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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2018 Volume 39 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Novel structural approaches concerning HPV proteins: Insight into targeted therapies for cervical cancer (Review)

Kalliopi I. Pappa, Georgia Kontostathi, Vasiliki Lygirou, Jerome Zoidakis, Nicholas P. Anagnou
Pages: 1547-1554
Published online on: 09 February 2018

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Article

Prognostic impact of sarcopenia and its correlation with circulating miR-21 in colorectal cancer patients

Yoshinaga Okugawa, Li Yao, Yuji Toiyama, Akira Yamamoto, Tsunehiko Shigemori, Chengzeng Yin, Yusuke Omura, Shozo Ide, Takahito Kitajima, Tadanobu Shimura, Hiroyuki Fujikawa, Hiromi Yasuda, Junichiro Hiro, Shigeyuki Yoshiyama, Minako Kobayashi, Koji Tanaka, Yasuhiro Inoue, Toshimitsu Araki, Chikao Miki, Masato Kusunoki
Pages: 1555-1564
Published online on: 14 February 2018

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Article

Knockdown of end-binding protein 1 induces apoptosis in radioresistant A549 lung cancer cells via p38 kinase-dependent COX-2 upregulation

Jeong-Hwa Baek, Ji-Hye Yim, Jie-Young Song, Hong-Duck Um, Jong Kuk Park, In-Chul Park, Jae-Sung Kim, Chang-Woo Lee, Eun-Hee Hong, Eun Ho Kim, Sang-Gu Hwang
Pages: 1565-1572
Published online on: 22 February 2018

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Article

Itraconazole inhibits invasion and migration of pancreatic cancer cells by suppressing TGF-β/SMAD2/3 signaling

Ke Chen, Liang Cheng, Weikun Qian, Zhengdong Jiang, Liankang Sun, Yanfei Zhao, Yongsheng Zhou, Lizhi Zhao, Pengli Wang, Wanxing Duan, Qingyong Ma, Wei Yang
Pages: 1573-1582
Published online on: 26 February 2018

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Article Open Access

REC8 inhibits EMT by downregulating EGR1 in gastric cancer cells

Junhong Zhao, Lanlan Geng, Gaoyang Duan, Wanfu Xu, Yang Cheng, Zhiliang Huang, Zhenwen Zhou, Sitang Gong
Pages: 1583-1590
Published online on: 01 February 2018

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Article Open Access

Long non-coding RNA XIST exerts oncogenic functions in pancreatic cancer via miR-34a-5p

Zhixia Sun, Baogang Zhang, Tingting Cui
Pages: 1591-1600
Published online on: 02 February 2018

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Article Open Access

Effect of sinomenine hydrochloride on radiosensitivity of esophageal squamous cell carcinoma cells

Shenbo Fu, Long Jin, Tuotuo Gong, Shupei Pan, Shuyu Zheng, Xuanwei Zhang, Tian Yang, Yuchen Sun, Ya Wang, Jia Guo, Beina Hui, Xiaozhi Zhang
Pages: 1601-1608
Published online on: 22 January 2018

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Article Open Access

Effects of low-intensity ultrasound combined with low-dose carboplatin in an orthotopic hamster model of tongue cancer: A preclinical study

Hai-Xia Li, Jin-Hua Zheng, Liang Ji, Guan-Yao Liu, Yv-Kun Lv, Dan Yang, Zheng Hu, He Chen, Feng-Min Zhang, Wenwu Cao
Pages: 1609-1618
Published online on: 13 February 2018

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Article Open Access

Downregulation of the long non-coding RNA XLOC_010588 inhibits the invasion and migration of colorectal cancer

Yue Li, Lin Zhao, Yining Zhang, Lin Guan, Huijing Zhang, Huan Zhou, Tong Gao, Peng Miao, Mingjun Sun
Pages: 1619-1630
Published online on: 12 February 2018

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Article Open Access

miR-181 regulates cisplatin-resistant non-small cell lung cancer via downregulation of autophagy through the PTEN/PI3K/AKT pathway

