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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April-2017 Volume 37 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Concurrence of chromosome 3 and 4 aberrations in human uveal melanoma

Eva Sipos, Kata Hegyi, Andrea Treszl, Zita Steiber, Gabor Mehes, Nikoletta Dobos, Klara Fodor, Gabor Olah, Lorant Szekvolgyi, Andrew V. Schally, Gabor Halmos
Pages: 1927-1934
Published online on: 08 March 2017

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Article Open Access

FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide

Jian Ma, Jianlei Li, Xiaoling Yao, Shuangjun Lin, Ye Gu, Jianfang Xu, Zixin Deng, Wei Ma, Haiping Zhang
Pages: 1935-1942
Published online on: 01 March 2017

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Article Open Access

Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma

Masafumi Chiba, Hiroo Imazu, Masayuki Kato, Keiichi Ikeda, Hiroshi Arakawa, Tomohiro Kato, Kazuki Sumiyama, Sadamu Homma
Pages: 1943-1952
Published online on: 21 February 2017

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Article Open Access

EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer

Ding-Ping Sun, Chia-Lang Fang, Han-Kun Chen, Kuo-Shan Wen, You-Cheng Hseu, Shih-Ting Hung, Yih-Huei Uen, Kai-Yuan Lin
Pages: 1953-1960
Published online on: 14 February 2017

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Article Open Access

Pleomorphic adenoma gene like-2 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human colorectal adenocarcinoma

Yong-Peng Wang, Peng-Tao Guo, Zhi Zhu, Hao Zhang, Yan Xu, Yu-Ze Chen, Fang Liu, Si-Ping Ma
Pages: 1961-1970
Published online on: 02 March 2017

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Article Open Access

Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism

Tao Shan, Shuo Chen, Xi Chen, Wan Run Lin, Wei Li, Jiancang Ma, Tao Wu, Xijuan Cui, Hong Ji, Yiming Li, Ya'an Kang
Pages: 1971-1979
Published online on: 28 February 2017

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Article Open Access

miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM

Yuyan Guo, Wenze Sun, Tuotuo Gong, Yanlan Chai, Juan Wang, Beina Hui, Yi Li, Liping Song, Ying Gao
Pages: 1980-1988
Published online on: 14 February 2017

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Article Open Access

Chemosensitizing effect of shRNA-mediated ERCC1 silencing on a Xuanwei lung adenocarcinoma cell line and its clinical significance

Weiwei Wang, Lijun Zhang, Liang Liu, Yongfa Zheng, Yong Zhang, Siyuan Yang, Rongliang Shi, Shaojia Wang
Pages: 1989-1997
Published online on: 14 February 2017

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Article Open Access

G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways

Yizhuo Wang, Huijie Xiao, Haitao Wu, Cheng Yao, Hua He, Chang Wang, Wei Li
Pages: 1998-2006
Published online on: 13 March 2017

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Article Open Access

Activation of the CRABPII/RAR pathway by curcumin induces retinoic acid mediated apoptosis in retinoic acid resistant breast cancer cells

Padmamalini Thulasiraman, Galen Garriga, Veena Danthuluri, Daniel J. McAndrews, Imran Q. Mohiuddin
Pages: 2007-2015
Published online on: 08 March 2017

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Article

Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro

Zhang-Feng Zhong, Wen Tan, Ke Tian, Hua Yu, Wen-An Qiang, Yi-Tao Wang
Pages: 2016-2024
Published online on: 10 February 2017

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Article

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity

Masashi Shiiba, Hitomi Yamagami, Ayumi Yamamoto, Yasuyuki Minakawa, Atsushi Okamoto, Atsushi Kasamatsu, Yosuke Sakamoto, Katsuhiro Uzawa, Yuichi Takiguchi, Hideki Tanzawa
Pages: 2025-2032
Published online on: 01 March 2017

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Article

ADAM9 functions as a promoter of gastric cancer growth which is negatively and post-transcriptionally regulated by miR-126

Junqing Wang, Yunyun Zhou, Xiaochun Fei, Xuehua Chen, Jiqi Yan, Bingya Liu, Zhenggang Zhu
Pages: 2033-2040
Published online on: 16 February 2017

