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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2017 Volume 38 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

DNA methylation and histone modifications as epigenetic regulation in prostate cancer (Review)

Maria Nowacka-Zawisza, Ewelina Wiśnik
Pages: 2587-2596
Published online on: 20 September 2017

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Article Open Access

Inhibitor of β-catenin and TCF (ICAT) promotes cervical cancer growth and metastasis by disrupting E-cadherin/β-catenin complex

Yayun Jiang, Wei Ren, Weijia Wang, Jing Xia, Liyao Gou, Mengyao Liu, Qun Wan, Lan Zhou, Yaguang Weng, Tongchuan He, Yan Zhang
Pages: 2597-2606
Published online on: 18 September 2017

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Article Open Access

Screening and identification of key biomarkers in hepatocellular carcinoma: Evidence from bioinformatic analysis

Lin Li, Qingsong Lei, Shujun Zhang, Lingna Kong, Bo Qin
Pages: 2607-2618
Published online on: 07 September 2017

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Article Open Access

α7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the JAK2/STAT3 signaling pathway

Rushan Fei, Yuanwei Zhang, Saisai Wang, Tao Xiang, Wenbin Chen
Pages: 2619-2628
Published online on: 04 September 2017

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Article Open Access

Suppression of STIM1 inhibits the migration and invasion of human prostate cancer cells and is associated with PI3K/Akt signaling inactivation

Yibin Zhou, Peng Gu, Jian Li, Feng Li, Jin Zhu, Peng Gao, Yachen Zang, Yongchang Wang, Yuxi Shan, Dongrong Yang
Pages: 2629-2636
Published online on: 18 September 2017

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Article Open Access

Upregulation of MUC1 by its novel activator 14-3-3ζ promotes tumor invasion and indicates poor prognosis in lung adenocarcinoma

Min Xue, Weimin Tao
Pages: 2637-2646
Published online on: 07 September 2017

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Article Open Access

Irisin reverses the IL-6 induced epithelial-mesenchymal transition in osteosarcoma cell migration and invasion through the STAT3/Snail signaling pathway

Gang Kong, Yunpeng Jiang, Xiujiang Sun, Zhilin Cao, Guodong Zhang, Zhongyuan Zhao, Yong Zhao, Qian Yu, Gong Cheng
Pages: 2647-2656
Published online on: 20 September 2017

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Article Open Access

Synergistic antitumor effects of the combined treatment with an HDAC6 inhibitor and a COX-2 inhibitor through activation of PTEN

Guanhua Zhang, Ye-Hua Gan
Pages: 2657-2666
Published online on: 21 September 2017

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Article Open Access

SSRP1 silencing inhibits the proliferation and malignancy of human glioma cells via the MAPK signaling pathway

Jianming Liao, Xiang Tao, Qianshan Ding, Junhui Liu, Xue Yang, Fan-En Yuan, Ji-An Yang, Baohui Liu, Guo-An Xiang, Qianxue Chen
Pages: 2667-2676
Published online on: 21 September 2017

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Article Open Access

SP1 promotes tumor angiogenesis and invasion by activating VEGF expression in an acquired trastuzumab‑resistant ovarian cancer model

Feng Su, Jing Geng, Xinying Li, Chuan Qiao, Longlong Luo, Jiannan Feng, Xinjun Dong, Ming Lv
Pages: 2677-2684
Published online on: 25 September 2017

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Article Open Access

Capsaicin inhibits proliferation and induces apoptosis in osteosarcoma cell lines via the mitogen‑activated protein kinase pathway

Yuan Zhang, Xu Deng, Tao Lei, Chang Yu, Yang Wang, Guosheng Zhao, Xiaoji Luo, Ke Tang, Zhengxue Quan, Dianming Jiang
Pages: 2685-2696
Published online on: 18 September 2017

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Article Open Access

De novo synthesis of C4.4A in hepatocellular carcinoma promotes migration and invasion of tumor cells

Magdalena Görtz, Uwe Galli, Thomas Longerich, Margot Zöller, Ulrike Erb, Peter Schemmer
Pages: 2697-2704
Published online on: 20 September 2017

