1
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar
|
2
|
Chu D and Lu J: Novel therapies in breast
cancer: What is new from ASCO 2008. J Hematol Oncol. 1:162008.
View Article : Google Scholar
|
3
|
Chinese Anti-Cancer Association, Committee
of Breast Cancer Society. Chinese expert consensus on the clinical
diagnosis and treatment of advanced breast carcinoma(2018).
Zhonghua Zhong Liu Za Zhi. 40((9)): 703–713. 2018.(In Chinese).
|
4
|
Luo M, Clouthier SG, Deol Y, Liu S,
Nagrath S, Azizi E and Wicha MS: Breast cancer stem cells: Current
advances and clinical implications. Methods Mol Biol. 1293:1–49.
2015. View Article : Google Scholar
|
5
|
Yang F, Xu J, Tang L and Guan X: Breast
cancer stem cell: The roles and therapeutic implications. Cell Mol
Life Sci. 74:951–966. 2017. View Article : Google Scholar
|
6
|
Bunting KD: ABC transporters as phenotypic
markers and functional regulators of stem cells. Stem Cells.
20:11–20. 2002. View Article : Google Scholar
|
7
|
Liu Y, Burness ML, Martin-Trevino R, Guy
J, Bai S, Harouaka R, Brooks MD, Shang L, Fox A, Luther TK, et al:
RAD51 mediates resistance of cancer stem cells to PARP inhibition
in triple-negative breast cancer. Clin Cancer Res. 23:514–522.
2017. View Article : Google Scholar
|
8
|
Butti R, Gunasekaran VP, Kumar TVS,
Banerjee P and Kundu GC: Breast cancer stem cells: Biology and
therapeutic implications. Int J Biochem Cell Biol. 107:38–52. 2019.
View Article : Google Scholar
|
9
|
Gupta P, Wright SE, Kim SH and Srivastava
SK: Phenethyl isothiocyanate: A comprehensive review of anti-cancer
mechanisms. Biochim Biophys Acta. 1846:405–424. 2014.
|
10
|
Trachootham D, Zhang H, Zhang W, Feng L,
Du M, Zhou Y, Chen Z, Pelicano H, Plunkett W, Wierda WG, et al:
Effective elimination of fludarabine-resistant CLL cells by PEITC
through a redox-mediated mechanism. Blood. 112:1912–1922. 2008.
View Article : Google Scholar
|
11
|
Trachootham D, Zhou Y, Zhang H, Demizu Y,
Chen Z, Pelicano H, Chiao PJ, Achanta G, Arlinghaus RB, Liu J, et
al: Selective killing of oncogenically transformed cells through a
ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer
Cell. 10:241–252. 2006. View Article : Google Scholar
|
12
|
Zhang T, Shao Y, Chu TY, Huang HS, Liou
YL, Li Q and Zhou H: MiR-135a and MRP1 play pivotal roles in the
selective lethality of phenethyl isothiocyanate to malignant glioma
cells. Am J Cancer Res. 6:957–972. 2016.
|
13
|
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q,
Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, et al: Phenethyl
isothiocyanate inhibits colorectal cancer stem cells by suppressing
Wnt/β-catenin pathway. Phytother Res. 32:2447–2455. 2018.
View Article : Google Scholar
|
14
|
Liou YL, Zhang TL, Yan T, Yeh CT, Kang YN,
Cao L, Wu N, Chang CF, Wang HJ, Yen C, et al: Combined clinical and
genetic testing algorithm for cervical cancer diagnosis. Clin
Epigenetics. 8:662016. View Article : Google Scholar
|
15
|
Pasculli B, Barbano R and Parrella P:
Epigenetics of breast cancer: Biology and clinical implication in
the era of precision medicine. Semin Cancer Biol. 51:22–35. 2018.
View Article : Google Scholar
|
16
|
Liu T, Wu X, Chen T, Luo Z and Hu X:
Downregulation of DNMT3A by miR-708-5p inhibits lung cancer stem
cell-like phenotypes through repressing Wnt/β-catenin signaling.
Clin Cancer Res. 24:1748–1760. 2018. View Article : Google Scholar
|
17
|
Yu F, Jiao Y, Zhu Y, Wang Y, Zhu J, Cui X,
Liu Y, He Y, Park EY, Zhang H, et al: MicroRNA 34c gene
down-regulation via DNA methylation promotes self-renewal and
epithelial-mesenchymal transition in breast tumor-initiating cells.
J Biol Chem. 287:465–473. 2012. View Article : Google Scholar
|
18
|
Sun L, Mathews LA, Cabarcas SM, Zhang X,
Yang A, Zhang Y, Young MR, Klarmann KD, Keller JR and Farrar WL:
Epigenetic regulation of SOX9 by the NF-κB signaling pathway in
pancreatic cancer stem cells. Stem Cells. 31:1454–1466. 2013.
View Article : Google Scholar
|
19
|
Boyanapalli SS, Li W, Fuentes F, Guo Y,
Ramirez CN, Gonzalez XP, Pung D and Kong AN: Epigenetic
reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and
promotion of apoptosis in LNCaP cells. Pharmacol Res. 114:175–184.
