|
1
|
Trams EG, Lauter CJ, Salem N Jr and Heine
U: Exfoliation of membrane ecto-enzymes in the form of
micro-vesicles. Biochim Biophys Acta. 645:63–70. 1981. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Harding C, Heuser J and Stahl P:
Receptor-mediated endocytosis of transferrin and recycling of the
transferrin receptor in rat reticulocytes. J Cell Biol. 97:329–339.
1983. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Fong MY, Zhou W, Liu L, Alontaga AY,
Chandra M, Ashby J, Chow A, O'Connor ST, Li S, Chin AR, et al:
Breast-cancer-secreted miR-122 reprograms glucose metabolism in
premetastatic niche to promote metastasis. Nat Cell Biol.
17:183–194. 2015. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Peinado H, Aleckovic M, Lavotshkin S,
Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M,
Williams C, García-Santos G, Ghajar CM, et al: Melanoma exosomes
educate bone marrow progenitor cells toward a pro-metastatic
phenotype through MET. Nat Med. 18:883–891. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Li J, Liu K, Liu Y, Xu Y, Zhang F, Yang H,
Liu J, Pan T, Chen J, Wu M, et al: Exosomes mediate the
cell-to-cell transmission of IFN-[alpha]-induced antiviral
activity. Nat Immunol. 14:793–803. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Colombo M, Raposo G and Thery C:
Biogenesis, secretion, and intercellular interactions of exosomes
and other extracellular vesicles. Annu Rev Cell Dev Biol.
30:255–289. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Tkach M and Thery C: Communication by
extracellular vesicles: Where we are and where we need to go. Cell.
164:1226–1232. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Schorey JS and Harding CV: Extracellular
vesicles and infectious diseases: New complexity to an old story. J
Clin Invest. 126:1181–1189. 2016. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhang X, Yuan X, Shi H, Wu L, Qian H and
Xu W: Exosomes in cancer: Small particle, big player. J Hematol
Oncol. 8:832015. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kalluri R: The biology and function of
exosomes in cancer. J Clin Invest. 126:1208–1215. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Williams RL and Urbé S: The emerging shape
of the ESCRT machinery. Nat Rev Mol Cell Biol. 8:355–368. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Trajkovic K, Hsu C, Chiantia S, Rajendran
L, Wenzel D, Wieland F, Schwille P, Brugger B and Simons M:
Ceramide triggers budding of exosome vesicles into multivesicular
endosomes. Science. 319:1244–1247. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Robbins PD and Morelli AE: Regulation of
immune responses by extracellular vesicles. Nat Rev Immunol.
14:195–208. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Baietti MF, Zhang Z, Mortier E, Melchior
A, Degeest G, Geeraerts A, Ivarsson Y, Depoortere F, Coomans C,
Vermeiren E, et al: Syndecan-syntenin-ALIX regulates the biogenesis
of exosomes. Nat Cell Biol. 14:677–685. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Ostrowski M, Carmo NB, Krumeich S, Fanget
I, Raposo G, Savina A, Moita CF, Schauer K, Hume AN, Freitas RP, et
al: Rab27a and Rab27b control different steps of the exosome
secretion pathway. Nat Cell Biol. 12:19–30. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Fader CM, Sánchez DG, Mestre MB and
Colombo MI: TI-VAMP/VAMP7 and VAMP3/cellubrevin: Two v-SNARE
proteins involved in specific steps of the autophagy/multivesicular
body pathways. Biochim Biophys Acta. 1793:1901–1916. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Yu X, Harris SL and Levine AJ: The
regulation of exosome secretion: A novel function of the p53
protein. Cancer Res. 66:4795–4801. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lespagnol A, Duflaut D, Beekman C, Blanc
L, Fiucci G, Marine J-C, Vidal M, Amson R and Telerman A: Exosome
secretion, including the DNA damage-induced p53-dependent secretory
pathway, is severely compromised in TSAP6/Steap3-null mice. Cell
Death Differ. 15:1723–1733. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Wei Y, Wang D, Jin F, Bian Z, Li L, Liang
H, Li M, Shi L, Pan C, Zhu D, et al: Pyruvate kinase type M2
promotes tumour cell exosome release via phosphorylating
synaptosome-associated protein 23. Nat Commun. 8:140412017.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Savina A, Furlán M, Vidal M and Colombo
MI: Exosome release is regulated by a calcium-dependent mechanism
in K562 cells. J Biol Chem. 278:20083–20090. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Parolini I, Federici C, Raggi C, Lugini L,
Palleschi S, De Milito A, Coscia C, Iessi E, Logozzi M, Molinari A,
et al: Microenvironmental pH is a key factor for exosome traffic in
tumor cells. J Biol Chem. 284:34211–34222. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Alvarez-Erviti L, Seow Y, Yin H, Betts C,
Lakhal S and Wood MJ: Delivery of siRNA to the mouse brain by
systemic injection of targeted exosomes. Nat Biotechnol.
