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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-2019 Volume 41 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Progress of immune checkpoint therapy in the clinic (Review)

Yiqun Fan, Chi Zhang, Shengjie Jin, Zhihui Gao, Jun Cao, Aoqing Wang, Dawei Li, Qian Wang, Xing Sun, Dousheng Bai
Pages: 3-14
Published online on: 24 October 2018

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Article Open Access

Long non-coding RNA LOC285194 functions as a tumor suppressor by targeting p53 in non-small cell lung cancer

Huaping Zhou, Allen Chen, Jianfei Shen, Xiaoxue Zhang, Min Hou, Jin Li, Jingyi Chen, Huan Zou, Yingfei Zhang, Qianren Deng, Kelin She, Xiaoshun Shi, Jianxing He
Pages: 15-26
Published online on: 31 October 2018

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Article Open Access

Antitumor effects of arsenic disulfide on the viability, migratory ability, apoptosis and autophagy of breast cancer cells Corrigendum in /10.3892/or.2020.7653

Yuxue Zhao, Kenji Onda, Kentaro Sugiyama, Bo Yuan, Sachiko Tanaka, Norio Takagi, Toshihiko Hirano
Pages: 27-42
Published online on: 09 October 2018

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Article Open Access

PEA15 promotes liver metastasis of colorectal cancer by upregulating the ERK/MAPK signaling pathway Retraction in /10.3892/or.2023.8574

Bo Tang, Wenjin Liang, Yong Liao, Zeming Li, Yan Wang, Chao Yan
Pages: 43-56
Published online on: 25 October 2018

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Article Open Access

Downregulation of miR‑505‑3p predicts poor bone metastasis‑free survival in prostate cancer

Yubo Tang, Bowen Wu, Shuai Huang, Xinsheng Peng, Xing Li, Xiufang Huang, Wei Zhou, Peigen Xie, Peiheng He
Pages: 57-66
Published online on: 25 October 2018

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Article Open Access

Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer Corrigendum in /10.3892/or.2025.9013

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Pages: 67-76
Published online on: 24 October 2018

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Article Open Access

Osimertinib (AZD9291) increases radio‑sensitivity in EGFR T790M non‑small cell lung cancer

Nannan Wang, Linlin Wang, Xiangjiao Meng, Jia Wang, Lifang Zhu, Changting Liu, Shaorong Li, Li Zheng, Zhenfan Yang, Ligang Xing, Jinming Yu
Pages: 77-86
Published online on: 17 October 2018

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Article Open Access

The diagnostic value of circulating microRNAs as a biomarker for gastric cancer: A meta‑analysis

Hui Wei, Ke Pu, Xiao‑Guang Liu, Bo‑Xuan Li, Heng‑Shuo Zhang, Huan Wang, Hao Wang, Wei‑Ming Sun, Yu‑Ping Wang
Pages: 87-102
Published online on: 11 October 2018

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Article Open Access

Dendritic cell factor 1 inhibits proliferation and migration and induces apoptosis of neuroblastoma cells by inhibiting the ERK signaling pathway

Guanghong Luo, Ruili Feng, Yangyang Sun, Lili Zheng, Yajiang Wang, Yanlu Chen, Tieqiao Wen
Pages: 103-112
Published online on: 16 October 2018

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Article Open Access

A two‑circRNA signature predicts tumour recurrence in clinical non‑functioning pituitary adenoma

Jing Guo, Zhuang Wang, Yazhou Miao, Yutao Shen, Mingxuan Li, Lei Gong, Hongyun Wang, Yue He, Hua Gao, Qian Liu, Chuzhong Li, Yazhuo Zhang
Pages: 113-124
Published online on: 02 November 2018

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Article Open Access

PI3Kβ inhibitor AZD6482 exerts antiproliferative activity and induces apoptosis in human glioblastoma cells

Peng-Fei Xu, Ji-An Yang, Jun-Hui Liu, Xue Yang, Jian-Ming Liao, Fan-En Yuan, Bao-Hui Liu, Qian-Xue Chen
Pages: 125-132
Published online on: 02 November 2018

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Article Open Access

Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma

Sayaka Kobayashi, Masanao Saio, Toshio Fukuda, Kiminori Kimura, Junko Hirato, Tetsunari Oyama
Pages: 133-142
Published online on: 02 November 2018

