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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2017 Volume 38 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Cancer drug delivery in the nano era: An overview and perspectives (Review)

Zhen Li, Shirui Tan, Shuan Li, Qiang Shen, Kunhua Wang
Pages: 611-624
Published online on: 14 June 2017

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Review Open Access

Anti-angiogenesis target therapy for advanced osteosarcoma (Review)

Lu Xie, Tao Ji, Wei Guo
Pages: 625-636
Published online on: 21 June 2017

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Review

Anticancer potential of bioactive peptides from animal sources (Review)

Linghong Wang, Chao Dong, Xian Li, Wenyan Han, Xiulan Su
Pages: 637-651
Published online on: 03 July 2017

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Review

The function of miRNAs in hepatocarcinogenesis induced by hepatitis B virus X protein (Review)

Ziyao Wang, Zhongjun Wu, Ping Huang
Pages: 652-664
Published online on: 13 June 2017

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Review Open Access

Exosomes: New players in cancer (Review)

Wei Guo, Yibo Gao, Ning Li, Fei Shao, Chunni Wang, Pan Wang, Zhenlin Yang, Renda Li, Jie He
Pages: 665-675
Published online on: 13 June 2017

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Review

Progress in mass spectrometry-based proteomic research of tumor hypoxia (Review)

Zhiqi Gao, Gang Luo, Bing Ni
Pages: 676-684
Published online on: 23 June 2017

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Article Open Access

Concomitant Mycobacterium tuberculosis infection promotes lung tumor growth through enhancing Treg development

Yan Zhou, Zhangguo Hu, Shuhui Cao, Bo Yan, Jialin Qian, Hua Zhong
Pages: 685-692
Published online on: 19 June 2017

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Article Open Access

Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells

Nakako Izumi Nakajima, Atsuko Niimi, Mayu Isono, Takahiro Oike, Hiro Sato, Takashi Nakano, Atsushi Shibata
Pages: 693-702
Published online on: 30 June 2017

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Article Open Access

Galangin suppresses human laryngeal carcinoma via modulation of caspase-3 and AKT signaling pathways

Hai-Xu Wang, Chen Tang
Pages: 703-714
Published online on: 29 June 2017

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Article Open Access

Apigenin overcomes drug resistance by blocking the signal transducer and activator of transcription 3 signaling in breast cancer cells

Hye‑Sook Seo, Jin Mo Ku, Hyeong Sim Choi, Jong‑Kyu Woo, Byung Hoon Lee, Doh Sun Kim, Hyun Jong Song, Bo‑Hyoung Jang, Yong Cheol Shin, Seong‑Gyu Ko
Pages: 715-724
Published online on: 26 June 2017

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Article Open Access

miR-543 functions as a tumor suppressor in glioma in vitro and in vivo

Liang Xu, Ju Yu, Zhongyong Wang, Qing Zhu, Wenjie Wang, Qing Lan
Pages: 725-734
Published online on: 12 June 2017

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Article Open Access

Centromere protein U is a potential target for gene therapy of human bladder cancer

Sheng Wang, Beibei Liu, Jiajun Zhang, Wei Sun, Changyuan Dai, Wenyan Sun, Qingwen Li
Pages: 735-744
Published online on: 30 June 2017

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Article Open Access

Suppression of midkine gene promotes the antitumoral effect of cisplatin on human gastric cancer cell line AGS in vitro and in vivo via the modulation of Notch signaling pathway

Wenyan Tian, Jiaqing Shen, Weichang Chen
Pages: 745-754
Published online on: 22 June 2017

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Article Open Access

P18 peptide, a functional fragment of pigment epithelial-derived factor, inhibits angiogenesis in hepatocellular carcinoma via modulating VEGF/VEGFR2 signalling pathway

Xin Wang, Peng Xiu, Fuhai Wang, Jingtao Zhong, Honglong Wei, Zongzhen Xu, Feng Liu, Jie Li
Pages: 755-766
Published online on: 14 June 2017

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Article Open Access

The homologous recombination protein RAD51 is a promising therapeutic target for cervical carcinoma

Qian Chen, Dongge Cai, Mu Li, Xiaoling Wu
Pages: 767-774
Published online on: 15 June 2017

