Journal Articles
Article
A sketch of known and novel MYCN-associated miRNA networks in neuroblastoma
Francesca Megiorni, Moreno Colaiacovo, Samantha Cialfi, Heather P. McDowell, Alessandro Guffanti, Simona Camero, Armando Felsani, Paul D. Losty, Barry Pizer, Rajeev Shukla, Carlo Cappelli, Eva Ferrara, Antonio Pizzuti, Anna Moles, Carlo Dominici
Pages: 3-20 Published online on: 06 June 2017
Article
GROα overexpression drives cell migration and invasion in triple negative breast cancer cells
Kruttika Bhat, Marianna Sarkissyan, Yanyuan Wu, Jaydutt V. Vadgama
Pages: 21-30 Published online on: 24 May 2017
Article
Synthetic lethal interaction of CDK inhibition and autophagy inhibition in human solid cancer cell lines
Yoshinari Okada, Shunsuke Kato, Yasuhiro Sakamoto, Takayuki Oishi, Chikashi Ishioka
Pages: 31-42 Published online on: 30 May 2017
Article
TRIM59 facilitates the proliferation of colorectal cancer and promotes metastasis via the PI3K/AKT pathway
Ye Sun, Bing Ji, Yifei Feng, Yue Zhang, Dongjian Ji, Chunyan Zhu, Sen Wang, Chuan Zhang, Dongsheng Zhang, Yueming Sun
Pages: 43-52 Published online on: 22 May 2017
Article
Fisetin inhibits liver cancer growth in a mouse model: Relation to dopamine receptor
Xiang-Feng Liu, Hai-Jiao Long, Xiong-Ying Miao, Guo-Li Liu, Hong-Liang Yao
Pages: 53-62 Published online on: 30 May 2017
Article
Fangchinoline suppresses growth and metastasis of melanoma cells by inhibiting the phosphorylation of FAK Retraction in /10.3892/or.2024.8740
Jie Shi, Bingyu Guo, Qiang Hui, Peng Chang, Kai Tao
Pages: 63-70 Published online on: 30 May 2017
Article
Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection
Elodie Melsens, Elly De Vlieghere, Benedicte Descamps, Christian Vanhove, Olivier De Wever, Wim Ceelen, Piet Pattyn
Pages: 71-81 Published online on: 15 May 2017
Article
MicroRNA-212 inhibits the metastasis of nasopharyngeal carcinoma by targeting SOX4 Retraction in /10.3892/or.2023.8570
Chengyi Jiang, Hongtao Wang, Lei Zhou, Tao Jiang, Yajia Xu, Lin Xia
Pages: 82-88 Published online on: 15 May 2017
Article
Standardization of A375 human melanoma models on chicken embryo chorioallantoic membrane and Balb/c nude mice
Stefana Avram, Dorina‑Elena Coricovac, Ioana Zinuca Pavel, Iulia Pinzaru, Roxana Ghiulai, Flavia Baderca, Codruta Soica, Danina Muntean, Daciana E. Branisteanu, Demetrios A. Spandidos, Aristides M. Tsatsakis, Cristina Adriana Dehelean
Pages: 89-99 Published online on: 22 May 2017
Article
Upregulation of miR-101 enhances the cytotoxic effect of anticancer drugs through inhibition of colon cancer cell proliferation
Le-Gao Chen, Ying-Jie Xia, Ying Cui
Pages: 100-108 Published online on: 24 May 2017
Article
Low expression of PinX1 is associated with malignant behavior in basal-like breast cancer
Yu-Zhen Feng, Qing-Yan Zhang, Mei-Ting Fu, Zhen-Fei Zhang, Min Wei, Jue-Yu Zhou, Rong Shi
Pages: 109-119 Published online on: 02 June 2017
Article
Hypoxia-induced angiopoietin-like protein 4 as a clinical biomarker and treatment target for human prostate cancer