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Article Open Access

Targeting LRH‑1 in hepatoblastoma cell lines causes decreased proliferation

Jingling Jin, Junliang Jin, Sarah E. Woodfield, Roma H. Patel, Nan Ge Jin, Yan Shi, Bin Liu, Wenjing Sun, Xiangmei Chen, Yang Yu, Sanjeev A. Vasudevan
Pages: 143-153
Published online on: 15 October 2018

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Article Open Access

High expression of TMEM40 contributes to progressive features of tongue squamous cell carcinoma

Qingyan Zhang, Danhui Huang, Zhenfei Zhang, Yuzhen Feng, Meiting Fu, Min Wei, Jueyu Zhou, Yuanjin Huang, Shuguang Liu, Rong Shi
Pages: 154-164
Published online on: 12 October 2018

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Article Open Access

RGS5 decreases the proliferation of human ovarian carcinoma‑derived primary endothelial cells through the MAPK/ERK signaling pathway in hypoxia

Dan Wang, Yan Xu, Lu Feng, Pin Yin, Shuang Shuang Song, Feng Wu, Ping Yan, Zhiqing Liang
Pages: 165-177
Published online on: 22 October 2018

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Article Open Access

Hypoxia increases chemoresistance in human medulloblastoma DAOY cells via hypoxia‑inducible factor 1α‑mediated downregulation of the CYP2B6, CYP3A4 and CYP3A5 enzymes and inhibition of cell proliferation

Jesús Valencia‑Cervantes, Sara Huerta‑Yepez, Guillermo Aquino‑Jarquín, Sara Rodríguez‑Enríquez, Daniel Martínez‑Fong, José‑Antonio Arias‑Montaño, Víctor Manuel Dávila‑Borja
Pages: 178-190
Published online on: 12 October 2018

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Article Open Access

GLIS2 redundancy causes chemoresistance and poor prognosis of gastric cancer based on co‑expression network analysis

Jingsheng Yuan, Lulu Tan, Zhijie Yin, Kaixiong Tao, Guobing Wang, Wenjia Shi, Jinbo Gao
Pages: 191-201
Published online on: 15 October 2018

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Article Open Access

Galla Rhois water extract inhibits lung metastasis by inducing AMPK‑mediated apoptosis and suppressing metastatic properties of colorectal cancer cells

Jeong‑Geon Mun, Ji‑Ye Kee, Yo‑Han Han, Sullim Lee, Seong‑Hwan Park, Hee Dong Jeon, Seung‑Heon Hong
Pages: 202-212
Published online on: 22 October 2018

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Article Open Access

Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway

Huan Yu, Qi‑Rui Fu, Zhi‑Jie Huang, Jia‑Yu Lin, Qing‑Xi Chen, Qin Wang, Dong‑Yan Shen
Pages: 213-223
Published online on: 29 October 2018

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Article Open Access

sFRP1 exerts effects on gastric cancer cells through GSK3β/Rac1‑mediated restraint of TGFβ/Smad3 signaling

Ji‑Xiang Peng, Shun‑Yu Liang, Li Li
Pages: 224-234
Published online on: 31 October 2018

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Article Open Access

Anoikis‑resistant human osteosarcoma cells display significant angiogenesis by activating the Src kinase‑mediated MAPK pathway

Ziran Gao, Guo‑Sheng Zhao, Yangfan Lv, Dongbin Peng, Xuefeng Tang, Hanxiang Song, Qiao‑Nan Guo
Pages: 235-245
Published online on: 29 October 2018

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Article Open Access

Bromodomain PHD‑finger transcription factor promotes glioma progression and indicates poor prognosis

Yanling Pan, Feng Yuan, Yijie Li, Guoping Wang, Zhiren Lin, Longhua Chen
Pages: 246-256
Published online on: 30 October 2018

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Article Open Access

Exosomal microRNAs as potential biomarkers for cancer cell migration and prognosis in hepatocellular carcinoma patient-derived cell models

Ling-Xiang Yu, Bo-Lun Zhang, Yuan Yang, Meng-Chao Wang, Guang-Lin Lei, Yuan Gao, Hu Liu, Chao-Hui Xiao, Jia-Jia Xu, Hao Qin, Xiao-Ya Xu, Zi-Shuo Chen, Da-Dong Zhang, Fu-Gen Li, Shao-Geng Zhang, Rong Liu
Pages: 257-269
Published online on: 29 October 2018