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Article Open Access

Distinctive crypt shape in a sessile serrated adenoma/polyp: Distribution of Ki67-, p16INK4a-, WNT5A-positive cells and intraepithelial lymphocytes

Kenji Hisamatsu, Kei Noguchi, Hiroyuki Tomita, Aoi Muto, Natsumi Yamada, Kazuhiro Kobayashi, Akihiro Hirata, Tomohiro Kanayama, Ayumi Niwa, Kazuhisa Ishida, Takayuki Nakashima, Yuichiro Hatano, Natsuko Suzui, Tatsuhiko Miyazaki, Akira Hara
Pages: 775-784
Published online on: 15 June 2017

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Article Open Access

Glioma cells enhance angiogenesis and inhibit endothelial cell apoptosis through the release of exosomes that contain long non-coding RNA CCAT2

Hai-Li Lang, Guo-Wen Hu, Bo Zhang, Wei Kuang, Yong Chen, Lei Wu, Guo-Hai Xu
Pages: 785-798
Published online on: 22 June 2017

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Article Open Access

Microarray analysis reveals differentially expressed lncRNAs in benign epithelial ovarian cysts and normal ovaries

Xiaoguang Liu, Chencheng Dai, Genmei Jia, Sujuan Xu, Ziyi Fu, Juan Xu, Qing Li, Hongjie Ruan, Pengfei Xu
Pages: 799-808
Published online on: 22 June 2017

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Article Open Access

Construction of a recombinant lentivirus-mediated shRNA expression vector targeting the human PSMD10 gene and validation of RNAi efficiency in RPMI‑8226 multiple myeloma cells

Siyue Du, Wenjiao Qin, Haiyan Leng, Zi Chen, Tao Zhang
Pages: 809-818
Published online on: 30 June 2017

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Article Open Access

Anticancer and apoptosis‑inducing effects of quercetin in vitro and in vivo

Mahmoud Hashemzaei, Amin Delarami Far, Arezoo Yari, Reza Entezari Heravi, Kaveh Tabrizian, Seyed Mohammad Taghdisi, Sarvenaz Ekhtiari Sadegh, Konstantinos Tsarouhas, Dimitrios Kouretas, George Tzanakakis, Dragana Nikitovic, Nikita Yurevich Anisimov, Demetrios   A. Spandidos, Aristides M. Tsatsakis, Ramin Rezaee
Pages: 819-828
Published online on: 28 June 2017

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Article Open Access

Nicotinic acid impairs assembly of leading edge in glioma cells

Xiangcai Yang, Shuting Mei, Hua Niu, Jiejing Li
Pages: 829-836
Published online on: 27 June 2017

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Article Open Access

Tetramethylpyrazine inhibits prostate cancer progression by downregulation of forkhead box M1 Retraction in /10.3892/or.2024.8811

Yi Zhou, Zhigang Ji, Weigang Yan, Zhien Zhou, Hanzhong Li, Yu Xiao
Pages: 837-842
Published online on: 29 June 2017

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Article Open Access

MicroRNA-345 inhibits hepatocellular carcinoma metastasis by inhibiting YAP1 Retraction in /10.3892/or.2025.8913

Hui Zhang, Hui Liu, Huaqiang Bi
Pages: 843-849
Published online on: 30 June 2017

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Article Open Access

Utilization of E-cadherin by monocytes from tumour cells plays key roles in the progression of bone invasion by oral squamous cell carcinoma

Jingjing Quan, Qian Du, Yuluan Hou, Zhiyuan Wang, Jingyuan Zhang
Pages: 850-858
Published online on: 23 June 2017

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Article Open Access

BMH-21 inhibits viability and induces apoptosis by p53-dependent nucleolar stress responses in SKOV3 ovarian cancer cells

Xinxu Fu, Lu Xu, Ling Qi, Hongyan Tian, Dan Yi, Yang Yu, Shibing Liu, Songyan Li, Ye Xu, Chunyan Wang
Pages: 859-865
Published online on: 23 June 2017

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Article Open Access

Overexpression of A disintegrin and metalloprotease 10 promotes tumor proliferation, migration and poor prognosis in hypopharyngeal squamous cell carcinoma

