Journal Articles
Article
Concurrence of chromosome 3 and 4 aberrations in human uveal melanoma
Eva Sipos, Kata Hegyi, Andrea Treszl, Zita Steiber, Gabor Mehes, Nikoletta Dobos, Klara Fodor, Gabor Olah, Lorant Szekvolgyi, Andrew V. Schally, Gabor Halmos
Pages: 1927-1934 Published online on: 08 March 2017
Article
FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide
Jian Ma, Jianlei Li, Xiaoling Yao, Shuangjun Lin, Ye Gu, Jianfang Xu, Zixin Deng, Wei Ma, Haiping Zhang
Pages: 1935-1942 Published online on: 01 March 2017
Article
Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma
Masafumi Chiba, Hiroo Imazu, Masayuki Kato, Keiichi Ikeda, Hiroshi Arakawa, Tomohiro Kato, Kazuki Sumiyama, Sadamu Homma
Pages: 1943-1952 Published online on: 21 February 2017
Article
EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer
Ding-Ping Sun, Chia-Lang Fang, Han-Kun Chen, Kuo-Shan Wen, You-Cheng Hseu, Shih-Ting Hung, Yih-Huei Uen, Kai-Yuan Lin
Pages: 1953-1960 Published online on: 14 February 2017
Article
Pleomorphic adenoma gene like-2 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human colorectal adenocarcinoma
Yong-Peng Wang, Peng-Tao Guo, Zhi Zhu, Hao Zhang, Yan Xu, Yu-Ze Chen, Fang Liu, Si-Ping Ma
Pages: 1961-1970 Published online on: 02 March 2017
Article
Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism
Tao Shan, Shuo Chen, Xi Chen, Wan Run Lin, Wei Li, Jiancang Ma, Tao Wu, Xijuan Cui, Hong Ji, Yiming Li, Ya'an Kang
Pages: 1971-1979 Published online on: 28 February 2017
Article
miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM
Yuyan Guo, Wenze Sun, Tuotuo Gong, Yanlan Chai, Juan Wang, Beina Hui, Yi Li, Liping Song, Ying Gao
Pages: 1980-1988 Published online on: 14 February 2017
Article
Chemosensitizing effect of shRNA-mediated ERCC1 silencing on a Xuanwei lung adenocarcinoma cell line and its clinical significance
Weiwei Wang, Lijun Zhang, Liang Liu, Yongfa Zheng, Yong Zhang, Siyuan Yang, Rongliang Shi, Shaojia Wang
Pages: 1989-1997 Published online on: 14 February 2017
Article
G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways
Yizhuo Wang, Huijie Xiao, Haitao Wu, Cheng Yao, Hua He, Chang Wang, Wei Li
Pages: 1998-2006 Published online on: 13 March 2017
Article
Activation of the CRABPII/RAR pathway by curcumin induces retinoic acid mediated apoptosis in retinoic acid resistant breast cancer cells
Padmamalini Thulasiraman, Galen Garriga, Veena Danthuluri, Daniel J. McAndrews, Imran Q. Mohiuddin
Pages: 2007-2015 Published online on: 08 March 2017
Article
Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro
Zhang-Feng Zhong, Wen Tan, Ke Tian, Hua Yu, Wen-An Qiang, Yi-Tao Wang
Pages: 2016-2024 Published online on: 10 February 2017
Article
Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity
Masashi Shiiba, Hitomi Yamagami, Ayumi Yamamoto, Yasuyuki Minakawa, Atsushi Okamoto, Atsushi Kasamatsu, Yosuke Sakamoto, Katsuhiro Uzawa, Yuichi Takiguchi, Hideki Tanzawa
Pages: 2025-2032 Published online on: 01 March 2017
Article
ADAM9 functions as a promoter of gastric cancer growth which is negatively and post-transcriptionally regulated by miR-126
Junqing Wang, Yunyun Zhou, Xiaochun Fei, Xuehua Chen, Jiqi Yan, Bingya Liu, Zhenggang Zhu
Pages: 2033-2040 Published online on: 16 February 2017
Article
Octreotide inhibits the proliferation of gastric cancer cells through P300-HAT activity and the interaction of ZAC and P300
Liping Wang, Xin Huang, Yurong Chai, Liyang Zou, Matthew Chedrawe, Yi Ding
Pages: 2041-2048 Published online on: 14 February 2017
Article
