Journal Articles

Review Open Access

Dose adjustment for tyrosine kinase inhibitors in non‑small cell lung cancer patients with hepatic or renal function impairment (Review)

Dehua Zhao, Jing Chen, Xiaoqing Long, Jisheng Wang

Pages: 413-426 Published online on: 27 November 2020
Review

IGFBP2 in cancer: Pathological role and clinical significance (Review)

Lai‑Feng Wei, Xue‑Fen Weng, Xu‑Chun Huang, Yu‑Hui Peng, Hai‑Peng Guo, Yi‑Wei Xu

Pages: 427-438 Published online on: 09 December 2020
Review Open Access

Potential roles of exosome non‑coding RNAs in cancer chemoresistance (Review)

Yueyue Wang, Qian Liu, Fengchao Wang

Pages: 439-447 Published online on: 08 December 2020
Article

Heat shock protein 90 as a molecular target for therapy in oral squamous cell carcinoma: Inhibitory effects of 17‑DMAG and ganetespib on tumor cells

Naoki Shiraishi, Takeshi Onda, Kamichika Hayashi, Kaoru Onidani, Katsuhito Watanabe, Shoichi Sekikawa, Takahiko Shibahara

Pages: 448-458 Published online on: 30 November 2020
Article Open Access

Zoledronic acid re‑sensitises gefitinib‑resistant lung cancer cells by inhibiting the JAK/STAT3 signalling pathway and reversing epithelial‑mesenchymal transition

Xibiao Yang, Yuan Gao, Qiang Liu, Lin Wan, Honglian Liu, Weiwei Bian, Yun Du, Chuying Huang

Pages: 459-468 Published online on: 03 December 2020
Article Open Access

lncRNA FOXP4‑AS1 predicts poor prognosis and accelerates the progression of mantle cell lymphoma through the miR‑423‑5p/NACC1 pathway

Hong‑Fang Tao, Jia‑Xin Shen, Zhan‑Wen Hou, Shao‑Yan Chen, Yong‑Zhong Su, Jian‑Lin Fang

Pages: 469-480 Published online on: 11 December 2020
Article Open Access

KRT7 promotes epithelial‑mesenchymal transition in ovarian cancer via the TGF‑β/Smad2/3 signaling pathway

Qiang An, Ting Liu, Ming‑Yang Wang, Yu‑Jia Yang, Zhen‑Dong Zhang, Zhen‑Jiang Liu, Bing Yang

Pages: 481-492 Published online on: 08 December 2020
Article Open Access

Novel EGFR‑bispecific recombinant immunotoxin based on cucurmosin shows potent anti‑tumor efficiency in vitro

Caiyun Zhang, Yumei Cai, Xiaoxue Dai, Jingyu Wu, Yinxiang Lan, Huajin Zhang, Mengni Lu, Junhong Liu, Jieming Xie

Pages: 493-500 Published online on: 02 December 2020
Article Open Access

Hsa_circ_0016760 exacerbates the malignant development of non‑small cell lung cancer by sponging miR‑145‑5p/FGF5

Zheng Zhu, Qiyong Wu, Ming Zhang, Jichun Tong, Bin Zhong, Kai Yuan

Pages: 501-512 Published online on: 14 December 2020
Article Open Access

Polyphyllin VII induces mitochondrial apoptosis by regulating the PP2A/AKT/DRP1 signaling axis in human ovarian cancer

Liubiqi Zhao, Zongyu Liu, Xinyue Deng, Jiabin Wang, Liankun Sun, Limei Fan, Yong Zhang

Pages: 513-522 Published online on: 02 December 2020
Article Open Access

TELO2 induced progression of colorectal cancer by binding with RICTOR through mTORC2

Zheng Guo, Xiufang Zhang, Huabin Zhu, Nanying Zhong, Xiaoning Luo, Yu Zhang, Fuping Tu, Jinghua Zhong, Xiangcai Wang, Jue He, Li Huang

Pages: 523-534 Published online on: 09 December 2020
Article Open Access

Identification of in vitro and in vivo oncolytic effect in colorectal cancer cells by Orf virus strain NA1/11

Daxiang Chen, Ruixue Wang, Mingjian Long, Wei Li, Bin Xiao, Hao Deng, Kongyan Weng, Daoyuan Gong, Fang Liu, Shuhong Luo, Wenbo Hao

Pages: 535-546 Published online on: 08 December 2020
Article Open Access

Multifunctional nanoparticle PEG‑Ce6‑Gd for MRI‑guided photodynamic therapy

Dan Xu, Aju Baidya, Kai Deng, Yu‑Shuang Li, Bo Wu, Hai‑Bo Xu

Pages: 547-556 Published online on: 27 November 2020
Article Open Access

TCF7 knockdown inhibits the imatinib resistance of chronic myeloid leukemia K562/G01 cells by neutralizing the Wnt/β‑catenin/TCF7/ABC transporter signaling axis

