|
1
|
Siegel R, Desantis C and Jemal A:
Colorectal cancer statistics, 2014. CA Cancer J Clin. 64:104–117.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Davies JM and Goldberg RM: First-line
therapeutic strategies in metastatic colorectal cancer. Oncology
(Williston Park). 22:1470–1479. 2008.PubMed/NCBI
|
|
3
|
Lu J, Ye X, Fan F, Xia L, Bhattacharya R,
Bellister S, Tozzi F, Sceusi E, Zhou Y, Tachibana I, et al:
Endothelial cells promote the colorectal cancer stem cell phenotype
through a soluble form of Jagged-1. Cancer Cell. 23:171–185. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Cai C, Ashktorab H, Pang X, Zhao Y, Sha W,
Liu Y and Gu X: MicroRNA-211 expression promotes colorectal cancer
cell growth in vitro and in vivo by targeting tumor suppressor
CHD5. PLoS One. 7:e297502012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Huang S, Wang C, Yi Y, Sun X, Luo M, Zhou
Z, Li J, Cai Y, Jiang X and Ke Y: Krüppel-like factor 9 inhibits
glioma cell proliferation and tumorigenicity via downregulation of
miR-21. Cancer Lett. 356:547–555. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Zhang H, Sun L, Xiao X, Xie R, Liu C, Wang
Y, Wei Y, Zhang H and Liu L: Krüppel-like factor 8 contributes to
hypoxia-induced MDR in gastric cancer cells. Cancer Sci.
105:1109–1115. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Fadous-Khalifé MC, Aloulou N, Jalbout M,
Hadchity J, Aftimos G, Paris F and Hadchity E: Krüppel-like factor
4A new potential biomarker of lung cancer. Mol Clin Oncol. 5:35–40.
2016.PubMed/NCBI
|
|
8
|
Kim SH, Park YY, Cho SN, Margalit O, Wang
D and DuBois RN: Krüppel-like factor 12 promotes colorectal cancer
growth through early growth response protein 1. PLoS One.
11:e01598992016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Brown AR, Van TT, Simmen RC and Simmen FA:
The potential tumor-suppressive role of Krüppel-like factor 9 in
colorectal cancer. Cancer Res. 73(8 Suppl): 1969. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Bieker JJ: Krüppel-like factors: Three
fingers in many pies. J Biol Chem. 276:34355–34358. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Preiss A, Rosenberg UB, Kienlin A, Seifert
E and Jäckle H: Molecular genetics of Krüppel, a gene required for
segmentation of the Drosophila embryo. Nature. 313:27–32. 1985.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Eaton SA, Funnell AP, Sue N, Nicholas H,
Pearson RC and Crossley M: A network of Krüppel-like Factors
(Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo. J
Biol Chem. 283:26937–26947. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Tetreault MP, Yang Y and Katz JP:
Krüppel-like factors in cancer. Nat Rev Cancer. 13:701–713. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Dang DT, Pevsner J and Yang VW: The
biology of the mammalian Krüppel-like family of transcription
factors. Int J Biochem Cell Biol. 32:1103–1121. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Black AR, Black JD and Azizkhan-Clifford
J: Sp1 and Krüppel-like factor family of transcription factors in
cell growth regulation and cancer. J Cell Physiol. 188:143–160.
2001. View
Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kaczynski J, Cook T and Urrutia R: Sp1-
and Krüppel-like transcription factors. Genome Biol. 4:2062003.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
McConnell BB and Yang VW: Mammalian
Krüppel-like factors in health and diseases. Physiol Rev.
90:1337–1381. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wu J and Lingrel JB: KLF2 inhibits Jurkat
T leukemia cell growth via upregulation of cyclin-dependent kinase
inhibitor p21WAF1/CIP1. Oncogene. 23:8088–8096. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Wang N, Miao H, Li YS, Zhang P, Haga JH,
Hu Y, Young A, Yuan S, Nguyen P, Wu CC, et al: Shear stress
regulation of Krüppel-like factor 2 expression is flow
pattern-specific. Biochem Biophys Res Commun. 341:1244–1251. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Banerjee SS, Feinberg MW, Watanabe M, Gray
S, Haspel RL, Denkinger DJ, Kawahara R, Hauner H and Jain MK: The
Krüppel-like factor KLF2 inhibits peroxisome proliferator-activated
receptor-gamma expression and adipogenesis. J Biol Chem.
278:2581–2584. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Nie FQ, Sun M, Yang JS, Xie M, Xu TP, Xia
R, Liu YW, Liu XH, Zhang EB, Lu KH, et al: Long noncoding RNA ANRIL
promotes non-small cell lung cancer cell proliferation and inhibits
apoptosis by silencing KLF2 and P21 expression. Mol Cancer Ther.
14:268–277. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Xu TP, Liu XX, Xia R, Yin L, Kong R, Chen
WM, Huang MD and Shu YQ: SP1-induced upregulation of the long
noncoding RNA TINCR regulates cell proliferation and apoptosis by
affecting KLF2 mRNA stability in gastric cancer. Oncogene.
