, Yi Ding
Pages: 2041-2048
Published online on: 14 February 2017

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Article

Atorvastatin prolongs the lifespan of radiation‑induced reactive oxygen species in PC-3 prostate cancer cells to enhance the cell killing effect

Hao Yu, Shao-Qian Sun, Xiao-Bin Gu, Wen Wang, Xian-Shu Gao
Pages: 2049-2056
Published online on: 14 February 2017

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Article

Dysregulation of TMPRSS3 and TNFRSF11B correlates with tumorigenesis and poor prognosis in patients with breast cancer

Ping Luo, Gaixia Lu, Lin‑Lin Fan, Xiaoming Zhong, Huiqiong Yang, Ruting Xie, Zhongwei Lv, Qian‑Zhou Lv, Da Fu, Li‑Xin Yang, Yushui Ma
Pages: 2057-2062
Published online on: 14 February 2017

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Article

Tumor-penetrating peptide fused to a pro-apoptotic peptide facilitates effective gastric cancer therapy

Ying Huang, Xihan Li, Huizi Sha, Lianru Zhang, Xinyu Bian, Xiao Han, Baorui Liu
Pages: 2063-2070
Published online on: 10 February 2017

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Article

Upregulation of miR-137 reverses sorafenib resistance and cancer-initiating cell phenotypes by degrading ANT2 in hepatocellular carcinoma

Ai-Qing Lu, Bin Lv, Fei Qiu, Xiao-Yun Wang, Xiao-Hua Cao
Pages: 2071-2078
Published online on: 10 March 2017

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Article

A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells

Xiaoli Dai, Jing Liu, Yin Nian, Ming-Hua Qiu, Ying Luo, Jihong Zhang
Pages: 2079-2086
Published online on: 14 February 2017

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Article

Long non-coding RNA MALAT1 interacts with miR-124 and modulates tongue cancer growth by targeting JAG1 Retraction in /10.3892/or.2018.6688

Tong-Han Zhang, Li-Zhong Liang, Xiao-Ling Liu, Ji-Nan Wu, Kui Su, Jue-Yao Chen, Qiao-Yi Zheng, Hong-Zhang Huang, Gui-Qing Liao
Pages: 2087-2094
Published online on: 14 February 2017

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Article

CXCL8 induces epithelial-mesenchymal transition in colon cancer cells via the PI3K/Akt/NF-κB signaling pathway

Tao Shen, Zhibin Yang, Xianshuo Cheng, Youchuan Xiao, Kun Yu, Xinyi Cai, Cuifeng Xia, Yunfeng Li
Pages: 2095-2100
Published online on: 14 February 2017

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Article

Identification of novel cancer fusion genes using chromosome breakpoint screening

Kate Hua, Chin-Hui Lin, Ya-Lun Chen, Chi-Hung Lin, Yueh‑Hsin Ping, Yuh-Shan Jou, Chian-Feng Chen
Pages: 2101-2108
Published online on: 06 March 2017

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Article

Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism

Chao Wang, Huan Wang, Yaqian Zhang, Wei Guo, Cong Long, Jingchao Wang, Limei Liu, Xiaoping Sun
Pages: 2109-2120
Published online on: 02 March 2017

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Article

Cx32 reverses epithelial-mesenchymal transition in doxorubicin-resistant hepatocellular carcinoma

Meiling Yu, Guangshu Han, Benquan Qi, Xiaoxiang Wu
Pages: 2121-2128
Published online on: 17 February 2017

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Article

Overexpression of miR-203 increases the sensitivity of NSCLC A549/H460 cell lines to cisplatin by targeting Dickkopf-1 Retraction in /10.3892/or.2022.8461

Ruirui Cheng, Chunya Lu, Guojun Zhang, Guowei Zhang, Guoqiang Zhao
Pages: 2129-2136
Published online on: 13 March 2017

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Article

High expression of PINK1 promotes proliferation and chemoresistance of NSCLC

Rui Zhang, Jun Gu, Jie Chen, Jun Ni, Jieru Hung, Zhiwen Wang, Xiaochen Zhang, Jian Feng, Lili Ji
Pages: 2137-2146
Published online on: 02 March 2017

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Article

Knockdown of GATAD2A suppresses cell proliferation in thyroid cancer in vitro

Zongping Wang, Jie Kang, Xianzhao Deng, Bomin Guo, Bo Wu, Youben Fan
Pages: 2147-2152
Published online on: 10 February 2017