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Article Open Access

Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Pages: 270-278
Published online on: 02 November 2018

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Article Open Access

Identifying the key genes and microRNAs in colorectal cancer liver metastasis by bioinformatics analysis and in vitro experiments

Tao Zhang, Jianrong Guo, Jian Gu, Zheng Wang, Guobin Wang, Huili Li, Jiliang Wang
Pages: 279-291
Published online on: 01 November 2018

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Article

Identification of a 5‑microRNA signature and hub miRNA‑mRNA interactions associated with pancreatic cancer

Xianxiong Ma, Ruikang Tao, Lei Li, Hengyu Chen, Zongtao Liu, Jie Bai, Xiaoming Shuai, Chuanqing Wu, Kaixiong Tao
Pages: 292-300
Published online on: 24 October 2018

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Article

Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis

Junji Akagi, Hideo Baba
Pages: 301-311
Published online on: 01 November 2018

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Article

Peptides and small molecules blocking the CXCR4/CXCL12 axis overcome bone marrow‑induced chemoresistance in acute leukemias

Serena Pillozzi, Andrea Bernini, Ottavia Spiga, Barbara Lelli, Giulia Petroni, Luisa Bracci, Neri Niccolai, Annarosa Arcangeli
Pages: 312-324
Published online on: 18 October 2018

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Article

Histone methyltransferase SUV39H2 serves oncogenic roles in osteosarcoma

Lianhua Piao, Xiaofeng Yuan, Ming Zhuang, Xubin Qiu, Xiaoshuang Xu, Ren Kong, Zhiwei Liu
Pages: 325-332
Published online on: 01 November 2018

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Article Open Access

Licochalcone H induces the apoptosis of human oral squamous cell carcinoma cells via regulation of matrin 3

Su‑Hyun Nho, Goo Yoon, Ji‑Hye Seo, Ha‑Na Oh, Seung‑Sik Cho, Hangun Kim, Hyun Woo Choi, Jung‑Hyun Shim, Jung‑Il Chae
Pages: 333-340
Published online on: 11 October 2018

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Article

β‑blockers inhibit the viability of breast cancer cells by regulating the ERK/COX‑2 signaling pathway and the drug response is affected by ADRB2 single‑nucleotide polymorphisms

Wan‑Ying Xie, Ruo‑Hui He, Jun Zhang, Yi‑Jing He, Zan Wan, Cheng‑Fang Zhou, Yong‑Jun Tang, Zhi Li, Howard L. Mcleod, Jie Liu
Pages: 341-350
Published online on: 29 October 2018

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Article

MicroRNA‑494 promotes the proliferation and migration of human glioma cancer cells through the protein kinase B/mechanistic target of rapamycin pathway by phosphatase and tensin homolog expression

Kun Han, Zhao Jian Li, Peng Sun
Pages: 351-360
Published online on: 25 October 2018

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Article

Malignant gliomas can be converted to non‑proliferating glial cells by treatment with a combination of small molecules

Jinsoo Oh, Yongbo Kim, Daye Baek, Yoon Ha
Pages: 361-368
Published online on: 25 October 2018

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Article

Ginkgolic acid suppresses the invasion of HepG2 cells via downregulation of HGF/c‑Met signaling

Hua Li, Xiaofen Meng, Di Zhang, Xin Xu, Shunle Li, Yiming Li
Pages: 369-376
Published online on: 12 October 2018

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Article

miR‑101 regulates the cell proliferation and apoptosis in diffuse large B‑cell lymphoma by targeting MEK1 via regulation of the ERK/MAPK signaling pathway

Yiqun Huang, Yong Zou, Luhui Lin, Xudong Ma, Ruiji Zheng
Pages: 377-386
Published online on: 24 October 2018

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Article

Effects of green tea, matcha tea and their components epigallocatechin gallate and quercetin on MCF‑7 and MDA-MB-231 breast carcinoma cells Corrigendum in /10.3892/or.2019.7430

Lennard Schröder, Philip Marahrens, Julian G. Koch, Helene Heidegger, Theresa Vilsmeier, Thuy Phan-Brehm, Simone Hofmann, Sven Mahner, Udo Jeschke, Dagmar U. Richter
Pages: 387-396
Published online on: 12 October 2018