Chuanjin Ding, Qicheng Zhang, Yan Chen, Xiaobo Zhang, Pei Wu, Zhenxin Zhang
Pages: 866-874
Published online on: 27 June 2017

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Article Open Access

Bioinformatic analysis reveals potential properties of human Claudin-6 regulation and functions

Dongjing Lin, Yaxiong Guo, Yanru Li, Yang Ruan, Mingzi Zhang, Xiangshu Jin, Minlan Yang, Yan Lu, Peiye Song, Shuai Zhao, Bing Dong, Yinping Xie, Qihua Dang, Chengshi Quan
Pages: 875-885
Published online on: 27 June 2017

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Article Open Access

Intratumoral and peritumoral expression of CD68 and CD206 in hepatocellular carcinoma and their prognostic value

Chun-Xia Ren, Rui-Xue Leng, Yin-Guang Fan, Hai-Feng Pan, Bao-Zhu Li, Chang-Hao Wu, Qiang Wu, Na-Na Wang, Qi-Ru Xiong, Xiao-Ping Geng, Dong-Qing Ye
Pages: 886-898
Published online on: 21 June 2017

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Article Open Access

Targeting the PD-L1/DNMT1 axis in acquired resistance to sorafenib in human hepatocellular carcinoma

Jianhua Liu, Yahui Liu, Lingyu Meng, Kai Liu, Bai Ji
Pages: 899-907
Published online on: 14 June 2017

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Article

Expression of cell cycle-related proteins in oropharyngeal squamous cell carcinoma based on human papilloma virus status

Koudai Tsuchida, Tamotsu Sugai, Noriyuki Uesugi, Kazuyuki Ishida, Kazuto Matsuura, Ikuro Sato, Kiyoto Shiga, Hiroaki Sato
Pages: 908-916
Published online on: 14 June 2017

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Article

Stromal antigen 2 functions as a tumor suppressor in bladder cancer cells

Han Wang, Jianhua Zhong, Chenglong Wu, Yang Liu, Jinghua Zhang, Xiaowen Zou, Yan Chen, Jinfeng Su, Gang Yang, Yuantang Zhong, Aifa Tang
Pages: 917-925
Published online on: 12 June 2017

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Article

Cetuximab promotes SN38 sensitivity via suppression of heat shock protein 27 in colorectal cancer cells with wild-type RAS

Takashi Ishida, Yoshiyuki Ishii, Masashi Tsuruta, Koji Okabayashi, Shingo Akimoto, Kaoru Koishikawa, Hirotoshi Hasegawa, Yuko Kitagawa
Pages: 926-932
Published online on: 21 June 2017

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Article

Inhibition of Skp2 suppresses the proliferation and invasion of osteosarcoma cells

Lu Ding, Rong Li, Xiaoping Han, Yubo Zhou, Hua Zhang, Yong Cui, Wu Wang, Jingping Bai
Pages: 933-940
Published online on: 12 June 2017

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Article

lncRNA XIST interacts with miR-140 to modulate lung cancer growth by targeting iASPP

Yongjun Tang, Ruoxi He, Jian An, Pengbo Deng, Li Huang, Wei Yang
Pages: 941-948
Published online on: 26 June 2017

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Article

Inactivation of AKT, ERK and NF-κB by genistein derivative, 7-difluoromethoxyl-5,4'-di-n-octylygenistein, reduces ovarian carcinoma oncogenicity

Yingxia Ning, Meng Xu, Xiaocheng Cao, Xiangding Chen, Xin Luo
Pages: 949-958
Published online on: 09 June 2017

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Article

Low expression of microRNA-320b correlates with tumorigenesis and unfavorable prognosis in glioma

Qiao-Li Lv, Hong Du, Yan-Ling Liu, Yuang-Tao Huang, Gui-Hua Wang, Xue Zhang, Shu-Hui Chen, Hong-Hao Zhou
Pages: 959-966
Published online on: 28 June 2017

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Article

Klotho suppresses tumor progression via inhibiting IGF-1R signaling in T‑cell lymphoma

Xiangxiang Zhou, Ya Zhang, Ying Li, Yangyang Xu, Lingyan Zhang, Ying Li, Xin Wang
Pages: 967-974
Published online on: 22 June 2017