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Article Open Access

Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4

Zhiheng Li, Xiaolu Li, Lixiao Xu, Yanfang Tao, Chun Yang, Xiaolan Chen, Fang Fang, Yi Wu, Xin Ding, He Zhao, Mei Li, Guanghui Qian, Yunyun Xu, Junli Ren, Weiwei Du, Jian Wang, Jun Lu, Shaoyan Hu, Jian Pan
Pages: 2705-2716
Published online on: 22 September 2017

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Article Open Access

miR-1908 as a novel prognosis marker of glioma via promoting malignant phenotype and modulating SPRY4/RAF1 axis

Zhi Chai, Huijie Fan, Yanyan Li, Lijuan Song, Xiaoming Jin, Jiezhong Yu, Yanhua Li, Cungen Ma, Ran Zhou
Pages: 2717-2726
Published online on: 26 September 2017

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Article Open Access

MicroRNA-154 as a prognostic factor in bladder cancer inhibits cellular malignancy by targeting RSF1 and RUNX2

Xin Zhao, Zhigang Ji, Yi Xie, Guanghua Liu, Hanzhong Li
Pages: 2727-2734
Published online on: 25 September 2017

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Article Open Access

miR-146a and miR-146b in the diagnosis and prognosis of papillary thyroid carcinoma

Zhenwei Qiu, Hai Li, Jianwei Wang, Chongbing Sun
Pages: 2735-2740
Published online on: 25 September 2017

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Article Open Access

Phenotype characterization of human melanoma cells resistant to dabrafenib

Fabiola Gilda Cordaro, Anna Lisa De Presbiteris, Rosa Camerlingo, Nicola Mozzillo, Giuseppe Pirozzi, Ernesta Cavalcanti, Antonella Manca, Giuseppe Palmieri, Antonio Cossu, Gennaro Ciliberto, Paolo A. Ascierto, Salvatore Travali, Eduardo J. Patriarca, Emilia Caputo
Pages: 2741-2751
Published online on: 18 September 2017

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Article Open Access

MicroRNA-345 inhibits metastasis and epithelial-mesenchymal transition of gastric cancer by targeting FOXQ1

Aiwen Feng, Xiaoming Yuan, Xiangwei Li
Pages: 2752-2760
Published online on: 26 September 2017

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Article Open Access

VEGFR3 inhibition chemosensitizes lung adenocarcinoma A549 cells in the tumor-associated macrophage microenvironment through upregulation of p53 and PTEN

Ya Li, Yaguang Weng, Liang Zhong, Huimin Chong, Sicheng Chen, Yanting Sun, Wang Li, Qiong Shi
Pages: 2761-2773
Published online on: 19 September 2017

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Article Open Access

Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer

Namrata Khurana, Hogyoung Kim, Partha K. Chandra, Sudha Talwar, Pankaj Sharma, Asim B. Abdel-Mageed, Suresh C. Sikka, Debasis Mondal
Pages: 2774-2786
Published online on: 30 August 2017

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Article Open Access

High pemetrexed sensitivity of docetaxel-resistant A549 cells is mediated by TP53 status and downregulated thymidylate synthase

Wei-Ting Kuo, Dom-Gene Tu, Ling-Yen Chiu, Gwo-Tarng Sheu, Ming-Fang Wu
Pages: 2787-2795
Published online on: 07 September 2017

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Article Open Access

Silencing of histone methyltransferase NSD3 reduces cell viability in osteosarcoma with induction of apoptosis

Zhiwei Liu, Lianhua Piao, Ming Zhuang, Xubin Qiu, Xiaoshuang Xu, Dawei Zhang, Mengmeng Liu, Ding Ren
Pages: 2796-2802
Published online on: 04 September 2017

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Article Open Access

The ethanol extracts of sporoderm-broken spores of Ganoderma lucidum inhibit colorectal cancer in vitro and in vivo

Kang Li, Kun Na, Tingting Sang, Kaikai Wu, Ying Wang, Xingya Wang
Pages: 2803-2813
Published online on: 27 September 2017

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Article Open Access

Predicting radiotherapy response for patients with soft tissue sarcoma by developing a molecular signature