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Article

Octreotide inhibits the proliferation of gastric cancer cells through P300-HAT activity and the interaction of ZAC and P300

Liping Wang, Xin Huang, Yurong Chai, Liyang Zou, Matthew Chedrawe, Yi Ding
Pages: 2041-2048
Published online on: 14 February 2017

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Article

Atorvastatin prolongs the lifespan of radiation‑induced reactive oxygen species in PC-3 prostate cancer cells to enhance the cell killing effect

Hao Yu, Shao-Qian Sun, Xiao-Bin Gu, Wen Wang, Xian-Shu Gao
Pages: 2049-2056
Published online on: 14 February 2017

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Article

Dysregulation of TMPRSS3 and TNFRSF11B correlates with tumorigenesis and poor prognosis in patients with breast cancer

Ping Luo, Gaixia Lu, Lin‑Lin Fan, Xiaoming Zhong, Huiqiong Yang, Ruting Xie, Zhongwei Lv, Qian‑Zhou Lv, Da Fu, Li‑Xin Yang, Yushui Ma
Pages: 2057-2062
Published online on: 14 February 2017

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Article

Tumor-penetrating peptide fused to a pro-apoptotic peptide facilitates effective gastric cancer therapy

Ying Huang, Xihan Li, Huizi Sha, Lianru Zhang, Xinyu Bian, Xiao Han, Baorui Liu
Pages: 2063-2070
Published online on: 10 February 2017

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Article

Upregulation of miR-137 reverses sorafenib resistance and cancer-initiating cell phenotypes by degrading ANT2 in hepatocellular carcinoma

Ai-Qing Lu, Bin Lv, Fei Qiu, Xiao-Yun Wang, Xiao-Hua Cao
Pages: 2071-2078
Published online on: 10 March 2017

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Article

A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells

Xiaoli Dai, Jing Liu, Yin Nian, Ming-Hua Qiu, Ying Luo, Jihong Zhang
Pages: 2079-2086
Published online on: 14 February 2017

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Article

Long non-coding RNA MALAT1 interacts with miR-124 and modulates tongue cancer growth by targeting JAG1 Retraction in /10.3892/or.2018.6688

Tong-Han Zhang, Li-Zhong Liang, Xiao-Ling Liu, Ji-Nan Wu, Kui Su, Jue-Yao Chen, Qiao-Yi Zheng, Hong-Zhang Huang, Gui-Qing Liao
Pages: 2087-2094
Published online on: 14 February 2017

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Article

CXCL8 induces epithelial-mesenchymal transition in colon cancer cells via the PI3K/Akt/NF-κB signaling pathway

Tao Shen, Zhibin Yang, Xianshuo Cheng, Youchuan Xiao, Kun Yu, Xinyi Cai, Cuifeng Xia, Yunfeng Li
Pages: 2095-2100
Published online on: 14 February 2017

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Article

Identification of novel cancer fusion genes using chromosome breakpoint screening

Kate Hua, Chin-Hui Lin, Ya-Lun Chen, Chi-Hung Lin, Yueh‑Hsin Ping, Yuh-Shan Jou, Chian-Feng Chen
Pages: 2101-2108
Published online on: 06 March 2017

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Article

Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism

Chao Wang, Huan Wang, Yaqian Zhang, Wei Guo, Cong Long, Jingchao Wang, Limei Liu, Xiaoping Sun
Pages: 2109-2120
Published online on: 02 March 2017

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Article

Cx32 reverses epithelial-mesenchymal transition in doxorubicin-resistant hepatocellular carcinoma

Meiling Yu, Guangshu Han, Benquan Qi, Xiaoxiang Wu
Pages: 2121-2128
Published online on: 17 February 2017

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Article

Overexpression of miR-203 increases the sensitivity of NSCLC A549/H460 cell lines to cisplatin by targeting Dickkopf-1 Retraction in /10.3892/or.2022.8461

Ruirui Cheng, Chunya Lu, Guojun Zhang, Guowei Zhang, Guoqiang Zhao
Pages: 2129-2136
Published online on: 13 March 2017

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Article

High expression of PINK1 promotes proliferation and chemoresistance of NSCLC

Rui Zhang, Jun Gu, Jie Chen, Jun Ni, Jieru Hung, Zhiwen Wang, Xiaochen Zhang, Jian Feng, Lili Ji
Pages: 2137-2146
Published online on: 02 March 2017