29:341–345. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Morelli AE, Larregina AT, Shufesky WJ,
Sullivan ML, Stolz DB, Papworth GD, Zahorchak AF, Logar AJ, Wang Z,
Watkins SC, et al: Endocytosis, intracellular sorting, and
processing of exosomes by dendritic cells. Blood. 104:3257–3266.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Escrevente C, Keller S, Altevogt P and
Costa J: Interaction and uptake of exosomes by ovarian cancer
cells. BMC Cancer. 11:1082011. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Feng D, Zhao WL, Ye YY, Bai X-C, Liu R-Q,
Chang L-F, Zhou Q and Sui S-F: Cellular internalization of exosomes
occurs through phagocytosis. Traffic. 11:675–687. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Fitzner D, Schnaars M, van Rossum D,
Krishnamoorthy G, Dibaj P, Bakhti M, Regen T, Hanisch U-K and
Simons M: Selective transfer of exosomes from oligodendrocytes to
microglia by macropinocytosis. J Cell Sci. 124:447–458. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Glebov OO, Bright NA and Nichols BJ:
Flotillin-1 defines a clathrin-independent endocytic pathway in
mammalian cells. Nat Cell Biol. 8:46–54. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Otto GP and Nichols BJ: The roles of
flotillin microdomains-endocytosis and beyond. J Cell Sci.
124:3933–3940. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Sun H-L, Cui R, Zhou J, Teng K, Hsiao Y-H,
Nakanishi K, Fassan M, Luo Z, Shi G, Tili E, et al: ERK activation
globally downregulates miRNAs through phosphorylating exportin-5.
Cancer Cell. 30:723–736. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kowal J, Tkach M and Thery C: Biogenesis
and secretion of exosomes. Curr Opin Cell Biol. 29:116–125. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Gutiérrez-Vázquez C, Villarroya-Beltri C,
Mittelbrunn M and Sánchez-Madrid F: Transfer of extracellular
vesicles during immune cell-cell interactions. Immunol Rev.
251:125–142. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wood SL, Knowles MA, Thompson D, Selby PJ
and Banks RE: Proteomic studies of urinary biomarkers for prostate,
bladder and kidney cancers. Nat Rev Urol. 10:206–218. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Subra C, Laulagnier K, Perret B and Record
M: Exosome lipidomics unravels lipid sorting at the level of
multivesicular bodies. Biochimie. 89:205–212. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Valadi H, Ekström K, Bossios A, Sjöstrand
M, Lee JJ and Lötvall JO: Exosome-mediated transfer of mRNAs and
microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 9:654–659. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Melo SA, Sugimoto H, O'Connell JT, Kato N,
Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, et
al: Cancer exosomes perform cell-independent microRNA biogenesis
and promote tumorigenesis. Cancer Cell. 26:707–721. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Crescitelli R, Lässer C, Szabó TG, Kittel
A, Eldh M, Dianzani I, Buzás EI and Lötvall J: Distinct RNA
profiles in subpopulations of extracellular vesicles: Apoptotic
bodies, microvesicles and exosomes. J Extracell Vesicles 2:
eCollection. 2013.doi: 10.3402/jev.v2i0.20677. View Article : Google Scholar
|
|
37
|
Le MT, Hamar P, Guo C, Basar E,
Perdigão-Henriques R, Balaj L and Lieberman J: miR-200-containing
extracellular vesicles promote breast cancer cell metastasis. J
Clin Invest. 124:5109–5128. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zomer A, Maynard C, Verweij FJ, Kamermans
A, Schäfer R, Beerling E, Schiffelers RM, de Wit E, Berenguer J,
Ellenbroek SI, et al: In vivo imaging reveals extracellular
vesicle-mediated phenocopying of metastatic behavior. Cell.
161:1046–1057. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Donnarumma E, Fiore D, Nappa M, Roscigno
G, Adamo A, Iaboni M, Russo V, Affinito A, Puoti I, Quintavalle C,
et al: Cancer-associated fibroblasts release exosomal microRNAs
that dictate an aggressive phenotype in breast cancer. Oncotarget.
8:19592–19608. 2017.PubMed/NCBI
|
|
40
|
Luga V, Zhang L, Viloria-Petit AM,
Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M and
Wrana JL: Exosomes mediate stromal mobilization of autocrine
Wnt-PCP signaling in breast cancer cell migration. Cell.