Zaixiang Tang, Qinghua Zeng, Yan Li, Xinyan Zhang, Mark J. Suto, Bo Xu, Nengjun Yi
Pages: 2814-2824
Published online on: 25 September 2017

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Article Open Access

Telmisartan inhibits hepatocellular carcinoma cell proliferation in vitro by inducing cell cycle arrest

Kyoko Oura, Tomoko Tadokoro, Shintaro Fujihara, Asahiro Morishita, Taiga Chiyo, Eri Samukawa, Yoshimi Yamana, Koji Fujita, Teppei Sakamoto, Takako Nomura, Hirohito Yoneyama, Hideki Kobara, Hirohito Mori, Hisakazu Iwama, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 2825-2835
Published online on: 20 September 2017

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Article Open Access

TGX-221 inhibits proliferation and induces apoptosis in human glioblastoma cells

Xue Yang, Ji-An Yang, Bao-Hui Liu, Jian-Ming Liao, Fan‑En Yuan, Yin-Qiu Tan, Qian-Xue Chen
Pages: 2836-2842
Published online on: 22 September 2017

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Article Open Access

Reversal effect of adenovirus-mediated human interleukin 24 transfection on the cisplatin resistance of A549/DDP lung cancer cells

Mingju Xu, Xioawei Tang, Jinjin Guo, Wangbang Sun, Faqing Tang
Pages: 2843-2851
Published online on: 26 September 2017

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Article

Low heme oxygenase-1 expression promotes gastric cancer cell apoptosis, inhibits proliferation and invasion, and correlates with increased overall survival in gastric cancer patients

Quan-Guang Ren, Sheng-Li Yang, Pin-Dong Li, Jin-Rong Xiong, Xiefan Fang, Jian-Li Hu, Qiu-Shuang Wang, Ren-Wang Chen, Ye-Shan Chen, Lu Wen, Miao Peng
Pages: 2852-2858
Published online on: 19 September 2017

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Article

The uptake exploration of 68Ga-labeled NGR in well-differentiated hepatocellular carcinoma xenografts: Indication for the new clinical translational of a tracer based on NGR

Yongheng Gao, Zhengjie Wang, Xiaowei Ma, Wenhui Ma, Mingxuan Zhao, Tianming Fu, Guoquan Li, Shengjun Wang, Zhe Wang, Weidong Yang, Fei Kang, Jing Wang
Pages: 2859-2866
Published online on: 31 August 2017

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Article

Molecular iodine impairs chemoresistance mechanisms, enhances doxorubicin retention and induces downregulation of the CD44+/CD24+ and E-cadherin+/vimentin+ subpopulations in MCF-7 cells resistant to low doses of doxorubicin

Alexander Bontempo, Brenda Ugalde-Villanueva, Evangelina Delgado‑González, Ángel Luis Rodríguez, Carmen Aceves
Pages: 2867-2876
Published online on: 01 September 2017

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Article

Naringenin inhibits alcoholic injury by improving lipid metabolism and reducing apoptosis in zebrafish larvae

Haiyan Lin, Zhenting Zhou, Weichao Zhong, Peng Huang, Ning Ma, Yuqing Zhang, Chuying Zhou, Yuling Lai, Shaohui Huang, Haiyan An, Xuegang Sun, Lei Gao, Zhiping Lv
Pages: 2877-2884
Published online on: 19 September 2017

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Article

Cx32 inhibits TNFα-induced extrinsic apoptosis with and without EGFR suppression

Yongchang Lai, Liang Tao, Yifan Zhao, Xiaomin Zhang, Xingjuan Sun, Qin Wang, Chengfang Xu
Pages: 2885-2892
Published online on: 07 September 2017

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Article

Hypoxia promotes migration/invasion and glycolysis in head and neck squamous cell carcinoma via an HIF-1α-MTDH loop

Gangcai Zhu, Fusen Peng, Wei Gong, Li She, Ming Wei, Haolei Tan, Changhan Chen, Diekuo Zhang, Guo Li, Donghai Huang, Xin Zhang, Yong Liu
Pages: 2893-2900
Published online on: 07 September 2017