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Article

Knockdown of GATAD2A suppresses cell proliferation in thyroid cancer in vitro

Zongping Wang, Jie Kang, Xianzhao Deng, Bomin Guo, Bo Wu, Youben Fan
Pages: 2147-2152
Published online on: 10 February 2017

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Article

Absence of Malat1 does not prevent DEN-induced hepatocarcinoma in mice

Stéphanie Miard, Marie-Josée Girard, Philippe Joubert, Sophie Carter, Amy Gonzales, Huiping Guo, Benjamin Morpurgo, Louise Boivin, Andrei Golovko, Frédéric Picard
Pages: 2153-2160
Published online on: 20 February 2017

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Article

Enhanced expression of PKM2 associates with the biological properties of cancer stem cells from A549 human lung cancer cells

Chang-Ying Guo, Chen Yan, Lan Luo, Shinji Goto, Yoshishige Urata, Jian-Jun Xu, Xiao-Ming Wen, Yu-Kang Kuang, Fang-Fang Tou, Tao-Sheng Li
Pages: 2161-2166
Published online on: 10 February 2017

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Article

High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma

Rong Liang, Yan Lin, Jia-Zhou Ye, Xue-Xin Yan, Zhi-Hui Liu, Yong-Qiang Li, Xiao-Ling Luo, Hai-Hong Ye
Pages: 2167-2176
Published online on: 15 February 2017

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Article

Combined treatment with vitamin C and methotrexate inhibits triple-negative breast cancer cell growth by increasing H2O2 accumulation and activating caspase-3 and p38 pathways

Ching-Wen Wu, Hsiao-Chun Liu, Yung-Luen Yu, Yu-Ting Hung, Chyou-Wei Wei, Giou-Teng Yiang
Pages: 2177-2184
Published online on: 10 February 2017

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Article

MicroRNA-365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Pages: 2185-2192
Published online on: 16 February 2017

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Article

miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1 Corrigendum in /10.3892/or.2019.7057

Yan Li, Lifen Zhao, Nana Li, Yuan Miao, Huimin Zhou, Li Jia
Pages: 2193-2200
Published online on: 17 February 2017

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Article

AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis Corrigendum in /10.3892/or.2017.5482

Yun Jung Choi, Ji Hye Kim, Jin Kyung Rho, Joong Sun Kim, Chang-Min Choi, Woo Sung Kim, Jaekyoung Son, Jae Cheol Lee
Pages: 2201-2208
Published online on: 01 March 2017

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Article

Runx2 downregulation, migration and proliferation inhibition in melanoma cells treated with BEL β-trefoil

Massimiliano Perduca, Luca Dalle Carbonare, Michele Bovi, Giulio Innamorati, Samuele Cheri, Chiara Cavallini, Maria Teresa Scupoli, Antonio Mori, Maria Teresa Valenti
Pages: 2209-2214
Published online on: 06 March 2017

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Article Open Access

TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma Corrigendum in /10.3892/or.2022.8411

Song Ye, Xin-Yi Zhao, Xiao-Ge Hu, Tang Li, Qiu-Ran Xu, Huan-Ming Yang, Dong-Sheng Huang, Liu Yang
Pages: 2215-2226
Published online on: 08 March 2017

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Article

Anti-hepatoma activities of ethyl acetate extract from Ampelopsis sinica root

Jia-Zhi Wang, Bi-Sheng Huang, Yan Cao, Ke-Li Chen, Juan Li
Pages: 2227-2236
Published online on: 13 March 2017

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Article

Paclitaxel induces apoptosis of esophageal squamous cell carcinoma cells by downregulating STAT3 phosphorylation at Ser727

Xiaolong Zhang, Xiaoyi Wu, Fangling Zhang, Shouyong Mo, Yuanyuan Lu, Wei Wei, Xiaoling Chen, Linhua Lan, Bin Lu, Yongzhang Liu
Pages: 2237-2244
Published online on: 13 March 2017

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Article

Knockdown of PARP6 or survivin promotes cell apoptosis and inhibits cell invasion of colorectal adenocarcinoma cells

