1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
2
|
Li Y, Kong D, Wang Z and Sarkar FH:
Regulation of microRNAs by natural agents: An emerging field in
chemoprevention and chemotherapy research. Pharm Res. 27:1027–1041.
2010. View Article : Google Scholar : PubMed/NCBI
|
3
|
Tseng CY, Lin CH, Wu LY, Wang JS, Chung
MC, Chang JF and Chao MW: Potential combinational anti-cancer
therapy in non-small cell lung cancer with traditional chinese
medicine Sun-Bai-Pi extract and cisplatin. PLoS One.
11:e01554692016. View Article : Google Scholar : PubMed/NCBI
|
4
|
Teng ZY, Cheng XL, Cai XT, Yang Y, Sun XY,
Xu JD, Lu WG, Chen J, Hu CP, Zhou Q, et al: Ancient Chinese formula
Qiong-Yu-Gao protects against cisplatin-induced nephrotoxicity
without reducing anti-tumor activity. Sci Rep. 5:155922015.
View Article : Google Scholar : PubMed/NCBI
|
5
|
Lai JP, He XW, Jiang Y and Chen F:
Preparative separation and determination of matrine from the
Chinese medicinal plant Sophora flavescens Ait by
molecularly imprinted solid-phase extraction. Anal Bioanal Chem.
375:264–269. 2003. View Article : Google Scholar : PubMed/NCBI
|
6
|
Zhang YB, Zhan LQ, Li GQ, Wang F, Wang Y,
Li YL, Ye WC and Wang GC: Dimeric matrine-type alkaloids from the
roots of Sophora flavescens and their anti-hepatitis B virus
activities. J Org Chem. 81:6273–6280. 2016. View Article : Google Scholar : PubMed/NCBI
|
7
|
Gong SS, Li YX, Zhang MT, Du J, Ma PS, Yao
WX, Zhou R, Niu Y, Sun T and Yu JQ: Neuroprotective effect of
matrine in mouse model of vincristine-induced neuropathic pain.
Neurochem Res. 41:3147–3159. 2016. View Article : Google Scholar : PubMed/NCBI
|
8
|
Wu G, Zhou W, Zhao J, Pan X, Sun Y, Xu H,
Shi P, Geng C, Gao L and Tian X: Matrine alleviates
lipopolysaccharide-induced intestinal inflammation and oxidative
stress via CCR7 signal. Oncotarget. 8:11621–11628. 2017.PubMed/NCBI
|
9
|
Kan QC, Zhang HJ, Zhang Y, Li X, Xu YM,
Thome R, Zhang ML, Liu N, Chu YJ, Zhang GX, et al: Matrine
treatment blocks NogoA-induced neural inhibitory signaling pathway
in ongoing experimental autoimmune encephalomyelitis. Mol
Neurobiol. Dec 9–2016.doi.org/10.1007/s12035-016-0333-1. View Article : Google Scholar
|
10
|
Dai ZJ, Gao J, Ji ZZ, Wang XJ, Ren HT, Liu
XX, Wu WY, Kang HF and Guan HT: Matrine induces apoptosis in
gastric carcinoma cells via alteration of Fas/FasL and activation
of caspase-3. J Ethnopharmacol. 123:91–96. 2009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Li L, Xue T, Xu W and Zhou B: Effect of
matrine combined with cisplatin on the expression of XIAP in human
rhabdomyosarcoma RD cells. Oncol Lett. 12:3793–3798.
2016.PubMed/NCBI
|
12
|
Wu J, Hu G, Dong Y, Ma R, Yu Z, Jiang S,
Han Y, Yu K and Zhang S: Matrine induces Akt/mTOR signalling
inhibition-mediated autophagy and apoptosis in acute myeloid
leukaemia cells. J Cell Mol Med. 21:1171–1181. 2016. View Article : Google Scholar : PubMed/NCBI
|
13
|
Ma K, Huang MY, Guo YX and Hu GQ:
Matrine-induced autophagy counteracts cell apoptosis via the ERK
signaling pathway in osteosarcoma cells. Oncol Lett. 12:1854–1860.
2016.PubMed/NCBI
|
14
|
Huang H, Du T, Xu G, Lai Y, Fan X, Chen X,
Li W, Yue F, Li Q, Liu L, et al: Matrine suppresses invasion of
castration-resistant prostate cancer cells by downregulating
MMP-2/9 via NF-kappaB signaling pathway. Int J Oncol. 50:640–648.
