|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2016. CA Cancer J Clin. 66:7–30. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lucas JM, Heinlein C, Kim T, Hernandez SA,
Malik MS, True LD, Morrissey C, Corey E, Montgomery B, Mostaghel E,
et al: The androgen-regulated protease TMPRSS2 activates a
proteolytic cascade involving components of the tumor
microenvironment and promotes prostate cancer metastasis. Cancer
Discov. 4:1310–1325. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Shah ET, Upadhyaya A, Philp LK, Tang T,
Skalamera D, Gunter J, Nelson CC, Williams ED and Hollier BG:
Repositioning ‘old’ drugs for new causes: Identifying new
inhibitors of prostate cancer cell migration and invasion. Clin Exp
Metastasis. 33:385–399. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Abdullaev IF, Bisaillon JM, Potier M,
Gonzalez JC, Motiani RK and Trebak M: Stim1 and Orai1 mediate CRAC
currents and store-operated calcium entry important for endothelial
cell proliferation. Circ Res. 103:1289–1299. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Berridge MJ, Lipp P and Bootman MD: The
versatility and universality of calcium signalling. Nat Rev Mol
Cell Biol. 1:11–21. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
6
|
Hu J, Qin K, Zhang Y, Gong J, Li N, Lv D,
Xiang R and Tan X: Downregulation of transcription factor Oct4
induces an epithelial-to-mesenchymal transition via enhancement of
Ca2+ influx in breast cancer cells. Biochem Biophys Res
Commun. 411:786–791. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Lee KP, Yuan JP, Hong JH, So I, Worley PF
and Muallem S: An endoplasmic reticulum/plasma membrane junction:
STIM1/Orai1/TRPCs. FEBS Lett. 584:2022–2027. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Yang S, Zhang JJ and Huang XY: Orai1 and
STIM1 are critical for breast tumor cell migration and metastasis.
Cancer Cell. 15:124–134. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen YF, Chiu WT, Chen YT, Lin PY, Huang
HJ, Chou CY, Chang HC, Tang MJ and Shen MR: Calcium store sensor
stromal-interaction molecule 1-dependent signaling plays an
important role in cervical cancer growth, migration, and
angiogenesis. Proc Natl Acad Sci USA. 108:pp. 15225–15230. 2011;
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Yang N, Tang Y, Wang F, Zhang H, Xu D,
Shen Y, Sun S and Yang G: Blockade of store-operated
Ca2+ entry inhibits hepatocarcinoma cell migration and
invasion by regulating focal adhesion turnover. Cancer Lett.
330:163–169. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li G, Zhang Z, Wang R, Ma W, Yang Y, Wei J
and Wei Y: Suppression of STIM1 inhibits human glioblastoma cell
proliferation and induces G0/G1 phase arrest. J Exp Clin Cancer
Res. 32:202013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
King D, Yeomanson D and Bryant HE: PI3King
the lock: Targeting the PI3K/Akt/mTOR pathway as a novel
therapeutic strategy in neuroblastoma. J Pediatr Hematol Oncol.
37:245–251. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Chen X, Wang YW, Xing AY, Xiang S, Shi DB,
Liu L, Li YX and Gao P: Suppression of SPIN1-mediated PI3K-Akt
pathway by miR-489 increases chemosensitivity in breast cancer. J
Pathol. 239:459–472. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Broek R Vander, Mohan S, Eytan DF, Chen Z
and Van Waes C: The PI3K/Akt/mTOR axis in head and neck cancer:
Functions, aberrations, cross-talk, and therapies. Oral Dis.
21:815–825. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Kim D, Kim S, Koh H, Yoon SO, Chung AS,
Cho KS and Chung J: Akt/PKB promotes cancer cell invasion via
increased motility and metalloproteinase production. FASEB J.
15:1953–1962. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yoeli-Lerner M, Yiu GK, Rabinovitz I,
Erhardt P, Jauliac S and Toker A: Akt blocks breast cancer cell
motility and invasion through the transcription factor NFAT. Mol
Cell. 20:539–550. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Tanno S, Tanno S, Mitsuuchi Y, Altomare
DA, Xiao GH and Testa JR: AKT activation up-regulates insulin-like
growth factor I receptor expression and promotes invasiveness of
human pancreatic cancer cells. Cancer Res. 61:589–593.