2016. View Article : Google Scholar
|
20
|
Gupta R, Bhatt LK and Momin M: Potent
antitumor activity of Laccaic acid and Phenethyl isothiocyanate
combination in colorectal cancer via dual inhibition of DNA
methyltransferase-1 and Histone deacetylase-1. Toxicol Appl
Pharmacol. 377:1146312019. View Article : Google Scholar
|
21
|
Berx G and van Roy F: Involvement of
members of the cadherin superfamily in cancer. Cold Spring Harb
Perspect Biol. 1:a0031292009. View Article : Google Scholar
|
22
|
Shinozaki M, Hoon DS, Giuliano AE, Hansen
NM, Wang HJ, Turner R and Taback B: Distinct hypermethylation
profile of primary breast cancer is associated with sentinel lymph
node metastasis. Clin Cancer Res. 11:2156–2162. 2005. View Article : Google Scholar
|
23
|
Ma F, Li W, Liu C, Li W, Yu H, Lei B, Ren
Y, Li Z, Pang D and Qian C: MiR-23a promotes TGF-β1-induced EMT and
tumor metastasis in breast cancer cells by directly targeting CDH1
and activating Wnt/β-catenin signaling. Oncotarget. 8:69538–69550.
2017. View Article : Google Scholar
|
24
|
Huang R, Ding P and Yang F:
Clinicopathological significance and potential drug target of CDH1
in breast cancer: A meta-analysis and literature review. Drug Des
Devel Ther. 9:5277–5285. 2015.
|
25
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
26
|
Park JE, Sun Y, Lim SK, Tam JP, Dekker M,
Chen H and Sze SK: Dietary phytochemical PEITC restricts tumor
development via modulation of epigenetic writers and erasers. Sci
Rep. 7:405692017. View Article : Google Scholar
|
27
|
Zheng A, Song X, Zhang L, Zhao L, Mao X,
Wei M and Jin F: Long non-coding RNA LUCAT1/miR-5582-3p/TCF7L2 axis
regulates breast cancer stemness via Wnt/β-catenin pathway. J Exp
Clin Cancer Res. 38:3052019. View Article : Google Scholar
|
28
|
Lawson DA, Bhakta NR, Kessenbrock K,
Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY,
et al: Single-cell analysis reveals a stem-cell program in human
metastatic breast cancer cells. Nature. 526:131–135. 2015.
View Article : Google Scholar
|
29
|
Tsang JY, Huang YH, Luo MH, Ni YB, Chan
SK, Lui PC, Yu AM, Tan PH and Tse GM: Cancer stem cell markers are
associated with adverse biomarker profiles and molecular subtypes
of breast cancer. Breast Cancer Res Treat. 136:407–417. 2012.
View Article : Google Scholar
|
30
|
Almozyan S, Colak D, Mansour F, Alaiya A,
Al-Harazi O, Qattan A, Al-Mohanna F, Al-Alwan M and Ghebeh H: PD-L1
promotes OCT4 and Nanog expression in breast cancer stem cells by
sustaining PI3K/AKT pathway activation. Int J Cancer.
141:1402–1412. 2017. View Article : Google Scholar
|
31
|
Das S, Mukherjee P, Chatterjee R, Jamal Z
and Chatterji U: Enhancing chemosensitivity of breast cancer stem
cells by downregulating SOX2 and ABCG2 using
wedelolactone-encapsulated nanoparticles. Mol Cancer Ther.
18:680–692. 2019. View Article : Google Scholar
|
32
|
Matsumura T, Makino R and Mitamura K:
Frequent down-regulation of E-cadherin by genetic and epigenetic
changes in the malignant progression of hepatocellular carcinomas.
Clin Cancer Res. 7:594–599. 2001.
|
33
|
Gelato KA, Shaikhibrahim Z, Ocker M and
Haendler B: Targeting epigenetic regulators for cancer therapy:
Modulation of bromodomain proteins, methyltransferases,
demethylases, and microRNAs. Expert Opin Ther Targets. 20:783–799.
2016. View Article : Google Scholar
|
34
|
Lecarpentier Y, Schussler O, Hébert JL and
Vallée A: Multiple targets of the canonical WNT/β-catenin signaling
in cancers. Front Oncol. 9:12482019. View Article : Google Scholar
|
35
|
Wang D, Upadhyaya B, Liu Y, Knudsen D and
Dey M: Phenethyl isothiocyanate upregulates death receptors 4 and 5
and inhibits proliferation in human cancer stem-like cells. BMC
Cancer. 14:5912014. View Article : Google Scholar
|
36
|
Koschorke A, Faraci S, Giani D, Chiodoni
C, Iorio E, Canese R, Colombo MP, Lamolinara A, Iezzi M, Ladomery
M, et al: Phenethyl isothiocyanate hampers growth and progression
of HER2-positive breast and ovarian carcinoma by targeting their
stem cell compartment. Cell Oncol (Dordr). 42:815–828. 2019.
