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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2021 Volume 45 Issue 1

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

PD‑L1/PD‑1 blockade in breast cancer: The immunotherapy era (Review)

Chia‑Jung Li, Li‑Te Lin, Ming‑Feng Hou, Pei‑Yi Chu
Pages: 5-12
Published online on: 03 November 2020

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Review Open Access

Safety and efficacy of anaplastic lymphoma kinase tyrosine kinase inhibitors in non‑small cell lung cancer (Review)

Li Wang, Wen Wang
Pages: 13-28
Published online on: 13 November 2020

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Review Open Access

Regulation of ferroptosis by non‑coding RNAs in the development and treatment of cancer (Review)

Yajun Luo, Qingmei Huang, Bin He, Yilei Liu, Siqi Huang, Jiangwei Xiao
Pages: 29-48
Published online on: 05 November 2020

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Review

Germline mutations and blood malignancy (Review)

Yuping Gong, Jili Deng, Xia Wu
Pages: 49-57
Published online on: 11 November 2020

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Review Open Access

Diagnostic and therapeutic role of microRNAs in oral cancer (Review)

Jing Wang, Najun Lv, Xinxin Lu, Rongtao Yuan, Zhenggang Chen, Jiangbo Yu
Pages: 58-64
Published online on: 13 November 2020

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Article Open Access

Methylation of the miR‑29b‑3p promoter contributes to angiogenesis, invasion, and migration in pancreatic cancer

Lihua Wang, Nv Mu, Nina Qu
Pages: 65-72
Published online on: 03 November 2020

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Article Open Access

Long non‑coding RNA ST8SIA6‑AS1 promotes the migration and invasion of hypoxia‑treated hepatocellular carcinoma cells through the miR‑338/MEPCE axis

Bin Zhang, Zhiyi Liu, Jin Liu, Kuan Cao, Wengang Shan, Quan Wen, Renhao Wang
Pages: 73-82
Published online on: 20 November 2020

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Article Open Access

Platelet‑derived growth factor‑BB mediates pancreatic cancer malignancy via regulation of the Hippo/Yes‑associated protein signaling pathway

Tao Li, Ting Guo, Houqin Liu, Hongtao Jiang, Yi Wang
Pages: 83-94
Published online on: 19 November 2020

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Article Open Access

Erb‑B2 Receptor Tyrosine Kinase 2 is negatively regulated by the p53‑responsive microRNA‑3184‑5p in cervical cancer cells

Hongli Liu, Yuzhi Li, Jing Zhang, Nan Wu, Fei Liu, Lihua Wang, Yuan Zhang, Jing Liu, Xuan Zhang, Suyang Guo, Hongtao Wang
Pages: 95-106
Published online on: 19 November 2020

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Article Open Access

Mesenchymal stem cells promote chemoresistance by activating autophagy in intrahepatic cholangiocarcinoma

Linhe Gan, Hao Shen, Xinduo Li, Zhipeng Han, Yingying Jing, Xue Yang, Mengchao Wu, Yong Xia
Pages: 107-118
Published online on: 06 November 2020

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Article Open Access

MicroRNA-134-3p inhibits ovarian cancer progression by targeting flap structure-specific endonuclease 1 in vitro

Mengshi Zhao, Hongjie Ji, Qiang Fu, Qian Cheng, Yu Zhang, Yu Yang
Pages: 119-128
Published online on: 10 November 2020

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Article Open Access

SOX12 contributes to the activation of the JAK2/STAT3 pathway and malignant transformation of esophageal squamous cell carcinoma

Chunguang Li, Maoling Zhu, Ji Zhu, Qijue Lu, Bowen Shi, Bin Sun, Hezhong Chen
Pages: 129-138
Published online on: 19 November 2020

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Article Open Access

Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma

Fengqi Jiang, Shuo Ren, Yaodong Chen, Ange Zhang, Yuekun Zhu, Zhenan Zhang, Zizhuo Li, Daxun Piao
Pages: 139-150
Published online on: 18 November 2020

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Article Open Access

S100A8 promotes chemoresistance via augmenting autophagy in B‑cell lymphoma cells

Li Zhang, Shixia Zhou, Tiejun Zhou, Kaifeng Yuan, Xiaoming Li, Junling Tang
Pages: 151-158
Published online on: 09 November 2020

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Article Open Access

A randomized phase III trial of personalized peptide vaccination for castration‑resistant prostate cancer progressing after docetaxel

Masanori Noguchi, Kiyohide Fujimoto, Gaku Arai, Hiroji Uemura, Katsuyoshi Hashine, Hiroaki Matsumoto, Satoshi Fukasawa, Yasuo Kohjimoto, Hideomi Nakatsu, Atsushi Takenaka, Masato Fujisawa, Hirotsugu Uemura, Seiji Naito, Shin Egawa, Hiroyuki Fujimoto, Shiro Hinotsu, Kyogo Itoh
Pages: 159-168
Published online on: 11 November 2020

