|
1
|
Siegel RL, Miller KD, Fuchs HE and Jemal
A: Cancer statistics, 2022. CA Cancer J Clin. 72:7–33. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Hiley CT, Le Quesne J, Santis G, Sharpe R,
de Castro DG, Middleton G and Swanton C: Challenges in molecular
testing in non-small-cell lung cancer patients with advanced
disease. Lancet. 388:1002–1011. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Del Re M, Crucitta S, Gianfilippo G,
Passaro A, Petrini I, Restante G, Michelucci A, Fogli S, de Marinis
F, Porta C, et al: Understanding the mechanisms of resistance in
EGFR-positive NSCLC: From tissue to liquid biopsy to guide
treatment strategy. Int J Mol Sci. 20:39512019. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Doval DC, Desai CJ and Sahoo TP:
Molecularly targeted therapies in non-small cell lung cancer: The
evolving role of tyrosine kinase inhibitors. Indian J Cancer. 56
(Suppl):S23–S30. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kelaidi C, Makis A, Petrikkos L, Antoniadi
K, Selenti N, Tzotzola V, Ioannidou ED, Tsitsikas K, Kitra V,
Kalpini-Mavrou A, et al: Bone marrow failure in Fanconi anemia:
Clinical and genetic spectrum in a cohort of 20 pediatric patients.
J Pediatr Hematol Oncol. 41:612–617. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Engel NW, Schliffke S, Schüller U, Frenzel
C, Bokemeyer C, Kubisch C and Lessel D: Fatal myelotoxicity
following palliative chemotherapy with cisplatin and gemcitabine in
a patient with stage IV cholangiocarcinoma linked to post mortem
diagnosis of Fanconi anemia. Front Oncol. 9:4202019. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Katsuki Y and Takata M: Defects in
homologous recombination repair behind the human diseases: FA and
HBOC. Endocr Relat Cancer. 23:T19–T37. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Dong H, Nebert DW, Bruford EA, Thompson
DC, Joenje H and Vasiliou V: Update of the human and mouse Fanconi
anemia genes. Hum Genomics. 9:322015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kottemann MC and Smogorzewska A: Fanconi
anaemia and the repair of Watson and Crick DNA crosslinks. Nature.
493:356–363. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Joo W, Xu G, Persky NS, Smogorzewska A,
Rudge DG, Buzovetsky O, Elledge SJ and Pavletich NP: Structure of
the FANCI-FANCD2 complex: Insights into the Fanconi anemia DNA
repair pathway. Science. 333:312–316. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Sondalle SB, Longerich S, Ogawa LM, Sung P
and Baserga SJ: Fanconi anemia protein FANCI functions in ribosome
biogenesis. Proc Natl Acad Sci USA. 116:2561–2570. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Meetei AR, de Winter JP, Medhurst AL,
Wallisch M, Waisfisz Q, van de Vrugt HJ, Oostra AB, Yan Z, Ling C,
Bishop CE, et al: A novel ubiquitin ligase is deficient in Fanconi
anemia. Nat Genet. 35:165–170. 2003. View
Article : Google Scholar : PubMed/NCBI
|
|
15
|
Smogorzewska A, Matsuoka S, Vinciguerra P,
McDonald ER III, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K,
D'Andrea AD and Elledge SJ: Identification of the FANCI protein, a
monoubiquitinated FANCD2 paralog required for DNA repair. Cell.
129:289–301. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Paulo P, Maia S, Pinto C, Pinto P,
Monteiro A, Peixoto A and Teixeira MR: Targeted next generation
sequencing identifies functionally deleterious germline mutations
in novel genes in early-onset/familial prostate cancer. PLoS Genet.
14:e10073552018. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Xie S, Jiang X, Zhang J, Xie S, Hua Y,
Wang R and Yang Y: Identification of significant gene and pathways
involved in HBV-related hepatocellular carcinoma by bioinformatics
analysis. PeerJ. 7:e74082019. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zheng P and Li L: FANCI cooperates with
IMPDH2 to promote lung adenocarcinoma tumor growth via a
MEK/ERK/MMPs pathway. Onco Targets Ther. 13:451–463. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Machida YJ, Machida Y, Chen Y, Gurtan AM,
Kupfer GM, D'Andrea AD and Dutta A: UBE2T is the E2 in the Fanconi
anemia pathway and undergoes negative autoregulation. Mol Cell.
23:589–596. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Longerich S, San Filippo J, Liu D and Sung
P: FANCI binds branched DNA and is monoubiquitinated by
UBE2T-FANCL. J Biol Chem. 284:23182–23186. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Ueki T, Park JH, Nishidate T, Kijima K,
Hirata K, Nakamura Y and Katagiri T: Ubiquitination and
downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T
overexpression in human breast cancer cells. Cancer Res.
69:8752–8760. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Zhu X, Li T, Niu X, Chen L and Ge C:
Identification of UBE2T as an independent prognostic biomarker for
gallbladder cancer. Oncol Lett. 20:442020. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Sun J, Zhu Z, Li W, Shen M, Cao C, Sun Q,
Guo Z, Liu L and Wu D: UBE2T-regulated H2AX monoubiquitination
induces hepatocellular carcinoma radioresistance by facilitating
CHK1 activation. J Exp Clin Cancer Res. 39:2222020. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wu ZH, Zhang YJ and Sun HY: High ubiquitin
conjugating enzyme E2 T mRNA expression and its prognostic
significance in lung adenocarcinoma: A study based on the TCGA
database. Medicine (Baltimore). 99:e185432020. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Yin H, Wang X, Zhang X, Zeng Y, Xu Q, Wang
W, Zhou F and Zhou Y: UBE2T promotes radiation resistance in
non-small cell lung cancer via inducing epithelial-mesenchymal
transition and the ubiquitination-mediated FOXO1 degradation.