Shinro Hata, Takeo Nomura, Kazunori Iwasaki, Ryuta Sato, Mutsushi Yamasaki, Fuminori Sato, Hiromitsu Mimata
Pages: 120-128 Published online on: 24 May 2017
Article
New bioactive peptide reduces the toxicity of chemotherapy drugs and increases drug sensitivity
Xian Li, Huijun Wu, Xiaohui Ouyang, Bo Zhang, Xiulan Su
Pages: 129-140 Published online on: 26 May 2017
Article
Overexpression of microRNA-133b is associated with the increased survival of patients with hepatocellular carcinoma after curative hepatectomy: Involvement of the EGFR/PI3K/Akt/mTOR signaling pathway
Xuedong Wang, Jianping Zeng, Liang Wang, Xinjing Zhang, Zhiqian Liu, Hongyi Zhang, Jiahong Dong
Pages: 141-150 Published online on: 06 June 2017
Article
MicroRNA-200c regulates cisplatin resistance by targeting ZEB2 in human gastric cancer cells
Tao Jiang, Pengfei Dong, Long Li, Xiao Ma, Pei Xu, He Zhu, Yanqiu Wang, Baotong Yang, Kuangge Liu, Jinwei Liu, Juan Xue, Runzhe Lv, Panke Su, Guoqiang Kong, Yongchao Chang, Chonggao Zhao, Lidong Wang
Pages: 151-158 Published online on: 22 May 2017
Article
Long non-coding RNA XLOC_006390 promotes cervical cancer proliferation and metastasis through the regulation of SET domain containing 8
Xiaotian Luan, Yankui Wang
Pages: 159-166 Published online on: 23 May 2017
Article
miR-130b regulates the proliferation, invasion and apoptosis of glioma cells via targeting of CYLD
Zhi-Qiang Xiao, Teng-Kun Yin, Ya-Xing Li, Jian-He Zhang, Jian-Jun Gu
Pages: 167-174 Published online on: 19 May 2017
Article
miR-455 inhibits cell proliferation and migration via negative regulation of EGFR in human gastric cancer
Tao Ning, Zhijuan Peng, Shuang Li, Yanjun Qu, Haiyang Zhang, Jingjing Duan, Xinyi Wang, Haiou Yang, Rui Liu, Ting Deng, Ming Bai, Yi Wang, Yiran Si, Le Zhang, Xia Wang, Shaohua Ge, Likun Zhou, Guoguang Ying, Yi Ba
Pages: 175-182 Published online on: 22 May 2017
Article
High expression of PIWIL2 promotes tumor cell proliferation, migration and predicts a poor prognosis in glioma
Jinquan Li, Li Xu, Zhen Bao, Peng Xu, Hao Chang, Jingjing Wu, Yuanqi Bei, Liuwan Xia, Peizhang Wu, Gang Cui
Pages: 183-192 Published online on: 17 May 2017
Article
p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2
Liang-Hui Li, Guo-Yang Wu, Yi-Zhuo Lu, Xue-Hua Chen, Bing‑Ya Liu, Min-Hua Zheng, Jian-Chun Cai
Pages: 193-200 Published online on: 16 May 2017
Article
Expression of the EP300, TP53 and BAX genes in colorectal cancer: Correlations with clinicopathological parameters and survival
Anna E. Kowalczyk, Bartlomiej E. Krazinski, Janusz Godlewski, Jolanta Kiewisz, Przemyslaw Kwiatkowski, Agnieszka Sliwinska-Jewsiewicka, Jacek Kiezun, Marian Sulik, Zbigniew Kmiec
Pages: 201-210 Published online on: 01 June 2017
Article
Functional significance of the long non-coding RNA RP11-169D4.1 as a metastasis suppressor in laryngeal squamous cell carcinoma by regulating CDH1
Jing Zhao, Kexing Lv, Zeng-Hong Li, Jianhui Wu, Wei Gao, Thian-Sze Wong, Jie Luo, Hao Qin, Bin Wang, Qingling Fu, Wen-Bin Lei
Pages: 211-220 Published online on: 16 May 2017
Article
NHERF1 inhibits proliferation of triple-negative breast cancer cells by suppressing GPER signaling