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Article

Absence of Malat1 does not prevent DEN-induced hepatocarcinoma in mice

Stéphanie Miard, Marie-Josée Girard, Philippe Joubert, Sophie Carter, Amy Gonzales, Huiping Guo, Benjamin Morpurgo, Louise Boivin, Andrei Golovko, Frédéric Picard
Pages: 2153-2160
Published online on: 20 February 2017

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Article

Enhanced expression of PKM2 associates with the biological properties of cancer stem cells from A549 human lung cancer cells

Chang-Ying Guo, Chen Yan, Lan Luo, Shinji Goto, Yoshishige Urata, Jian-Jun Xu, Xiao-Ming Wen, Yu-Kang Kuang, Fang-Fang Tou, Tao-Sheng Li
Pages: 2161-2166
Published online on: 10 February 2017

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Article

High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma

Rong Liang, Yan Lin, Jia-Zhou Ye, Xue-Xin Yan, Zhi-Hui Liu, Yong-Qiang Li, Xiao-Ling Luo, Hai-Hong Ye
Pages: 2167-2176
Published online on: 15 February 2017

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Article

Combined treatment with vitamin C and methotrexate inhibits triple-negative breast cancer cell growth by increasing H2O2 accumulation and activating caspase-3 and p38 pathways

Ching-Wen Wu, Hsiao-Chun Liu, Yung-Luen Yu, Yu-Ting Hung, Chyou-Wei Wei, Giou-Teng Yiang
Pages: 2177-2184
Published online on: 10 February 2017

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Article

MicroRNA-365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Pages: 2185-2192
Published online on: 16 February 2017

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Article

miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1 Corrigendum in /10.3892/or.2019.7057

Yan Li, Lifen Zhao, Nana Li, Yuan Miao, Huimin Zhou, Li Jia
Pages: 2193-2200
Published online on: 17 February 2017

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Article

AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis Corrigendum in /10.3892/or.2017.5482

Yun Jung Choi, Ji Hye Kim, Jin Kyung Rho, Joong Sun Kim, Chang-Min Choi, Woo Sung Kim, Jaekyoung Son, Jae Cheol Lee
Pages: 2201-2208
Published online on: 01 March 2017

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Article

Runx2 downregulation, migration and proliferation inhibition in melanoma cells treated with BEL β-trefoil

Massimiliano Perduca, Luca Dalle Carbonare, Michele Bovi, Giulio Innamorati, Samuele Cheri, Chiara Cavallini, Maria Teresa Scupoli, Antonio Mori, Maria Teresa Valenti
Pages: 2209-2214
Published online on: 06 March 2017

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Article Open Access

TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma Corrigendum in /10.3892/or.2022.8411

Song Ye, Xin-Yi Zhao, Xiao-Ge Hu, Tang Li, Qiu-Ran Xu, Huan-Ming Yang, Dong-Sheng Huang, Liu Yang
Pages: 2215-2226
Published online on: 08 March 2017

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Article

Anti-hepatoma activities of ethyl acetate extract from Ampelopsis sinica root

Jia-Zhi Wang, Bi-Sheng Huang, Yan Cao, Ke-Li Chen, Juan Li
Pages: 2227-2236
Published online on: 13 March 2017

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Article

Paclitaxel induces apoptosis of esophageal squamous cell carcinoma cells by downregulating STAT3 phosphorylation at Ser727

Xiaolong Zhang, Xiaoyi Wu, Fangling Zhang, Shouyong Mo, Yuanyuan Lu, Wei Wei, Xiaoling Chen, Linhua Lan, Bin Lu, Yongzhang Liu
Pages: 2237-2244
Published online on: 13 March 2017

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Article

Knockdown of PARP6 or survivin promotes cell apoptosis and inhibits cell invasion of colorectal adenocarcinoma cells

Haipeng Wang, Shengguo Li, Xishun Luo, Zhike Song, Xiangkai Long, Xijia Zhu
Pages: 2245-2251
Published online on: 14 February 2017

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Article

GSH depletion and consequent AKT inhibition contribute to the Nrf2 knockdown-induced decrease in proliferation in glioblastoma U251 cells

Yue Jia, Han-Dong Wang, Qiang Wang, Hui Ding, He-Ming Wu, Hao Pan
Pages: 2252-2260
Published online on: 20 February 2017

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Article

FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression

Runze Shang, Meng Pu, Yu Li, Desheng Wang
Pages: 2261-2269
Published online on: 22 February 2017

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Article

Increased expression of HOXB9 in hepatocellular carcinoma predicts poor overall survival but a beneficial response to sorafenib

Naokazu Chiba, Yosuke Ozawa, Kosuke Hikita, Masaaki Okihara, Toru Sano, Koichi Tomita, Kiminori Takano, Shigeyuki Kawachi
Pages: 2270-2276
Published online on: 23 February 2017