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Article

KLF4 inhibits colorectal cancer cell proliferation dependent on NDRG2 signaling

Yongzheng Ma, Lin Wu, Xuewu Liu, Yuqiao Xu, Wei Shi, Ye Liang, Libo Yao, Jianyong Zheng, Jian Zhang
Pages: 975-984
Published online on: 21 June 2017

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Article

Involvement of mitochondrial dynamics in the antineoplastic activity of cisplatin in murine leukemia L1210 cells

Xiao-Jian Han, Sheng-Lan Shi, Yong-Fang Wei, Li-Ping Jiang, Miao-Yu Guo, Hong-Li Wu, Yu-Ying Wan
Pages: 985-992
Published online on: 28 June 2017

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Article

Hypoxia- and acidosis-driven aberrations of secreted microRNAs in endometrial cancer in vitro

Julia Eismann, Marc Hirschfeld, Thalia Erbes, Gerta Rücker, Markus Jäger, Andrea Ritter, Daniela Weiss, Gerald Gitsch, Sebastian Mayer
Pages: 993-1004
Published online on: 13 June 2017

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Article

CIP2A, an oncoprotein, is associated with cell proliferation, invasion and migration in laryngeal carcinoma cells Retraction in /10.3892/or.2025.8875

Xu-Dong Chen, Shi-Xiong Tang, Jian-Hua Zhang, Li-Tao Zhang, Yao-Wen Wang
Pages: 1005-1012
Published online on: 27 June 2017

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Article

Microvesicles released from human embryonic stem cell derived-mesenchymal stem cells inhibit proliferation of leukemia cells

Yuan Ji, Yongbin Ma, Xiang Chen, Xianyan Ji, Jianyi Gao, Lei Zhang, Kai Ye, Fuhao Qiao, Yao Dai, Hui Wang, Xiangmei Wen, Jiang Lin, Jiabo Hu
Pages: 1013-1020
Published online on: 16 June 2017

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Article

Vasohibin-1 inhibits angiogenesis and suppresses tumor growth in renal cell carcinoma

Guangning Zhao, Ren Na, Liming Li, Huiyuan Xiao, Na Ding, Yan Sun, Ruifa Han
Pages: 1021-1028
Published online on: 22 June 2017

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Article

Desipramine induces apoptosis in hepatocellular carcinoma cells

Dong Kwon Yang, Shang-Jin Kim
Pages: 1029-1034
Published online on: 15 June 2017

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Article

Silencing DEK downregulates cervical cancer tumorigenesis and metastasis via the DEK/p-Ser9-GSK-3β/p-Tyr216-GSK-3β/β-catenin axis

Xiaoyang Xu, Lin Zou, Qiuhui Yao, Yanbo Zhang, Li Gan, Liangdan Tang
Pages: 1035-1042
Published online on: 14 June 2017

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Article

B7-H3 promotes the proliferation, migration and invasiveness of cervical cancer cells and is an indicator of poor prognosis

Yi Li, Jingjing Zhang, Sai Han, Qiuhong Qian, Qian Chen, Lu Liu, Youzhong Zhang
Pages: 1043-1050
Published online on: 19 June 2017

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Article

Suppression of gastric cancer by extract from the tuber of amorphophallus konjac via induction of apoptosis and autophagy

Xi Chen, Lin-Qing Yuan, Lin-Jie Li, Yao Lv, Pei-Feng Chen, Lei Pan
Pages: 1051-1058
Published online on: 22 June 2017

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Article

SIRT6 inhibits growth of gastric cancer by inhibiting JAK2/STAT3 pathway

Jianmei Zhou, Ang Wu, Xiaoting Yu, Jianwei Zhu, Hui Dai
Pages: 1059-1066
Published online on: 27 June 2017

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Article

MicroRNA-138 inhibits cell proliferation in hepatocellular carcinoma by targeting Sirt1

Jia Luo, Pan Chen, Wei Xie, Feiyue Wu
Pages: 1067-1074
Published online on: 03 July 2017

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Article

MicroRNA-448 suppresses metastasis of pancreatic ductal adenocarcinoma through targeting JAK1/STAT3 pathway Retraction in /10.3892/or.2022.8424