151:1542–1556. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Webber JP, Spary LK, Sanders AJ, Chowdhury
R, Jiang WG, Steadman R, Wymant J, Jones AT, Kynaston H, Mason MD,
et al: Differentiation of tumour-promoting stromal myofibroblasts
by cancer exosomes. Oncogene. 34:290–302. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Hoshino D, Kirkbride KC, Costello K, Clark
ES, Sinha S, Grega-Larson N, Tyska MJ and Weaver AM: Exosome
secretion is enhanced by invadopodia and drives invasive behavior.
Cell Rep. 5:1159–1168. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Lazar I, Clement E, Dauvillier S, Milhas
D, Ducoux-Petit M, LeGonidec S, Moro C, Soldan V, Dalle S, Balor S,
et al: Adipocyte exosomes promote melanoma aggressiveness through
fatty acid oxidation: A novel mechanism linking obesity and cancer.
Cancer Res. 76:4051–4057. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Al-Nedawi K, Meehan B, Micallef J, Lhotak
V, May L, Guha A and Rak J: Intercellular transfer of the oncogenic
receptor EGFRvIII by microvesicles derived from tumour cells. Nat
Cell Biol. 10:619–624. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Hong BS, Cho J-H, Kim H, Choi E-J, Rho S,
Kim J, Kim J, Choi D-S, Kim Y-K, Hwang D, et al: Colorectal cancer
cell-derived microvesicles are enriched in cell cycle-related mRNAs
that promote proliferation of endothelial cells. BMC Genomics.
10:5562009. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Kogure T, Lin WL, Yan IK, Braconi C and
Patel T: Intercellular nanovesicle-mediated microRNA transfer: A
mechanism of environmental modulation of hepatocellular cancer cell
growth. Hepatology. 54:1237–1248. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Zhu W, Huang L, Li Y, Zhang X, Gu J, Yan
Y, Xu X, Wang M, Qian H and Xu W: Exosomes derived from human bone
marrow mesenchymal stem cells promote tumor growth in vivo. Cancer
Lett. 315:28–37. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Xiao H, Lässer C, Shelke GV, Wang J,
Rådinger M, Lunavat TR, Malmhäll C, Lin LH, Li J, Li L, et al: Mast
cell exosomes promote lung adenocarcinoma cell proliferation-role
of KIT-stem cell factor signaling. Cell Commun Signal. 12:642014.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Yeung Au CL, Co NN, Tsuruga T, Yeung TL,
Kwan SY, Leung CS, Li Y, Lu ES, Kwan K, Wong KK, et al: Exosomal
transfer of stroma-derived miR21 confers paclitaxel resistance in
ovarian cancer cells through targeting APAF1. Nat Commun.
7:111502016. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Zhang Z, Li X, Sun W, Yue S, Yang J, Li J,
Ma B, Wang J, Yang X, Pu M, et al: Loss of exosomal miR-320a from
cancer-associated fibroblasts contributes to HCC proliferation and
metastasis. Cancer Lett. 397:33–42. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Roccaro AM, Sacco A, Maiso P, Azab AK, Tai
Y-T, Reagan M, Azab F, Flores LM, Campigotto F, Weller E, et al: BM
mesenchymal stromal cell-derived exosomes facilitate multiple
myeloma progression. J Clin Invest. 123:1542–1555. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Corthals SL, Jongen-Lavrencic M, de Knegt
Y, Peeters JK, Beverloo HB, Lokhorst HM and Sonneveld P:
Micro-RNA-15a and micro-RNA-16 expression and chromosome 13
deletions in multiple myeloma. Leuk Res. 34:677–681. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Skog J, Würdinger T, Van Rijn S, Meijer
DH, Gainche L, Curry WT, Carter BS, Krichevsky AM and Breakefield
XO: Glioblastoma microvesicles transport RNA and proteins that
promote tumour growth and provide diagnostic biomarkers. Nat Cell
Biol. 10:1470–1476. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Taverna S, Flugy A, Saieva L, Kohn EC,
Santoro A, Meraviglia S, De Leo G and Alessandro R: Role of
exosomes released by chronic myelogenous leukemia cells in
angiogenesis. Int J Cancer. 130:2033–2043. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Hood JL, Pan H, Lanza GM and Wickline SA:
Paracrine induction of endothelium by tumor exosomes. Lab Invest.