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Article

Apigenin inhibits proliferation and invasion, and induces apoptosis and cell cycle arrest in human melanoma cells

Guangming Zhao, Xiaodong Han, Wei Cheng, Jing Ni, Yunfei Zhang, Jingrong Lin, Zhiqi Song
Pages: 2277-2285
Published online on: 14 February 2017

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Article

Epigenetic activation of WHSC1 functions as an oncogene and is associated with poor prognosis in cervical cancer

Zhuolian Yin, Yong Sun, Sufang Ge, Juxiang Sun
Pages: 2286-2294
Published online on: 17 February 2017

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Article

pSTAT5 and ERK exhibit different expression in myeloproliferative neoplasms

Ewa Wiśniewska-Chudy, Łukasz Szylberg, Grzegorz Dworacki, Ewa Mizera-Nyczak, Andrzej Marszałek
Pages: 2295-2307
Published online on: 24 February 2017

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Article

Roles of immune inhibitory molecule B7-H4 in cervical cancer

Sai Han, Yi Li, Jingjing Zhang, Lu Liu, Qian Chen, Qiuhong Qian, Shan Li, Youzhong Zhang
Pages: 2308-2316
Published online on: 01 March 2017

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Article

The anti-metastatic effect of baicalein on colorectal cancer

Yuxia Chai, Jizhong Xu, Baojun Yan
Pages: 2317-2323
Published online on: 10 February 2017

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Article

HPV16 oncogenes E6 or/and E7 may influence the methylation status of RASSFIA gene promoter region in cervical cancer cell line HT-3

Fufen Yin, Ning Wang, Shanshan Wang, Fengsheng Yu, Xin Sun, Xiao Yu, Bing Luo, Chengquan Zhao, Yankui Wang
Pages: 2324-2334
Published online on: 17 February 2017

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Article

Foxk2 inhibits non-small cell lung cancer epithelial-mesenchymal transition and proliferation through the repression of different key target genes

Shu Chen, Simin Jiang, Fen Hu, Yongjian Xu, Tao Wang, Qi Mei
Pages: 2335-2347
Published online on: 16 February 2017

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Article

Osthole enhances TRAIL-mediated apoptosis through downregulation of c-FLIP expression in renal carcinoma Caki cells

Kyoung-Jin Min, Min Ae Han, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon
Pages: 2348-2354
Published online on: 06 March 2017

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Article

Identification of the key genes implicated in the transformation of OLP to OSCC using RNA-sequencing

Qiaozhen Yang, Bin Guo, Hongying Sun, Jie Zhang, Shangfeng Liu, Saiyin Hexige, Xuedi Yu, Xiaxia Wang
Pages: 2355-2365
Published online on: 02 March 2017

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Article

Effects of 5-fluorouracil, adriamycin and irinotecan on HSC-39, a human scirrhous gastric cancer cell line

Rie Tamaki, Aya Kanai-Mori, Yuta Morishige, Atsushi Koike, Kazuyoshi Yanagihara, Fumio Amano
Pages: 2366-2374
Published online on: 20 February 2017

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Article

CIRH1A augments the proliferation of RKO colorectal cancer cells

Feng Guo, Jian-Jun Chen, Wei-Jun Tang
Pages: 2375-2381
Published online on: 08 March 2017

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Article

Silencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy

James Griffith, Daniel Andrade, Meghna Mehta, William Berry, Doris M. Benbrook, Natarajan Aravindan, Terence S. Herman, Rajagopal Ramesh, Anupama Munshi
Pages: 2382-2390
Published online on: 28 February 2017

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Article

FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation Corrigendum in /10.3892/or.2020.7842

Ke Xu, Zhenhao Zhang, Hua Pei, Huamin Wang, Liang Li, Qianfeng Xia
Pages: 2391-2397
Published online on: 16 February 2017

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Article

USP39 promotes colorectal cancer growth and metastasis through the Wnt/β-catenin pathway

Xianwen Yuan, Xitai Sun, Xiaolei Shi, Hao Wang, Guoyi Wu, Chunping Jiang, Decai Yu, Weiwei Zhang, Bin Xue, Yitao Ding
Pages: 2398-2404
Published online on: 15 February 2017

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Article

Actin-like protein 6A is a novel prognostic indicator promoting invasion and metastasis in osteosarcoma

Wei Sun, Wanchun Wang, Jian Lei, Hui Li, Yi Wu
Pages: 2405-2417
Published online on: 23 February 2017