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Article

Intraocular involvement is associated with a high risk of disease relapse in primary central nervous system lymphoma

Lin Zhuang, Jie Lai, Kun Chen, Tianling Ding, Yan Yuan, Yan Ma, Hui Kang, Zhiguang Lin, Ni Fan, Jingjing Ma, Qingchao Zeng, Xiaoping Xu, Qingping Wang, Bobin Chen
Pages: 397-404
Published online on: 11 October 2018

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Article

Metformin suppresses gastric cancer progression through calmodulin‑like protein 3 secreted from tumor‑associated fibroblasts

Guangxia Chen, Chenxiao Yu, Zhicheng Tang, Shiyu Liu, Fangmei An, Junjia Zhu, Qianqian Wu, Jianping Cao, Qiang Zhan, Shuyu Zhang
Pages: 405-414
Published online on: 11 October 2018

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Article

Mechanisms underlying the increased chemosensitivity of bortezomib-resistant multiple myeloma by silencing nuclear transcription factor Snail1

Zhenqi Huang, Xinglin Liang, Wei Wu, Xiaowen Chen, Qingshu Zeng, Mingzhen Yang, Jian Ge, Ruixiang Xia
Pages: 415-426
Published online on: 16 October 2018

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Article

I157172, a novel inhibitor of cystathionine γ-lyase, inhibits growth and migration of breast cancer cells via SIRT1-mediated deacetylation of STAT3

Lupeng Wang, Haimei Shi, Xiaoyu Zhang, Xiuli Zhang, Ya Liu, Wenyi Kang, Xiaoyan Shi, Tianxiao Wang
Pages: 427-436
Published online on: 16 October 2018

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Article

Signaling pathway inhibitors target breast cancer stem cells in triple-negative breast cancer

Wenlong Li, Hongmei Yang, Xiaoli Li, Lou Han, Ning Xu, Aiping Shi
Pages: 437-446
Published online on: 18 October 2018

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Article

Non‑invasive monitoring of cisplatin and erlotinib efficacy against lung cancer in orthotopic SCID mouse models by small animal FDG‑PET/CT and CT

Tamaki Otani, Kazuya Kondo, Hiromitsu Takizawa, Koichiro Kajiura, Haruhiko Fujino, Hideki Otsuka, Hirokazu Miyoshi
Pages: 447-454
Published online on: 24 October 2018

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Article

Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao‑Xia Li, Liang Shi, Jing Wu, Jia‑Yi Qian, Tian‑Song Xia, Wen‑Bin Zhou, Xi Sun, Xu‑Jie Zhou, Ji‑Fu Wei, Qiang Ding
Pages: 455-464
Published online on: 01 November 2018

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Article

Fascin is involved in cancer cell invasion and is regulated by stromal factors

Xianglan Zhang, Il‑Hoon Cho, Ji Hyeon Park, Min Kyeong Lee, Young Sun Hwang
Pages: 465-474
Published online on: 02 November 2018

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Article

Induction of apoptosis and erythroid differentiation of human chronic myelogenous leukemia K562 cells by low concentrations of lidamycin

Chu Zhang, Lu-Ying Guo, Dan Mu, Jian-Hua Gong, Jing Chen
Pages: 475-482
Published online on: 02 November 2018

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Article

Long non‑coding RNA ENST00000547547 inhibits cell proliferation, invasion and migration in colorectal cancer cells

Xiaohui Ai, Qingliang Lei, Xiaoping Shen, Jian Li, Chaoqun Cen, Gang Xie, Bo Luo, Wenshuo Zhu, Gui Hu, Hao Wu, Miao Chen, Xiaorong Li, Changwei Lin
Pages: 483-491
Published online on: 31 October 2018

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Article

Inhibition of autophagy enhances cinobufagin‑induced apoptosis in gastric cancer

Xuanxuan Xiong, Bo Lu, Qingzhong Tian, Haiyan Zhang, Mingbo Wu, Hao Guo, Qianjin Zhang, Xiangcheng Li, Tian Zhou, Yun Wang
Pages: 492-500
Published online on: 31 October 2018

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Article

In vitro neutralization of autocrine IL‑10 affects Op18/stathmin signaling in non‑small cell lung cancer cells