89:1317–1328. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Millimaggi D, Mari M, D'Ascenzo S, Carosa
E, Jannini EA, Zucker S, Carta G, Pavan A and Dolo V: Tumor
vesicle-associated CD147 modulates the angiogenic capability of
endothelial cells. Neoplasia. 9:349–357. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Wang J, De Veirman K, Faict S, Frassanito
MA, Ribatti D, Vacca A and Menu E: Multiple myeloma exosomes
establish a favourable bone marrow microenvironment with enhanced
angiogenesis and immunosuppression. J Pathol. 239:162–173. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Gopal SK, Greening DW, Hanssen EG, Zhu
H-J, Simpson RJ and Mathias RA: Oncogenic epithelial cell-derived
exosomes containing Rac1 and PAK2 induce angiogenesis in recipient
endothelial cells. Oncotarget. 7:19709–19722. 2016.PubMed/NCBI
|
|
59
|
Vader P, Breakefield XO and Wood MJ:
Extracellular vesicles: Emerging targets for cancer therapy. Trends
Mol Med. 20:385–393. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Kosaka N, Iguchi H, Hagiwara K, Yoshioka
Y, Takeshita F and Ochiya T: Neutral sphingomyelinase 2
(nSMase2)-dependent exosomal transfer of angiogenic microRNAs
regulate cancer cell metastasis. J Biol Chem. 288:10849–10859.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Fan G-C: Hypoxic exosomes promote
angiogenesis. Blood. 124:3669–3670. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Tadokoro H, Umezu T, Ohyashiki K, Hirano T
and Ohyashiki JH: Exosomes derived from hypoxic leukemia cells
enhance tube formation in endothelial cells. J Biol Chem.
288:34343–34351. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Kosaka N: Decoding the secret of cancer by
means of extracellular vesicles. J Clin Med. 5:222016. View Article : Google Scholar :
|
|
64
|
Liang X, Zhang L, Wang S, Han Q and Zhao
RC: Exosomes secreted by mesenchymal stem cells promote endothelial
cell angiogenesis by transferring miR-125a. J Cell Sci.
129:2182–2189. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Andre F, Schartz NE, Movassagh M, Flament
C, Pautier P, Morice P, Pomel C, Lhomme C, Escudier B, Le Chevalier
T, et al: Malignant effusions and immunogenic tumour-derived
exosomes. Lancet. 360:295–305. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Dai S, Wan T, Wang B, Zhou X, Xiu F, Chen
T, Wu Y and Cao X: More efficient induction of HLA-A*
0201-restricted and carcinoembryonic antigen (CEA)-specific CTL
response by immunization with exosomes prepared from heat-stressed
CEA-positive tumor cells. Clin Cancer Res. 11:7554–7563. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Zitvogel L, Regnault A, Lozier A, Wolfers
J, Flament C, Tenza D, Ricciardi-Castagnoli P, Raposo G and
Amigorena S: Eradication of established murine tumors using a novel
cell-free vaccine: Dendritic cell derived exosomes. Nat Med.
4:594–600. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Condamine T and Gabrilovich DI: Molecular
mechanisms regulating myeloid-derived suppressor cell
differentiation and function. Trends Immunol. 32:19–25. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Valenti R, Huber V, Filipazzi P, Pilla L,
Sovena G, Villa A, Corbelli A, Fais S, Parmiani G and Rivoltini L:
Human tumor-released microvesicles promote the differentiation of
myeloid cells with transforming growth factor-β-mediated
suppressive activity on T lymphocytes. Cancer Res. 66:9290–9298.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Yang C, Kim S-H, Bianco NR and Robbins PD:
Tumor-derived exosomes confer antigen-specific immunosuppression in
a murine delayed-type hypersensitivity model. PLoS One.
6:e225172011. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Ye S, Li Z-L, Luo D, Huang B, Chen Y-S,
Zhang X, Cui J, Zeng Y and Li J: Tumor-derived exosomes promote
tumor progression and T-cell dysfunction through the regulation of
enriched exosomal microRNAs in human nasopharyngeal carcinoma.
Oncotarget. 5:5439–5452. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Clayton A, Mitchell JP, Court J, Mason MD
and Tabi Z: Human tumor-derived exosomes selectively impair
lymphocyte responses to interleukin-2. Cancer Res. 67:7458–7466.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Fabbri M, Paone A, Calore F, Galli R,
Gaudio E, Santhanam R, Lovat F, Fadda P, Mao C, Nuovo GJ, et al:
MicroRNAs bind to Toll-like receptors to induce prometastatic
inflammatory response. Proc Natl Acad Sci USA. 109:E2110–E2116.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Clayton A, Mitchell JP, Court J, Linnane
S, Mason MD and Tabi Z: Human tumor-derived exosomes down-modulate
NKG2D expression. J Immunol. 180:7249–7258. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Ying X, Wu Q, Wu X, Zhu Q and Wang X,
Jiang L, Chen X and Wang X: Epithelial ovarian cancer-secreted
exosomal miR-222-3p induces polarization of tumor-associated
macrophages. Oncotarget. 7:43076–43087. 2016.PubMed/NCBI
|
|
76
|
Cai Z, Yang F, Yu L, Yu Z, Jiang L, Wang
Q, Yang Y, Wang L, Cao X and Wang J: Activated T cell exosomes
promote tumor invasion via Fas signaling pathway. J Immunol.
