|
1
|
Ducreux M, Seufferlein T, Van Laethem JL,
Laurent-Puig P, Smolenschi C, Malka D, Boige V, Hollebecque A and
Conroy T: Systemic treatment of pancreatic cancer revisited. Semin
Oncol. 46:28–38. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ilic M and Ilic I: Epidemiology of
pancreatic cancer. World J Gastroenterol. 22:9694–9705. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
McGuigan A, Kelly P, Turkington RC, Jones
C, Coleman HG and McCain RS: Pancreatic cancer: A review of
clinical diagnosis, epidemiology, treatment and outcomes. World J
Gastroenterol. 24:4846–4861. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Wang J, Wang B, Ren H and Chen W: miR-9-5p
inhibits pancreatic cancer cell proliferation, invasion and
glutamine metabolism by targeting GOT1. Biochem Biophys Res Commun.
509:241–248. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Liang J, Liu Y, Zhang L, Tan J, Li E and
Li F: Overexpression of microRNA-519d-3p suppressed the growth of
pancreatic cancer cells by inhibiting ribosomal protein
S15A-mediated Wnt/beta-catenin signaling. Chem Biol Interact.
304:1–9. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lin QJ, Yang F, Jin C and Fu DL: Current
status and progress of pancreatic cancer in China. World J
Gastroenterol. 21:7988–8003. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Goess R and Friess H: A look at the
progress of treating pancreatic cancer over the past 20 years.
Expert Rev Anticancer Ther. 18:295–304. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Yu Z, Wang R, Chen F, Wang J and Huang X:
Five novel oncogenic signatures could be utilized as AFP-related
diagnostic biomarkers for hepatocellular carcinoma based on
next-generation sequencing. Dig Dis Sci. 63:945–957. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen J, Wu F, Shi Y, Yang D, Xu M, Lai Y
and Liu Y: Identification of key candidate genes involved in
melanoma metastasis. Mol Med Rep. 20:903–914. 2019.PubMed/NCBI
|
|
10
|
Kim WT, Seo SP, Byun YJ, Kang HW, Kim YJ,
Lee SC, Jeong P, Song HJ, Choe SY, Kim DJ, et al: The anticancer
effects of garlic extracts on bladder cancer compared to cisplatin:
A common mechanism of action via centromere protein M. Am J Chin
Med. 46:689–705. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Perpelescu M and Fukagawa T: The ABCs of
CENPs. Chromosoma. 120:425–446. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Chen Q, Hu J, Deng J, Fu B and Guo J:
Bioinformatics analysis identified key molecular changes in bladder
cancer development and recurrence. Biomed Res Int.
2019:39179822019. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Foltz DR, Jansen LE, Black BE, Bailey AO,
Yates JR III and Cleveland DW: The human CENP-A centromeric
nucleosome-sassociated complex. Nat Cell Biol. 8:458–469. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Izuta H, Ikeno M, Suzuki N, Tomonaga T,
Nozaki N, Obuse C, Kisu Y, Goshima N, Nomura F, Nomura N and Yoda
K: Comprehensive analysis of the ICEN (Interphase Centromere
Complex) components enriched in the CENP-A chromatin of human
cells. Genes Cells. 11:673–684. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Grützmann R, Pilarsky C, Ammerpohl O,
Lüttges J, Böhme A, Sipos B, Foerder M, Alldinger I, Jahnke B,
Schackert HK, et al: Gene expression profiling of microdissected
pancreatic ductal carcinomas using high-density DNA microarrays.
Neoplasia. 6:611–622. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Pei H, Li L, Fridley BL, Jenkins GD,
Kalari KR, Lingle W, Petersen G, Lou Z and Wang L: FKBP51 affects
cancer cell response to chemotherapy by negatively regulating Akt.