Atorvastatin prolongs the lifespan of radiation‑induced reactive oxygen species in PC-3 prostate cancer cells to enhance the cell killing effect
Hao Yu, Shao-Qian Sun, Xiao-Bin Gu, Wen Wang, Xian-Shu Gao
Pages: 2049-2056 Published online on: 14 February 2017
Article
Dysregulation of TMPRSS3 and TNFRSF11B correlates with tumorigenesis and poor prognosis in patients with breast cancer
Ping Luo, Gaixia Lu, Lin‑Lin Fan, Xiaoming Zhong, Huiqiong Yang, Ruting Xie, Zhongwei Lv, Qian‑Zhou Lv, Da Fu, Li‑Xin Yang, Yushui Ma
Pages: 2057-2062 Published online on: 14 February 2017
Article
Tumor-penetrating peptide fused to a pro-apoptotic peptide facilitates effective gastric cancer therapy
Ying Huang, Xihan Li, Huizi Sha, Lianru Zhang, Xinyu Bian, Xiao Han, Baorui Liu
Pages: 2063-2070 Published online on: 10 February 2017
Article
Upregulation of miR-137 reverses sorafenib resistance and cancer-initiating cell phenotypes by degrading ANT2 in hepatocellular carcinoma
Ai-Qing Lu, Bin Lv, Fei Qiu, Xiao-Yun Wang, Xiao-Hua Cao
Pages: 2071-2078 Published online on: 10 March 2017
Article
A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells
Xiaoli Dai, Jing Liu, Yin Nian, Ming-Hua Qiu, Ying Luo, Jihong Zhang
Pages: 2079-2086 Published online on: 14 February 2017
Article
Long non-coding RNA MALAT1 interacts with miR-124 and modulates tongue cancer growth by targeting JAG1 Retraction in /10.3892/or.2018.6688
Tong-Han Zhang, Li-Zhong Liang, Xiao-Ling Liu, Ji-Nan Wu, Kui Su, Jue-Yao Chen, Qiao-Yi Zheng, Hong-Zhang Huang, Gui-Qing Liao
Pages: 2087-2094 Published online on: 14 February 2017
Article
CXCL8 induces epithelial-mesenchymal transition in colon cancer cells via the PI3K/Akt/NF-κB signaling pathway
Tao Shen, Zhibin Yang, Xianshuo Cheng, Youchuan Xiao, Kun Yu, Xinyi Cai, Cuifeng Xia, Yunfeng Li
Pages: 2095-2100 Published online on: 14 February 2017
Article
Identification of novel cancer fusion genes using chromosome breakpoint screening
Kate Hua, Chin-Hui Lin, Ya-Lun Chen, Chi-Hung Lin, Yueh‑Hsin Ping, Yuh-Shan Jou, Chian-Feng Chen
Pages: 2101-2108 Published online on: 06 March 2017
Article
Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism
Chao Wang, Huan Wang, Yaqian Zhang, Wei Guo, Cong Long, Jingchao Wang, Limei Liu, Xiaoping Sun
Pages: 2109-2120 Published online on: 02 March 2017
Article
Cx32 reverses epithelial-mesenchymal transition in doxorubicin-resistant hepatocellular carcinoma
Meiling Yu, Guangshu Han, Benquan Qi, Xiaoxiang Wu
Pages: 2121-2128 Published online on: 17 February 2017
Article
Overexpression of miR-203 increases the sensitivity of NSCLC A549/H460 cell lines to cisplatin by targeting Dickkopf-1 Retraction in /10.3892/or.2022.8461
Ruirui Cheng, Chunya Lu, Guojun Zhang, Guowei Zhang, Guoqiang Zhao
Pages: 2129-2136 Published online on: 13 March 2017
Article
High expression of PINK1 promotes proliferation and chemoresistance of NSCLC
Rui Zhang, Jun Gu, Jie Chen, Jun Ni, Jieru Hung, Zhiwen Wang, Xiaochen Zhang, Jian Feng, Lili Ji
Pages: 2137-2146 Published online on: 02 March 2017
Article
Knockdown of GATAD2A suppresses cell proliferation in thyroid cancer in vitro
Zongping Wang, Jie Kang, Xianzhao Deng, Bomin Guo, Bo Wu, Youben Fan
Pages: 2147-2152 Published online on: 10 February 2017
Article
Absence of Malat1 does not prevent DEN-induced hepatocarcinoma in mice
Stéphanie Miard, Marie-Josée Girard, Philippe Joubert, Sophie Carter, Amy Gonzales, Huiping Guo, Benjamin Morpurgo, Louise Boivin, Andrei Golovko, Frédéric Picard
Pages: 2153-2160 Published online on: 20 February 2017
Article
