|
1
|
Bischoff JR, Anderson L, Zhu Y, Mossie K,
Ng L, Souza B, Schryver B, Flanagan P, Clairvoyant F, Ginther C, et
al: A homologue of Drosophila aurora kinase is oncogenic and
amplified in human colorectal cancers. EMBO J. 17:3052–3065. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wang X, Zhou YX, Qiao W, Tominaga Y, Ouchi
M, Ouchi T and Deng CX: Overexpression of aurora kinase A in mouse
mammary epithelium induces genetic instability preceding mammary
tumor formation. Oncogene. 25:7148–7158. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW,
Sahin A, Brinkley BR and Sen S: Tumour amplified kinase STK15/BTAK
induces centrosome amplification, aneuploidy and transformation.
Nat Genet. 20:189–193. 1998. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Fu J, Bian M, Jiang Q and Zhang C: Roles
of Aurora kinases in mitosis and tumorigenesis. Mol Cancer Res.
5:1–10. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Katayama H, Brinkley WR and Sen S: The
Aurora kinases: Role in cell transformation and tumorigenesis.
Cancer Metastasis Rev. 22:451–464. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Chen JM, Chiu SC, Wei TY, Lin SY, Chong
CM, Wu CC, Huang JY, Yang ST, Ku CF, Hsia JY and Yu CT: The
involvement of nuclear factor-κappaB in the nuclear targeting and
cyclin E1 upregulating activities of hepatoma upregulated protein.
Cell Signal. 27:26–36. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yu CT, Hsu JM, Lee YC, Tsou AP, Chou CK
and Huang CY: Phosphorylation and stabilization of HURP by
Aurora-A: Implication of HURP as a transforming target of Aurora-A.
Mol Cell Biol. 25:5789–5800. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kopnin BP: Targets of oncogenes and tumor
suppressors: Key for understanding basic mechanisms of
carcinogenesis. Biochemistry (Mosc). 65:2–27. 2000.PubMed/NCBI
|
|
9
|
Liu CW, Wang RH and Berndt N: Protein
phosphatase 1alpha activity prevents oncogenic transformation. Mol
Carcinog. 45:648–656. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
10
|
Berndt N, Dohadwala M and Liu CW:
Constitutively active protein phosphatase 1alpha causes
Rb-dependent G1 arrest in human cancer cells. Curr Biol. 7:375–386.
1997. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Liu CW, Wang RH, Dohadwala M, Schönthal
AH, Villa-Moruzzi E and Berndt N: Inhibitory phosphorylation of
PP1alpha catalytic subunit during the G(1)/S transition. J Biol
Chem. 274:29470–29475. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ayllón V, Martínez AC, García A, Cayla X
and Rebollo A: Protein phosphatase 1alpha is a Ras-activated Bad
phosphatase that regulates interleukin-2 deprivation-induced
apoptosis. EMBO J. 19:2237–2246. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Dessauge F, Cayla X, Albar JP, Fleischer
A, Ghadiri A, Duhamel M and Rebollo A: Identification of PP1alpha
as a caspase-9 regulator in IL-2 deprivation-induced apoptosis. J
Immunol. 177:2441–2451. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Eke I, Koch U, Hehlgans S, Sandfort V,
Stanchi F, Zips D, Baumann M, Shevchenko A, Pilarsky C, Haase M, et
al: PINCH1 regulates Akt1 activation and enhances radioresistance
by inhibiting PP1alpha. J Clin Invest. 120:2516–2527. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wang RH, Liu CW, Avramis VI and Berndt N:
Protein phosphatase 1alpha-mediated stimulation of apoptosis is
associated with dephosphorylation of the retinoblastoma protein.
Oncogene. 20:6111–6122. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Imai Y, Kakinoki Y, Takizawa N, Nakamura
K, Shima H and Kikuchi K: Up-regulation of nuclear PP1alpha and
PP1delta in hepatoma cells. Int J Oncol. 14:121–126.
1999.PubMed/NCBI
|
|
17
|
Nomoto K, Shibata N, Imai Y, Kitamura K,
Nakamura K, Mizuno Y and Kikuchi K: Activation of protein
phosphatase 1alpha promoter in ascites hepatoma cells. Int J Oncol.
13:331–334. 1998.PubMed/NCBI
|
|
18
|
Takizawa N, Mizuno Y, Saadat M and Kikuchi
K: Selective increases in isoform PP1 alpha of type-1 protein
phosphatase in ascites hepatoma cells. Jpn J Cancer Res.
85:274–278. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Prowatke I, Devens F, Benner A, Gröne EF,
Mertens D, Gröne HJ, Lichter P and Joos S: Expression analysis of
imbalanced genes in prostate carcinoma using tissue microarrays. Br
J Cancer. 96:82–88. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Troutaud D, Petit B, Bellanger C, Marin B,
Gourin-Chaury MP, Petit D, Olivrie A, Feuillard J, Jauberteau MO
and Bordessoule D: Prognostic significance of BAD and AIF apoptotic
pathways in diffuse large B-cell lymphoma. Clin Lymphoma Myeloma
Leuk. 10:118–124. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hsu LC, Huang X, Seasholtz S, Potter DM
and Gollin SM: Gene amplification and overexpression of protein
phosphatase 1alpha in oral squamous cell carcinoma cell lines.
