Open Access

Potential roles of exosome non‑coding RNAs in cancer chemoresistance (Review)

  • Authors:
    • Yueyue Wang
    • Qian Liu
    • Fengchao Wang
  • View Affiliations

  • Published online on: December 8, 2020     https://doi.org/10.3892/or.2020.7887
  • Pages: 439-447
  • Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Multiple studies have demonstrated chemoresistance in multiple types of tumor, which limits the effectiveness of cancer treatments. Chemoresistance often contributes to cancer relapse. Non‑coding RNAs, are a group of regulatory RNAs, that are involved in tumor drug resistance. Exosomes, membranous vesicles secreted by cells, are reported to mediate cell‑to‑cell communication, including in cancer. Furthermore, exosomal non‑coding RNAs have been reported to mediate chemoresistance via exchange of biological information. In the present review, the main roles of exosomal non‑coding RNAs, including micro(mi) RNAs, long non‑coding (lnc) RNAs, and circular (circ) RNAs in cancer are described and their potential roles in chemoresistance in various types of cancer are also discussed.
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February-2021
Volume 45 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Wang Y, Liu Q and Wang F: Potential roles of exosome non‑coding RNAs in cancer chemoresistance (Review). Oncol Rep 45: 439-447, 2021
APA
Wang, Y., Liu, Q., & Wang, F. (2021). Potential roles of exosome non‑coding RNAs in cancer chemoresistance (Review). Oncology Reports, 45, 439-447. https://doi.org/10.3892/or.2020.7887
MLA
Wang, Y., Liu, Q., Wang, F."Potential roles of exosome non‑coding RNAs in cancer chemoresistance (Review)". Oncology Reports 45.2 (2021): 439-447.
Chicago
Wang, Y., Liu, Q., Wang, F."Potential roles of exosome non‑coding RNAs in cancer chemoresistance (Review)". Oncology Reports 45, no. 2 (2021): 439-447. https://doi.org/10.3892/or.2020.7887