Enhanced expression of PKM2 associates with the biological properties of cancer stem cells from A549 human lung cancer cells
Chang-Ying Guo, Chen Yan, Lan Luo, Shinji Goto, Yoshishige Urata, Jian-Jun Xu, Xiao-Ming Wen, Yu-Kang Kuang, Fang-Fang Tou, Tao-Sheng Li
Pages: 2161-2166 Published online on: 10 February 2017
Article
High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma
Rong Liang, Yan Lin, Jia-Zhou Ye, Xue-Xin Yan, Zhi-Hui Liu, Yong-Qiang Li, Xiao-Ling Luo, Hai-Hong Ye
Pages: 2167-2176 Published online on: 15 February 2017
Article
Combined treatment with vitamin C and methotrexate inhibits triple-negative breast cancer cell growth by increasing H2O2 accumulation and activating caspase-3 and p38 pathways
Ching-Wen Wu, Hsiao-Chun Liu, Yung-Luen Yu, Yu-Ting Hung, Chyou-Wei Wei, Giou-Teng Yiang
Pages: 2177-2184 Published online on: 10 February 2017
Article
MicroRNA-365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3
Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Pages: 2185-2192 Published online on: 16 February 2017
Article
miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1
Yan Li, Lifen Zhao, Nana Li, Yuan Miao, Huimin Zhou, Li Jia
Pages: 2193-2200 Published online on: 17 February 2017
Article
AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis Corrigendum in /10.3892/or.2017.5482
Yun Jung Choi, Ji Hye Kim, Jin Kyung Rho, Joong Sun Kim, Chang-Min Choi, Woo Sung Kim, Jaekyoung Son, Jae Cheol Lee
Pages: 2201-2208 Published online on: 01 March 2017
Article
Runx2 downregulation, migration and proliferation inhibition in melanoma cells treated with BEL β-trefoil
Massimiliano Perduca, Luca Dalle Carbonare, Michele Bovi, Giulio Innamorati, Samuele Cheri, Chiara Cavallini, Maria Teresa Scupoli, Antonio Mori, Maria Teresa Valenti
Pages: 2209-2214 Published online on: 06 March 2017
Article
TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma Corrigendum in /10.3892/or.2022.8411
Song Ye, Xin-Yi Zhao, Xiao-Ge Hu, Tang Li, Qiu-Ran Xu, Huan-Ming Yang, Dong-Sheng Huang, Liu Yang
Pages: 2215-2226 Published online on: 08 March 2017
Article
Anti-hepatoma activities of ethyl acetate extract from Ampelopsis sinica root
Jia-Zhi Wang, Bi-Sheng Huang, Yan Cao, Ke-Li Chen, Juan Li
Pages: 2227-2236 Published online on: 13 March 2017
Article
Paclitaxel induces apoptosis of esophageal squamous cell carcinoma cells by downregulating STAT3 phosphorylation at Ser727
Xiaolong Zhang, Xiaoyi Wu, Fangling Zhang, Shouyong Mo, Yuanyuan Lu, Wei Wei, Xiaoling Chen, Linhua Lan, Bin Lu, Yongzhang Liu
Pages: 2237-2244 Published online on: 13 March 2017
Article
Knockdown of PARP6 or survivin promotes cell apoptosis and inhibits cell invasion of colorectal adenocarcinoma cells
Haipeng Wang, Shengguo Li, Xishun Luo, Zhike Song, Xiangkai Long, Xijia Zhu
Pages: 2245-2251 Published online on: 14 February 2017
Article
GSH depletion and consequent AKT inhibition contribute to the Nrf2 knockdown-induced decrease in proliferation in glioblastoma U251 cells
Yue Jia, Han-Dong Wang, Qiang Wang, Hui Ding, He-Ming Wu, Hao Pan
Pages: 2252-2260 Published online on: 20 February 2017
Article
FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression
Runze Shang, Meng Pu, Yu Li, Desheng Wang
Pages: 2261-2269 Published online on: 22 February 2017
Article
Increased expression of HOXB9 in hepatocellular carcinoma predicts poor overall survival but a beneficial response to sorafenib
Naokazu Chiba, Yosuke Ozawa, Kosuke Hikita, Masaaki Okihara, Toru Sano, Koichi Tomita, Kiminori Takano, Shigeyuki Kawachi
Pages: 2270-2276 Published online on: 23 February 2017
