|
1
|
Arseneault R, Chien A, Newington JT,
Rappon T, Harris R and Cumming RC: Attenuation of LDHA expression
in cancer cells leads to redox-dependent alterations in
cytoskeletal structure and cell migration. Cancer Lett.
338:255–266. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Huang D, Duan H, Huang H, Tong X, Han Y,
Ru G, Qu L, Shou C and Zhao Z: Cisplatin resistance in gastric
cancer cells is associated with HER2 upregulation-induced
epithelial-mesenchymal transition. Sci Rep. 6:205022016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Huang J, Xiao D, Li G, Ma J, Chen P, Yuan
W, Hou F, Ge J, Zhong M, Tang Y, et al: EphA2 promotes
epithelial-mesenchymal transition through the Wnt/β-catenin pathway
in gastric cancer cells. Oncogene. 33:2737–2747. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Dravis C, Spike BT, Harrell JC, Johns C,
Trejo CL, Southard-Smith EM, Perou CM and Wahl GM: Sox10 regulates
stem/progenitor and mesenchymal cell states in mammary epithelial
cells. Cell Reports. 12:2035–2048. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Nasmyth K: Disseminating the genome:
Joining, resolving, and separating sister chromatids during mitosis
and meiosis. Annu Rev Genet. 35:673–745. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Laird PW: The power and the promise of DNA
methylation markers. Nat Rev Cancer. 3:253–266. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Furuta J, Nobeyama Y, Umebayashi Y, Otsuka
F, Kikuchi K and Ushijima T: Silencing of Peroxiredoxin 2 and
aberrant methylation of 33 CpG islands in putative promoter regions
in human malignant melanomas. Cancer Res. 66:6080–6086. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Okamoto Y, Sawaki A, Ito S, Nishida T,
Takahashi T, Toyota M, Suzuki H, Shinomura Y, Takeuchi I, Shinjo K,
et al: Aberrant DNA methylation associated with aggressiveness of
gastrointestinal stromal tumour. Gut. 61:392–401. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Liu D, Shen X, Zhu G and Xing M: REC8 is a
novel tumor suppressor gene epigenetically robustly targeted by the
PI3K pathway in thyroid cancer. Oncotarget. 6:39211–39224. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Xu Y, Toure F, Qu W, Lin L, Song F, Shen
X, Rosario R, Garcia J, Schmidt AM and Yan SF: Advanced glycation
end product (AGE)-receptor for AGE (RAGE) signaling and
up-regulation of Egr-1 in hypoxic macrophages. J Biol Chem.
285:23233–23240. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Sun S, Ning X, Zhai Y, Du R, Lu Y, He L,
Li R, Wu W, Sun W and Wang H: Egr-1 mediates chronic
hypoxia-induced renal interstitial fibrosis via the PKC/ERK
pathway. Am J Nephrol. 39:436–448. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Zhang H, Chen X, Wang J, Guang W, Han W,
Zhang H, Tan X and Gu Y: EGR1 decreases the malignancy of human
non-small cell lung carcinoma by regulating KRT18 expression. Sci
Rep. 4:54162014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yoon SW, Lee MS, Xaver M, Zhang L, Hong
SG, Kong YJ, Cho HR, Kleckner N and Kim KP: Meiotic prophase roles
of Rec8 in crossover recombination and chromosome structure.
Nucleic Acids Res. 44:9296–9314. 2016.PubMed/NCBI
|
|
14
|
Watanabe Y and Nurse P: Cohesin Rec8 is
required for reductional chromosome segregation at meiosis. Nature.
400:461–464. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
15
|
Cohen S, Lee D, Zhai B, Gygi SP and
Goldberg AL: Trim32 reduces PI3K-Akt-FoxO signaling in muscle
atrophy by promoting plakoglobin-PI3K dissociation. J Cell Biol.
204:747–758. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Raghavan CT and Nagaraj RH: AGE-RAGE
interaction in the TGFβ2-mediated epithelial to mesenchymal
transition of human lens epithelial cells. Glycoconj J. 33:631–643.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Song JS, Kang CM, Park CK, Yoon HK, Lee
SY, Ahn JH and Moon HS: Inhibitory effect of receptor for advanced
glycation end products (RAGE) on the TGF-β-induced alveolar
epithelial to mesenchymal transition. Exp Mol Med. 43:517–524.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Li JH, Wang W, Huang XR, Oldfield M,
Schmidt AM, Cooper ME and Lan HY: Advanced glycation end products
induce tubular epithelial-myofibroblast transition through the
RAGE-ERK1/2 MAP kinase signaling pathway. Am J Pathol.