Yan Zhao, Sangyan Chen, Fang Shen, Dan Long, Ting Yu, Mengru Wu, Xuechi Lin
Pages: 501-511
Published online on: 15 October 2018

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Article

Two prostate cancer‑associated polymorphisms in the 3'UTR of IGF1R influences prostate cancer susceptibility by affecting miRNA binding Corrigendum in /10.3892/or.2020.7646

Huimin Wang, Wentao Huang, Xiaoxiang Yu, Weidong Li, Yuanjie Huang, Zengnan Mo, Yong Gao, Qingniao Zhou, Yanling Hu
Pages: 512-524
Published online on: 22 October 2018

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Article

Vorinostat enhances gefitinib‑induced cell death through reactive oxygen species‑dependent cleavage of HSP90 and its clients in non‑small cell lung cancer with the EGFR mutation

Sang Eun Park, Dong Eun Kim, Mi Joung Kim, Jee Suk Lee, Jin Kyung Rho, Seong‑Yun Jeong, Eun Kyung Choi, Choung‑Soo Kim, Jung Jin Hwang
Pages: 525-533
Published online on: 22 October 2018

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Article

Affibody‑mediated imaging of EGFR expression in prostate cancer using radiocobalt‑labeled DOTA‑ZEGFR:2377

Bogdan Mitran, Ken Gösta Andersson, Elin Lindström, Javad Garousi, Maria  Rosestedt, Vladimir Tolmachev, Stefan Ståhl, Anna Orlova, John Löfblom
Pages: 534-542
Published online on: 15 October 2018

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Article

Ubiquitin‑specific protease 7 promotes osteosarcoma cell metastasis by inducing epithelial‑mesenchymal transition

Qiuming Zeng, Zongyuan Li, Xi Zhao, Liang Guo, Chao Yu, Jun Qin, Shiqiong Zhang, Yongle Zhang, Xuhui Yang
Pages: 543-551
Published online on: 31 October 2018

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Article

BRMS1 participates in regulating cell sensitivity to DNA interstrand crosslink damage by interacting with FANCI

Jianming Dou, Yiren Zhou, Xuni Liu, Xiaojing Qiao, Xi Yang, Wenjuan Xie, Shouyi Qiao, Yanhua Wu
Pages: 552-558
Published online on: 24 October 2018

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Article

Downregulation of cyclooxygenase‑1 stimulates mitochondrial apoptosis through the NF‑κB signaling pathway in colorectal cancer cells

Lei Ding, Huan Gu, Zhenwei Lan, Qingchun Lei, Wenxue Wang, Jiangfei Ruan, Min Yu, Jie Lin, Qinghua Cui
Pages: 559-569
Published online on: 12 October 2018

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Article

E26 transformation (ETS)‑specific related transcription factor‑3 (ELF3) orchestrates a positive feedback loop that constitutively activates the MAPK/Erk pathway to drive thyroid cancer

Heming Chen, Weihong Chen, Xiaojun Zhang, Lin Hu, Guojun Tang, Juan Kong, Zhiwei Wang
Pages: 570-578
Published online on: 18 October 2018

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Article

SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB

Ming Zhou, Aman Wang, Baosheng Yin, Dan Wu, Shiliang Han, Wenpeng Zhang, Jiwei Liu, Kang Sun
Pages: 579-589
Published online on: 24 October 2018

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Article

Phosphorylation of nucleolin is indispensable to its involvement in the proliferation and migration of non-small cell lung cancer cells

Feifei Huang, Yanyang Wu, Hong Tan, Tianyao Guo, Ke Zhang, Daiqiang Li, Zhongyi Tong
Pages: 590-598
Published online on: 12 October 2018

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MicroRNA‑301a targets WNT1 to suppress cell proliferation and migration and enhance radiosensitivity in esophageal cancer cells

Huafang Su, Youyi Wu, Ya Fang, Lanxiao Shen, Zhenghua Fei, Congying Xie, Ming Chen
Pages: 599-607
Published online on: 16 October 2018

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CCL9/CCR1 induces myeloid‑derived suppressor cell recruitment to the spleen in a murine H22 orthotopic hepatoma model

Baohua Li, Shu Zhang, Na Huang, Haiyan Chen, Peijun Wang, Jun Yang, Zongfang Li
Pages: 608-618
Published online on: 18 October 2018