Dan-Li Yu, Tao Zhang, Kun Wu, Yan Li, Juan Wang, Jun Chen, Xiao-Quan Li, Xing-Guo Peng, Jia-Ning Wang, Li-Guo Tan
Pages: 1075-1082
Published online on: 03 July 2017

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Article

Downregulation of PRRX1 via the p53-dependent signaling pathway predicts poor prognosis in hepatocellular carcinoma

Mingming Fan, Jun Shen, Hu Liu, Zhijian Wen, Jue Yang, Pinghua Yang, Kai Liu, Yanxin Chang, Jicheng Duan, Kai Lu
Pages: 1083-1090
Published online on: 03 July 2017

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Article

Gonadotropins promote human ovarian cancer cell migration and invasion via a cyclooxygenase 2-dependent pathway

Dingqing Feng, Tingting Zhao, Keqin Yan, Haiyan Liang, Jing Liang, Ying Zhou, Weidong Zhao, Bin Ling
Pages: 1091-1098
Published online on: 03 July 2017

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Article

Overexpression of microRNA-495 suppresses the proliferation and invasion and induces the apoptosis of osteosarcoma cells by targeting high-mobility group nucleosome-binding domain 5

Weibo Jiang, Jia Zheng, Tao Yu, Jincheng Wang
Pages: 1099-1107
Published online on: 13 June 2017

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Article

Robust cancer-specific gene expression by a novel cassette with hTERT and CMV promoter elements

Masakiyo Sakaguchi, Takuya Sadahira, Hideo Ueki, Rie Kinoshita, Hitoshi Murata, Ken-Ichi Yamamoto, Junichiro Futami, Yasutomo Nasu, Kazuhiko Ochiai, Hiromi Kumon, Nam-Ho Huh, Masami Watanabe
Pages: 1108-1114
Published online on: 12 June 2017

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Article

PRMT1 expression is elevated in head and neck cancer and inhibition of protein arginine methylation by adenosine dialdehyde or PRMT1 knockdown downregulates proliferation and migration of oral cancer cells

Chun-Yi Chuang, Chien-Ping Chang, Yu-Jen Lee, Wei-Long Lin, Wen-Wei Chang, Jia-Sian Wu, Ya-Wen Cheng, Huei Lee, Chuan Li
Pages: 1115-1123
Published online on: 21 June 2017

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Article

Effect of OATP1B1 genetic polymorphism on the uptake of tamoxifen and its metabolite, endoxifen

Chun-Mei Gao, Zhichen Pu, Chunyuan He, Dahu Liang, Yuanwei Jia, Xiaolong Yuan, Guangji Wang, Haitang Xie
Pages: 1124-1132
Published online on: 16 June 2017

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Article

MicroRNA-31 inhibits tumor invasion and metastasis by targeting RhoA in human gastric cancer

Fulin Ge, Changzheng Wang, Weihua Wang, Wenhui Liu, Benyan Wu
Pages: 1133-1139
Published online on: 27 June 2017

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Article

Long non-coding RNA C5orf66-AS1 is downregulated in pituitary null cell adenomas and is associated with their invasiveness

Guoqiang Yu, Chuzhong Li, Weiyan Xie, Zhuang Wang, Hua Gao, Lihua Cao, Lingtong Hao, Yazhuo Zhang
Pages: 1140-1148
Published online on: 22 June 2017

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Article

Lentivirus‑mediated knockdown of chondroitin polymerizing factor inhibits glioma cell growth in vitro

Yang-Hua Fan, Bing Xiao, Shi-Gang Lv, Min-Hua Ye, Xin-Gen Zhu, Miao-Jing Wu
Pages: 1149-1155
Published online on: 19 June 2017

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Article

miR-30a inhibits glioma progression and stem cell‑like properties by repression of Wnt5a Expression of Concern in /10.3892/or.2025.8983

Yonghong Zhang, Zhi Wu, Lichao Li, Min Xie
Pages: 1156-1162
Published online on: 16 June 2017

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Article

The inhibitory effects of deep-sea water on doxorubicin‑induced epithelial-mesenchymal transition

So-Young Chun, Soyoung Kim, Kyung-Soo Nam
Pages: 1163-1171
Published online on: 16 June 2017