Jiangang Liu, Yingru Xing, Ling Rong
Pages: 1631-1639
Published online on: 13 February 2018

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Article Open Access

Short hairpin RNA-mediated gene silencing of ADAM17 inhibits the growth of breast cancer MCF‑7 cells in vitro and in vivo and its mechanism of action

Baoshan Hu, Xiangchao Meng, Yan Zhang, Mohammad Monir Hossain, Lijun Wu, Yuanyuan Zhang, Xiaobing Peng, Xuepeng Zhang
Pages: 1640-1648
Published online on: 26 January 2018

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Article Open Access

miR-199a-3p enhances cisplatin sensitivity of ovarian cancer cells by targeting ITGB8

Yajie Cui, Fengqin Wu, Defu Tian, Ting Wang, Tianjie Lu, Xiying Huang, Peilian Zhang, Li Qin
Pages: 1649-1657
Published online on: 12 February 2018

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Article Open Access

miR-195 inhibits cell proliferation and angiogenesis in human prostate cancer by downregulating PRR11 expression Corrigendum in /10.3892/or.2023.8507

Chao Cai, Huichan He, Xiaolu Duan, Wenqi Wu, Zanlin Mai, Tao Zhang, Junhong Fan, Tuo Deng, Wen Zhong, Yongda Liu, Weide Zhong, Guohua Zeng
Pages: 1658-1670
Published online on: 31 January 2018

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Article Open Access

Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy Retraction in /10.3892/or.2024.8767

Hongzhu Yan, Chengmin Qiu, Weiwei Sun, Minmin Gu, Feng Xiao, Jue Zou, Li Zhang
Pages: 1671-1681
Published online on: 07 February 2018

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Article Open Access

Prognostic and predictive value of HURP in non‑small cell lung cancer

Qi Wang, Yaokun Chen, Hui Feng, Biyuan Zhang, Haiji Wang
Pages: 1682-1692
Published online on: 26 February 2018

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Article Open Access

High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Pages: 1693-1701
Published online on: 16 February 2018

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Article

Polygalacin D induces apoptosis and cell cycle arrest via the PI3K/Akt pathway in non-small cell lung cancer

Yun-Soo Seo, Ok-Hwa Kang, Ryong Kong, Tian Zhou, Sang-A Kim, Shiyong Ryu, Hak-Ryul Kim, Dong-Yeul Kwon
Pages: 1702-1710
Published online on: 23 January 2018

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Article

Anti-angiogenic and pro-apoptotic effects of a small-molecule JFD-WS in in vitro and breast cancer xenograft mouse models

Appu Rathinavelu, Thanigaivelan Kanagasabai, Sivanesan Dhandayuthapani , Khalid Alhazzani
Pages: 1711-1724
Published online on: 09 February 2018

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Article

Aurora-A overexpression is linked to development of aggressive teratomas derived from human iPS cells

Seiga Ohmine, Jeffrey L. Salisbury, James Ingle, Giuseppe Pettinato, Candace L. Haddox, Tufia Haddad, Evanthia Galanis, Yasuhiro Ikeda, Antonino B. D'assoro
Pages: 1725-1730
Published online on: 31 January 2018

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Article

Puerarin inhibits non-small cell lung cancer cell growth via the induction of apoptosis

Yefang Hu, Xi Li, Ling Lin, Siting Liang, Jian Yan
Pages: 1731-1738
Published online on: 26 January 2018

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Article

Knockdown of angiopoietin-like 4 inhibits the development of human gastric cancer

Jin-Wu Chen, Ying-Jia Luo, Zheng-Fei Yang, Li-Qiang Wen, Lin Huang
Pages: 1739-1746
Published online on: 07 February 2018

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Article

Inhibition of MUS81 improves the chemical sensitivity of olaparib by regulating MCM2 in epithelial ovarian cancer