2001.PubMed/NCBI
|
|
18
|
Mundi PS, Sachdev J, McCourt C and
Kalinsky K: AKT in cancer: New molecular insights and advances in
drug development. Br J Clin Pharmacol. 82:943–956. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Yang SX, Polley E and Lipkowitz S: New
insights on PI3K/AKT pathway alterations and clinical outcomes in
breast cancer. Cancer Treat Rev. 45:87–96. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chen H, Zhou L, Wu X, Li R, Wen J, Sha J
and Wen X: The PI3K/AKT pathway in the pathogenesis of prostate
cancer. Front Biosci. 21:1084–1091. 2016. View Article : Google Scholar
|
|
21
|
Foster K, Wang Y, Zhou D and Wright C:
Dependence on PI3K/Akt signaling for malignant rhabdoid tumor cell
survival. Cancer Chemother Pharmacol. 63:783–791. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Magee JA, Araki T, Patil S, Ehrig T, True
L, Humphrey PA, Catalona WJ, Watson MA and Milbrandt J: Expression
profiling reveals hepsin overexpression in prostate cancer. Cancer
Res. 61:5692–5696. 2001.PubMed/NCBI
|
|
23
|
Tomlins SA, Mehra R, Rhodes DR, Cao X,
Wang L, Dhanasekaran SM, Kalyana-Sundaram S, Wei JT, Rubin MA,
Pienta KJ, et al: Integrative molecular concept modeling of
prostate cancer progression. Nat Genet. 39:41–51. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wiegert JS and Bading H:
Activity-dependent calcium signaling and ERK-MAP kinases in
neurons: A link to structural plasticity of the nucleus and gene
transcription regulation. Cell Calcium. 49:296–305. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Müller I, Lipp P and Thiel G:
Ca2+ signaling and gene transcription in
glucose-stimulated insulinoma cells. Cell Calcium. 52:137–151.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Monteith GR, McAndrew D, Faddy HM and
Roberts-Thomson SJ: Calcium and cancer: Targeting Ca2+
transport. Nat Rev Cancer. 7:519–530. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zhu M, Chen L, Zhao P, Zhou H, Zhang C, Yu
S, Lin Y and Yang X: Store-operated Ca2+ entry regulates
glioma cell migration and invasion via modulation of Pyk2
phosphorylation. J Exp Clin Cancer Res. 33:982014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Umemura M, Baljinnyam E, Feske S, De
Lorenzo MS, Xie LH, Feng X, Oda K, Makino A, Fujita T, Yokoyama U,
et al: Store-operated Ca2+ entry (SOCE) regulates
melanoma proliferation and cell migration. PLoS One. 9:e892922014.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Wu Z, Qing J, Xia Y, Wang K and Zhang F:
Suppression of stromal interaction molecule 1 inhibits SMMC7721
hepatocellular carcinoma cell proliferation by inducing cell cycle
arrest. Biotechnol Appl Biochem. 62:107–111. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Xia J, Wang H, Huang H, Sun L, Dong S,
Huang N, Shi M, Bin J, Liao Y and Liao W: Elevated Orai1 and STIM1
expressions upregulate MACC1 expression to promote tumor cell
proliferation, metabolism, migration, and invasion in human gastric
cancer. Cancer Lett. 381:31–40. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Xu Y, Zhang S, Niu H, Ye Y, Hu F, Chen S,
Li X, Luo X, Jiang S, Liu Y, et al: STIM1 accelerates cell
senescence in a remodeled microenvironment but enhances the
epithelial-to-mesenchymal transition in prostate cancer. Sci Rep.
5:117542015. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhang Y, Zhang T, Wu C, Xia Q and Xu D:
ASIC1a mediates the drug resistance of human hepatocellular
carcinoma via the Ca2+/PI3-kinase/AKT signaling pathway.
Lab Invest. 97:53–69. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Li GW, Xing WJ, Bai SZ, Hao JH, Guo J, Li
HZ, Li HX, Zhang WH, Yang BF, Wu LY, et al: The calcium-sensing
receptor mediates hypoxia-induced proliferation of rat pulmonary
artery smooth muscle cells through MEK1/ERK1,2 and PI3K pathways.
Basic Clin Pharmacol Toxicol. 108:185–193. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Divolis G, Mavroeidi P, Mavrofrydi O and
Papazafiri P: Differential effects of calcium on PI3K-Akt and
HIF-1α survival pathways. Cell Biol Toxicol. 32:437–449. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Liu ZM, Chen GG, Vlantis AC, Tse GM, Shum
CK and van Hasselt CA: Calcium-mediated activation of PI3K and p53
leads to apoptosis in thyroid carcinoma cells. Cell Mol Life Sci.
64:1428–1436. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wang C, Chi Y, Li J, Miao Y, Li S, Su W,
Jia S, Chen Z, Du S, Zhang X, et al: FAM3A activates PI3K p110α/Akt
signaling to ameliorate hepatic gluconeogenesis and lipogenesis.
Hepatology. 59:1779–1790. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Danciu TE, Adam RM, Naruse K, Freeman MR
and Hauschka PV: Calcium regulates the PI3K-Akt pathway in
stretched osteoblasts. FEBS Lett. 536:193–197. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Ke L, Xiang Y, Guo X, Lu J, Xia W, Yu Y,
Peng Y, Wang L, Wang G, Ye Y, et al: c-Src activation promotes
nasopharyngeal carcinoma metastasis by inducing the
epithelial-mesenchymal transition via PI3K/Akt signaling pathway: A
new and promising target for NPC. Oncotarget. 7:28340–28355. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Niessner H, Schmitz J, Tabatabai G, Schmid
AM, Calaminus C, Sinnberg T, Weide B, Eigentler TK, Garbe C,
Schittek B, et al: PI3K pathway inhibition achieves potent
antitumor activity in melanoma brain metastases in vitro and in
vivo. Clin Cancer Res. 22:5818–5828. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kim MS, Lee WS, Jeong J, Kim SJ and Jin W:
Induction of metastatic potential by TrkB via activation of
IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer. Oncotarget.
6:40158–40171. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Mungai PT, Waypa GB, Jairaman A, Prakriya
M, Dokic D, Ball MK and Schumacker PT: Hypoxia triggers AMPK
activation through reactive oxygen species-mediated activation of
calcium release-activated calcium channels. Mol Cell Biol.
31:3531–3545. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Sundivakkam PC, Natarajan V, Malik AB and
Tiruppathi C: Store-operated Ca2+ entry (SOCE) induced
by protease-activated receptor-1 mediates STIM1 protein
phosphorylation to inhibit SOCE in endothelial cells through
AMP-activated protein kinase and p38β mitogen-activated protein
kinase. J Biol Chem. 288:17030–17041. 2013. View Article : Google Scholar : PubMed/NCBI
|
