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Article

Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma

  • Authors:
    • Guohui Qin
    • Jingyao Lian
    • Dongli Yue
    • Xinfeng Chen
    • Shufeng Nan
    • Yu Qi
    • Bing Li
    • Guanghui Cui
    • Xiangnan Li
    • Song Zhao
    • Yi Zhang
  • View Affiliations / Copyright

    Affiliations: Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, Erqi, Zhengzhou, Henan 450052, P.R. China, Department of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, Erqi, Zhengzhou, Henan 450052, P.R. China
  • Pages: 1724-1732
    |
    Published online on: July 12, 2017
       https://doi.org/10.3892/or.2017.5809
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Abstract

Esophageal cancer ranks as the sixth leading cause of cancer-related deaths worldwide. Cancer stemness is mainly considered to be the key factor for cancer recurrence particularly in esophageal cancer. It is important to identify cancer stem cell markers as targets in future therapies. The present study aimed to investigate the expression of putative cancer stem cell-related marker musashi1 (Msi1) and assess the correlation with clinicopathologcal status of esophageal squamous cell carcinoma (ESCC) cases. We then clarified the role of Msi1 in esophageal cancer cells during proliferation, apoptosis, sphere formation and migration. Finally, we investigated the relationship of Msi1 with the prognosis of ESCC patients. ESCC tissue samples from 93 patients and 20 paired histologically normal tissues were procured for immunohistochemical analysis. We analyzed the characteristics of Msi1, using sphere formation and anchorage independent growth. Moreover, using flow cytometry and Cell Counting Kit-8 (CCK-8) assay, we investigated the role of Msi1 in cancer cell proliferation and apoptosis. Furthermore, we clarified the role of Msi1 in the process of sphere formation and migration of ESCC cells through knockdown of Msi1 expression by siRNA in ESCC cell lines. The results revealed that there was a higher expression of Msi1 in ESCC specimens compared with normal tissues. In addition, Msi1 expression was significantly associated with clinical stage and lymph node metastasis. Most importantly, the increased immunocytochemical staining of Msi1 in spheroid cells revealed the stemness characteristics of Msi1 in ESCC. In addition, we found that silencing of Msi1 decreased cell proliferation, migration and induced apoptosis in TE-7 and KYSE70 cells. Furthermore, downregulation of Msi1 attenuated the sphere formation ability of ESCC cells. Patients with higher expression of Msi1 had a shorter survival. In conclusion, Msi1 acts as a stemness-associated gene in esophageal cancer cell lines and could serve as a prognostic marker in patients with ESCC.
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1 

Kamangar F, Dores GM and Anderson WF: Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol. 24:2137–2150. 2006. View Article : Google Scholar : PubMed/NCBI

2 

Song Y, Li L, Ou Y, Gao Z, Li E, Li X, Zhang W, Wang J, Xu L, Zhou Y, et al: Identification of genomic alterations in oesophageal squamous cell cancer. Nature. 509:91–95. 2014. View Article : Google Scholar : PubMed/NCBI

3 

Visvader JE and Lindeman GJ: Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions. Nat Rev Cancer. 8:755–768. 2008. View Article : Google Scholar : PubMed/NCBI

4 

Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J and Dirks PB: Identification of a cancer stem cell in human brain tumors. Cancer Res. 63:5821–5828. 2003.PubMed/NCBI

5 

Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, Coradini D, Pilotti S, Pierotti MA and Daidone MG: Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res. 65:5506–5511. 2005. View Article : Google Scholar : PubMed/NCBI

6 

Patrawala L, Calhoun T, Schneider-Broussard R, Li H, Bhatia B, Tang S, Reilly JG, Chandra D, Zhou J, Claypool K, et al: Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene. 25:1696–1708. 2006. View Article : Google Scholar : PubMed/NCBI

7 

Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C and De Maria R: Identification and expansion of human colon-cancer-initiating cells. Nature. 445:111–115. 2007. View Article : Google Scholar : PubMed/NCBI

8 

Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF and Simeone DM: Identification of pancreatic cancer stem cells. Cancer Res. 67:1030–1037. 2007. View Article : Google Scholar : PubMed/NCBI

9 

Eramo A, Lotti F, Sette G, Pilozzi E, Biffoni M, Di Virgilio A, Conticello C, Ruco L, Peschle C and De Maria R: Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ. 15:504–514. 2008. View Article : Google Scholar : PubMed/NCBI

10 

Tang KH, Dai YD, Tong M, Chan YP, Kwan PS, Fu L, Qin YR, Tsao SW, Lung HL, Lung ML, et al: A CD90+ tumor-initiating cell population with an aggressive signature and metastatic capacity in esophageal cancer. Cancer Res. 73:2322–2332. 2013. View Article : Google Scholar : PubMed/NCBI