Ailing Zhong, Hongqin Zhang, Suhong Xie, Minjie Deng, Hui Zheng, Yanchun Wang, Miaomiao Chen, Renquan Lu, Lin Guo
Pages: 1747-1756
Published online on: 22 January 2018

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Article

Vandetanib inhibits cisplatin‑resistant neuroblastoma tumor growth and invasion

Changchun Li, Chao Yang, Guanghui Wei
Pages: 1757-1764
Published online on: 09 February 2018

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Article

Mechanism of ECM-induced dormancy and chemoresistance in A549 human lung carcinoma cells

Siriporn Keeratichamroen, Kriengsak Lirdprapamongkol, Jisnuson Svasti
Pages: 1765-1774
Published online on: 12 February 2018

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Article

The targeted inhibition of Hsp90 by a synthetic small molecule, DPide offers an effective treatment strategy against TNBCs

Yong Jin Oh, Sun You Park, Young Ho Seo
Pages: 1775-1782
Published online on: 07 February 2018

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Article

Sensitivity to chemotherapeutics of NSCLC cells with acquired resistance to EGFR-TKIs is mediated by T790M mutation or epithelial-mesenchymal transition

Juan Zhou, Qiaoting Hu, Xi Zhang, Jihua Zheng, Bo Xie, Zhiyong Xu, Weimin Zhang
Pages: 1783-1792
Published online on: 01 February 2018

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Article

Secretory leukocyte peptidase inhibitor expression and apoptosis effect in oral leukoplakia and oral squamous cell carcinoma

Xin Wang, Yu Jin, Yue-Xiu Li, Ya Yang
Pages: 1793-1804
Published online on: 07 February 2018

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Article

Autophagy‑mediated adaptation of hepatocellular carcinoma cells to hypoxia‑mimicking conditions constitutes an attractive therapeutic target

Satoshi Owada, Hitoshi Endo, Yukari Shida, Chisa Okada, Kanako Ito, Takahiro Nezu, Masayuki Tatemichi
Pages: 1805-1812
Published online on: 23 February 2018

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Article

Differentially expressed circRNAs in melanocytes and melanoma cells and their effect on cell proliferation and invasion

Qi Wang, Jia Chen, Aijun Wang, Lichun Sun, Li Qian, Xiao Zhou, Yu Liu, Shijie Tang, Xiang Chen, Yan Cheng, Ke Cao, Jianda Zhou
Pages: 1813-1824
Published online on: 13 February 2018

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Article

MicroRNA-375 inhibits glioma cell proliferation and migration by downregulating RWDD3 in vitro Retraction in /10.3892/or.2020.7738

Chen-Xing Ji, Yang-Hua Fan, Fan Xu, Shi-Gang Lv, Min-Hua Ye, Miao-Jing Wu, Xin-Gen Zhu, Lei Wu
Pages: 1825-1834
Published online on: 13 February 2018

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Article

Syndecan-1 suppresses epithelial-mesenchymal transition and migration in human oral cancer cells

Xiaofeng Wang, Jinting He, Xiaoming Zhao, Tianyang Qi, Tianfu Zhang, Chenfei Kong
Pages: 1835-1842
Published online on: 14 February 2018

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Article

Knockdown of EPCR inhibits the proliferation and migration of human gastric cancer cells via the ERK1/2 pathway in a PAR-1-dependent manner

Qingling Wang, Hongli Yang, Qian Zhuo, Yanyan Xu, Peng Zhang
Pages: 1843-1852
Published online on: 21 February 2018

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Article

FNDC3B promotes epithelial-mesenchymal transition in tongue squamous cell carcinoma cells in a hypoxic microenvironment Corrigendum in /10.3892/or.2020.7744 Corrigendum in /10.3892/or.2021.8067

Zhaoming Zhong, Hongxing Zhang, Min Hong, Chuanzheng Sun, Yuanyuan Xu, Xiao Chen, Change Gao, Minjie He, Weiqing Liu, Jin Liang
Pages: 1853-1859
Published online on: 24 January 2018