188:5954–5961. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Chen W, Liu X, Lv M, Chen L, Zhao J, Zhong
S, Ji M, Hu Q, Luo Z, Wu J, et al: Exosomes from drug-resistant
breast cancer cells transmit chemoresistance by a horizontal
transfer of microRNAs. PLoS One. 9:e952402014. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Wei Y, Lai X, Yu S, Chen S, Ma Y, Zhang Y,
Li H, Zhu X, Yao L and Zhang J: Exosomal miR-221/222 enhances
tamoxifen resistance in recipient ER-positive breast cancer cells.
Breast Cancer Res Treat. 147:423–431. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Qu L, Ding J, Chen C, Wu Z-J, Liu B, Gao
Y, Chen W, Liu F, Sun W, Li X-F, et al: Exosome-transmitted lncARSR
promotes sunitinib resistance in renal cancer by acting as a
competing endogenous RNA. Cancer Cell. 29:653–668. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Chen Y, Wang L, Zhu Y, Chen Z, Qi X, Jin
L, Jin J, Hua D and Ma X: Breast cancer resistance protein
(BCRP)-containing circulating microvesicles contribute to
chemoresistance in breast cancer. Oncol Lett. 10:3742–3748.
2015.PubMed/NCBI
|
|
81
|
Richards KE, Zeleniak AE, Fishel ML, Wu J,
Littlepage LE and Hill R: Cancer-associated fibroblast exosomes
regulate survival and proliferation of pancreatic cancer cells.
Oncogene. 36:1770–1778. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Boelens MC, Wu TJ, Nabet BY, Xu B, Qiu Y,
Yoon T, Azzam DJ, Victor Twyman-Saint C, Wiemann BZ, Ishwaran H, et
al: Exosome transfer from stromal to breast cancer cells regulates
therapy resistance pathways. Cell. 159:499–513. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Shedden K, Xie XT, Chandaroy P, Chang YT
and Rosania GR: Expulsion of small molecules in vesicles shed by
cancer cells association with gene expression and chemosensitivity
profiles. Cancer Res. 63:4331–4337. 2003.PubMed/NCBI
|
|
84
|
Ciravolo V, Huber V, Ghedini GC,
Venturelli E, Bianchi F, Campiglio M, Morelli D, Villa A, Mina PD,
Menard S, et al: Potential role of HER2-overexpressing exosomes in
countering trastuzumab-based therapy. J Cell Physiol. 227:658–667.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Aga M, Bentz GL, Raffa S, Torrisi MR,
Kondo S, Wakisaka N, Yoshizaki T, Pagano JS and Shackelford J:
Exosomal HIF1α supports invasive potential of nasopharyngeal
carcinoma-associated LMP1-positive exosomes. Oncogene.
33:4613–4622. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
86
|
Costa-Silva B, Aiello NM, Ocean AJ, Singh
S, Zhang H, Thakur BK, Becker A, Hoshino A, Mark MT, Molina H, et
al: Pancreatic cancer exosomes initiate pre-metastatic niche
formation in the liver. Nat Cell Biol. 17:816–826. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Liu Y, Gu Y, Han Y, Zhang Q, Jiang Z,
Zhang X, Huang B, Xu X, Zheng J and Cao X: Tumor exosomal RNAs
promote lung pre-metastatic niche formation by activating alveolar
epithelial TLR3 to recruit neutrophils. Cancer Cell. 30:243–256.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Hoshino A, Costa-Silva B, Shen T-L,
Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di
Giannatale A, Ceder S, et al: Tumour exosome integrins determine
organotropic metastasis. Nature. 527:329–335. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Bliss SA, Sinha G, Sandiford OA, Williams
LM, Engelberth DJ, Guiro K, Isenalumhe LL, Greco SJ, Ayer S, Bryan
M, et al: Mesenchymal stem cell-derived exosomes stimulate cycling
quiescence and early breast cancer dormancy in bone marrow. Cancer
Res. 76:5832–5844. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
90
|
Tominaga N, Kosaka N, Ono M, Katsuda T,
Yoshioka Y, Tamura K, Lötvall J, Nakagama H and Ochiya T: Brain
metastatic cancer cells release microRNA-181c-containing
extracellular vesicles capable of destructing blood-brain barrier.
Nat Commun. 6:67162015. View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Zhang L, Zhang S, Yao J, Lowery FJ, Zhang
Q, Huang W-C, Li P, Li M, Wang X, Zhang C, et al:
Microenvironment-induced PTEN loss by exosomal microRNA primes
brain metastasis outgrowth. Nature. 527:100–104. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Raposo G and Stoorvogel W: Extracellular
vesicles: Exosomes, microvesicles, and friends. J Cell Biol.