Cancer Cell. 16:259–266. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Daniel R, Rhodes JY and Arul M:
Chinnaiyan, ONCOMINE-A cancer microarray database and integrated
data-mining platform. Neoplasia. 6:1–6. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Tang Z, Li C, Kang B, Gao G, Li C and
Zhang Z: GEPIA: A web server for cancer and normal gene expression
profiling and interactive analyses. Nucleic Acids Res. 45:W98–W102.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Malumbres M: Cyclin-dependent kinases.
Genome Biol. 15(122)2014.PubMed/NCBI
|
|
21
|
Park EY, Woo Y, Kim SJ, Kim DH, Lee EK, De
U, Kim KS, Lee J, Jung JH, Ha KT, et al: Anticancer effects of a
new SIRT inhibitor, MHY2256, against Human Breast Cancer MCF-7
cells via regulation of MDM2-p53 binding. Int J Biolo Sci.
12:1555–1567. 2016. View Article : Google Scholar
|
|
22
|
Bosetti C, Bertuccio P, Negri E, La
Vecchia C, Zeegers MP and Boffetta P: Pancreatic cancer: Overview
of descriptive epidemiology. Mol Carcinog. 51:3–13. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chu QD, Sun G, Pope M, Luraguiz N, Curiel
DT, Kim R, Li BD and Mathis JM: Virotherapy using a novel chimeric
oncolytic adenovirus prolongs survival in a human pancreatic cancer
xenograft model. Surgery. 152:441–448. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Yamamoto Y, Hiraoka N, Goto N, Rin Y,
Miura K, Narumi K, Uchida H, Tagawa M and Aoki K: A targeting
ligand enhances infectivity and cytotoxicity of an oncolytic
adenovirus in human pancreatic cancer tissues. J Control Release.
192:284–293. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Bierie B, Edwin M, Melenhorst JJ and
Hennighausen L: The proliferation associated nuclear element
(PANE1) is conserved between mammals and fish and preferentially
expressed in activated lymphoid cells. Gene Expr Patterns.
4:389–395. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Renou JP, Bierie B, Miyoshi K, Cui Y,
Djiane J, Reichenstein M, Shani M and Hennighausen L:
Identification of genes differentially expressed in mouse mammary
epithelium transformed by an activated beta-catenin. Oncogene.
22:4594–4610. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Okada M, Cheeseman IM, Hori T, Okawa K,
McLeod IX, Yates JR III, Desai A and Fukagawa T: The CENP-H-I
complex is required for the efficient incorporation of newly
synthesized CENP-A into centromeres. Nat Cell Biol. 8:446–457.
2006. View
Article : Google Scholar : PubMed/NCBI
|
|
28
|
Xiao Y, Najeeb RM, Ma D, Yang K, Zhong Q
and Liu Q: Upregulation of CENPM promotes hepatocarcinogenesis
through mutiple mechanisms. J Exp Clin Cancer Res. 38:4582019.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Basilico F, Maffini S, Weir JR, Prumbaum
D, Rojas AM, Zimniak T, De Antoni A, Jeganathan S, Voss B, van
Gerwen S, et al: The pseudo GTPase CENP-M drives human kinetochore
assembly. Elife. 3:e029782014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Gopal Krishnan PD, Golden E, Woodward EA,
Pavlos NJ and Blancafort P: Rab GTPases: Emerging oncogenes and
tumor suppressive regulators for the editing of survival pathways
in cancer. Cancers (Basel). 12:2592020. View Article : Google Scholar
|
|
31
|
Thomas JD, Zhang YJ, Wei YH, Cho JH,
Morris LE, Wang HY and Zheng XF: Rab1A is an MTORC1 activator and a
colorectal oncogene. Cancer Cell. 26:754–769. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Magnuson B, Ekim B and Fingar DC:
Regulation and function of ribosomal protein S6 kinase (S6K) within
mTOR signalling networks. Biochem J. 441:1–21. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Tavares MR, Pavan IC, Amaral CL,