Article
Apigenin inhibits proliferation and invasion, and induces apoptosis and cell cycle arrest in human melanoma cells
Guangming Zhao, Xiaodong Han, Wei Cheng, Jing Ni, Yunfei Zhang, Jingrong Lin, Zhiqi Song
Pages: 2277-2285 Published online on: 14 February 2017
Article
Epigenetic activation of WHSC1 functions as an oncogene and is associated with poor prognosis in cervical cancer
Zhuolian Yin, Yong Sun, Sufang Ge, Juxiang Sun
Pages: 2286-2294 Published online on: 17 February 2017
Article
pSTAT5 and ERK exhibit different expression in myeloproliferative neoplasms
Ewa Wiśniewska-Chudy, Łukasz Szylberg, Grzegorz Dworacki, Ewa Mizera-Nyczak, Andrzej Marszałek
Pages: 2295-2307 Published online on: 24 February 2017
Article
Roles of immune inhibitory molecule B7-H4 in cervical cancer
Sai Han, Yi Li, Jingjing Zhang, Lu Liu, Qian Chen, Qiuhong Qian, Shan Li, Youzhong Zhang
Pages: 2308-2316 Published online on: 01 March 2017
Article
The anti-metastatic effect of baicalein on colorectal cancer
Yuxia Chai, Jizhong Xu, Baojun Yan
Pages: 2317-2323 Published online on: 10 February 2017
Article
HPV16 oncogenes E6 or/and E7 may influence the methylation status of RASSFIA gene promoter region in cervical cancer cell line HT-3
Fufen Yin, Ning Wang, Shanshan Wang, Fengsheng Yu, Xin Sun, Xiao Yu, Bing Luo, Chengquan Zhao, Yankui Wang
Pages: 2324-2334 Published online on: 17 February 2017
Article
Foxk2 inhibits non-small cell lung cancer epithelial-mesenchymal transition and proliferation through the repression of different key target genes
Shu Chen, Simin Jiang, Fen Hu, Yongjian Xu, Tao Wang, Qi Mei
Pages: 2335-2347 Published online on: 16 February 2017
Article
Osthole enhances TRAIL-mediated apoptosis through downregulation of c-FLIP expression in renal carcinoma Caki cells
Kyoung-Jin Min, Min Ae Han, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon
Pages: 2348-2354 Published online on: 06 March 2017
Article
Identification of the key genes implicated in the transformation of OLP to OSCC using RNA-sequencing
Qiaozhen Yang, Bin Guo, Hongying Sun, Jie Zhang, Shangfeng Liu, Saiyin Hexige, Xuedi Yu, Xiaxia Wang
Pages: 2355-2365 Published online on: 02 March 2017
Article
Effects of 5-fluorouracil, adriamycin and irinotecan on HSC-39, a human scirrhous gastric cancer cell line
Rie Tamaki, Aya Kanai-Mori, Yuta Morishige, Atsushi Koike, Kazuyoshi Yanagihara, Fumio Amano
Pages: 2366-2374 Published online on: 20 February 2017
Article
CIRH1A augments the proliferation of RKO colorectal cancer cells
Feng Guo, Jian-Jun Chen, Wei-Jun Tang
Pages: 2375-2381 Published online on: 08 March 2017
Article
Silencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy
James Griffith, Daniel Andrade, Meghna Mehta, William Berry, Doris M. Benbrook, Natarajan Aravindan, Terence S. Herman, Rajagopal Ramesh, Anupama Munshi
Pages: 2382-2390 Published online on: 28 February 2017
Article
FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation Corrigendum in /10.3892/or.2020.7842
Ke Xu, Zhenhao Zhang, Hua Pei, Huamin Wang, Liang Li, Qianfeng Xia
Pages: 2391-2397 Published online on: 16 February 2017
Article
USP39 promotes colorectal cancer growth and metastasis through the Wnt/β-catenin pathway
Xianwen Yuan, Xitai Sun, Xiaolei Shi, Hao Wang, Guoyi Wu, Chunping Jiang, Decai Yu, Weiwei Zhang, Bin Xue, Yitao Ding
Pages: 2398-2404 Published online on: 15 February 2017
Article
Actin-like protein 6A is a novel prognostic indicator promoting invasion and metastasis in osteosarcoma
Wei Sun, Wanchun Wang, Jian Lei, Hui Li, Yi Wu