Haipeng Wang, Shengguo Li, Xishun Luo, Zhike Song, Xiangkai Long, Xijia Zhu
Pages: 2245-2251
Published online on: 14 February 2017

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Article

GSH depletion and consequent AKT inhibition contribute to the Nrf2 knockdown-induced decrease in proliferation in glioblastoma U251 cells

Yue Jia, Han-Dong Wang, Qiang Wang, Hui Ding, He-Ming Wu, Hao Pan
Pages: 2252-2260
Published online on: 20 February 2017

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Article

FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression

Runze Shang, Meng Pu, Yu Li, Desheng Wang
Pages: 2261-2269
Published online on: 22 February 2017

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Article

Increased expression of HOXB9 in hepatocellular carcinoma predicts poor overall survival but a beneficial response to sorafenib

Naokazu Chiba, Yosuke Ozawa, Kosuke Hikita, Masaaki Okihara, Toru Sano, Koichi Tomita, Kiminori Takano, Shigeyuki Kawachi
Pages: 2270-2276
Published online on: 23 February 2017

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Article

Apigenin inhibits proliferation and invasion, and induces apoptosis and cell cycle arrest in human melanoma cells

Guangming Zhao, Xiaodong Han, Wei Cheng, Jing Ni, Yunfei Zhang, Jingrong Lin, Zhiqi Song
Pages: 2277-2285
Published online on: 14 February 2017

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Article

Epigenetic activation of WHSC1 functions as an oncogene and is associated with poor prognosis in cervical cancer

Zhuolian Yin, Yong Sun, Sufang Ge, Juxiang Sun
Pages: 2286-2294
Published online on: 17 February 2017

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Article

pSTAT5 and ERK exhibit different expression in myeloproliferative neoplasms

Ewa Wiśniewska-Chudy, Łukasz Szylberg, Grzegorz Dworacki, Ewa Mizera-Nyczak, Andrzej Marszałek
Pages: 2295-2307
Published online on: 24 February 2017

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Article

Roles of immune inhibitory molecule B7-H4 in cervical cancer

Sai Han, Yi Li, Jingjing Zhang, Lu Liu, Qian Chen, Qiuhong Qian, Shan Li, Youzhong Zhang
Pages: 2308-2316
Published online on: 01 March 2017

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Article

The anti-metastatic effect of baicalein on colorectal cancer

Yuxia Chai, Jizhong Xu, Baojun Yan
Pages: 2317-2323
Published online on: 10 February 2017

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Article

HPV16 oncogenes E6 or/and E7 may influence the methylation status of RASSFIA gene promoter region in cervical cancer cell line HT-3

Fufen Yin, Ning Wang, Shanshan Wang, Fengsheng Yu, Xin Sun, Xiao Yu, Bing Luo, Chengquan Zhao, Yankui Wang
Pages: 2324-2334
Published online on: 17 February 2017

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Article

Foxk2 inhibits non-small cell lung cancer epithelial-mesenchymal transition and proliferation through the repression of different key target genes

Shu Chen, Simin Jiang, Fen Hu, Yongjian Xu, Tao Wang, Qi Mei
Pages: 2335-2347
Published online on: 16 February 2017

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Article

Osthole enhances TRAIL-mediated apoptosis through downregulation of c-FLIP expression in renal carcinoma Caki cells

Kyoung-Jin Min, Min Ae Han, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon
Pages: 2348-2354
Published online on: 06 March 2017

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Article

Identification of the key genes implicated in the transformation of OLP to OSCC using RNA-sequencing

Qiaozhen Yang, Bin Guo, Hongying Sun, Jie Zhang, Shangfeng Liu, Saiyin Hexige, Xuedi Yu, Xiaxia Wang
Pages: 2355-2365
Published online on: 02 March 2017

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Article

Effects of 5-fluorouracil, adriamycin and irinotecan on HSC-39, a human scirrhous gastric cancer cell line

Rie Tamaki, Aya Kanai-Mori, Yuta Morishige, Atsushi Koike, Kazuyoshi Yanagihara, Fumio Amano
Pages: 2366-2374
Published online on: 20 February 2017

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Article

CIRH1A augments the proliferation of RKO colorectal cancer cells

Feng Guo, Jian-Jun Chen, Wei-Jun Tang
Pages: 2375-2381
Published online on: 08 March 2017