Cancer Lett. 494:121–131. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hay ED: An overview of
epithelio-mesenchymal transformation. Acta Anat (Basel). 154:8–20.
1995. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Thiery JP: Epithelial-mesenchymal
transitions in development and pathologies. Curr Opin Cell Biol.
15:740–746. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zhao L, Sun H, Kong H, Chen Z, Chen B and
Zhou M: The lncrna-TUG1/EZH2 axis promotes pancreatic cancer cell
proliferation, migration and EMT phenotype formation through
sponging Mir-382. Cell Physiol Biochem. 42:2145–2158. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Wang X, Yin H, Zhang H, Hu J, Lu H, Li C,
Cao M, Yan S and Cai L: NF-κB-driven improvement of EHD1
contributes to erlotinib resistance in EGFR-mutant lung cancers.
Cell Death Dis. 9:4182018. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Han D, Wang L, Chen B, Zhao W, Liang Y, Li
Y, Zhang H, Liu Y, Wang X, Chen T, et al: USP1-WDR48 deubiquitinase
complex enhances TGF-β induced epithelial-mesenchymal transition of
TNBC cells via stabilizing TAK1. Cell Cycle. 20:320–331. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Cao J, Yuan P, Wang Y, Xu J, Yuan X, Wang
Z, Lv W and Hu J: Survival rates after lobectomy, segmentectomy,
and wedge resection for non-small cell lung cancer. Ann Thorac
Surg. 105:1483–1491. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Giaj-Levra N, Borghetti P, Bruni A,
Ciammella P, Cuccia F, Fozza A, Franceschini D, Scotti V, Vagge S
and Alongi F: Current radiotherapy techniques in NSCLC: Challenges
and potential solutions. Expert Rev Anticancer Ther. 20:387–402.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Rozelle AL, Cheun Y, Vilas CK, Koag MC and
Lee S: DNA interstrand cross-links induced by the major oxidative
adenine lesion 7,8-dihydro-8-oxoadenine. Nat Commun. 12:18972021.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Yang Y, Guo T, Liu R, Ke H, Xu W, Zhao S
and Qin Y: FANCL gene mutations in premature ovarian insufficiency.
Hum Mutat. 41:1033–1041. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Ceccaldi R, Sarangi P and D'Andrea AD: The
Fanconi anaemia pathway: New players and new functions. Nat Rev Mol
Cell Biol. 17:337–349. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Zhang X, Lu X, Akhter S, Georgescu MM and
Legerski RJ: FANCI is a negative regulator of Akt activation. Cell
Cycle. 15:1134–1143. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhang W, Zhang Y, Yang Z, Liu X, Yang P,
Wang J, Hu K, He X, Zhang X and Jing H: High expression of UBE2T
predicts poor prognosis and survival in multiple myeloma. Cancer
Gene Ther. 26:347–355. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Liu LP, Yang M, Peng QZ, Li MY, Zhang YS,
Guo YH, Chen Y and Bao SY: UBE2T promotes hepatocellular carcinoma
cell growth via ubiquitination of p53. Biochem Biophys Res Commun.
493:20–27. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Lioulia E, Mokos P, Panteris E and Dafou
D: UBE2T promotes β-catenin nuclear translocation in hepatocellular
carcinoma through MAPK/ERK-dependent activation. Mol Oncol.
16:1694–1713. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Zhu J, Ao H, Liu M, Cao K and Ma J: UBE2T
promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung
adenocarcinoma. J Transl Med. 19:3742021. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Nepal M, Che R, Ma C, Zhang J and Fei P:
FANCD2 and DNA damage. Int J Mol Sci. 18:18042017. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Sato K, Toda K, Ishiai M, Takata M and
Kurumizaka H: DNA robustly stimulates FANCD2 monoubiquitylation in
the complex with FANCI. Nucleic Acids Res. 40:4553–4561. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Wang S, Wang R, Peralta C, Yaseen A and
Pavletich NP: Structure of the FA core ubiquitin ligase closing the
ID clamp on DNA. Nat Struct Mol Biol. 28:300–309. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
van Twest S, Murphy VJ, Hodson C, Tan W,
Swuec P, O'Rourke JJ, Heierhorst J, Crismani W and Deans AJ:
Mechanism of ubiquitination and deubiquitination in the Fanconi
anemia pathway. Mol Cell. 65:247–259. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Beck M, Schmidt A, Malmstroem J, Claassen
M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J and
Aebersold R: The quantitative proteome of a human cell line. Mol
Syst Biol. 7:5492011. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Oka Y, Bekker-Jensen S and Mailand N:
Ubiquitin-like protein UBL5 promotes the functional integrity of
the Fanconi anemia pathway. EMBO J. 34:1385–1398. 2015. View Article : Google Scholar : PubMed/NCBI
|