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Anti-proliferation and anti-metastasis effect of barbaloin in non-small cell lung cancer via inactivating p38MAPK/Cdc25B/Hsp27 pathway

Zhang Zhang, Wei Rui, Zi-Chen Wang, Da-Xin Liu, Lin Du
Pages: 1172-1180
Published online on: 27 June 2017

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MicroRNA and target mRNA selection through invasion and cytotoxicity cell modeling and bioinformatics approaches in esophageal squamous cell carcinoma

Mu Lu, Yaqin Song, Wenbo Fu, Yang Liu, Shitao Huai, Xiaobin Cui, Lijuan Pang, Lan Yang, Yutao Wei
Pages: 1181-1189
Published online on: 30 June 2017

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Article

miR-367 promotes tumor growth by inhibiting FBXW7 in NSCLC

Guodong Xiao, Xiao Gao, Xin Sun, Chengcheng Yang, Boxiang Zhang, Ruiying Sun, Guanghong Huang, Xiang Li, Jian Liu, Ning Du, Dapeng Liu, Rui Liang, Hong Ren, Sida Qin
Pages: 1190-1198
Published online on: 27 June 2017

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Article

MAPK and Hippo signaling pathways crosstalk via the RAF-1/MST-2 interaction in malignant melanoma

Ruizheng Feng, Junsheng Gong, Lina Wu, Lei Wang, Baolin Zhang, Gang Liang, Huixia Zheng, Hong Xiao
Pages: 1199-1205
Published online on: 30 June 2017

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Article

Torilis japonica extract fraction compound, EGFR-targeted inhibition of cancer abnormal metastasis in A549 lung cancer cells

Guen Tae Kim, Sang-Yong Kim, Young Min Kim
Pages: 1206-1212
Published online on: 30 June 2017

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Article

Identification and characterization of miR-96, a potential biomarker of NSCLC, through bioinformatic analysis

Tonghui Cai, Jie Long, Hongyan Wang, Wanxia Liu, Yajie Zhang
Pages: 1213-1223
Published online on: 27 June 2017

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Article

Norcantharidin inhibits IL-6-induced epithelial‑mesenchymal transition via the JAK2/STAT3/TWIST signaling pathway in hepatocellular carcinoma cells

Yebo Gao, Weidong Li, Rui Liu, Qiujun Guo, Jie Li, Yanju Bao, Honggang Zheng, Shulong Jiang, Baojin Hua
Pages: 1224-1232
Published online on: 30 June 2017

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Article

Sodium cantharidinate induces HepG2 cell apoptosis through LC3 autophagy pathway

Ran Tao, Wen-Yi Sun, De-Hai Yu, Wei Qiu, Wei-Qun Yan, Yan-Hua Ding, Guang-Yi Wang, Hai-Jun Li
Pages: 1233-1239
Published online on: 03 July 2017

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Article

MicroRNA-342 inhibits the progression of glioma by directly targeting PAK4

Xianghe Lu, Haowen Wang, Zhipeng Su, Lin Cai, Wenfeng Li
Pages: 1240-1250
Published online on: 03 July 2017

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Article

Suppression of SIRT6 by miR-33a facilitates tumor growth of glioma through apoptosis and oxidative stress resistance

Mingze Chang, Lin Qiao, Bin Li, Juanhong Wang, Gejuan Zhang, Wenzhen Shi, Zhiqin Liu, Naibing Gu, Zhengli Di, Xinlai Wang, Ye Tian
Pages: 1251-1258
Published online on: 03 July 2017

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Article

CtBP2 is associated with angiogenesis and regulates the apoptosis of prostate cancer cells

Qiang Xuan, Xiaoge Zhong, Weidong Li, Zengnan Mo, Yuanjie Huang, Yanling Hu
Pages: 1259-1267
Published online on: 28 June 2017

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Article

Salivary miR-93 and miR-200a as post-radiotherapy biomarkers in head and neck squamous cell carcinoma

Thomas Greither, Freya Vorwerk, Matthias Kappler, Matthias Bache, Helge Taubert, Thomas Kuhnt, Jeremias Hey, Alexander W. Eckert
Pages: 1268-1275
Published online on: 28 June 2017