Yan Wang, Zhiqiang Peng, Ran Meng, Tao Tao, Qiqi Wang, Chunjuan Zhao, Hua Liu, Ran Song, Junfang Zheng, Qiong Qin, Junqi He
Pages: 221-228 Published online on: 18 May 2017
Article
HDAC6 inhibition suppresses chondrosarcoma by restoring the expression of primary cilia
Wei Xiang, Fengjing Guo, Weiting Cheng, Jiaming Zhang, Junming Huang, Rui Wang, Zhongxi Ma, Kai Xu
Pages: 229-236 Published online on: 02 June 2017
Article
MARK2 inhibits the growth of HeLa cells through AMPK and reverses epithelial-mesenchymal transition
Ge Xu, Yinggang Ge, Xiaohong Tao, Qing Gao, Xiaoyan Liang
Pages: 237-244 Published online on: 30 May 2017
Article
Synergistic role of Cul1 and c-Myc: Prognostic and predictive biomarkers in colorectal cancer
Weimin Wang, Jianliang Deng, Qianqian Wang, Qiang Yao, Wenjiao Chen, Yongfei Tan, Zhijun Ge, Jianwei Zhou, Yan Zhou
Pages: 245-252 Published online on: 25 May 2017
Article
Silencing of type Iγ phosphatidylinositol phosphate kinase suppresses ovarian cancer cell proliferation, migration and invasion Corrigendum in /10.3892/or.2021.7982
Siyu Cao, Chunhua Chen, Junli Xue, Yan Huang, Xiaofeng Yang, Kun Ling
Pages: 253-262 Published online on: 25 May 2017
Article
EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells
Elisabet Cuyàs, Bernardo Queralt, Begoña Martin-Castillo, Joaquim Bosch-Barrera, Javier A. Menendez
Pages: 263-270 Published online on: 30 May 2017
Article
Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cells
Xuewen Liu, Chao Duan, Juanli Ji, Te Zhang, Xiaoning Yuan, Yunfei Zhang, Wenjing Ma, Jingyuan Yang, Linsen Yang, Zhiguo Jiang, Huiliang Yu, Ying Liu
Pages: 271-278 Published online on: 18 May 2017
Article
Genetic testing and counseling of a recipient after bone marrow transplant from a sibling harboring a germline BRCA1 pathogenic mutation
Petra Škerl, Mateja Krajc, Ana Blatnik, Srdjan Novaković
Pages: 279-282 Published online on: 06 June 2017
Article
Loss of CSMD1 expression disrupts mammary duct formation while enhancing proliferation, migration and invasion
Mohamed Kamal, Deborah L. Holliday, Ewan E. Morrison, Valerie Speirs, Carmel Toomes, Sandra M. Bell
Pages: 283-292 Published online on: 22 May 2017
Article
Microarray expression profile of long non-coding RNAs in paclitaxel-resistant human lung adenocarcinoma cells
Xin Tian, Hongyan Zhang, Bijun Zhang, Jianzhu Zhao, Tingting Li, Yanyan Zhao
Pages: 293-300 Published online on: 01 June 2017
Article
MicroRNA-148a suppresses epithelial-mesenchymal transition and invasion of pancreatic cancer cells by targeting Wnt10b and inhibiting the Wnt/β-catenin signaling pathway Retraction in /10.3892/or.2023.8493
Long Peng, Zhanying Liu, Jian Xiao, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Pages: 301-308 Published online on: 06 June 2017
Article
Silencing of BAG3 promotes the sensitivity of ovarian cancer cells to cisplatin via inhibition of autophagy
Shuang Qiu, Liang Sun, Ye Jin, Qi An, Changjiang Weng, Jianhua Zheng
Pages: 309-316 Published online on: 06 June 2017
Article