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Article Open Access

circHIPK3 promotes proliferation and migration and invasion via regulation of miR‑637/HDAC4 signaling in osteosarcoma cells

Yu Wen, Bin Li, Ming He, Songling Teng, Yuxiu Sun, Guangbin Wang
Pages: 169-179
Published online on: 03 November 2020

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Article Open Access

Polyphyllin VII induces apoptosis and autophagy via mediating H2O2 levels and the JNK pathway in human osteosarcoma U2OS cells

Xiangde Li, Yun Liu, Shijie Liao, Chengsen Lin, Abu Moro, Jing Liu, Wenyu Feng, Kun Wang, Chunming Wang
Pages: 180-190
Published online on: 23 November 2020

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Article Open Access

Evaluating the biological functions of the prognostic genes identified by the Pathology Atlas in bladder cancer

Yuanbin Chen, Ting Xu, Fei Xie, Liping Wang, Zhijuan Liang, Dan Li, Ye Liang, Kaidong Zhao, Xiangjie Qi, Xuecheng Yang, Wei Jiao
Pages: 191-201
Published online on: 13 November 2020

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Article Open Access

lncRNA GAS5 inhibits malignant progression by regulating macroautophagy and forms a negative feedback regulatory loop with the miR‑34a/mTOR/SIRT1 pathway in colorectal cancer

Hao‑Gang Zhang, Fu‑Jing Wang, Yao Wang, Zi‑Xing Zhao, Peng‑Fei Qiao
Pages: 202-216
Published online on: 26 October 2020

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Article Open Access

Combination of Huanglian Jiedu Decoction and erlotinib delays growth and improves sensitivity of EGFR‑mutated NSCLC cells in vitro and in vivo via STAT3/Bcl‑2 signaling

Xiaowen Zhou, Bojia Liu, Qing Ning, Zhi Xia, Rongling Zhong, Li Zhang, Lei Wu
Pages: 217-229
Published online on: 11 November 2020

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Article Open Access

Targeting eIF4A using rocaglate CR‑1‑31B sensitizes gallbladder cancer cells to TRAIL‑mediated apoptosis through the translational downregulation of c‑FLIP

Yang Cao, Ying He, Litao Yang, Zhou Luan
Pages: 230-238
Published online on: 17 November 2020

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Article Open Access

Microarray expression profile analysis of circular RNAs and their potential regulatory role in bladder carcinoma

Shijie Li, Yiqiao Zhao, Xiaonan Chen
Pages: 239-253
Published online on: 12 November 2020

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Article Open Access

Expression of trefoil factor 3 is decreased in colorectal cancer

Ingrid Espinoza, Sumit Agarwal, Amit Reddy, Veena Shenoy, Charulochana Subramony, Marcelo Sakiyama, Logan Fair, Teja Poosarla, Xinchun Zhou, W. Shannon Orr, Christopher Lahr, Sejong Bae, Sameer Al Diffalha, Upender Manne, Christian R. Gomez
Pages: 254-264
Published online on: 30 October 2020

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Article Open Access

lncRNA CASC9 sponges miR‑758‑3p to promote proliferation and EMT in bladder cancer by upregulating TGF‑β2

Zeng Zhang, Fangfang Chen, Hongrui Zhan, Liping Chen, Qiong Deng, Tiefu Xiong, Yawen Li, Jing Ye
Pages: 265-277
Published online on: 13 November 2020

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Article Open Access

Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment

Shuilian Chen, Xi Chen, Jin Qiu, Pei Chen, Xiaokun Han, Yihui Wu, Jiejie Zhuang, Meng Yang, Chuangran Wu, Nandan Wu, Ying Yang, Jian Ge, Keming Yu, Jing Zhuang
Pages: 278-290
Published online on: 18 November 2020

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Article

Zoledronic acid impairs oral cancer stem cells by reducing CCL3

Sung Hee Lee, Nicole Rigas, Charlotte Ellen Martin, Anthony Nguyen, Mo K. Kang, No‑Hee Park, Reuben H. Kim, Ki‑Hyuk Shin
Pages: 291-298
Published online on: 05 November 2020

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Article

Natural killer cells inhibit breast cancer cell invasion through downregulation of urokinase‑type plasminogen activator

Hao Jin, Hyojeong Choi, Eun‑Sook Kim, Hwan Hee Lee, Hyosun Cho, Aree Moon
Pages: 299-308
Published online on: 06 November 2020

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Article

Cancer type‑SLCO1B3 promotes epithelial‑mesenchymal transition resulting in the tumour progression of non‑small cell lung cancer

Hiroaki Hase, Masaya Aoki, Kentaro Matsumoto, Shuichi Nakai, Toshiyuki Nagata, Aya Takeda, Kazuhiro Ueda, Kentaro Minami, Kaori Kitae, Kentaro Jingushi, Yuko Ueda, Masatatsu Yamamoto, Tatsuhiko Furukawa, Masami Sato, Kazutake Tsujikawa
Pages: 309-316
Published online on: 06 November 2020