164:1389–1397. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Jemal A, Siegel R, Xu J and Ward E: Cancer
statistics, 2010. CA Cancer J Clin. 60:277–300. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Hay ED: An overview of
epithelio-mesenchymal transformation. Acta Anat (Basel). 154:8–20.
1995. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kalluri R and Weinberg RA: The basics of
epithelial-mesenchymal transition. J Clin Invest. 119:1420–1428.
2009. View
Article : Google Scholar : PubMed/NCBI
|
|
22
|
Thiery JP, Acloque H, Huang RY and Nieto
MA: Epithelial-mesenchymal transitions in development and disease.
Cell. 139:871–890. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ozen E, Gozukizil A, Erdal E, Uren A,
Bottaro DP and Atabey N: Heparin inhibits hepatocyte growth factor
induced motility and invasion of hepatocellular carcinoma cells
through early growth response protein 1. PLoS One. 7:e427172012.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhang Z, Zhang B, Li W, Fu L, Fu L, Zhu Z
and Dong JT: Epigenetic silencing of miR-203 upregulates SNAI2 and
contributes to the invasiveness of malignant breast cancer cells.
Genes cancer. 2:782–791. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ying J, Srivastava G, Hsieh WS, Gao Z,
Murray P, Liao SK, Ambinder R and Tao Q: The stress-responsive gene
GADD45G is a functional tumor suppressor, with its response to
environmental stresses frequently disrupted epigenetically in
multiple tumors. Clin Cancer Res. 11:6442–6449. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Regel I, Eichenmüller M, Joppien S, Liebl
J, Häberle B, Müller-Höcker J, Vollmar A, von Schweinitz D and
Kappler R: IGFBP3 impedes aggressive growth of pediatric liver
cancer and is epigenetically silenced in vascular invasive and
metastatic tumors. Mol Cancer. 11:92012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Pruitt SC, Bailey KJ and Freeland A:
Reduced Mcm2 expression results in severe stem/progenitor cell
deficiency and cancer. Stem Cells. 25:3121–3132. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Medina-Ramirez CM, Goswami S, Smirnova T,
Bamira D, Benson B, Ferrick N, Segall J, Pollard JW and Kitsis RN:
Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis,
and chemoresistance. Cancer Res. 71:7705–7715. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Liu JY, Qian D, He LR, Li YH, Liao YJ, Mai
SJ, Tian XP, Liu YH, Zhang JX, Kung HF, et al: PinX1 suppresses
bladder urothelial carcinoma cell proliferation via the inhibition
of telomerase activity and p16/cyclin D1 pathway. Mol Cancer.
12:1482013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kim MO, Lee YJ, Park JH, Ryu JM, Yun SP
and Han HJ: PKA and cAMP stimulate proliferation of mouse embryonic
stem cells by elevating GLUT1 expression mediated by the NF-κB and
CREB/CBP signaling pathways. Biochim Biophys Acta. 1820:1636–1646.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Kabbout M, Garcia MM, Fujimoto J, Liu DD,
Woods D, Chow CW, Mendoza G, Momin AA, James BP, Solis L, et al:
ETS2 mediated tumor suppressive function and MET oncogene
inhibition in human non-small cell lung cancer. Clin Cancer Res.
19:1–3395. 2013. View Article : Google Scholar
|
|
32
|
Du W, Jiang P, Mancuso A, Stonestrom A,
Brewer MD, Minn AJ, Mak TW, Wu M and Yang X: TAp73 enhances the
pentose phosphate pathway and supports cell proliferation. Nat Cell
Biol. 15:991–1000. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
33
|
Deep G, Jain AK, Ramteke A, Ting H,
Vijendra KC, Gangar SC, Agarwal C and Agarwal R: SNAI1 is critical
for the aggressiveness of prostate cancer cells with low
E-cadherin. Mol Cancer. 13:372014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Yu J, Liang Q, Wang J, Wang K, Gao J,
Zhang J, Zeng Y, Chiu PW, Ng EK and Sung JJ: REC8 functions as a
tumor suppressor and is epigenetically downregulated in gastric
cancer, especially in EBV-positive subtype. Oncogene. 36:182–193.
2017. View Article : Google Scholar : PubMed/NCBI
|