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Article

Inositol hexaphosphate hydrolysate competitively binds to AKT to inhibit the proliferation of colon carcinoma

Chen Chen, Fuguo Yang, Cuiping Liu, Lianhua Cui, Min Fu, Yang Song
Pages: 2901-2910
Published online on: 07 September 2017

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Article

PomGnT1 enhances temozolomide resistance by activating epithelial-mesenchymal transition signaling in glioblastoma

Qi Liu, Yajun Xue, Qingshan Chen, Huairui Chen, Xiaofei Zhang, Leiping Wang, Cong Han, Shuanglin Que, Meiqing Lou, Jin Lan
Pages: 2911-2918
Published online on: 19 September 2017

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Article

Radioiodine-labeled anti-epidermal growth factor receptor binding bovine serum albumin-polycaprolactone for targeting imaging of glioblastoma

Chengxia Li, Jian Tan, Jin Chang, Wei Li, Zhongyun Liu, Ning Li, Yanhui Ji
Pages: 2919-2926
Published online on: 04 September 2017

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Article

Harmine suppresses the proliferation and migration of human ovarian cancer cells through inhibiting ERK/CREB pathway

Jun Gao, Hong Zhu, Hong Wan, Xia Zou, Xiaoxin Ma, Guolan Gao
Pages: 2927-2934
Published online on: 13 September 2017

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Article

Suppression of LETM1 by siRNA inhibits cell proliferation and invasion of bladder cancer cells

Bisheng Huang, Jingwei Zhang, Xiaolu Zhang, Chi Huang, Guanghui Hu, Saiyang Li, Tiancheng Xie, Mengnan Liu, Yunfei Xu
Pages: 2935-2940
Published online on: 18 September 2017

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Article

miR‑146b‑5p suppresses glioblastoma cell resistance to temozolomide through targeting TRAF6

Zhongrun Qian, Sunhai Zhou, Zhiyi Zhou, Xi Yang, Shuanlin Que, Jin Lan, Yongming Qiu, Yingying Lin
Pages: 2941-2950
Published online on: 19 September 2017

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Article

Celastrol downregulates E2F1 to induce growth inhibitory effects in hepatocellular carcinoma HepG2 cells

Liang Ma, Lei Peng, Sheng Fang, Bangguo He, Zi Liu
Pages: 2951-2958
Published online on: 19 September 2017

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Article

Interaction with neutrophils promotes gastric cancer cell migration and invasion by inducing epithelial-mesenchymal transition

Wen Zhang, Jianmei Gu, Jingyan Chen, Peng Zhang, Runbi Ji, Hui Qian, Wenrong Xu, Xu Zhang
Pages: 2959-2966
Published online on: 06 September 2017

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Article

Overexpression of RAB34 correlates with poor prognosis and tumor progression in hepatocellular carcinoma

Jianwu Wu, Yijie Lu, Ancheng Qin, Zhiming Qiao, Xinwei Jiang
Pages: 2967-2974
Published online on: 18 September 2017

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Article

Novel transduction of nutrient stress to Notch pathway by RasGRP3 promotes malignant aggressiveness in human esophageal squamous cell carcinoma

Ge Hu, Yuepeng Zhou, Yu Zhu, Ling Zhou, Rui Ling, Dan Wu, Lei Mi, Xuefeng Wang, Dongfang Dai, Chaoming Mao, Deyu Chen
Pages: 2975-2984
Published online on: 25 September 2017

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Article

Biochanin-A induces apoptosis and suppresses migration in FaDu human pharynx squamous carcinoma cells

In-A Cho, Sang-Joun You, Kyeong-Rok Kang, Su-Gwan Kim, Ji-Su Oh, Jae-Seek You, Gyeong-Je Lee, Yo-Seob Seo, Do Kyung Kim, Chun Sung Kim, Sook-Young Lee, Jae-Sung Kim
Pages: 2985-2992
Published online on: 13 September 2017

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Article

miR-504 promotes tumour growth and metastasis in human osteosarcoma by targeting TP53INP1 Corrigendum in /10.3892/or.2025.8914

Qingchun Cai, Sixiang Zeng, Xing Dai, Junlong Wu, Wei Ma
Pages: 2993-3000
Published online on: 21 September 2017