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Article

Silencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy

James Griffith, Daniel Andrade, Meghna Mehta, William Berry, Doris M. Benbrook, Natarajan Aravindan, Terence S. Herman, Rajagopal Ramesh, Anupama Munshi
Pages: 2382-2390
Published online on: 28 February 2017

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Article

FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation Corrigendum in /10.3892/or.2020.7842

Ke Xu, Zhenhao Zhang, Hua Pei, Huamin Wang, Liang Li, Qianfeng Xia
Pages: 2391-2397
Published online on: 16 February 2017

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Article

USP39 promotes colorectal cancer growth and metastasis through the Wnt/β-catenin pathway

Xianwen Yuan, Xitai Sun, Xiaolei Shi, Hao Wang, Guoyi Wu, Chunping Jiang, Decai Yu, Weiwei Zhang, Bin Xue, Yitao Ding
Pages: 2398-2404
Published online on: 15 February 2017

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Article

Actin-like protein 6A is a novel prognostic indicator promoting invasion and metastasis in osteosarcoma

Wei Sun, Wanchun Wang, Jian Lei, Hui Li, Yi Wu
Pages: 2405-2417
Published online on: 23 February 2017

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Article

Co-treatment of breast cancer cells with pharmacologic doses of 2-deoxy-D-glucose and metformin: Starving tumors

Ulrike Wokoun, Martin Hellriegel, Günter Emons, Carsten Gründker
Pages: 2418-2424
Published online on: 06 March 2017

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Article

Berberine sensitizes nasopharyngeal carcinoma cells to radiation through inhibition of Sp1 and EMT

Jun Wang, Min Kang, Qin Wen, Yu-Tao Qin, Zhu-Xin Wei, Jing-Jian Xiao, Ren-Sheng Wang
Pages: 2425-2432
Published online on: 13 March 2017

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Melatonin inhibits angiogenesis in SH-SY5Y human neuroblastoma cells by downregulation of VEGF

Alicia González, Alicia González-González, Carolina Alonso-González, Javier Menéndez-Menéndez, Carlos Martínez-Campa, Samuel Cos
Pages: 2433-2440
Published online on: 14 February 2017

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MicroRNA-134 suppresses cell proliferation in gastric cancer cells via targeting of GOLPH3

Yanqi Liu, Yanhong Sun, Aizhen Zhao
Pages: 2441-2448
Published online on: 02 March 2017

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MicroRNA-455-3p functions as a tumor suppressor by targeting eIF4E in prostate cancer

Yongxiang Zhao, Mingyu Yan, Ye Yun, Jianguo Zhang, Ruimin Zhang, Yan Li, Xiangming Wu, Qiang Liu, Wei Miao, Haishan Jiang
Pages: 2449-2458
Published online on: 13 March 2017

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Depletion of TFAP2E attenuates adriamycin-mediated apoptosis in human neuroblastoma cells

Reina Hoshi, Yosuke Watanabe, Yoshiaki Ishizuka, Takayuki Hirano, Eri Nagasaki-Maeoka, Shinsuke Yoshizawa, Shota Uekusa, Hiroyuki Kawashima, Kensuke Ohashi, Kiminobu Sugito, Noboru Fukuda, Hiroki Nagase, Masayoshi Soma, Toshinori Ozaki, Tsugumichi Koshinaga, Kyoko Fujiwara
Pages: 2459-2464
Published online on: 24 February 2017

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Stanniocalcin 1 promotes cell proliferation via cyclin E1/cyclin‑dependent kinase 2 in human prostate carcinoma

Yao Bai, Yichen Xiao, Yuanqing Dai, Xiong Chen, Dongjie Li, Xinji Tan, Xiaobo Zhang
Pages: 2465-2471
Published online on: 13 March 2017

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Tumor-associated macrophages favor C26 murine colon carcinoma cell proliferation in an oxidative stress-dependent manner

Lavinia Luput, Emilia Licarete, Alina Sesarman, Laura Patras, Marius Costel Alupei, Manuela Banciu
Pages: 2472-2480
Published online on: 17 February 2017

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Vinblastine differs from Taxol as it inhibits the malignant phenotypes of NSCLC cells by increasing the phosphorylation of Op18/stathmin

