|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2017. CA Cancer J Clin. 67:7–30. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Wu Z, Wei D, Gao W, Xu Y, Hu Z, Ma Z, Gao
C, Zhu X and Li Q: TPO-induced metabolic reprogramming drives liver
metastasis of colorectal cancer CD110+ tumor-initiating cells. Cell
Stem Cell. 17:47–59. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Renault F, Formstecher E, Callebaut I,
Junier MP and Chneiweiss H: The multifunctional protein PEA-15 is
involved in the control of apoptosis and cell cycle in astrocytes.
Biochem Pharmacol. 66:1581–1588. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Danziger N, Yokoyama M, Jay T, Cordier J,
Glowinski J and Chneiweiss H: Cellular expression, developmental
regulation, and phylogenic conservation of PEA-15, the astrocytic
major phosphoprotein and protein kinase C substrate. J Neurochem.
64:1016–1025. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Farina B, Doti N, Pirone L, Malgieri G,
Pedone EM, Ruvo M and Fattorusso R: Molecular basis of the
PED/PEA15 interaction with the C-terminal fragment of phospholipase
D1 revealed by NMR spectroscopy. Biochim Biophys Acta.
1834:1572–1580. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Nagarajan A, Dogra SK, Liu AY, Green MR
and Wajapeyee N: PEA15 regulates the DNA damage-induced cell cycle
checkpoint and oncogene-directed transformation. Mol Cell Biol.
34:2264–2282. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Fiory F, Formisano P, Perruolo G and
Beguinot F: Frontiers: PED/PEA-15, a multifunctional protein
controlling cell survival and glucose metabolism. Am J Physiol
Endocrinol Metab. 297:E592–E601. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Mace PD, Wallez Y, Egger MF, Dobaczewska
MK, Robinson H, Pasquale EB and Riedl SJ: Structure of ERK2 bound
to PEA-15 reveals a mechanism for rapid release of activated MAPK.
Nat Commun. 4:16812013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Quintavalle C, Hindupur SK, Quagliata L,
Pallante P, Nigro C, Condorelli G, Andersen JB, Tagscherer KE, Roth
W, Beguinot F, et al: Phosphoprotein enriched in diabetes
(PED/PEA15) promotes migration in hepatocellular carcinoma and
confers resistance to sorafenib. Cell Death Dis. 8:e31382017.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Zanca C, Garofalo M, Quintavalle C, Romano
G, Acunzo M, Ragno P, Montuori N, Incoronato M, Tornillo L,
Baumhoer D, et al: PED is overexpressed and mediates TRAIL
resistance in human non-small cell lung cancer. J Cell Mol Med.
12:2416–2426. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Shin M, Lee KE, Yang EG, Jeon H and Song
HK: PEA-15 facilitates EGFR dephosphorylation via ERK sequestration
at increased ER-PM contacts in TNBC cells. FEBS Lett.
589:1033–1039. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Bartholomeusz C, Rosen D, Wei C, Kazansky
A, Yamasaki F, Takahashi T, Itamochi H, Kondo S, Liu J and Ueno NT:
PEA-15 induces autophagy in human ovarian cancer cells and is
associated with prolonged overall survival. Cancer Res.
68:9302–9310. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Pinato DJ, Tan TM, Toussi ST, Ramachandran
R, Martin N, Meeran K, Ngo N, Dina R and Sharma R: An expression
signature of the angiogenic response in gastrointestinal
neuroendocrine tumours: Correlation with tumour phenotype and
survival outcomes. Br J Cancer. 110:115–122. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression date using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Method. 25:402–408. 2001.
View Article : Google Scholar
|
|
16
|
Li F and Mahato RI: RNA interference for
improving the outcome of islet transplantation. Adv Drug Deliv Rev.
63:47–68. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Sotelo J, Esposito D, Duhagon MA, Banfield
K, Mehalko J, Liao H, Stephens RM, Harris TJ, Munroe DJ and Wu X:
Long-range enhancers on 8q24 regulate c-Myc. Proc Natl Acad Sci
USA. 107:3001–3005. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Urosevic J, Garcia-Albéniz X, Planet E,
Real S, Céspedes MV, Guiu M, Fernandez E, Bellmunt A, Gawrzak S,
Pavlovic M, et al: Colon cancer cells colonize the lung from
established liver metastases through p38 MAPK signalling and PTHLH.
Nat Cell Biol. 16:685–694. 2014. View
Article : Google Scholar : PubMed/NCBI
|
|
19
|
Loboda A, Nebozhyn MV, Watters JW, Buser
CA, Shaw PM, Huang PS, Van't Veer L, Tollenaar RA, Jackson DB,
Agrawal D, et al: EMT is the dominant program in human colon
cancer. BMC Med Genomics. 4:92011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Formisano P, Ragno P, Pesapane A, Alfano
D, Alberobello AT, Rea VE, Giusto R, Rossi FW, Beguinot F, Rossi G
and Montuori N: PED/PEA-15 interacts with the 67 kD laminin
receptor and regulates cell adhesion, migration, proliferation and
apoptosis. J Cell Mol Med. 16:1435–1446. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Mor A and Philips MR: Compartmentalized
Ras/MAPK signaling. Annu Rev Immunol. 24:771–800. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Fang JY and Richardson BC: The MAPK
signalling pathways and colorectal cancer. Lancet Oncol. 6:322–327.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Gu Y, Wang Q, Guo K, Qin W, Liao W, Wang
S, Ding Y and Lin J: TUSC3 promotes colorectal cancer progression
and epithelial-mesenchymal transition (EMT) through WNT/β-catenin
and MAPK signalling. J Pathol. 239:60–71. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lee J, Bartholomeusz C, Krishnamurthy S,
Liu P, Saso H, Lafortune TA, Hortobagyi GN and Ueno NT: PEA-15
unphosphorylated at both serine 104 and serine 116 inhibits ovarian
cancer cell tumorigenicity and progression through blocking
β-catenin. Oncogenesis. 1:e222012. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Sulzmaier F, Opoku-Ansah J and Ramos JW:
Phosphorylation is the switch that turns PEA-15 from tumor
suppressor to tumor promoter. Small GTPases. 3:173–177. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Eckert A, Böck BC, Tagscherer KE, Haas TL,
Grund K, Sykora J, Herold-Mende C, Ehemann V, Hollstein M,
Chneiweiss H, et al: The PEA-15/PED protein protects glioblastoma
cells from glucose deprivation-induced apoptosis via the ERK/MAP
kinase pathway. Oncogene. 27:1155–1166. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Li X, Iomini C, Hyink D and Wilson PD:
PRKX critically regulates endothelial cell proliferation,
migration, and vascular-like structure formation. Dev Biol.
356:475–485. 2011. View Article : Google Scholar : PubMed/NCBI
|