Pages: 2405-2417 Published online on: 23 February 2017
Article
Co-treatment of breast cancer cells with pharmacologic doses of 2-deoxy-D-glucose and metformin: Starving tumors
Ulrike Wokoun, Martin Hellriegel, Günter Emons, Carsten Gründker
Pages: 2418-2424 Published online on: 06 March 2017
Article
Berberine sensitizes nasopharyngeal carcinoma cells to radiation through inhibition of Sp1 and EMT
Jun Wang, Min Kang, Qin Wen, Yu-Tao Qin, Zhu-Xin Wei, Jing-Jian Xiao, Ren-Sheng Wang
Pages: 2425-2432 Published online on: 13 March 2017
Article
Melatonin inhibits angiogenesis in SH-SY5Y human neuroblastoma cells by downregulation of VEGF
Alicia González, Alicia González-González, Carolina Alonso-González, Javier Menéndez-Menéndez, Carlos Martínez-Campa, Samuel Cos
Pages: 2433-2440 Published online on: 14 February 2017
Article
MicroRNA-134 suppresses cell proliferation in gastric cancer cells via targeting of GOLPH3
Yanqi Liu, Yanhong Sun, Aizhen Zhao
Pages: 2441-2448 Published online on: 02 March 2017
Article
MicroRNA-455-3p functions as a tumor suppressor by targeting eIF4E in prostate cancer
Yongxiang Zhao, Mingyu Yan, Ye Yun, Jianguo Zhang, Ruimin Zhang, Yan Li, Xiangming Wu, Qiang Liu, Wei Miao, Haishan Jiang
Pages: 2449-2458 Published online on: 13 March 2017
Article
Depletion of TFAP2E attenuates adriamycin-mediated apoptosis in human neuroblastoma cells
Reina Hoshi, Yosuke Watanabe, Yoshiaki Ishizuka, Takayuki Hirano, Eri Nagasaki-Maeoka, Shinsuke Yoshizawa, Shota Uekusa, Hiroyuki Kawashima, Kensuke Ohashi, Kiminobu Sugito, Noboru Fukuda, Hiroki Nagase, Masayoshi Soma, Toshinori Ozaki, Tsugumichi Koshinaga, Kyoko Fujiwara
Pages: 2459-2464 Published online on: 24 February 2017
Article
Stanniocalcin 1 promotes cell proliferation via cyclin E1/cyclin‑dependent kinase 2 in human prostate carcinoma
Yao Bai, Yichen Xiao, Yuanqing Dai, Xiong Chen, Dongjie Li, Xinji Tan, Xiaobo Zhang
Pages: 2465-2471 Published online on: 13 March 2017
Article
Tumor-associated macrophages favor C26 murine colon carcinoma cell proliferation in an oxidative stress-dependent manner
Lavinia Luput, Emilia Licarete, Alina Sesarman, Laura Patras, Marius Costel Alupei, Manuela Banciu
Pages: 2472-2480 Published online on: 17 February 2017
Article
Vinblastine differs from Taxol as it inhibits the malignant phenotypes of NSCLC cells by increasing the phosphorylation of Op18/stathmin
Fang Shen, Dan Long, Ting Yu, Xian Chen, Ying Liao, Yi Wu, Xuechi Lin
Pages: 2481-2489 Published online on: 20 February 2017
Article
Upregulation of microRNA-125b-5p is involved in the pathogenesis of osteoarthritis by downregulating SYVN1
Feng‑Xiao Ge, Haitao Li, Xin Yin
Pages: 2490-2496 Published online on: 24 February 2017
Article
Upregulation of p38 pathway accelerates proliferation and migration of MDA-MB-231 breast cancer cells
Hugo W. Huth, Daniel M. Santos, Humberto D. Gravina, Jarbas M. Resende, Alfredo M. Goes, Maria Elena de Lima, Catherine Ropert
Pages: 2497-2505 Published online on: 14 February 2017
Article
Clinical and molecular assessment of regorafenib monotherapy
Nao Kakizawa, Koichi Suzuki, Taro Fukui, Yuji Takayama, Kosuke Ichida, Yuta Muto, Fumi Hasegawa, Fumiaki Watanabe, Rina Kikugawa, Shingo Tsujinaka, Kazushige Futsuhara, Yasuyuki Miyakura, Hiroshi Noda, Toshiki Rikiyama
Pages: 2506-2512 Published online on: 15 February 2017
Article
miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway
Jie Xiao, Weifeng Yu, Kongzu Hu, Maoqiang Li, Jianwei Chen, Zhanchun Li
Pages: 2513-2521 Published online on: 02 March 2017
Correction