Meneguello L, Luchessi AD and Simabuco FM: The S6K protein family
in health and disease. Life Sci. 131:1–10. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Hall MN: mTOR-what does it do? Transplant
Proc. 40 (Suppl 10):S5–S8. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Holz MK and Blenis J: Identification of S6
kinase 1 as a novel mammalian target of rapamycin
(mTOR)-phosphorylating kinase. J Biol Chem. 280:26089–26093. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Pende M, Um SH, Mieulet V, Sticker M, Goss
VL, Mestan J, Mueller M, Fumagalli S, Kozma SC and Thomas G:
S6K1(−/-)/S6K2(−/-) mice exhibit perinatal lethality and
rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation
and reveal a mitogen-activated protein kinase-dependent S6 kinase
pathway. Mol Cell Biol. 24:3112–3124. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Skinner HD, Zhong XS, Gao N, Shi X and
Jiang BH: Arsenite induces p70S6K1 activation and HIF-1alpha
expression in prostate cancer cells. Mol Cell Biochem. 255:19–23.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Athamneh K, Alneyadi A, Alsamri H,
Alrashedi A, Palakott A, El-Tarabily KA, Eid AH, Al Dhaheri Y and
Iratni R: Origanum majorana essential Oil triggers p38
MAPK-mediated protective autophagy, apoptosis, and
caspase-dependent cleavage of P70S6K in colorectal cancer cells.
Biomolecules. 10:4122020. View Article : Google Scholar
|
|
39
|
Liu J, Ren Y, Hou Y, Zhang C, Wang B, Li
X, Sun R and Liu J: Dihydroartemisinin induces endothelial cell
autophagy through suppression of the Akt/mTOR pathway. J Cancer.
10:6057–6064. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Martina JA, Chen Y, Gucek M and
Puertollano R: MTORC1 functions as a transcriptional regulator of
autophagy by preventing nuclear transport of TFEB. Autophagy.
8:913–914. 2012. View Article : Google Scholar
|
|
41
|
Holz MK, Ballif BA, Gygi SP and Blenis J:
mTOR and S6K1 mediate assembly of the translation preinitiation
complex through dynamic protein interchange and ordered
phosphorylation events. Cell. 123:569–580. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Ashrafizadeh M, Rafiei H, Mohammadinejad
R, Afshar EG, Farkhondeh T and Samarghandian S: Potential
therapeutic effects of curcumin mediated by JAK/STAT signaling
pathway: A review. Phytother Res. Mar 10–2020.(Epub ahead of
print). View Article : Google Scholar
|
|
43
|
Xing J, Bhuria V, Bui KC, Nguyen MLT, Hu
Z, Hsieh CJ, Wittstein K, Stadler M, Wilkens L, Li J, et al:
Haprolid inhibits tumor growth of hepatocellular carcinoma through
Rb/E2F and Akt/mTOR inhibition. Cancers (Basel). 12:6152020.
View Article : Google Scholar
|
|
44
|
Ichimaru Y, Sano M, Kajiwara I, Tobe T,
Yoshioka H, Hayashi K, Ijichi H and Miyairi S: Indirubin 3′-oxime
inhibits migration, invasion, and metastasis InVivo in mice bearing
spontaneously occurring pancreatic cancer via blocking the RAF/ERK,
AKT, and SAPK/JNK Pathways. Transl Oncol. 12:1574–1582. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Han F, Xu Q, Zhao J, Xiong P and Liu J:
ERO1L promotes pancreatic cancer cell progression through
activating the Wnt/catenin pathway. J Cell Biochem. 119:8996–9005.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Yang K, Li Y, Lian G, Lin H, Shang C, Zeng
L, Chen S, Li J, Huang C, Huang K and Chen Y: KRAS promotes tumor
metastasis and chemoresistance by repressing RKIP via the MAPK-ERK
pathway in pancreatic cancer. Int J Cancer. 142:2323–2334. 2018.
View Article : Google Scholar : PubMed/NCBI
|