200:373–383. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
93
|
Keller S, Ridinger J, Rupp AK, Janssen JW
and Altevogt P: Body fluid derived exosomes as a novel template for
clinical diagnostics. J Transl Med. 9:862011. View Article : Google Scholar : PubMed/NCBI
|
|
94
|
Pisitkun T, Shen R-F and Knepper MA:
Identification and proteomic profiling of exosomes in human urine.
Proc Natl Acad Sci USA. 101:13368–13373. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Gallo A, Tandon M, Alevizos I and Illei
GG: The majority of microRNAs detectable in serum and saliva is
concentrated in exosomes. PLoS One. 7:e306792012. View Article : Google Scholar : PubMed/NCBI
|
|
96
|
Lau C, Kim Y, Chia D, Spielmann N, Eibl G,
Elashoff D, Wei F, Lin Y-L, Moro A, Grogan T, et al: Role of
pancreatic cancer-derived exosomes in salivary biomarker
development. J Biol Chem. 288:26888–26897. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Kosaka N, Yoshioka Y, Fujita Y and Ochiya
T: Versatile roles of extracellular vesicles in cancer. J Clin
Invest. 126:1163–1172. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
98
|
Taylor DD and Gercel-Taylor C: MicroRNA
signatures of tumor-derived exosomes as diagnostic biomarkers of
ovarian cancer. Gynecol Oncol. 110:13–21. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
99
|
Ogata-Kawata H, Izumiya M, Kurioka D,
Honma Y, Yamada Y, Furuta K, Gunji T, Ohta H, Okamoto H, Sonoda H,
et al: Circulating exosomal microRNAs as biomarkers of colon
cancer. PLoS One. 9:e929212014. View Article : Google Scholar : PubMed/NCBI
|
|
100
|
Zhu M, Huang Z, Zhu D, Zhou X, Shan X, Qi
LW, Wu L, Cheng W, Zhu J, Zhang L, et al: A panel of microRNA
signature in serum for colorectal cancer diagnosis. Oncotarget.
8:17081–17091. 2017.PubMed/NCBI
|
|
101
|
Li Q, Shao Y, Zhang X, Zheng T, Miao M,
Qin L, Wang B, Ye G, Xiao B and Guo J: Plasma long noncoding RNA
protected by exosomes as a potential stable biomarker for gastric
cancer. Tumour Biol. 36:2007–2012. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Li Y, Zheng Q, Bao C, Li S, Guo W, Zhao J,
Chen D, Gu J, He X and Huang S: Circular RNA is enriched and stable
in exosomes: A promising biomarker for cancer diagnosis. Cell Res.
25:981–984. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
103
|
Logozzi M, De Milito A, Lugini L, Borghi
M, Calabrò L, Spada M, Perdicchio M, Marino ML, Federici C, Iessi
E, et al: High levels of exosomes expressing CD63 and caveolin-1 in
plasma of melanoma patients. PLoS One. 4:e52192009. View Article : Google Scholar : PubMed/NCBI
|
|
104
|
Melo SA, Luecke LB, Kahlert C, Fernandez
AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari
N, et al: Glypican-1 identifies cancer exosomes and detects early
pancreatic cancer. Nature. 523:177–182. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
105
|
Lea J, Sharma R, Yang F, Zhu H, Ward ES
and Schroit AJ: Detection of phosphatidylserine-positive exosomes
as a diagnostic marker for ovarian malignancies: A proof of concept
study. Oncotarget. 8:14395–14407. 2017.PubMed/NCBI
|
|
106
|
Manier S, Liu CJ, Avet-Loiseau H, Park J,
Shi J, Campigotto F, Salem KZ, Huynh D, Glavey SV, Rivotto B, et
al: Prognostic role of circulating exosomal miRNAs in multiple
myeloma. Blood. 129:2429–2436. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
107
|
Liu Q, Yu Z, Yuan S, Xie W, Li C, Hu Z,
Xiang Y, Wu N, Wu L, Bai L, et al: Circulating exosomal microRNAs
as prognostic biomarkers for non-small-cell lung cancer.
Oncotarget. 8:13048–13058. 2017.PubMed/NCBI
|
|
108
|
Matsumoto Y, Kano M, Akutsu Y, Hanari N,
Hoshino I, Murakami K, Usui A, Suito H, Takahashi M, Otsuka R, et
al: Quantification of plasma exosome is a potential prognostic
marker for esophageal squamous cell carcinoma. Oncol Rep.
36:2535–2543. 2016.PubMed/NCBI
|
|
109
|
Sandfeld-Paulsen B, Aggerholm-Pedersen N,
Baek R, Jakobsen KR, Meldgaard P, Folkersen BH, Rasmussen TR,
Varming K, Jørgensen MM and Sorensen BS: Exosomal proteins as
prognostic biomarkers in non-small cell lung cancer. Mol Oncol.