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Article

TRIM28 promotes cervical cancer growth through the mTOR signaling pathway

Fan Li, Zhijie Wang, Gaochuan Lu
Pages: 1860-1866
Published online on: 26 January 2018

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Article

β‑carotene reverses tobacco smoke‑induced gastric EMT via Notch pathway in vivo

Ling Lu, Jia Chen, Manli Li, Ling Tang, Rui Wu, Longtao Jin, Zhaofeng Liang
Pages: 1867-1873
Published online on: 02 February 2018

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Article

Transdifferentiation of type II alveolar epithelial cells induces reactivation of dormant tumor cells by enhancing TGF-β1/SNAI2 signaling

Yuanhong Zhou, Qiang Liu, Xiangchen Dai, Yuling Yan, Ying Yang, Hua Li, Xiaoling Zhou, Wenqi Gao, Xiaolan Li, Zuyang Xi
Pages: 1874-1882
Published online on: 06 February 2018

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Article

Saffron carotenoids inhibit STAT3 activation and promote apoptotic progression in IL-6-stimulated liver cancer cells Corrigendum in /10.3892/or.2024.8727

Buyun  Kim, Byoungduck Park
Pages: 1883-1891
Published online on: 25 January 2018

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Article

Tyrphostin B42 attenuates trichostatin A-mediated resistance in pancreatic cancer cells by antagonizing IL-6/JAK2/STAT3 signaling

Xing Zhang, Hong Lu, Weilong Hong, Leping Liu, Silu Wang, Mengtao Zhou, Bicheng Chen, Yongheng Bai
Pages: 1892-1900
Published online on: 31 January 2018

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Article

PARP1-siRNA suppresses human prostate cancer cell growth and progression

Yongchang Lai, Zhenzhen Kong, Tao Zeng, Shaohong Xu, Xiaolu Duan, Shujue Li, Chao Cai, Zhijian Zhao, Wenqi Wu
Pages: 1901-1909
Published online on: 26 January 2018

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Article

TRIB2 knockdown as a regulator of chemotherapy resistance and proliferation via the ERK/STAT3 signaling pathway in human chronic myelogenous leukemia K562/ADM cells

Xiancheng Ma, Xue Zhou, Haiyan Qu, Ying Ma, Zhen Yue, Wenjing Shang, Pingyu Wang, Shuyang Xie, Youjie Li, Yunxiao Sun
Pages: 1910-1918
Published online on: 07 February 2018

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Article

Fatostatin suppresses growth and enhances apoptosis by blocking SREBP-regulated metabolic pathways in endometrial carcinoma

Shuhong Gao, Zhengzheng Shi, Xin Li, Wenzhi Li, Yiling Wang, Zhiming Liu, Jie Jiang
Pages: 1919-1929
Published online on: 13 February 2018

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Article

Kynurenine promotes the goblet cell differentiation of HT-29 colon carcinoma cells by modulating Wnt, Notch and AhR signals

Joo-Hung Park, Jeong-Min Lee, Eun-Jin Lee, Da-Jeong Kim, Won-Bhin Hwang
Pages: 1930-1938
Published online on: 13 February 2018

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Article

miRNA-320a inhibits glioma cell invasion and migration by directly targeting aquaporin 4

Wei Xiong, Jianhua Ran, Rong Jiang, Pei Guo, Xueping Shi, Haixing Li, Xiaoting Lv, Jing Li, Dilong Chen
Pages: 1939-1947
Published online on: 20 February 2018

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Article

lncRNA NEAT1 promotes cell proliferation and invasion by regulating miR‑365/RGS20 in oral squamous cell carcinoma

Gang Huang, Xin He, Xin‑Li Wei
Pages: 1948-1956
Published online on: 26 February 2018

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Article

Metformin facilitates BG45‑induced apoptosis via an anti‑Warburg effect in cholangiocarcinoma cells Corrigendum in /10.3892/or.2019.7111