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Article

Beige adipocytes contribute to breast cancer progression

Mariana Gantov, Priscila Pagnotta, Cecilia Lotufo, Gustavo Marcelo Rindone, Maria Fernanda Riera, Juan Carlos Calvo, Judith Toneatto
Pages: 317-328
Published online on: 27 October 2020

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Article

Antitumor effect of humanized anti‑tissue factor antibody‑drug conjugate in a model of peritoneal disseminated pancreatic cancer

Ryo Tsumura, Takahiro Anzai, Shino Manabe, Hiroki Takashima, Yoshikatsu Koga, Masahiro Yasunaga, Yasuhiro Matsumura
Pages: 329-336
Published online on: 12 November 2020

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Article

Phenethyl isothiocyanate reduces breast cancer stem cell-like properties by epigenetic reactivation of CDH1

Taolan Zhang, Weijuan Zhang, Meng Hao
Pages: 337-348
Published online on: 19 November 2020

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Article

Utility of flow cytometry and gene rearrangement analysis in tissue and blood of patients with suspected cutaneous T‑cell lymphoma

Julie D. Gibbs, Sophia Ma, Anna Kim, Lucia Seminario‑Vidal, Lubomir Sokol, Hailing Zhang, Xiaohui Zhang, Elizabeth Sagatys, Pei‑Ling Chen, Jane L. Messina
Pages: 349-358
Published online on: 23 November 2020

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Article

Long non‑coding RNA FER1L4 inhibits cell proliferation and promotes cell apoptosis via the PTEN/AKT/p53 signaling pathway in lung cancer

Lanwei Ouyang, Min Yang, Xiaolin Wang, Jidan Fan, Xing Liu, Yong Zhang, Yusheng Shu
Pages: 359-367
Published online on: 19 November 2020

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Article

p53‑p72‑Δ225‑331‑V31I identified in a cholangiocarcinoma cell line promotes migration and invasiveness via the downregulation of claudin‑1 expression and the activation of Cdc42

Janpen Puetkasichonpasutha, Tuangporn Suthiphongchai
Pages: 368-378
Published online on: 27 October 2020

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Article

PD‑L1 and IDO‑1 expression in undifferentiated pleomorphic sarcoma: The associations with tumor infiltrating lymphocytes, dMMR and HLA class I

Shin Ishihara, Yuichi Yamada, Takeshi Iwasaki, Masato Yoshimoto, Yu Toda, Kenichi Kohashi, Hidetaka Yamamoto, Yoshihiro Matsumoto, Yasuharu Nakashima, Yoshinao Oda
Pages: 379-389
Published online on: 05 November 2020

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Article

Dual inhibition of FOXM1 and its compensatory signaling pathway decreased the survival of ovarian cancer cells

Dae Woo Lee, Weonsun Lee, Miyeon Kwon, Hae Nam Lee
Pages: 390-400
Published online on: 11 November 2020

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Correction Open Access

[Corrigendum] STMN1, a prognostic predictor of esophageal squamous cell carcinoma, is a marker of the activation of the PI3K pathway

Wenpeng Jiang, Shiting Huang, Liang Song, Zhou Wang
Pages: 401-402
Published online on: 13 November 2020

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Correction Open Access

[Corrigendum] FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β‑catenin nuclear accumulation

Ke Xu, Zhenhao Zhang, Hua Pei, Huamin Wang, Liang Li, Qianfeng Xia
Pages: 403-403
Published online on: 09 November 2020

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Correction Open Access

[Corrigendum] Tumor‑penetrating peptide fused EGFR single‑domain antibody enhances radiation responses following EGFR inhibition in gastric cancer

Fuzhi Ji, Huizi Sha, Fanyan Meng, Anqing Zhu, Naiqing Ding, Hang Zhang, Hui Xu, Hanqing Qian, Lixia Yu, Qizhan Liu, Baorui Liu
Pages: 404-405
Published online on: 04 November 2020

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Retraction Open Access

[Retracted] Suppression of YAP by DDP disrupts colon tumor progression

Kun Li, Jiwei Guo, Yan Wu, Dan Jin, Hong Jiang, Chengxia Liu, Chengyong Qin
Pages: 406-406
Published online on: 09 November 2020

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Retraction Open Access

[Retracted] Long non-coding RNA MEG3 inhibits cell growth of gliomas by targeting miR-93 and inactivating PI3K/AKT pathway

Ling Zhang, Xin Liang, Yuxiong Li
Pages: 407-407
Published online on: 27 October 2020

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Retraction Open Access

[Retracted] Norcantharidin reverses cisplatin resistance and inhibits the epithelial mesenchymal transition of human non‑small lung cancer cells by regulating the YAP pathway

Dan Jin, Yan Wu, Cuijie Shao, Yong Gao, Deqiang Wang, Jiwei Guo
Pages: 408-408
Published online on: 02 November 2020

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

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Article Number: 164
Published online on: 24 July 2026

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