Hui Zhang, Yonghong Wang, Hao Yang, Zhenglan Huang, Xin Wang, Wenli Feng

Pages: 557-568 Published online on: 27 November 2020
Article Open Access

miRNA‑199b‑3p suppresses growth and progression of ovarian cancer via the CHK1/E‑cadherin/EMT signaling pathway by targeting ZEB1

Liqun Wei, Yuanqi He, Shuhong Bi, Xiaoxiao Li, Jianzhong Zhang, Shihong Zhang

Pages: 569-581 Published online on: 11 December 2020
Article Open Access

Selection of tumor‑resistant variants following sustained natural killer cell‑mediated immune stress

Thibault Carré, Jerome Thiery, Bassam Janji, Stéphane Terry, Gwendoline Gros, Guillaume Meurice, Claudine Kieda, Daniel Olive, Salem Chouaib

Pages: 582-594 Published online on: 27 November 2020
Article Open Access

Genetic deletion of Rnd3 suppresses apoptosis through NF‑κB signaling in the brain

Huimin Dong, Qian Sun, Ying Zhang, Yuntao Li, Fan'en Yuan, Shanping Mao, Baohui Liu

Pages: 595-605 Published online on: 08 December 2020
Article Open Access

Effect of claudin 1 on cell proliferation, migration and apoptosis in human cervical squamous cell carcinoma

Zhen Shen, Weiguo Song, Lili Qian, Jing Zhu, Yuebo Li, Min Li, Tianjiao Zhang, Weidong Zhao, Ying Zhou, Xingsheng Yang

Pages: 606-618 Published online on: 08 December 2020
Article Open Access

Long non‑coding RNA AC245100.4 promotes prostate cancer tumorigenesis via the microRNA‑145‑5p/RBBP5 axis

Hui Xie, Jiabin Zhao, Jiahui Wan, Jianing Zhao, Qianqian Wang, Xu Yang, Weiyu Yang, Ping Lin, Xiaoguang Yu

Pages: 619-629 Published online on: 10 December 2020
Article Open Access

Garcinol inhibits the proliferation of endometrial cancer cells by inducing cell cycle arrest

Min Zhang, Qinsheng Lu, Huomei Hou, Dingqian Sun, Miaojuan Chen, Fen Ning, Peihuang Wu, Dan Wei, Yaoyun Duan, Yue Pan, Gendie E. Lash

Pages: 630-640 Published online on: 15 December 2020
Article Open Access

Expression and role of fibroblast activation protein α in acute myeloid leukemia

Shuchong Mei, Yuan Zhang, Li Yu, Guoan Chen, Fuming Zi

Pages: 641-651 Published online on: 30 November 2020
Article Open Access

Osteopontin‑c isoform inhibition modulates ovarian cancer cell cisplatin resistance, viability and plasticity

Mariana Concentino Menezes Brum, Isabella Dos Santos Guimaraes, Luciana Bueno Ferreira, Leticia Batista Azevedo Rangel, Raquel Ciuvalschi Maia, Gabriela Nestal De Moraes, Etel R.P. Gimba

Pages: 652-664 Published online on: 01 December 2020
Article Open Access

Enhancement of cisplatin sensitivity in human breast cancer MCF-7 cell line through BiP and 14-3-3ζ co-knockdown

Tahereh Kashkoulinejad-Kouhi, Shahrokh Safarian, Blanca Arnaiz, Laura Saa

Pages: 665-679 Published online on: 14 December 2020
Article Open Access

Novel quinazolinone MJ‑33 induces AKT/mTOR‑mediated autophagy‑associated apoptosis in 5FU‑resistant colorectal cancer cells

Hai‑Anh Ha, Jo‑Hua Chiang, Fuu‑Jen Tsai, Da‑Tian Bau, Yu‑Ning Juan, Yu‑Hsiang Lo, Mann‑Jen Hour, Jai‑Sing Yang

Pages: 680-692 Published online on: 03 December 2020
Article Open Access

Involvement of Blnk and Foxo1 in tumor suppression in BCR‑ABL1‑transformed pro‑B cells

Ping Zhang, Yang Wang, Mengting Qin, Dandan Li, Woodvine Otieno Odhiambo, Meng Yuan, Zhuangwei Lv, Chengcheng Liu, Yunfeng Ma, Yanying Dong, Yanhong Ji