Dehua Tang, Lei Xu, Mingming Zhang, Robert Gregory Dorfman, Yida Pan, Qian Zhou, Lixing Zhou, Yuming Wang, Yang Li, Yuyao Yin, Lei Wang, Xiaoping Zou
Pages: 1957-1965
Published online on: 20 February 2018

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Article

Raf1 is a prognostic factor for progression in patients with non‑small cell lung cancer after radiotherapy

Hao  Tian, Li  Yin, Kai  Ding, You‑You  Xia, Xiao‑Hong  Wang, Jian‑Zhong  Wu, Xia He
Pages: 1966-1974
Published online on: 22 February 2018

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Article

Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway

Jun Song, Sai-Jun Ma, Jian-Hua Luo, Hui Zhang, Ri-Xiong Wang, Hui Liu, Li Li, Zhi-Guang Zhang, Rui-Xiang Zhou
Pages: 1975-1983
Published online on: 26 February 2018

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Article

Co-treatment with gemcitabine and nab-paclitaxel exerts additive effects on pancreatic cancer cell death

Ilaria Passacantilli, Valentina Panzeri, Francesca Terracciano, Gianfranco Delle Fave, Claudio Sette, Gabriele Capurso
Pages: 1984-1990
Published online on: 25 January 2018

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Article

Combination of salinomycin and radiation effectively eliminates head and neck squamous cell carcinoma cells in vitro

Thomas Gehrke, Stephan Hackenberg, Bülent Polat, Gisela Wohlleben, Rudolf Hagen, Norbert Kleinsasser, Agmal Scherzad
Pages: 1991-1998
Published online on: 13 February 2018

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Article

Synergistic antitumor effects of histone deacetylase inhibitor scriptaid and bortezomib against ovarian cancer cells

Karolina Janyst, Michał Janyst, Marta Siernicka, Witold Lasek
Pages: 1999-2005
Published online on: 06 February 2018

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Article

β3GnT8 regulates oxaliplatin resistance by altering integrin β1 glycosylation in colon cancer cells

Li Shen, Xiaoxia Dong, Yingying Wang, Li Qiu, Feng Peng, Zhiguo Luo
Pages: 2006-2014
Published online on: 01 February 2018

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Article

Synergistic effect of metformin and medroxyprogesterone 17‑acetate on the development of endometrial cancer

Nan Mu, Mei Dong, Lei Li, Min Xia, Luyun Qv, Yingmei Wang, Changyan Dong, Yonghua Chen, Ying Zuo, Jianqing Hou, Fengxia Xue
Pages: 2015-2021
Published online on: 26 January 2018

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Article

CXCR4 receptor blockage reduces the contribution of tumor and stromal cells to the metastatic growth in the liver

Aitor Benedicto, Irene Romayor, Beatriz Arteta
Pages: 2022-2030
Published online on: 08 February 2018

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Article

High expression of TRAIL by osteoblastic differentiated dental pulp stem cells affects myeloma cell viability

Giacomina Brunetti, Adriana Di Benedetto, Francesca Posa, Graziana Colaianni, Maria Felicia Faienza, Andrea Ballini, Silvia Colucci, Giovanni Passeri, Lorenzo Lo Muzio, Maria Grano, Giorgio Mori
Pages: 2031-2039
Published online on: 15 February 2018

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Article

MicroRNA-655 attenuates the malignant biological behaviours of retinoblastoma cells by directly targeting PAX6 and suppressing the ERK and p38 MAPK signalling pathways Retraction in /10.3892/or.2022.8385

Min Zhang, Qiongxia Li, Yingzhe Pan, Hui Wang, Gang Liu, Hui Yin
Pages: 2040-2050
Published online on: 13 February 2018

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Correction Open Access

[Corrigendum] Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications

Xiang Y. Gao, Lin Li, Xiao H. Wang, Xian Z. Wen, Ke Ji, Lin Ye, Jun Cai, Wen G. Jiang, Jia F. Ji
Pages: 2051-2051
Published online on: 14 February 2018

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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