34:5648–5661. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Uchida D, Onoue T, Begum NM, Kuribayashi
N, Tomizuka Y, Tamatani T, Nagai H and Miyamoto Y: Vesnarinone
downregulates CXCR4 expression via upregulation of Krüppel-like
factor 2 in oral cancer cells. Mol Cancer. 8:622009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Ebert R, Zeck S, Meissner-Weigl J, Klotz
B, Rachner TD, Benad P, Klein-Hitpass L, Rudert M, Hofbauer LC and
Jakob F: Krüppel-like factors KLF2 and 6 and Ki-67 are direct
targets of zoledronic acid in MCF-7 cells. Bone. 50:723–732. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kawanami D, Mahabeleshwar GH, Lin Z,
Atkins GB, Hamik A, Haldar SM, Maemura K, Lamanna JC and Jain MK:
Kruppel-like factor 2 inhibits hypoxia-inducible factor 1alpha
expression and function in the endothelium. J Biol Chem.
284:20522–20530. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Semenza GL: Targeting HIF-1 for cancer
therapy. Nat Rev Cancer. 3:721–732. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Shen G, Li X, Jia YF, Piazza GA and Xi Y:
Hypoxia-regulated microRNAs in human cancer. Acta Pharmacol Sin.
34:336–341. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Tian Q, Xue Y, Zheng W, Sun R, Ji W, Wang
X and An R: Overexpression of hypoxia-inducible factor 1α induces
migration and invasion through Notch signaling. Int J Oncol.
47:728–738. 2015.PubMed/NCBI
|
|
29
|
Cárdeno A, Sánchez-Hidalgo M, Rosillo MA
and Alarcón de la Lastra C: Oleuropein, a secoiridoid derived from
olive tree, inhibits the proliferation of human colorectal cancer
cell through downregulation of HIF-1α. Nutr Cancer. 65:147–156.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Chen J, Ding Z, Peng Y, Pan F, Li J, Zou
L, Zhang Y and Liang H: HIF-1alpha inhibition reverses multidrug
resistance in colon cancer cells via downregulation of
MDR1/P-glycoprotein. PLoS One. 9:920142014.
|
|
31
|
Wang Y and Liu Y, Malek SN, Zheng P and
Liu Y: Targeting HIF1α eliminates cancer stem cells in
hematological malignancies. Cell Stem Cell. 8:399–411. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Meng RD, Shelton CC, Li YM, Qin LX,
Notterman D, Paty PB and Schwartz GK: gamma-Secretase inhibitors
abrogate oxaliplatin-induced activation of the Notch-1 signaling
pathway in colon cancer cells resulting in enhanced
chemosensitivity. Cancer Res. 69:573–582. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Thacker SA, Robinson P, Abel A and Tweardy
DJ: Modulation of the unfolded protein response during hepatocyte
and cardiomyocyte apoptosis in trauma/hemorrhagic shock. Sci Rep.
3:11872013. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Macari ER, Schaeffer EK, West RJ and
Lowrey CH: Simvastatin and t-butylhydroquinone suppress KLF1 and
BCL11A gene expression and additively increase fetal hemoglobin in
primary human erythroid cells. Blood. 121:830–839. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Duhagon MA, Hurt EM, Sotelo-Silveira JR,
Zhang X and Farrar WL: Genomic profiling of tumor initiating
prostatospheres. BMC Genomics. 11:3242010. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wang F, Zhu Y, Huang Y, McAvoy S, Johnson
WB, Cheung TH, Chung TK, Lo KW, Yim SF, Yu MM, et al:
Transcriptional repression of WEE1 by Kruppel-like factor 2 is
involved in DNA damage-induced apoptosis. Oncogene. 24:3875–3885.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Taniguchi H, Jacinto FV, Villanueva A,
Fernandez AF, Yamamoto H, Carmona FJ, Puertas S, Marquez VE,
Shinomura Y, Imai K, et al: Silencing of Kruppel-like factor 2 by
the histone methyltransferase EZH2 in human cancer. Oncogene.
31:1988–1994. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhang J, Zhu L, Fang J, Ge Z and Li X:
LRG1 modulates epithelial-mesenchymal transition and angiogenesis
in colorectal cancer via HIF-1alpha activation. J Exp Clin Cancer
Res. 35:016–0306. 2016. View Article : Google Scholar
|
|
39
|
Huynh N, Beutler JA, Shulkes A, Baldwin GS
and He H: Glaucarubinone inhibits colorectal cancer growth by
suppression of hypoxia-inducible factor 1α and β-catenin via a p-21
activated kinase 1-dependent pathway. Biochim Biophys Acta.
1853:157–165. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Qiang L, Wu T, Zhang HW, Lu N, Hu R, Wang
YJ, Zhao L, Chen FH, Wang XT, You QD, et al: HIF-1α is critical for
hypoxia-mediated maintenance of glioblastoma stem cells by
activating Notch signaling pathway. Cell Death Differ. 19:284–294.
2012. View Article : Google Scholar : PubMed/NCBI
|