2016.PubMed/NCBI
|
15
|
Li LQ, Li XL, Wang L, Du WJ, Guo R, Liang
HH, Liu X, Liang DS, Lu YJ, Shan HL, et al: Matrine inhibits breast
cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells. Cell
Physiol Biochem. 30:631–641. 2012. View Article : Google Scholar : PubMed/NCBI
|
16
|
Wu L, Wang G, Wei J, Huang N, Zhang S,
Yang F, Li M, Zhou G and Wang L: Matrine derivative YF-18 inhibits
lung cancer cell proliferation and migration through
down-regulating Skp2. Oncotarget. 8:11729–11738. 2017.PubMed/NCBI
|
17
|
Ma L, Zhu Z, Jiang L, Sun X, Lu X, Zhou M,
Qian S and Jianyong L: Matrine suppresses cell growth of human
chronic myeloid leukemia cells via its inhibition of the
interleukin-6/Janus activated kinase/signal transducer and
activator of transcription 3 signaling cohort. Leuk Lymphoma.
56:2923–2930. 2015. View Article : Google Scholar : PubMed/NCBI
|
18
|
Huang J and Xu H: Matrine: Bioactivities
and structural modifications. Curr Top Med Chem. 16:3365–3378.
2016. View Article : Google Scholar : PubMed/NCBI
|
19
|
Yong J, Wu X and Lu C: Anticancer advances
of matrine and its derivatives. Curr Pharm Des. 21:3673–3680. 2015.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Liotta LA, Tryggvason K, Garbisa S, Hart
I, Foltz CM and Shafie S: Metastatic potential correlates with
enzymatic degradation of basement membrane collagen. Nature.
284:67–68. 1980. View
Article : Google Scholar : PubMed/NCBI
|
21
|
Osman B, Akool S, Doller A, Müller R,
Pfeilschifter J and Eberhardt W: Differential modulation of the
cytokine-induced MMP-9/TIMP-1 protease-antiprotease system by the
mTOR inhibitor rapamycin. Biochem Pharmacol. 81:134–143. 2011.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Kim JH, Kim JH, Kim SC, Yi YS, Yang WS,
Yang Y, Kim HG, Lee JY, Kim KH, Yoo BC, et al: Adenosine dialdehyde
suppresses MMP-9-mediated invasion of cancer cells by blocking the
Ras/Raf-1/ERK/AP-1 signaling pathway. Biochem Pharmacol.
86:1285–1300. 2013. View Article : Google Scholar : PubMed/NCBI
|
23
|
Chang WL, Yu CC, Chen CS and Guh JH:
Tubulin-binding agents down-regulate matrix metalloproteinase-2 and
−9 in human hormone-refractory prostate cancer cells - a critical
role of Cdk1 in mitotic entry. Biochem Pharmacol. 94:12–21. 2015.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Kim EK and Choi EJ: Compromised MAPK
signaling in human diseases: An update. Arch Toxicol. 89:867–882.
2015. View Article : Google Scholar : PubMed/NCBI
|
25
|
Yang M and Huang CZ: Mitogen-activated
protein kinase signaling pathway and invasion and metastasis of
gastric cancer. World J Gastroenterol. 21:11673–11679. 2015.
View Article : Google Scholar : PubMed/NCBI
|
26
|
Wang XF, Zhou QM, Lu YY, Zhang H, Huang S
and Su SB: Glycyrrhetinic acid potently suppresses breast cancer
invasion and metastasis by impairing the p38 MAPK-AP1 signaling
axis. Expert Opin Ther Targets. 19:577–587. 2015. View Article : Google Scholar : PubMed/NCBI
|
27
|
Muranen T, Selfors LM, Hwang J, Gallegos
LL, Coloff JL, Thoreen CC, Kang SA, Sabatini DM, Mills GB and
Brugge JS: ERK and p38 MAPK activities determine sensitivity to
PI3K/mTOR inhibition via regulation of MYC and YAP. Cancer Res.
76:7168–7180. 2016. View Article : Google Scholar : PubMed/NCBI
|
28
|
Kamel WA, Sugihara E, Nobusue H,
Yamaguchi-Iwai S, Onishi N, Maki K, Fukuchi Y, Matsuo K, Muto A,
Saya H, et al: Simvastatin-induced apoptosis in osteosarcoma cells:
A key role of RhoA-AMPK/p38 MAPK signaling in antitumor activity.
Mol Cancer Ther. 16:182–192. 2017. View Article : Google Scholar : PubMed/NCBI
|
29
|
del Barco Barrantes I and Nebreda AR:
Roles of p38 MAPKs in invasion and metastasis. Biochem Soc Trans.