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Article

MicroRNA-605 functions as a tumor suppressor by targeting INPP4B in melanoma

Lan Chen, Yaxuan Cao, Dongyun Rong, Ye Wang, Yu Cao
Pages: 1276-1286
Published online on: 22 June 2017

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Article

WNT10A/β‑catenin pathway in tumorigenesis of papillary thyroid carcinoma

Tianyi Dong, Zhun Zhang, Wenhong Zhou, Xiangyu Zhou, Chong Geng, Lap Kam Chang, Xingsong Tian, Shili Liu
Pages: 1287-1294
Published online on: 03 July 2017

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Article

miR-138 inhibits gastric cancer growth by suppressing SOX4 Retraction in /10.3892/or.2022.8258

Lei Pang, Bai Li, Baisong Zheng, Liang Niu, Liang Ge
Pages: 1295-1302
Published online on: 22 June 2017

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Article

PRMT2β, a C-terminal splice variant of PRMT2, inhibits the growth of breast cancer cells

Jing Zhong, Ya-Jun Chen, Ling Chen, Ying-Ying Shen, Qing-Hai Zhang, Jing Yang, Ren-Xian Cao, Xu-Yu Zu, Ge-Bo Wen
Pages: 1303-1311
Published online on: 03 July 2017

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Article

Matrine inhibits the metastatic properties of human cervical cancer cells via downregulating the p38 signaling pathway

Xiaoling Wu, Jie Zhou, Dongge Cai, Mu Li
Pages: 1312-1320
Published online on: 03 July 2017

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Journal Cover
April-2026 Volume 55 Issue 4

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells

Natalia Podhorska, Jan Hrabeta, Marie Belhajova, Tomas Eckschlager
Article Number: 79
Published online on: 25 February 2026

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Article Open Access

Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer

Alban Piotrowsky, Christian Leischner, Hendrik Schmieder, Katja Detert, Kathrin Schneider, Johanna Schulte, Sabrina Hammerschmidt, Luigi Marongiu, Olga Renner, Markus Burkard, Sascha Venturelli
Article Number: 78
Published online on: 24 February 2026

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Review Open Access

Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review)

Zhen Yang, Huajun Liu, Meilin Chen, Liming Zhang, Meiling Gong, Ruilian Yu
Article Number: 77
Published online on: 24 February 2026

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Retraction Open Access

[Retracted] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Article Number: 76
Published online on: 24 February 2026

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NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

Tingyu Zhang, Yue Wang, Jiuna Zhang, Xueshuai Ye, Yanfeng Shen, Zhiwei Zhang
Article Number: 75
Published online on: 18 February 2026

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Article

Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis

Pampana Sandhya Venkata Lakshmi, Jagrati Parashar, Biswajit Biswas, Ramesh Ummanni
Article Number: 74
Published online on: 16 February 2026

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Retraction Open Access

[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9

Zhu Yuan, Andrew J. Sanders, Lin Ye, Yu Wang, Wen G. Jiang
Article Number: 73
Published online on: 16 February 2026

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Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 72
Published online on: 12 February 2026

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Article Open Access

Tumor visualization and evaluation of glioblastoma in mice using small animal 9.4T MRI and PET‑CT with high resolution

Shuangyi Li, Wenjiao Gu, Ying Jiang, Ting Liu, Limei Shuai, Yujie Wei, Youming Shi, Havyarimana Juvenal, Zhimin Wang, Yucai Wei, Bofan Wu, Xiaochun Zhou, Yumin Li, Futian Tang
Article Number: 71
Published online on: 12 February 2026

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Expression of Concern Open Access

[Expression of Concern] Interference of STAT 5b expression enhances the chemo‑sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway‑mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Article Number: 70
Published online on: 11 February 2026

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Article Open Access

Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling

Kun Li, Jinwei Chen, Zhi Zheng, Yichun Gao, Jiayu Zhang, Wenya Ding, Tongguo Yang, Yuyang Gu, Xuhua Duan, Tiesuo Zhao, Huijie Jia, Pengfei Chen, Jianzhuang Ren
Article Number: 69
Published online on: 11 February 2026

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Article Open Access

Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao
Article Number: 68
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Article Number: 67
Published online on: 09 February 2026

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Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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