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Article

Co-treatment of breast cancer cells with pharmacologic doses of 2-deoxy-D-glucose and metformin: Starving tumors

Ulrike Wokoun, Martin Hellriegel, Günter Emons, Carsten Gründker
Pages: 2418-2424
Published online on: 06 March 2017

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Article

Berberine sensitizes nasopharyngeal carcinoma cells to radiation through inhibition of Sp1 and EMT

Jun Wang, Min Kang, Qin Wen, Yu-Tao Qin, Zhu-Xin Wei, Jing-Jian Xiao, Ren-Sheng Wang
Pages: 2425-2432
Published online on: 13 March 2017

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Melatonin inhibits angiogenesis in SH-SY5Y human neuroblastoma cells by downregulation of VEGF

Alicia González, Alicia González-González, Carolina Alonso-González, Javier Menéndez-Menéndez, Carlos Martínez-Campa, Samuel Cos
Pages: 2433-2440
Published online on: 14 February 2017

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MicroRNA-134 suppresses cell proliferation in gastric cancer cells via targeting of GOLPH3

Yanqi Liu, Yanhong Sun, Aizhen Zhao
Pages: 2441-2448
Published online on: 02 March 2017

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MicroRNA-455-3p functions as a tumor suppressor by targeting eIF4E in prostate cancer

Yongxiang Zhao, Mingyu Yan, Ye Yun, Jianguo Zhang, Ruimin Zhang, Yan Li, Xiangming Wu, Qiang Liu, Wei Miao, Haishan Jiang
Pages: 2449-2458
Published online on: 13 March 2017

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Depletion of TFAP2E attenuates adriamycin-mediated apoptosis in human neuroblastoma cells

Reina Hoshi, Yosuke Watanabe, Yoshiaki Ishizuka, Takayuki Hirano, Eri Nagasaki-Maeoka, Shinsuke Yoshizawa, Shota Uekusa, Hiroyuki Kawashima, Kensuke Ohashi, Kiminobu Sugito, Noboru Fukuda, Hiroki Nagase, Masayoshi Soma, Toshinori Ozaki, Tsugumichi Koshinaga, Kyoko Fujiwara
Pages: 2459-2464
Published online on: 24 February 2017

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Stanniocalcin 1 promotes cell proliferation via cyclin E1/cyclin‑dependent kinase 2 in human prostate carcinoma

Yao Bai, Yichen Xiao, Yuanqing Dai, Xiong Chen, Dongjie Li, Xinji Tan, Xiaobo Zhang
Pages: 2465-2471
Published online on: 13 March 2017

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Tumor-associated macrophages favor C26 murine colon carcinoma cell proliferation in an oxidative stress-dependent manner

Lavinia Luput, Emilia Licarete, Alina Sesarman, Laura Patras, Marius Costel Alupei, Manuela Banciu
Pages: 2472-2480
Published online on: 17 February 2017

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Vinblastine differs from Taxol as it inhibits the malignant phenotypes of NSCLC cells by increasing the phosphorylation of Op18/stathmin

Fang Shen, Dan Long, Ting Yu, Xian Chen, Ying Liao, Yi Wu, Xuechi Lin
Pages: 2481-2489
Published online on: 20 February 2017

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Upregulation of microRNA-125b-5p is involved in the pathogenesis of osteoarthritis by downregulating SYVN1

Feng‑Xiao Ge, Haitao Li, Xin Yin
Pages: 2490-2496
Published online on: 24 February 2017

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Upregulation of p38 pathway accelerates proliferation and migration of MDA-MB-231 breast cancer cells

Hugo W. Huth, Daniel M. Santos, Humberto D. Gravina, Jarbas M. Resende, Alfredo M. Goes, Maria Elena de Lima, Catherine Ropert
Pages: 2497-2505
Published online on: 14 February 2017

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Article

Clinical and molecular assessment of regorafenib monotherapy

Nao Kakizawa, Koichi Suzuki, Taro Fukui, Yuji Takayama, Kosuke Ichida, Yuta Muto, Fumi Hasegawa, Fumiaki Watanabe, Rina Kikugawa, Shingo Tsujinaka, Kazushige Futsuhara, Yasuyuki Miyakura, Hiroshi Noda, Toshiki Rikiyama
Pages: 2506-2512
Published online on: 15 February 2017

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Article

miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway

Jie Xiao, Weifeng Yu, Kongzu Hu, Maoqiang Li, Jianwei Chen, Zhanchun Li
Pages: 2513-2521
Published online on: 02 March 2017

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Correction Open Access

[Corrigendum] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Pages: 2522-2522
Published online on: 15 February 2017

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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