Oncogene. 25:5517–5526. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Mei Y, Liu YB, Cao S, Tian ZW and Zhou HH:
RIF1 promotes tumor growth and cancer stem cell-like traits in
NSCLC by protein phosphatase 1-mediated activation of Wnt/β-catenin
signaling. Cell Death Dis. 9:9422018. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chen PC, Li C, Wang D, Luo ZW, Fu SJ, Li
X, Li ZL, Chen XW, Li L, Huang ZX, et al: PP-1α and PP-1γ display
antagonism and differential roles in tumorigenicity of lung cancer
cells. Curr Mol Med. 13:220–227. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Verdugo-Sivianes EM, Navas L,
Molina-Pinelo S, Ferrer I, Quintanal-Villalonga A, Peinado J,
Garcia-Heredia JM, Felipe-Abrio B, Muñoz-Galvan S, Marin JJ, et al:
Coordinated downregulation of Spinophilin and the catalytic
subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in
lung cancer. Oncotarget. 8:105196–105210. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kim W, Youn H, Kang C and Youn B:
Inflammation-induced radioresistance is mediated by ROS-dependent
inactivation of protein phosphatase 1 in non-small cell lung cancer
cells. Apoptosis. 20:1242–1252. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Liu F, Yang X, Geng M and Huang M:
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer
therapy. Acta Pharm Sin B. 8:552–562. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Mayer IA and Arteaga CL: The PI3K/AKT
pathway as a target for cancer treatment. Annu Rev Med. 67:11–28.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Selim KA, Abdelrasoul H, Aboelmagd M and
Tawila AM: The role of the MAPK signaling, topoisomerase and
dietary bioactives in controlling cancer incidence. Diseases.
5(pii): E132017. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Carnero A and Paramio JM: The
PTEN/PI3K/AKT Pathway in vivo, cancer mouse models. Front Oncol.
4:2522014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Garcia-Echeverria C and Sellers WR: Drug
discovery approaches targeting the PI3K/Akt pathway in cancer.
Oncogene. 27:5511–5526. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Robertson BW, Bonsal L and Chellaiah MA:
Regulation of Erk1/2 activation by osteopontin in PC3 human
prostate cancer cells. Mol Cancer. 9:2602010. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Shi ZZ, Shang L, Jiang YY, Shi F, Xu X,
Wang MR and Hao JJ: Identification of genomic biomarkers associated
with the clinicopathological parameters and prognosis of esophageal
squamous cell carcinoma. Cancer Biomark. 15:755–761. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Chunli W, Jiajie H, Lifei W, Beiqing P,
Xin X, Yan C, Mingrong W and Xuemei J: IGHMBP2 overexpression
promotes cell migration and invasion in esophageal squamous
carcinoma. Yi Chuan. 37:360–366. 2015.(In Chinese). PubMed/NCBI
|
|
34
|
Sawada G, Niida A, Hirata H, Komatsu H,
Uchi R, Shimamura T, Takahashi Y, Kurashige J, Matsumura T, Ueo H,
et al: An integrative analysis to identify driver genes in
esophageal squamous cell carcinoma. PLoS One. 10:e01398082015.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Onkes W, Fredrik R, Micci F, Schönbeck BJ,
Martin-Subero JI, Ullmann R, Hilpert F, Bräutigam K, Janssen O,
Maass N, et al: Breakpoint characterization of the
der(19)t(11;19)(q13;p13) in the ovarian cancer cell line SKOV-3.
Genes Chromosomes Cancer. 52:512–522. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wang L, Wenners A, Hilpert F, Fredrik R,
Micci F, Onkes W, Caliebe A, Maass N, Weimer J and Arnold N:
Frequent translocations of 11q13.2 and 19p13.2 in ovarian cancer.
Genes Chromosomes Cancer. 53:447–453. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Sárová I, Březinová J, Zemanová Z,
Gančarčíková M, Vydra J, Cermák J and Michalová K: Rearrangement of
11q13.2 region in two patients with acute myeloid leukemia. Leuk
Res. 37:4792013. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Hooker S, Hernandez W, Chen H, Robbins C,
Torres JB, Ahaghotu C, Carpten J and Kittles RA: Replication of
prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in
African Americans. Prostate. 70:270–275. 2010.PubMed/NCBI
|
|
39
|
Waters KM, Le Marchand L, Kolonel LN,
Monroe KR, Stram DO, Henderson BE and Haiman CA: Generalizability
of associations from prostate cancer genome-wide association
studies in multiple populations. Cancer Epidemiol Biomarkers Prev.