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Article

Effects of FSTL1 on cell proliferation in breast cancer cell line MDA‑MB‑231 and its brain metastatic variant MDA‑MB‑231‑BR

Jiaqiang An, Lulu Wang, Yuanli Zhao, Qiang Hao, Ying Zhang, Jingyi Zhang, Chun Yang, Li Liu, Wenjuan Wang, Dongliang Fang, Tao Lu, Yan Gao
Pages: 3001-3010
Published online on: 26 September 2017

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Article

Baicalein inhibits tumor progression by inhibiting tumor cell growth and tumor angiogenesis

Yang-Gyu Park, Jawun Choi, Hye-Kang Jung, Bumseok Kim, Chan Kim, Sang-Youel Park, Jae-Won Seol
Pages: 3011-3018
Published online on: 26 September 2017

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Article

SLC7A11, a component of cysteine/glutamate transporter, is a novel biomarker for the diagnosis and prognosis in laryngeal squamous cell carcinoma

Zhihong Ma, Hong Zhang, Meng Lian, Changli Yue, Gehong Dong, Yulan Jin, Rui Li, Hongfei Wan, Ru Wang, Ying Wang, Jie Zhai, Hongzhi Ma, Ling Feng, Jianfeng Han, Shuzhou Liu, Youxin Guo, Jianhua Li, Yu Liu, Jugao Fang, Honggang Liu
Pages: 3019-3029
Published online on: 20 September 2017

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Article

miR-25 promotes metastasis via targeting FBXW7 in esophageal squamous cell carcinoma Retraction in /10.3892/or.2023.8644

Ye Hua, Kai Zhao, Gang Tao, Chunhua Dai, Yuting Su
Pages: 3030-3038
Published online on: 25 September 2017

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Article

miR106b regulates retinoblastoma Y79 cells through Runx3

Ge Yang, Yang Fu, Luxi Zhang, Xiaoyan Lu, Qiuming Li
Pages: 3039-3043
Published online on: 30 August 2017

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Article

1H-NMR-based metabolic profiling of a colorectal cancer CT-26 lung metastasis model in mice

Yan Li, Chunting Wang, Dandan Li, Pengchi Deng, Xiaoni Shao, Jing Hu, Chunqi Liu, Hui Jie, Yiyun Lin, Zhuoling Li, Xinying Qian, Huaqin Zhang, Yinglan Zhao
Pages: 3044-3054
Published online on: 13 September 2017

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Article

MEK inhibitor, PD98059, promotes breast cancer cell migration by inducing β-catenin nuclear accumulation

Ying Zhao, Chao-Chao Ge, Jun Wang, Xiao-Xiao Wu, Xiao-Min Li, Wei Li, Sha-Sha Wang, Tong Liu, Jiu-Zhou Hou, Hua Sun, Dong Fang, Song-Qiang Xie
Pages: 3055-3063
Published online on: 13 September 2017

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Article

Inhibition of miR-23a increases the sensitivity of lung cancer stem cells to erlotinib through PTEN/PI3K/Akt pathway

Zhijun Han, Xiaoyun Zhou, Shanqing Li, Yingzhi Qin, Yeye Chen, Hongsheng Liu
Pages: 3064-3070
Published online on: 04 September 2017

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Article

MicroRNA-381 serves as a prognostic factor and inhibits migration and invasion in non-small cell lung cancer by targeting LRH-1 Retraction in /10.3892/or.2023.8640

Chunyan Tian, Jun Li, Lili Ren, Ren Peng, Binbin Chen, Yumei Lin
Pages: 3071-3077
Published online on: 14 September 2017

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Article

Regulation of UHRF1 by microRNA-378 modulates medulloblastoma cell proliferation and apoptosis

Zhen-Yu Zhang, Bin Zhu, Xin-Wei Zhao, Yun-Bo Zhan, Jian-Ji Bao, Jin-Qiao Zhou, Feng-Jiang Zhang, Bin Yu, Jun Liu, Yan-Min Wang, Ya-Hui Bai, Jin Hong, Xian-Zhi Liu
Pages: 3078-3084
Published online on: 04 September 2017