View Article : Google Scholar
|
37
|
Sarkar R, Mukherjee S, Biswas J and Roy M:
Phenethyl isothiocyanate, by virtue of its antioxidant activity,
inhibits invasiveness and metastatic potential of breast cancer
cells: HIF-1α as a putative target. Free Radic Res. 50:84–100.
2016. View Article : Google Scholar
|
38
|
Gupta P, Adkins C, Lockman P and
Srivastava SK: Metastasis of breast tumor cells to brain is
suppressed by phenethyl isothiocyanate in a novel in vivo
metastasis model. PLoS One. 8:e672782013. View Article : Google Scholar
|
39
|
Henkin RI: Clinical and therapeutic
implications of cancer stem cells. N Engl J Med. 381:e192019.
View Article : Google Scholar
|
40
|
Pratheeshkumar P, Sreekala C, Zhang Z,
Budhraja A, Ding S, Son YO, Wang X, Hitron A, Hyun-Jung K, Wang L,
et al: Cancer prevention with promising natural products:
Mechanisms of action and molecular targets. Anticancer Agents Med
Chem. 12:1159–1184. 2012. View Article : Google Scholar
|
41
|
Palermo R, Ghirga F, Piccioni MG, Bernardi
F, Zhdanovskaya N, Infante P and Mori M: Natural products inspired
modulators of cancer stem cells-specific signaling pathways Notch
and Hedgehog. Curr Pharm Des. 24:4251–4269. 2018. View Article : Google Scholar
|
42
|
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ,
Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, et al: Curcumin suppresses
lung cancer stem cells via inhibiting Wnt/β-catenin and aonic
Hedgehog pathways. Phytother Res. 31:680–688. 2017. View Article : Google Scholar
|
43
|
Huang YT, Lin YW, Chiu HM and Chiang BH:
Curcumin induces apoptosis of colorectal cancer stem cells by
coupling with CD44 marker. J Agric Food Chem. 64:2247–2253. 2016.
View Article : Google Scholar
|
44
|
Dandawate PR, Subramaniam D, Jensen RA and
Anant S: Targeting cancer stem cells and signaling pathways by
phytochemicals: Novel approach for breast cancer therapy. Semin
Cancer Biol. 40-41:192–208. 2016. View Article : Google Scholar
|
45
|
Chen L, Chan LS, Lung HL, Yip TTC, Ngan
RKC, Wong JWC, Lo KW, Ng WT, Lee AWM, Tsao GSW, et al: Crucifera
sulforaphane (SFN) inhibits the growth of nasopharyngeal carcinoma
through DNA methyltransferase 1 (DNMT1)/Wnt inhibitory factor 1
(WIF1) axis. Phytomedicine. 63:1530582019. View Article : Google Scholar
|
46
|
Ju HQ, Lu YX, Chen DL, Tian T, Mo HY, Wei
XL, Liao JW, Wang F, Zeng ZL, Pelicano H, et al: Redox regulation
of stem-like cells though the CD44v-xCT axis in colorectal cancer:
mechanisms and therapeutic implications. Theranostics. 6:1160–1175.
2016. View Article : Google Scholar
|
47
|
Upadhyaya B, Liu Y and Dey M: Phenethyl
isothiocyanate exposure promotes oxidative stress and suppresses
Sp1 transcription Factor in Cancer Stem Cells. Int J Mol Sci.
20:202019. View Article : Google Scholar
|
48
|
Feinberg AP, Koldobskiy MA and Göndör A:
Epigenetic modulators, modifiers and mediators in cancer aetiology
and progression. Nat Rev Genet. 17:284–299. 2016. View Article : Google Scholar
|
49
|
Pradhan N, Parbin S, Kar S, Das L, Kirtana
R, Suma Seshadri G, Sengupta D, Deb M, Kausar C and Patra SK:
Epigenetic silencing of genes enhanced by collective role of
reactive oxygen species and MAPK signaling downstream ERK/Snail
axis: Ectopic application of hydrogen peroxide repress CDH1 gene by
enhanced DNA methyltransferase activity in human breast cancer.
Biochim Biophys Acta Mol Basis Dis. 1865:1651–1665. 2019.
View Article : Google Scholar
|
50
|
Khan MA, Hussain A, Sundaram MK, Alalami
U, Gunasekera D, Ramesh L, Hamza A and Quraishi U:
(−)-Epigallocatechin-3-gallate reverses the expression of various
tumor-suppressor genes by inhibiting DNA methyltransferases and
histone deacetylases in human cervical cancer cells. Oncol Rep.
33:1976–1984. 2015. View Article : Google Scholar
|
51
|
Huang W, Zhao C, Zhong H, Zhang S, Xia Y
and Cai Z: Bisphenol S induced epigenetic and transcriptional
changes in human breast cancer cell line MCF-7. Environ Pollut.
246:697–703. 2019. View Article : Google Scholar
|
52
|
Lv YF, Dai H, Yan GN, Meng G, Zhang X and
Guo QN: Downregulation of tumor suppressing STF cDNA 3 promotes
epithelial-mesenchymal transition and tumor metastasis of
osteosarcoma by the Wnt/GSK-3β/β-catenin/Snail signaling pathway.
Cancer Lett. 373:164–173. 2016. View Article : Google Scholar
|