18:1285–1289. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Bocanegra M, Bergamaschi A, Kim YH, Miller
MA, Rajput AB, Kao J, Langerød A, Han W, Noh DY, Jeffrey SS, et al:
Focal amplification and oncogene dependency of GAB2 in breast
cancer. Oncogene. 29:774–779. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Chunder N, Mandal S, Roy A, Roychoudhury S
and Panda CK: Analysis of different deleted regions in chromosome
11 and their interrelations in early- and late-onset breast tumors:
Association with cyclin D1 amplification and survival. Diagn Mol
Pathol. 13:172–182. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Weilandt M, Koch A, Rieder H, Deenen R,
Schwender H, Niegisch G and Schulz WA: Target genes of recurrent
chromosomal amplification and deletion in urothelial carcinoma.
Cancer Genomics Proteomics. 11:141–153. 2014.PubMed/NCBI
|
|
43
|
Sia D, Hoshida Y, Villanueva A, Roayaie S,
Ferrer J, Tabak B, Peix J, Sole M, Tovar V, Alsinet C, et al:
Integrative molecular analysis of intrahepatic cholangiocarcinoma
reveals 2 classes that have different outcomes. Gastroenterology.
144:829–840. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Chen CF, Hsu EC, Lin KT, Tu PH, Chang HW,
Lin CH, Chen YJ, Gu DL, Lin CH, Wu JY, et al: Overlapping
high-resolution copy number alterations in cancer genomes
identified putative cancer genes in hepatocellular carcinoma.
Hepatology. 52:1690–1701. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Gruel N, Lucchesi C, Raynal V, Rodrigues
MJ, Pierron G, Goudefroye R, Cottu P, Reyal F, Sastre-Garau X,
Fourquet A, et al: Lobular invasive carcinoma of the breast is a
molecular entity distinct from luminal invasive ductal carcinoma.
Eur J Cancer. 46:2399–2407. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Chang CC, Zhou X, Taylor JJ, Huang WT, Ren
X, Monzon F, Feng Y, Rao PH, Lu XY, Fabio F, et al: Genomic
profiling of plasmablastic lymphoma using array comparative genomic
hybridization (aCGH): Revealing significant overlapping genomic
lesions with diffuse large B-cell lymphoma. J Hematol Oncol.
2:472009. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Sarova I, Brezinova J, Zemanova Z,
Bystricka D, Krejcik Z, Soukup P, Vydra J, Cermak J, Jonasova A and
Michalova K: Characterization of chromosome 11 breakpoints and the
areas of deletion and amplification in patients with newly
diagnosed acute myeloid leukemia. Genes Chromosomes Cancer.
52:619–635. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Serio G, Gentile M, Pennella A, Marzullo
A, Buonadonna AL, Nazzaro P, Testini M, Musti M and Scattone A:
Characterization of a complex chromosome aberration in two cases of
peritoneal mesothelioma arising primarily in the hernial sac.
Pathol Int. 59:415–421. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Senda K, Goi T, Hirono Y, Katayama K and
Yamaguchi A: Analysis of RIN1 gene expression in colorectal cancer.
Oncol Rep. 17:1171–1175. 2007.PubMed/NCBI
|
|
50
|
Boukamp P, Popp S, Bleuel K, Tomakidi E,
Bürkle A and Fusenig NE: Tumorigenic conversion of immortal human
skin keratinocytes (HaCaT) by elevated temperature. Oncogene.
18:5638–5645. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Llorian M, Beullens M, Andrés I, Ortiz JM
and Bollen M: SIPP1, a novel pre-mRNA splicing factor and
interactor of protein phosphatase-1. Biochem J. 378:P229–P238.
2004. View Article : Google Scholar
|
|
52
|
Chen M, Wan L, Zhang J, Zhang J, Mendez L,
Clohessy JG, Berry K, Victor J, Yin Q, Zhu Y, et al: Deregulated
PP1α phosphatase activity towards MAPK activation is antagonized by
a tumor suppressive failsafe mechanism. Nat Commun. 9:1592018.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Chen PH, Tsao YP, Wang CC and Chen SL:
Nuclear receptor interaction protein, a coactivator of androgen
receptors (AR), is regulated by AR and Sp1 to feed forward and
activate its own gene expression through AR protein stability.
Nucleic Acids Res. 36:51–66. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Yang Y, Tse AK, Li P, Ma Q, Xiang S,
Nicosia SV, Seto E, Zhang X and Bai W: Inhibition of androgen
receptor activity by Histone deacetylase 4 through receptor
SUMOylation. Oncogene. 30:2207–2218. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Wei TY, Hsia JY, Chiu SC, Su LJ, Juan CC,
Lee YC, Chen JM, Chou HY, Huang JY, Huang HM and Yu CT: Methylosome
protein 50 promotes androgen- and estrogen-independent
tumorigenesis. Cell Signal. 26:2940–2950. 2014. View Article : Google Scholar : PubMed/NCBI
|