40:79–84. 2012. View Article : Google Scholar : PubMed/NCBI
|
30
|
Kumar V, Behera R, Lohite K, Karnik S and
Kundu GC: p38 kinase is crucial for osteopontin-induced furin
expression that supports cervical cancer progression. Cancer Res.
70:10381–10391. 2010. View Article : Google Scholar : PubMed/NCBI
|
31
|
Chou RH, Hsieh SC, Yu YL, Huang MH, Huang
YC and Hsieh YH: Fisetin inhibits migration and invasion of human
cervical cancer cells by down-regulating urokinase plasminogen
activator expression through suppressing the p38 MAPK-dependent
NF-κB signaling pathway. PLoS One. 8:e719832013. View Article : Google Scholar : PubMed/NCBI
|
32
|
Feng M, Wang Y, Chen K, Bian Z, Jinfang Wu
and Gao Q: IL-17A promotes the migration and invasiveness of
cervical cancer cells by coordinately activating MMPs expression
via the p38/NF-κB signal pathway. PLoS One. 9:e1085022014.
View Article : Google Scholar : PubMed/NCBI
|
33
|
Zhang L, Wang T, Wen X, Wei Y, Peng X, Li
H and Wei L: Effect of matrine on HeLa cell adhesion and migration.
Eur J Pharmacol. 563:69–76. 2007. View Article : Google Scholar : PubMed/NCBI
|
34
|
Tan C, Qian X, Jia R, Wu M and Liang Z:
Matrine induction of reactive oxygen species activates p38 leading
to caspase-dependent cell apoptosis in non-small cell lung cancer
cells. Oncol Rep. 30:2529–2535. 2013.PubMed/NCBI
|
35
|
Yuan X, Yu L, Li J, Xie G, Rong T, Zhang
L, Chen J, Meng Q, Irving AT, Wang D, et al: ATF3 suppresses
metastasis of bladder cancer by regulating gelsolin-mediated
remodeling of the actin cytoskeleton. Cancer Res. 73:3625–3637.
2013. View Article : Google Scholar : PubMed/NCBI
|
36
|
Yang N, Han F, Cui H, Huang J, Wang T,
Zhou Y and Zhou J: Matrine suppresses proliferation and induces
apoptosis in human cholangiocarcinoma cells through suppression of
JAK2/STAT3 signaling. Pharmacol Rep. 67:388–393. 2015. View Article : Google Scholar : PubMed/NCBI
|
37
|
Xu GP, Zhao W, Zhuang JP, Zu JN, Wang DY,
Han F, Zhang ZP and Yan JL: Matrine inhibits the growth and induces
apoptosis of osteosarcoma cells in vitro by inactivating the Akt
pathway. Tumour Biol. 36:1653–1659. 2015. View Article : Google Scholar : PubMed/NCBI
|
38
|
Thakur V and Bedogni B: The membrane
tethered matrix metalloproteinase MT1-MMP at the forefront of
melanoma cell invasion and metastasis. Pharmacol Res. 111:17–22.
2016. View Article : Google Scholar : PubMed/NCBI
|
39
|
Yan L, Liu X, Yin A, Wei Y, Yang Q and
Kong B: Huaier aqueous extract inhibits cervical cancer cell
proliferation via JNK/p38 pathway. Int J Oncol. 47:1054–1060.
2015.PubMed/NCBI
|
40
|
Li M, Su BS, Chang LH, Gao Q, Chen KL, An
P, Huang C, Yang J and Li ZF: Oxymatrine induces apoptosis in human
cervical cancer cells through guanine nucleotide depletion.
Anticancer Drugs. 25:161–173. 2014. View Article : Google Scholar : PubMed/NCBI
|
41
|
Gogoi B, Gogoi D, Silla Y, Kakoti BB and
Bhau BS: Network pharmacology-based virtual screening of natural
products from Clerodendrum species for identification of novel
anti-cancer therapeutics. Mol Biosyst. 13:406–416. 2017. View Article : Google Scholar : PubMed/NCBI
|
42
|
Wang X, Xu L, Lao Y, Zhang H and Xu H:
Natural products targeting EGFR signaling pathways as potential
anticancer drugs. Curr Protein Pept Sci. Jan 5–2017.(Epub ahead of
print).
|
43
|
Liu Y, Xu Y, Ji W, Li X, Sun B, Gao Q and
Su C: Anti-tumor activities of matrine and oxymatrine: literature
review. Tumour Biol. 35:5111–5119. 2014. View Article : Google Scholar : PubMed/NCBI
|
44
|
Zhang S, Qi J, Sun L, Cheng B, Pan S, Zhou
M and Sun X: Matrine induces programmed cell death and regulates
expression of relevant genes based on PCR array analysis in C6
glioma cells. Mol Biol Rep. 36:791–799. 2009. View Article : Google Scholar : PubMed/NCBI
|
45
|
Yeung KT and Yang J:
Epithelial-mesenchymal transition in tumor metastasis. Mol Oncol.