10:1595–1602. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
110
|
Liu T, Zhang X, Gao S, Jing F, Yang Y, Du
L, Zheng G, Li P, Li C and Wang C: Exosomal long noncoding RNA
CRNDE-h as a novel serum-based biomarker for diagnosis and
prognosis of colorectal cancer. Oncotarget. 7:85551–85563.
2016.PubMed/NCBI
|
|
111
|
Ye SB, Zhang H, Cai TT, Liu Y-N, Ni J-J,
He J, Peng J-Y, Chen Q-Y, Mo H-Y, Cui J, et al: Exosomal miR-24-3p
impedes T-cell function by targeting FGF11 and serves as a
potential prognostic biomarker for nasopharyngeal carcinoma. J
Pathol. 240:329–340. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
112
|
Wu Z, Zeng Q, Cao K and Sun Y: Exosomes:
Small vesicles with big roles in hepatocellular carcinoma.
Oncotarget. 7:60687–60697. 2016.PubMed/NCBI
|
|
113
|
Hegi ME, Diserens A-C, Gorlia T, Hamou
M-F, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W,
Mariani L, et al: MGMT gene silencing and benefit from temozolomide
in glioblastoma. N Engl J Med. 352:997–1003. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
114
|
Shao H, Chung J, Lee K, Balaj L, Min C,
Carter BS, Hochberg FH, Breakefield XO, Lee H and Weissleder R:
Chip-based analysis of exosomal mRNA mediating drug resistance in
glioblastoma. Nat Commun. 6:69992015. View Article : Google Scholar : PubMed/NCBI
|
|
115
|
Wunsch BH, Smith JT, Gifford SM, Wang C,
Brink M, Bruce RL, Austin RH, Stolovitzky G and Astier Y: Nanoscale
lateral displacement arrays for the separation of exosomes and
colloids down to 20 nm. Nat Nanotechnol. 11:936–940. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
116
|
Marleau AM, Chen C-S, Joyce JA and Tullis
RH: Exosome removal as a therapeutic adjuvant in cancer. J Transl
Med. 10:1342012. View Article : Google Scholar : PubMed/NCBI
|
|
117
|
Morse MA, Garst J, Osada T, Khan S,
Hobeika A, Clay TM, Valente N, Shreeniwas R, Sutton M, Delcayre A,
et al: A phase I study of dexosome immunotherapy in patients with
advanced non-small cell lung cancer. J Transl Med. 3:92005.
View Article : Google Scholar : PubMed/NCBI
|
|
118
|
Escudier B, Dorval T, Chaput N, André F,
Caby M-P, Novault S, Flament C, Leboulaire C, Borg C, Amigorena S,
et al: Vaccination of metastatic melanoma patients with autologous
dendritic cell (DC) derived-exosomes: Results of the first phase I
clinical trial. J Transl Med. 3:102005. View Article : Google Scholar : PubMed/NCBI
|
|
119
|
Tian Y, Li S, Song J, Ji T, Zhu M,
Anderson GJ, Wei J and Nie G: A doxorubicin delivery platform using
engineered natural membrane vesicle exosomes for targeted tumor
therapy. Biomaterials. 35:2383–2390. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
120
|
Kim MS, Haney MJ, Zhao Y, Mahajan V,
Deygen I, Klyachko NL, Inskoe E, Piroyan A, Sokolsky M, Okolie O,
et al: Development of exosome-encapsulated paclitaxel to overcome
MDR in cancer cells. Nanomedicine (Lond). 12:655–664. 2016.
View Article : Google Scholar
|
|
121
|
Katakowski M, Buller B, Zheng X, Lu Y,
Rogers T, Osobamiro O, Shu W, Jiang F and Chopp M: Exosomes from
marrow stromal cells expressing miR-146b inhibit glioma growth.
Cancer Lett. 335:201–204. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
122
|
Ono M, Kosaka N, Tominaga N, Yoshioka Y,
Takeshita F, Takahashi R, Yoshida M, Tsuda H, Tamura K and Ochiya
T: Exosomes from bone marrow mesenchymal stem cells contain a
microRNA that promotes dormancy in metastatic breast cancer cells.
Sci Signal. 7:ra632014. View Article : Google Scholar : PubMed/NCBI
|
|
123
|
Pascucci L, Coccè V, Bonomi A, Ami D,
Ceccarelli P, Ciusani E, Viganò L, Locatelli A, Sisto F, Doglia SM,
et al: Paclitaxel is incorporated by mesenchymal stromal cells and
released in exosomes that inhibit in vitro tumor growth: A new
approach for drug delivery. J Control Release. 192:262–270. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
124
|
Wang T, Ning K, Lu TX, Sun X, Jin L, Qi X,
Jin J and Hua D: Increasing circulating exosomes-carrying TRPC5
predicts chemoresistance in metastatic breast cancer patients.