11 

Li S, Yue D, Chen X, Wang L, Li J, Ping Y, Gao Q, Wang D, Zhang T, Li F, et al: Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity. Oncol Rep. 33:425–432. 2015.PubMed/NCBI

12 

Huang SD, Yuan Y, Liu XH, Gong DJ, Bai CG, Wang F, Luo JH and Xu ZY: Self-renewal and chemotherapy resistance of p75NTR positive cells in esophageal squamous cell carcinomas. BMC Cancer. 9:92009. View Article : Google Scholar : PubMed/NCBI

13 

Okano H, Kawahara H, Toriya M, Nakao K, Shibata S and Imai T: Function of RNA-binding protein Musashi-1 in stem cells. Exp Cell Res. 306:349–356. 2005. View Article : Google Scholar : PubMed/NCBI

14 

Hadziselimovic N, Vukojevic V, Peter F, Milnik A, Fastenrath M, Fenyves BG, Hieber P, Demougin P, Vogler C, de Quervain DJ, et al: Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex. Cell. 156:1153–1166. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Wang XY, Yu H, Linnoila RI, Li L, Li D, Mo B, Okano H, Penalva LO and Glazer RI: Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer. Oncotarget. 4:739–750. 2013. View Article : Google Scholar : PubMed/NCBI

16 

Simon E, Petke D, Böger C, Behrens HM, Warneke V, Ebert M and Röcken C: The spatial distribution of LGR5+ cells correlates with gastric cancer progression. PLoS One. 7:e354862012. View Article : Google Scholar : PubMed/NCBI

17 

Rezza A, Skah S, Roche C, Nadjar J, Samarut J and Plateroti M: The overexpression of the putative gut stem cell marker Musashi-1 induces tumorigenesis through Wnt and Notch activation. J Cell Sci. 123:3256–3265. 2010. View Article : Google Scholar : PubMed/NCBI

18 

Li N, Yousefi M, Nakauka-Ddamba A, Li F, Vandivier L, Parada K, Woo DH, Wang S, Naqvi AS, Rao S, et al: The Msi family of RNA-binding proteins function redundantly as intestinal oncoproteins. Cell Reports. 13:2440–2455. 2015. View Article : Google Scholar : PubMed/NCBI

19 

Götte M, Greve B, Kelsch R, Müller-Uthoff H, Weiss K, Masouleh B Kharabi, Sibrowski W, Kiesel L and Buchweitz O: The adult stem cell marker Musashi-1 modulates endometrial carcinoma cell cycle progression and apoptosis via Notch-1 and p21WAF1/CIP1. Int J Cancer. 129:2042–2049. 2011. View Article : Google Scholar : PubMed/NCBI

20 

Wang XY, Penalva LO, Yuan H, Linnoila RI, Lu J, Okano H and Glazer RI: Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival. Mol Cancer. 9:2212010. View Article : Google Scholar : PubMed/NCBI

21 

Liu DC, Yang ZL and Jiang S: Identification of musashi-1 and ALDH1 as carcinogenesis, progression, and poor-prognosis related biomarkers for gallbladder adenocarcinoma. Cancer Biomark. 8:113–121. 2010.2011. View Article : Google Scholar

22 

Hou T, Zhang W, Tong C, Kazobinka G, Huang X, Huang Y and Zhang Y: Putative stem cell markers in cervical squamous cell carcinoma are correlated with poor clinical outcome. BMC Cancer. 15:7852015. View Article : Google Scholar : PubMed/NCBI

23 

Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp JL, et al: Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. 534:407–411. 2016. View Article : Google Scholar : PubMed/NCBI

24 

Chen HY, Lin LT, Wang ML, Lee SH, Tsai ML, Tsai CC, Liu WH, Chen TC, Yang YP, Lee YY, et al: Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastoma. Oncotarget. 7:42485–42501. 2016. View Article : Google Scholar : PubMed/NCBI

25 

Moghbeli M, Rad A, Farshchian M, Taghehchian N, Gholamin M and Abbaszadegan MR: Correlation between Meis1 and Msi1 in esophageal squamous cell carcinoma. J Gastrointest Cancer. 47:273–277. 2016. View Article : Google Scholar : PubMed/NCBI

26 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

27 

McDonald JW and Pilgram TK: Nuclear expression of p53, p21 and cyclin D1 is increased in bronchioloalveolar carcinoma. Histopathology. 34:439–446. 1999. View Article : Google Scholar : PubMed/NCBI

28 

Xue LY, Hu N, Song YM, Zou SM, Shou JZ, Qian LX, Ren LQ, Lin DM, Tong T, He ZG, et al: Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma. BMC Cancer. 6:2962006. View Article : Google Scholar : PubMed/NCBI