Pages: 693-705 Published online on: 08 December 2020
Article Open Access

miRNA‑490‑3p promotes the metastatic progression of invasive ductal carcinoma

Ning Lu, Mei Zhang, Lu Lu, Yan‑Zhao Liu, Hai‑Hong Zhang, Xiao‑Dong Liu

Pages: 706-716 Published online on: 02 December 2020
Article Open Access

Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF‑κB signaling pathway

Anqi Zeng, Xin Liang, Shaomi Zhu, Chi Liu, Shu Wang, Qinxiu Zhang, Junning Zhao, Linjiang Song

Pages: 717-727 Published online on: 09 December 2020
Article

Long non‑coding RNA CASC19 promotes glioma progression by modulating the miR‑454‑3p/RAB5A axis and is associated with unfavorable MRI features

Yong‑Juan Wu, Qing‑Song Yang, Hui Chen, Jiang‑Tao Wang, Wan‑Bi Wang, Ling Zhou

Pages: 728-737 Published online on: 01 December 2020
Article

Effects of an elemental diet, Elental®, may differ between healthy oral cells and oral cancer cells

Koji Harada, Tarannum Ferdous, Kenji Watanabe, Yoichi Mizukami, Katsuaki Mishima

Pages: 738-751 Published online on: 11 December 2020
Article

Targeting the mitogen‑activated protein kinase kinase and protein kinase A pathways overcomes acquired resistance to Selumetinib in low‑grade glioma cells

Linda Melotti, Daniela Meco, Alessandra Battaglia, Alexia Buzzonetti, Maurizio Martini, Antonio Ruggiero, Giovanni Scambia, Riccardo Riccardi

Pages: 752-763 Published online on: 25 November 2020
Article

microRNA‑196a‑3p inhibits cell proliferation and promotes cell apoptosis by targeting ADP ribosylation factor 4 in diffuse large B‑cell lymphoma

Jianhong Fu, Xiaoli Lou, Shan Wan, Xin Zhao, Zhi Chen, Minsheng Zhu, Lingchuan Guo, Depei Wu, Shouli Wang

Pages: 764-775 Published online on: 16 December 2020
Article

EV20‑sss‑vc/MMAF, an HER‑3 targeting antibody‑drug conjugate displays antitumor activity in liver cancer

Daniela D'Agostino, Roberta Gentile, Sara Ponziani, Giulia Di Vittorio, Francesco Dituri, Gianluigi Giannelli, Cosmo Rossi, Liberato Marzullo, Francesco Giansanti, Vincenzo De Laurenzi, Stefano Iacobelli, Rodolfo Ippoliti, Emily Capone, Gianluca Sala

Pages: 776-785 Published online on: 09 December 2020
Correction Open Access

[Corrigendum] CCL22 and IL‑37 inhibit the proliferation and epithelial‑mesenchymal transition process of NSCLC A549 cells

Yu-Hua Chen, Bi-Yun Zhou, Xian-Jing Wu, Jun-Fa Xu, Jun‑Ai Zhang, Yong-Hua Chen, Si-Si Liang

Pages: 786-786 Published online on: 16 December 2020
Correction Open Access

[Corrigendum] Ski prevents TGF‑β‑induced EMT and cell invasion by repressing SMAD‑dependent signaling in non‑small cell lung cancer

Haiping Yang, Lei Zhan, Tianjie Yang, Longqiang Wang, Chang Li, Jun Zhao, Zhe Lei, Xiangdong Li, Hong-Tao Zhang

Pages: 787-788 Published online on: 25 November 2020
Correction Open Access

[Corrigendum] miRNA‑183‑5p.1 promotes the migration and invasion of gastric cancer AGS cells by targeting TPM1

Jun Lin, Juan Shen, Hao Yue, Zhongwei Cao

Pages: 789-790 Published online on: 16 December 2020
Correction Open Access

[Corrigendum] Epithelial mesenchymal transition induced by the CXCL9/CXCR3 axis through AKT activation promotes invasion and metastasis in tongue squamous cell carcinoma

Ziliang Li, Jianqi Liu, Lei Li, Shuai Shao, Jianhua Wu, Li Bian, Yongwen He

Pages: 791-792 Published online on: 03 December 2020
Correction Open Access

[Corrigendum] Downregulation of nucleolar and spindle‑associated protein 1 expression suppresses cell migration, proliferation and invasion in renal cell carcinoma

Lu Fang, Meng Zhang, Lei Chen, Hu Xiong, Yukun Ge, Wei Lu, Xun Wu, Baoli Heng, Dexin Yu, Song Wu

Pages: 793-793 Published online on: 30 November 2020
Journal Cover

February-2021
Volume 45 Issue 2

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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