Fang Shen, Dan Long, Ting Yu, Xian Chen, Ying Liao, Yi Wu, Xuechi Lin
Pages: 2481-2489
Published online on: 20 February 2017

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Upregulation of microRNA-125b-5p is involved in the pathogenesis of osteoarthritis by downregulating SYVN1

Feng‑Xiao Ge, Haitao Li, Xin Yin
Pages: 2490-2496
Published online on: 24 February 2017

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Upregulation of p38 pathway accelerates proliferation and migration of MDA-MB-231 breast cancer cells

Hugo W. Huth, Daniel M. Santos, Humberto D. Gravina, Jarbas M. Resende, Alfredo M. Goes, Maria Elena de Lima, Catherine Ropert
Pages: 2497-2505
Published online on: 14 February 2017

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Clinical and molecular assessment of regorafenib monotherapy

Nao Kakizawa, Koichi Suzuki, Taro Fukui, Yuji Takayama, Kosuke Ichida, Yuta Muto, Fumi Hasegawa, Fumiaki Watanabe, Rina Kikugawa, Shingo Tsujinaka, Kazushige Futsuhara, Yasuyuki Miyakura, Hiroshi Noda, Toshiki Rikiyama
Pages: 2506-2512
Published online on: 15 February 2017

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Article

miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway

Jie Xiao, Weifeng Yu, Kongzu Hu, Maoqiang Li, Jianwei Chen, Zhanchun Li
Pages: 2513-2521
Published online on: 02 March 2017

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Correction Open Access

[Corrigendum] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Pages: 2522-2522
Published online on: 15 February 2017

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Journal Cover
April-2026 Volume 55 Issue 4

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells

Natalia Podhorska, Jan Hrabeta, Marie Belhajova, Tomas Eckschlager
Article Number: 79
Published online on: 25 February 2026

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Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer

Alban Piotrowsky, Christian Leischner, Hendrik Schmieder, Katja Detert, Kathrin Schneider, Johanna Schulte, Sabrina Hammerschmidt, Luigi Marongiu, Olga Renner, Markus Burkard, Sascha Venturelli
Article Number: 78
Published online on: 24 February 2026

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Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review)

Zhen Yang, Huajun Liu, Meilin Chen, Liming Zhang, Meiling Gong, Ruilian Yu
Article Number: 77
Published online on: 24 February 2026

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[Retracted] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Article Number: 76
Published online on: 24 February 2026

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NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

Tingyu Zhang, Yue Wang, Jiuna Zhang, Xueshuai Ye, Yanfeng Shen, Zhiwei Zhang
Article Number: 75
Published online on: 18 February 2026

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Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis

Pampana Sandhya Venkata Lakshmi, Jagrati Parashar, Biswajit Biswas, Ramesh Ummanni
Article Number: 74
Published online on: 16 February 2026

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[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9

Zhu Yuan, Andrew J. Sanders, Lin Ye, Yu Wang, Wen G. Jiang
Article Number: 73
Published online on: 16 February 2026

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Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 72
Published online on: 12 February 2026

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Tumor visualization and evaluation of glioblastoma in mice using small animal 9.4T MRI and PET‑CT with high resolution

Shuangyi Li, Wenjiao Gu, Ying Jiang, Ting Liu, Limei Shuai, Yujie Wei, Youming Shi, Havyarimana Juvenal, Zhimin Wang, Yucai Wei, Bofan Wu, Xiaochun Zhou, Yumin Li, Futian Tang
Article Number: 71
Published online on: 12 February 2026

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Expression of Concern Open Access

[Expression of Concern] Interference of STAT 5b expression enhances the chemo‑sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway‑mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Article Number: 70
Published online on: 11 February 2026

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Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling

Kun Li, Jinwei Chen, Zhi Zheng, Yichun Gao, Jiayu Zhang, Wenya Ding, Tongguo Yang, Yuyang Gu, Xuhua Duan, Tiesuo Zhao, Huijie Jia, Pengfei Chen, Jianzhuang Ren
Article Number: 69
Published online on: 11 February 2026

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Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao
Article Number: 68
Published online on: 10 February 2026

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[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Article Number: 67
Published online on: 09 February 2026

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Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held‑Feindt
Article Number: 85
Published online on: 02 March 2026

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[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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