Long non-coding RNAs on the stage of cervical cancer (Review)

  • Authors:
    • Junxue Dong
    • Manman Su
    • Weiqin Chang
    • Kun Zhang
    • Shuying Wu
    • Tianmin Xu
  • View Affiliations

  • Published online on: August 14, 2017     https://doi.org/10.3892/or.2017.5905
  • Pages: 1923-1931
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Abstract

Cervical cancer is one of most malignant gynecological tumors. However, effective means for diagnosing and treating cervical cancer have yet to be identified. A few decades ago, long non-coding RNAs (lncRNAs) were regarded as useless parts of the genome, however, increasing data have demonstrated the importance of lncRNAs in the diagnosis and treatment of cervical cancers. The aim of the present study is to summarize the role(s) of HOTAIR, MALAT1, CCAT2, SPRY4-IT1, RSU1P2, CCHE1, lncRNA-EBIC and PVT1. Approximately 14 lncRNAs are involved in cervical cancer and several important proteins, miRNAs and other molecules and play crucial roles in a few traditional signaling pathways that have been proven to be related to those lncRNAs. In conclusion, lncRNAs may be useful as exact treatment targets and diagnostic biomarkers for improving therapies in cervical cancer patients and lncRNAs may contribute to effective diagnosis and treatment methods for cervical cancer.
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October-2017
Volume 38 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Dong J, Su M, Chang W, Zhang K, Wu S and Xu T: Long non-coding RNAs on the stage of cervical cancer (Review). Oncol Rep 38: 1923-1931, 2017
APA
Dong, J., Su, M., Chang, W., Zhang, K., Wu, S., & Xu, T. (2017). Long non-coding RNAs on the stage of cervical cancer (Review). Oncology Reports, 38, 1923-1931. https://doi.org/10.3892/or.2017.5905
MLA
Dong, J., Su, M., Chang, W., Zhang, K., Wu, S., Xu, T."Long non-coding RNAs on the stage of cervical cancer (Review)". Oncology Reports 38.4 (2017): 1923-1931.
Chicago
Dong, J., Su, M., Chang, W., Zhang, K., Wu, S., Xu, T."Long non-coding RNAs on the stage of cervical cancer (Review)". Oncology Reports 38, no. 4 (2017): 1923-1931. https://doi.org/10.3892/or.2017.5905