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Article

miRNA‑148a inhibits cell growth of papillary thyroid cancer through STAT3 and PI3K/AKT signaling pathways

Yuan Xu, Yi-Fan Han, Shao-Jun Zhu, Jian-Da Dong, Bing Ye
Pages: 3085-3093
Published online on: 07 September 2017

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Article

Salidroside, a scavenger of ROS, enhances the radioprotective effect of Ex-RAD® via a p53-dependent apoptotic pathway

Tian Feng, Libin Wang, Nan Zhou, Chang Liu, Jiahui Cui, Rangxin Wu, Juan Jing, Shengyong Zhang, Hui Chen, Siwang Wang
Pages: 3094-3102
Published online on: 06 September 2017

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Article

DAL-1 attenuates epithelial to mesenchymal transition and metastasis by suppressing HSPA5 expression in non-small cell lung cancer

Xiaoliu Qiu, Xiaoying Guan, Wanxia Liu, Yajie Zhang
Pages: 3103-3113
Published online on: 26 September 2017

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Article

The antitumor effects of arsenic trioxide in mantle cell lymphoma via targeting Wnt/β‑catenin pathway and DNA methyltransferase-1

Xin-Yu Li, Ying Li, Lingyan Zhang, Xin Liu, Lili Feng, Xin Wang
Pages: 3114-3120
Published online on: 07 September 2017

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Article

MicroRNA-1297 inhibits metastasis and epithelial-mesenchymal transition by targeting AEG-1 in cervical cancer Retraction in /10.3892/or.2022.8372

Zengyan Wang, Shanyang He, Peng Guo, Xu Guo, Jingxuan Zheng
Pages: 3121-3129
Published online on: 20 September 2017

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Article

Decreased expression of the augmenter of liver regeneration results in growth inhibition and increased chemosensitivity of acute T lymphoblastic leukemia cells

Yan Shen, Qi Liu, Shifeng Lou, Yun Luo, Hang Sun, Hanqing Zeng, Jianchuan Deng
Pages: 3130-3136
Published online on: 21 September 2017

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Article

Autophagy induction enhances tetrandrine-induced apoptosis via the AMPK/mTOR pathway in human bladder cancer cells

Bo Kou, Wei Liu, Xu Xu, Yang Yang, Qiuyue Yi, Fengwei Guo, Jianpeng Li, Jinsong Zhou, Qingshan Kou
Pages: 3137-3143
Published online on: 21 September 2017

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Article

MicroRNA-520c-3p negatively regulates EMT by targeting IL-8 to suppress the invasion and migration of breast cancer

Cui-Ping Tang, Han-Jing Zhou, Jian Qin, Yi Luo, Tao Zhang
Pages: 3144-3152
Published online on: 19 September 2017

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Article

Transdifferentiation of human MNNG/HOS osteosarcoma cells into vascular endothelial cells in vitro and in vivo

Xinwen Wang, Weifeng Xu, Shenglin Wang, Feqiang Yu, Jinyi Feng, Xinwu Wang, Lurong Zhang, Jianhua Lin
Pages: 3153-3159
Published online on: 26 September 2017

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Article

Enhanced wild-type p53 expression by small activating RNA dsP53-285 induces cell cycle arrest and apoptosis in pheochromocytoma cell line PC12

Dengqiang Lin, Li Meng, Feifei Xu, Jianpo Lian, Yunze Xu, Xin Xie, Xiaojing Wang, Hongchao He, Chenghe Wang, Yu Zhu
Pages: 3160-3166
Published online on: 25 September 2017

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Article

TLR5/7-mediated PI3K activation triggers epithelial-mesenchymal transition of ovarian cancer cells through WAVE3-dependent mesothelin or OCT4/SOX2 expression

Ga Bin Park, Daejin Kim
Pages: 3167-3176
Published online on: 06 September 2017

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Article

Long non-coding RNA PAR5 inhibits the proliferation and progression of glioma through interaction with EZH2

Xiang-Peng Wang, Cai Shan, Xing-Li Deng, Li-Yan Li, Wei Ma
Pages: 3177-3186
Published online on: 21 September 2017