11:28–39. 2017. View Article : Google Scholar : PubMed/NCBI
|
46
|
Lobb RJ, Lima LG and Möller A: Exosomes:
Key mediators of metastasis and pre-metastatic niche formation.
Semin Cell Dev Biol. Jan 8–2017.doi: 10.1016/j.semcdb.2017.01.004.
View Article : Google Scholar : PubMed/NCBI
|
47
|
Ren H, Zhang S, Ma H, Wang Y, Liu D, Wang
X and Wang Z: Matrine reduces the proliferation and invasion of
colorectal cancer cells via reducing the activity of p38 signaling
pathway. Acta Biochim Biophys Sin (Shanghai). 46:1049–1055. 2014.
View Article : Google Scholar : PubMed/NCBI
|
48
|
Martinelli E, Morgillo F, Troiani T and
Ciardiello F: Cancer resistance to therapies against the
EGFR-RAS-RAF pathway: The role of MEK. Cancer Treat Rev. 53:61–69.
2017. View Article : Google Scholar : PubMed/NCBI
|
49
|
Das AM, Pescatori M, Vermeulen CE, Rens
JA, Seynhaeve AL, Koning GA, Eggermont AM and Ten Hagen TL:
Melanomas prevent endothelial cell death under restrictive culture
conditions by signaling through AKT and p38 MAPK/ERK-1/2 cascades.
Oncoimmunology. 5:e12198262016. View Article : Google Scholar : PubMed/NCBI
|
50
|
Zou X and Blank M: Targeting p38 MAP
kinase signaling in cancer through post-translational
modifications. Cancer Lett. 384:19–26. 2017. View Article : Google Scholar : PubMed/NCBI
|
51
|
Li D, Chen J, Ye J, Zhai X, Song J, Jiang
C, Wang J, Zhang H, Jia X and Zhu F: Anti-inflammatory effect of
the six compounds isolated from Nauclea officinalis Pierrc ex
Pitard, and molecular mechanism of strictosamide via
suppressing the NF-kappaB and MAPK signaling pathway in LPS-induced
RAW 264.7 macrophages. J Ethnopharmacol. 196:66–74. 2016.
View Article : Google Scholar : PubMed/NCBI
|
52
|
Lei YC, Lu CL, Chen L, Ge K, Yang LL, Li W
and Wu YH: C5a/C5aR pathway is essential for up-regulating SphK1
expression through p38-MAPK activation in acute liver failure.
World J Gastroenterol. 22:10148–10157. 2016. View Article : Google Scholar : PubMed/NCBI
|
53
|
Lei H, Li X, Jing B, Xu H and Wu Y: Human
S100A7 induces mature interleukin1α expression by RAGE-p38
MAPK-calpain1 pathway in psoriasis. PLoS One. 12:e01697882017.
View Article : Google Scholar : PubMed/NCBI
|
54
|
Liu Y, Zheng J, Zhang Y, Wang Z, Yang Y,
Bai M and Dai Y: Fucoxanthin activates apoptosis via inhibition of
PI3K/Akt/mTOR pathway and suppresses invasion and migration by
restriction of p38-MMP-2/9 pathway in human glioblastoma cells.
Neurochem Res. 41:2728–2751. 2016. View Article : Google Scholar : PubMed/NCBI
|
55
|
Yu P, Liu Q, Liu K, Yagasaki K, Wu E and
Zhang G: Matrine suppresses breast cancer cell proliferation and
invasion via VEGF-Akt-NF-kappaB signaling. Cytotechnology.
59:219–229. 2009. View Article : Google Scholar : PubMed/NCBI
|
56
|
Kwon CH, Moon HJ, Park HJ, Choi JH and
Park DY: S100A8 and S100A9 promotes invasion and migration through
p38 mitogen-activated protein kinase-dependent NF-κB activation in
gastric cancer cells. Mol Cells. 35:226–234. 2013. View Article : Google Scholar : PubMed/NCBI
|