29 

Langan RC, Mullinax JE, Ray S, Raiji MT, Schaub N, Xin HW, Koizumi T, Steinberg SM, Anderson A, Wiegand G, et al: A pilot study assessing the potential role of non-CD133 colorectal cancer stem cells as biomarkers. J Cancer. 3:231–240. 2012. View Article : Google Scholar : PubMed/NCBI

30 

Pastò A, Serafin V, Pilotto G, Lago C, Bellio C, Trusolino L, Bertotti A, Hoey T, Plateroti M, Esposito G, et al: NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cells. Cancer Res. 74:2106–2118. 2014. View Article : Google Scholar : PubMed/NCBI

31 

Liu X, Yang WT and Zheng PS: Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21, p27 and p53 in cervical carcinomas. Oncotarget. 5:10870–10885. 2014. View Article : Google Scholar : PubMed/NCBI

32 

Moghbeli M, Forghanifard MM, Sadrizadeh A, Mozaffari HM, Golmakani E and Abbaszadegan MR: Role of Msi1 and MAML1 in regulation of Notch signaling pathway in patients with esophageal squamous cell carcinoma. J Gastrointest Cancer. 46:365–369. 2015. View Article : Google Scholar : PubMed/NCBI

33 

Moghbeli M, Sadrizadeh A, Forghanifard MM, Mozaffari HM, Golmakani E and Abbaszadegan MR: Role of Msi1 and PYGO2 in esophageal squamous cell carcinoma depth of invasion. J Cell Commun Signal. 10:49–53. 2016. View Article : Google Scholar : PubMed/NCBI

34 

Kuang RG, Kuang Y, Luo QF, Zhou CJ, Ji R and Wang JW: Expression and significance of Musashi-1 in gastric cancer and precancerous lesions. World J Gastroenterol. 19:6637–6644. 2013. View Article : Google Scholar : PubMed/NCBI

35 

Ying M, Wang S, Sang Y, Sun P, Lal B, Goodwin CR, Guerrero-Cazares H, Quinones-Hinojosa A, Laterra J and Xia S: Regulation of glioblastoma stem cells by retinoic acid: Role for Notch pathway inhibition. Oncogene. 30:3454–3467. 2011. View Article : Google Scholar : PubMed/NCBI

36 

Yu F, Shi Y, Wang J, Li J, Fan D and Ai W: Deficiency of Kruppel-like factor KLF4 in mammary tumor cells inhibits tumor growth and pulmonary metastasis and is accompanied by compromised recruitment of myeloid-derived suppressor cells. Int J Cancer. 133:2872–2883. 2013.PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Qin G, Lian J, Yue D, Chen X, Nan S, Qi Y, Li B, Cui G, Li X, Zhao S, Zhao S, et al: Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma. Oncol Rep 38: 1724-1732, 2017.
APA
Qin, G., Lian, J., Yue, D., Chen, X., Nan, S., Qi, Y. ... Zhang, Y. (2017). Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma. Oncology Reports, 38, 1724-1732. https://doi.org/10.3892/or.2017.5809
MLA
Qin, G., Lian, J., Yue, D., Chen, X., Nan, S., Qi, Y., Li, B., Cui, G., Li, X., Zhao, S., Zhang, Y."Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma". Oncology Reports 38.3 (2017): 1724-1732.
Chicago
Qin, G., Lian, J., Yue, D., Chen, X., Nan, S., Qi, Y., Li, B., Cui, G., Li, X., Zhao, S., Zhang, Y."Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma". Oncology Reports 38, no. 3 (2017): 1724-1732. https://doi.org/10.3892/or.2017.5809
Copy and paste a formatted citation
x
Spandidos Publications style
Qin G, Lian J, Yue D, Chen X, Nan S, Qi Y, Li B, Cui G, Li X, Zhao S, Zhao S, et al: Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma. Oncol Rep 38: 1724-1732, 2017.
APA
Qin, G., Lian, J., Yue, D., Chen, X., Nan, S., Qi, Y. ... Zhang, Y. (2017). Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma. Oncology Reports, 38, 1724-1732. https://doi.org/10.3892/or.2017.5809
MLA
Qin, G., Lian, J., Yue, D., Chen, X., Nan, S., Qi, Y., Li, B., Cui, G., Li, X., Zhao, S., Zhang, Y."Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma". Oncology Reports 38.3 (2017): 1724-1732.
Chicago
Qin, G., Lian, J., Yue, D., Chen, X., Nan, S., Qi, Y., Li, B., Cui, G., Li, X., Zhao, S., Zhang, Y."Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma". Oncology Reports 38, no. 3 (2017): 1724-1732. https://doi.org/10.3892/or.2017.5809
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