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MicroRNA-296 inhibits colorectal cancer cell growth and enhances apoptosis by targeting ARRB1-mediated AKT activation

Zhe Zhang, Xiaohua Zhong, Yipin Xiao, Chao Chen
Pages: 619-629
Published online on: 18 October 2018

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COL‑3 enhances the anti‑proliferative and pro‑apoptotic effects of paclitaxel in breast cancer cells

Roba M. El‑Tabba', Princy Mathew, Willias Masocha, Maitham A. Khajah
Pages: 630-642
Published online on: 22 October 2018

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OBP‑801, a novel histone deacetylase inhibitor, induces M‑phase arrest and apoptosis in rhabdomyosarcoma cells Corrigendum in /10.3892/or.2019.6997

Chihiro Tomoyasu, Ken Kikuchi, Daisuke Kaneda, Shigeki Yagyu, Mitsuru Miyachi, Kunihiko Tsuchiya, Tomoko Iehara, Toshiyuki Sakai, Hajime Hosoi
Pages: 643-649
Published online on: 22 October 2018

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Curcumin attenuates hyperglycemia-driven EGF-induced invasive and migratory abilities of pancreatic cancer via suppression of the ERK and AKT pathways

Wei Li, Zheng Wang, Xue Xiao, Liang Han, Zheng Wu, Qingyong Ma, Lei Cao
Pages: 650-658
Published online on: 30 October 2018

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Article

Identification of biomarkers for the prediction of relapse‑free survival in pediatric B‑precursor acute lymphoblastic leukemia

Wei Jing, Jing Li
Pages: 659-667
Published online on: 02 November 2018

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SMAD specific E3 ubiquitin protein ligase 1 promotes ovarian cancer cell migration and invasion via the activation of the RhoA/ROCK signaling pathway Retraction in /10.3892/or.2025.8938

Wei Wang, Han Du, Huiping Liu, Fangfang Hu, Guangzhi Liu
Pages: 668-676
Published online on: 31 October 2018

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Inhibitory effects of Schisandrin B on human prostate cancer cells

Moussa Ide Nasser, Tingyu Han, Salah Adlat, Yuxin Tian, Nan Jiang
Pages: 677-685
Published online on: 15 October 2018

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Article

Oncolytic cancer therapy with a vaccinia virus strain

Lili Deng, Jun Fan, Yuedi Ding, Jue Zhang, Bin Zhou, Yi Zhang, Biao Huang, Zhigang Hu
Pages: 686-692
Published online on: 16 October 2018

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Novel 2,3‑disubstituted 1,3‑thiazolidin‑4‑one derivatives as potential antitumor agents in renal cell adenocarcinoma

Monika Gawrońska‑Grzywacz, Łukasz Popiołek, Dorota Natorska‑Chomicka, Iwona Piątkowska‑Chmiel, Magdalena Izdebska, Mariola Herbet, Magdalena Iwan, Agnieszka Korga, Jarosław Dudka, Monika Wujec
Pages: 693-701
Published online on: 16 October 2018

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MicroRNA‑876‑5p inhibits the progression of glioblastoma multiforme by directly targeting Forkhead box M1 Retraction in /10.3892/or.2022.8360

Lina Wang, Jia Lu, Hong Zhang, Xueman Lyu, Zhigang Sun
Pages: 702-710
Published online on: 17 October 2018

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Article

Anticancer activity of gomisin J from Schisandra chinensis fruit

Samil Jung, Hyung-In Moon, Subeen Kim, Nguyen Thi Ngoc Quynh, Jimin Yu, Zolzaya Sandag, Dan-Diem Thi Le, Hyegyeong Lee, Hyojeong Lee, Myeong-Sok Lee
Pages: 711-717
Published online on: 02 November 2018

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Correction Open Access

[Corrigendum] Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKT inhibitor MK2206 in mammary cancer models

Ronald A. Lubet, Vernon E. Steele, M. M. Juliana, Ann Bode, Fariba Moeinpour, Clinton J. Grubbs
Pages: 718-718
Published online on: 17 October 2018

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Correction Open Access

[Corrigendum] AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis

Yun Jung Choi, Ji Hye Kim, Jin Kyung Rho, Joong Sun Kim, Chang-Min Choi, Woo Sung Kim, Jaekyoung Son, Jae Cheol Lee
Pages: 719-719
Published online on: 29 October 2018

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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