Cancer Sci. 108:448–454. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
125
|
Hannafon BN, Trigoso YD, Calloway CL, Zhao
YD, Lum DH, Welm AL, Zhao ZJ, Blick KE, Dooley WC and Ding WQ:
Plasma exosome microRNAs are indicative of breast cancer. Breast
Cancer Res. 18:902016. View Article : Google Scholar : PubMed/NCBI
|
|
126
|
Liu C, Eng C, Shen J, Lu Y, Takata Y,
Mehdizadeh A, Chang GJ, Rodriguez-Bigas MA, Li Y, Chang P, et al:
Serum exosomal miR-4772-3p is a predictor of tumor recurrence in
stage II and III colon cancer. Oncotarget. 7:76250–76260.
2016.PubMed/NCBI
|
|
127
|
Matsumura T, Sugimachi K, Iinuma H,
Takahashi Y, Kurashige J, Sawada G, Ueda M, Uchi R, Ueo H, Takano
Y, et al: Exosomal microRNA in serum is a novel biomarker of
recurrence in human colorectal cancer. Br J Cancer. 113:275–281.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
128
|
Zhou X, Wen W, Shan X, Zhu W, Xu J, Guo R,
Cheng W, Wang F, Qi LW, Chen Y, et al: A six-microRNA panel in
plasma was identified as a potential biomarker for lung
adenocarcinoma diagnosis. Oncotarget. 8:6513–6525. 2017.PubMed/NCBI
|
|
129
|
Rodríguez M, Silva J, López-Alfonso A,
López-Muñiz MB, Peña C, Domínguez G, García JM, López-Gónzalez A,
Méndez M, Provencio M, et al: Different exosome cargo from
plasma/bronchoalveolar lavage in non-small-cell lung cancer. Genes
Chromosomes Cancer. 53:713–724. 2014.PubMed/NCBI
|
|
130
|
Brinkmann K, Carbone DP, Enderle D,
Koestler T, Bentink S, Emenegger J, Spiel A, Mueller R, O'Neill V,
Skog J, et al: Exosomal RNA based liquid biopsy detection of
EML4-ALK in plasma from NSCLC patients. Proc Int Assoc IALSC
Denver, CO: 2016
|
|
131
|
Madhavan B, Yue S, Galli U, Rana S, Gross
W, Müller M, Giese NA, Kalthoff H, Becker T, Büchler MW, et al:
Combined evaluation of a panel of protein and miRNA serum-exosome
biomarkers for pancreatic cancer diagnosis increases sensitivity
and specificity. Int J Cancer. 136:2616–2627. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
132
|
Işın M, Uysaler E, Özgür E, Köseoğlu H,
Şanlı Ö, Yücel ÖB, Gezer U and Dalay N: Exosomal lncRNA-p21 levels
may help to distinguish prostate cancer from benign disease. Front
Genet. 6:1682015.PubMed/NCBI
|
|
133
|
Huang Z, Zhang L, Zhu D, Shan X, Zhou X,
Qi LW, Wu L, Zhu J, Cheng W, Zhang H, et al: A novel serum microRNA
signature to screen esophageal squamous cell carcinoma. Cancer Med.
6:109–119. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
134
|
Mirzaei H, Fathullahzadeh S, Khanmohammadi
R, Darijani M, Momeni F, Masoudifar A, Goodarzi M, Mardanshah O,
Stanveng J, Jaafari MR, et al: State of the art in microRNA as
diagnostic and therapeutic biomarkers in chronic lymphocytic
leukemia. J Cell Physiol. Jan 13–2017.(Epub ahead of print).
View Article : Google Scholar
|
|
135
|
Sugimachi K, Matsumura T, Hirata H, Uchi
R, Ueda M, Ueo H, Shinden Y, Iguchi T, Eguchi H, Shirabe K, et al:
Identification of a bona fide microRNA biomarker in serum exosomes
that predicts hepatocellular carcinoma recurrence after liver
transplantation. Br J Cancer. 112:532–538. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
136
|
Wang H, Hou L, Li A, Duan Y, Gao H and
Song X: Expression of serum exosomal microRNA-21 in human
hepatocellular carcinoma. Biomed Res Int.
2014:8648942014.PubMed/NCBI
|
|
137
|
Sohn W, Kim J, Kang SH, Yang SR, Cho J-Y,
Cho HC, Shim SG and Paik Y-H: Serum exosomal microRNAs as novel
biomarkers for hepatocellular carcinoma. Exp Mol Med. 47:e1842015.
View Article : Google Scholar : PubMed/NCBI
|
|
138
|
Hong CS, Muller L, Boyiadzis M and
Whiteside TL: Isolation and characterization of CD34 blast-derived
exosomes in acute myeloid leukemia. PLoS One. 9:e1033102014.
View Article : Google Scholar : PubMed/NCBI
|