DOC-2/DAB2 interactive protein regulates proliferation and mobility of nasopharyngeal carcinoma cells by targeting PI3K/Akt pathway
Bin Wang, Qianqian Gu, Jian Li
Pages: 317-324 Published online on: 06 June 2017
Article
Silencing of ATM expression by siRNA technique contributes to glioma stem cell radiosensitivity in vitro and in vivo
Yan Li, Luchun Li, Zhijuan Wu, Lulu Wang, Yongzhong Wu, Dairong Li, Uiwen Ma, Jianghe Shao, Huiqing Yu, Donglin Wang
Pages: 325-335 Published online on: 24 May 2017
Article
HIF-1α inhibits IDH-1 expression in osteosarcoma
Deng-Cheng Liu, Xun Zheng, Yong Zho, Wan-Rong Yi, Zong-Huan Li, Xiang Hu, Ai-Xi Yu
Pages: 336-342 Published online on: 22 May 2017
Article
miR-1247-5p functions as a tumor suppressor in human hepatocellular carcinoma by targeting Wnt3
Yuankui Chu, Weining Fan, Wenwei Guo, Yixin Zhang, Lixin Wang, Le Guo, Xiangguo Duan, Jun Wei, Guangxian Xu
Pages: 343-351 Published online on: 06 June 2017
Article
Overexpression of miR-15b-5p promotes gastric cancer metastasis by regulating PAQR3
Chengcheng Zhao, Yan Li, Gang Chen, Fen Wang, Zhili Shen, Rongping Zhou
Pages: 352-358 Published online on: 26 May 2017
Article
Ginsenoside Rd regulates the Akt/mTOR/p70S6K signaling cascade and suppresses angiogenesis and breast tumor growth
Eryun Zhang, Hailian Shi, Li Yang, Xiaojun Wu, Zhengtao Wang
Pages: 359-367 Published online on: 19 May 2017
Article
miR-204 regulates the biological behavior of breast cancer MCF-7 cells by directly targeting FOXA1
Si-Qiao Shen, Lan-Shan Huang, Xiao-Ling Xiao, Xiao-Fei Zhu, Dan-Dan Xiong, Xue-Mei Cao, Kang-Lai Wei, Gang Chen, Zhen-Bo Feng
Pages: 368-376 Published online on: 16 May 2017
Article
DcR3 promotes hepatoma cell migration by downregulating E-cadherin expression
Hongling Zhang, Xuhong Chen, Dongming Li, Lulu Cui, Xin Li, Xiufeng Ye, Xiaochun Wan
Pages: 377-383 Published online on: 30 May 2017
Article
miR-370 regulates cell proliferation and migration by targeting EGFR in gastric cancer Corrigendum in /10.3892/or.2022.8409
Tao Ning, Haiyang Zhang, Xinyi Wang, Shuang Li, Le Zhang, Ting Deng, Likun Zhou, Rui Liu, Xia Wang, Ming Bai, Shaohua Ge, Hongli Li, Dingzhi Huang, Guoguang Ying, Yi Ba
Pages: 384-392 Published online on: 23 May 2017
Article
miR-30e acts as a tumor suppressor in hepatocellular carcinoma partly via JAK1/STAT3 pathway
Junjie Mao, Xiaojun Hu, Pengfei Pang, Bin Zhou, Dan Li, Hong Shan
Pages: 393-401 Published online on: 30 May 2017
Article
XAF1 expression levels in a non-small cell lung cancer cohort and its potential association with carcinogenesis
Luciene Schluckebier, Veronica Aran, Joyce De Moraes, Heitor Paiva, Cinthya Sternberg, Carlos Gil Ferreira
Pages: 402-410 Published online on: 30 May 2017
Article
Construction of disease-specific transcriptional regulatory networks identifies co-activation of four gene in esophageal squamous cell carcinoma
Yu Zhao, Li Min, Changqin Xu, Linlin Shao, Shuilong Guo, Rui Cheng, Jie Xing, Shengtao Zhu, Shutian Zhang
Pages: 411-417 Published online on: 30 May 2017
Article
Low HtrA1 expression in patients with long‑standing ulcerative colitis and colorectal cancer