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Article

MicroRNA‑337 inhibits colorectal cancer progression by directly targeting KRAS and suppressing the AKT and ERK pathways Retraction in /10.3892/or.2022.8394

Xuerong Liu, Yan Wang, Jinglong Zhao
Pages: 3187-3196
Published online on: 25 September 2017

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Article

In vitro and in vivo anti-primary effusion lymphoma activities of fucoidan extracted from Cladosiphon okamuranus Tokida

Chie Ishikawa, Naoki Mori
Pages: 3197-3204
Published online on: 20 September 2017

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Article

Ribosomal protein S3 regulates XIAP expression independently of the NF-κB pathway in breast cancer cells

Hisako Ono, Yosuke Iizumi, Wakana Goi, Yoshihiro Sowa, Tetsuya Taguchi, Toshiyuki Sakai
Pages: 3205-3210
Published online on: 27 September 2017

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Article

Paclitaxel-mediated human aryl hydrocarbon receptor mRNA translation by an internal ribosomal entry site-dependent mechanism

Wen-Qing Gao, Jing Ma, Liu-Liu Sun, Qi Li, Rui-Yu Zhu, Jian Jin
Pages: 3211-3219
Published online on: 18 September 2017

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Article

miR-133b acts as a tumor suppressor and negatively regulates ATP citrate lyase via PPARγ in gastric cancer

Yunsheng Cheng, Benli Jia, Yong Wang, Shengyun Wan
Pages: 3220-3226
Published online on: 07 September 2017

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Article

Genome-wide study of ER-regulated lncRNAs shows AP000439.3 may function as a key regulator of cell cycle in breast cancer

Yin Zhang, Dan-Lan Wang, Hai-Yan Yan, Jian-You Liao, Jie-Hua He, Kai-Shun Hu, Wei-Xi Deng, Yan-Jie Wang, Hong-Tao Xing, H. Phillip Koeffler, Dong Yin
Pages: 3227-3237
Published online on: 20 September 2017

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Article

Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells

Daichi Kawamura, Yoshihiro Takemoto, Arata Nishimoto, Koji Ueno, Tohru Hosoyama, Bungo Shirasawa, Toshiki Tanaka, Naruji Kugimiya, Eijiro Harada, Kimikazu Hamano
Pages: 3238-3244
Published online on: 20 September 2017

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Article

Myeloid zinc finger 1 protein is a key transcription stimulating factor of PYROXD2 promoter

Huilin Liu, Xingyan Jiang, Tao Wang, Fang Yu, Xingzhi Wang, Jiaojiao Chen, Xiaoyuan Xie, Handong Fan
Pages: 3245-3253
Published online on: 22 September 2017

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Article

Leptin induces ROS via NOX5 in healthy and neoplastic mammary epithelial cells

Sinda Mahbouli, Audrey Der Vartanian, Sophie Ortega, Stéphanie Rougé, Marie-Paule Vasson, Adrien Rossary
Pages: 3254-3264
Published online on: 27 September 2017

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Article

SNHG15 affects the growth of glioma microvascular endothelial cells by negatively regulating miR-153 Corrigendum in /10.3892/or.2022.8267

Yawen Ma, Yixue Xue, Xiaobai Liu, Chengbin Qu, Heng Cai, Ping Wang, Zhiqing Li, Zhen Li, Yunhui Liu
Pages: 3265-3277
Published online on: 21 September 2017

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Article

The epigenetic effect of microRNA in BCR-ABL1‑positive microvesicles during the transformation of normal hematopoietic transplants

Na Shen, Lin Jiang, Qing Li, Jieke Cui, Shu Zhou, Fanjun Cheng, Zhaodong Zhong, Li Meng, Yong You, Xiaojian Zhu, Ping Zou
Pages: 3278-3284
Published online on: 19 September 2017

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Retraction Open Access

[Retracted] Efficacy of dual-functional liposomes containing paclitaxel for treatment of lung cancer

Rong-Hua Wang, Hong-Mei Cao, Zhi-Ju Tian, Bo Jin, Qing Wang, Hong Ma, Jing Wu
Pages: 3285-3285
Published online on: 26 September 2017

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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