Emma Altobelli, Giovanni Latella, Manrico Morroni, Caterina Licini, Giovanni Tossetta, Roberta Mazzucchelli, Valerio F. Profeta, Gino Coletti, Pietro Leocata, Mario Castellucci, Mario Guerrieri, Reimondo Petrocelli, Berardo De Berardis, Marina De Padova, Gabriella Di Leonardo, Antonella Paladini, Filippo Mignosi, Gina Quaglione, Roberto Fagnano, Daniela Marzioni
Pages: 418-426 Published online on: 06 June 2017
Article
Overexpression of the YAP1 oncogene in clear cell renal cell carcinoma is associated with poor outcome
Agnieszka Rybarczyk, Jakub Klacz, Agata Wronska, Marcin Matuszewski, Zbigniew Kmiec, Piotr M. Wierzbicki
Pages: 427-439 Published online on: 15 May 2017
Article
N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma
Kimihiro Nishino, Eiko Yamamoto, Kaoru Niimi, Yoko Sekiya, Yoriko Yamashita, Fumitaka Kikkawa
Pages: 440-448 Published online on: 23 May 2017
Article
Tumor growth limited to subcutaneous site vs tumor growth in pulmonary site exhibit differential effects on systemic immunities
Junko Masuda, Eiji Takayama, Warren Strober, Ayano Satoh, Yuji Morimoto, Yasuko Honjo, Tatsuo Ichinohe, Shin-Ichi Tokuno, Toshiaki Ishizuka, Takahiro Nakata, Akifumi Mizutani, Naoki Umemura, Atsushi Kitani, Ivan J. Fuss, Tsukasa Shigehiro, Harumi Kawaki, Masako Mizuno-kamiya, Nobuo Kondoh, Masaharu Seno
Pages: 449-455 Published online on: 17 May 2017
Article
Resveratrol inactivates PI3K/Akt signaling through upregulating BMP7 in human colon cancer cells
Yu-Hua Zeng, Lin-Yun Zhou, Qian-Zhao Chen, Yang Li, Ying Shao, Wen-Yan Ren, Yun-Peng Liao, Han Wang, Jia-Hui Zhu, Ming Huang, Fang He, Jin Wang, Ke Wu, Bai-Cheng He
Pages: 456-464 Published online on: 23 May 2017
Article
Amplification and the clinical significance of circulating cell-free DNA of PVT1 in breast cancer
Xujing Li, Weijuan Chen, Hui Wang, Qun Wei, Xiaodi Ding, Wentong Li
Pages: 465-471 Published online on: 18 May 2017
Article
The circadian clock gene PER2 plays an important role in tumor suppression through regulating tumor-associated genes in human oral squamous cell carcinoma
Xiaoli Su, Dan Chen, Kai Yang, Qin Zhao, Dan Zhao, Xiaoqiang Lv, Yiran Ao
Pages: 472-480 Published online on: 19 May 2017
Article
KML001 and doxercalciferol induce synergistic antileukemic effect in acute lymphoid leukemia cells
Yang Liu, Dong-Yeop Shin, Somi Oh, Sujong Kim, Youngil Koh, Inho Kim
Pages: 481-487 Published online on: 01 June 2017
Article
The blueberry component pterostilbene has potent anti-myeloma activity in bortezomib-resistant cells
Gege Chen, Zhijian Xu, Gaomei Chang, Jun Hou, Liangning Hu, Yiwen Zhang, Dandan Yu, Bo Li, Shuaikang Chang, Yongsheng Xie, Yong Zhang, Rong Wei, Huiqun Wu, Wenqin Xiao, Xi Sun, Yi Tao, Lu Gao, Bojie Dai, Jumei Shi, Weiliang Zhu
Pages: 488-496 Published online on: 30 May 2017
Article
MicroRNA-497 acts as a tumor suppressor in gastric cancer and is downregulated by DNA methylation
Jichao Liu, Yongshuang Li, Ying Zou, Jiakui Zhang, Jiaxiang An, Jiao Guo, Minghui Ma, Dongqiu Dai
Pages: 497-505 Published online on: 06 June 2017
Article
Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells
Emiko Akashi, Shintaro Fujihara, Asahiro Morishita, Tomoko Tadokoro, Taiga Chiyo, Keiko Fujikawa, Hideki Kobara, Hirohito Mori, Hisakazu Iwama, Keiichi Okano, Yasuyuki Suzuki, Toshiro Niki, Mitsuomi Hirashima, Tsutomu Masaki
Pages: 506-514 Published online on: 01 June 2017
Article
Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening
Shuliang Zhou, Youde Xiao, Yafei Zhuang, Yinyin Liu, Hong Zhao, Hui Yang, Conghua Xie, Fuxiang Zhou, Yunfeng Zhou
Pages: 515-521 Published online on: 06 June 2017
Article
Exosomes derived from hypoxic epithelial ovarian cancer deliver microRNA-940 to induce macrophage M2 polarization
Xin Chen, Xiang Ying, Xinjing Wang, Xiaoli Wu, Qinyi Zhu, Xipeng Wang
Pages: 522-528 Published online on: 06 June 2017
Article
Methylated +322-327 CpG site decreases hOGG1 mRNA expression in non-small cell lung cancer
Yuanyuan Zeng, Jianjie Zhu, Hualong Qin, Dan Shen, Zhe Lei, Wei Li, Zongli Ding, Jian-An Huang, Zeyi Liu
Pages: 529-537 Published online on: 01 June 2017
Article
Coptidis Rhizoma induces intrinsic apoptosis through BAX and BAK activation in human melanoma
Xiaoou Xu, Satoru Yokoyama, Yoshihiro Hayakawa, Ikuo Saiki
Pages: 538-544 Published online on: 26 May 2017
Article
Reciprocal antagonistic regulation of N-myc mRNA by miR‑17 and the neuronal-specific RNA-binding protein HuD
Leleesha Samaraweera, Barbara A. Spengler, Robert A. Ross
Pages: 545-550 Published online on: 24 May 2017
Article
Therapy-relevant aberrant expression of MRP3 and BCRP mRNA in TCC-/SCC-bladder cancer tissue of untreated patients
Mona Rady, Marwa Mostageer, Jan Rohde, Ashraf Zaghloul, Ruth Knüchel-Clarke, Shady Saad, Deena Attia, Laila Mahran, Hilde Spahn-Langguth
Pages: 551-560 Published online on: 02 June 2017
Article
Treatment of colon cancer cells with 5-fluorouracil can improve the effectiveness of RNA-transfected antitumor dendritic cell vaccine
Carolina V. De Almeida, Jofer A. Zamame, Graziela G. Romagnoli, Cecilia P. Rodrigues, Marianna B. Magalhães, Amedeo Amedei, Ramon Kaneno
Pages: 561-568 Published online on: 01 June 2017
Article
3,3'-diindolylmethane downregulates cyclin D1 through triggering endoplasmic reticulum stress in colorectal cancer cells
Xiaobo Zhang, Pakin Sukamporn, Shiqiang Zhang, Kyung-Won Min, Seung Joon Baek
Pages: 569-574 Published online on: 01 June 2017
Article
Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway
Do-Hee Kim, Ji Eun Park, In Gyeong Chae, Geumi Park, Sooyeun Lee, Kyung-Soo Chun
Pages: 575-583 Published online on: 30 May 2017
Article
KLF2 inhibits cell growth via regulating HIF-1α/Notch-1 signal pathway in human colorectal cancer HCT116 cells
Hai-Gang Wang, Bin Cao, Li-Xian Zhang, Nan Song, Hui Li, Wen-Zeng Zhao, Yan-Shu Li, Shun-Mao Ma, Dong-Jian Yin
Pages: 584-590 Published online on: 06 June 2017
Article
Intermittent low dose irradiation enhances the effectiveness of radio- and chemo-therapy for human colorectal adenocarcinoma cell line HT-29
Yang Wang, Yezhou Li, Li Yang, Dexin Yin
Pages: 591-597 Published online on: 30 May 2017
Article
