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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Correction Open Access

[Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia

  • Authors:
    • Na Chen
    • Lili Feng
    • Huiting Qu
    • Kang Lu
    • Peipei Li
    • Xiao Lv
    • Xin Wang
  • View Affiliations / Copyright

    Affiliations: Department of Hematology, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China
    Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 107
    |
    Published online on: July 2, 2025
       https://doi.org/10.3892/or.2025.8940
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Article

View Figures

Figure 1

Expression of pSTAT3 protein and
miRNAs in CLL patients and healthy controls. (A) The expression of
the pSTAT3 protein was detected in 20 samples with upregulation of
IL-9 (C), but none was detected in 10 PBMC from normal controls
(N). (B) Relative density analysis of pSTAT3 protein bands.
**P<0.0001. (C) RT-qPCR analysis of miR-155 expression in CLL
patients and healthy controls. *P=0.0308. (D) RT-qPCR analysis of
miR-21 expression in patient samples and healthy donors.
*P=0.0398.

Figure 2

Effects of rIL-9 on pSTAT3 and IL-9
production in MEC-1 cells. (A) MEC-1 cells were pretreated with or
without WP1066 for 48 h and then were incubated with rIL-9 for
different times. STAT3 phosphorylation and IL-9 production in MEC-1
cells increased with the stimulation of rIL-9 in a time-dependent
manner. WP1066, the STAT3 inhibitor, could markedly suppress the
effects of rIL-9 on MEC-1 cells. (B) Relative density analysis of
pSTAT3 protein bands, which were cultured with rIL-9 for 120 min.
**P<0.0001. (C) Relative density analysis of IL-9 protein bands,
which were treated with rIL-9 for 120 min. **P<0.0001. (D)
Expression of pSTAT3 and IL-9 were detected by western blotting,
with the single band size of 88 and 14 kDa, in peripheral blood
mononuclear cells (PBMCs) from healthy samples and human CLL cell
line MEC-1 after co-culture with rIL-9 for 120 min. (E and F)
STAT3-knockdown cells exhibited significantly lower IL-9 expression
in comparison to the cells transfected with negative control siRNA
after co-culture with rIL-9 for 120 min. **P<0.0001.

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Copy and paste a formatted citation
Spandidos Publications style
Chen N, Feng L, Qu H, Lu K, Li P, Lv X and Wang X: [Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia. Oncol Rep 54: 107, 2025.
APA
Chen, N., Feng, L., Qu, H., Lu, K., Li, P., Lv, X., & Wang, X. (2025). [Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia. Oncology Reports, 54, 107. https://doi.org/10.3892/or.2025.8940
MLA
Chen, N., Feng, L., Qu, H., Lu, K., Li, P., Lv, X., Wang, X."[Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia". Oncology Reports 54.3 (2025): 107.
Chicago
Chen, N., Feng, L., Qu, H., Lu, K., Li, P., Lv, X., Wang, X."[Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia". Oncology Reports 54, no. 3 (2025): 107. https://doi.org/10.3892/or.2025.8940
Copy and paste a formatted citation
x
Spandidos Publications style
Chen N, Feng L, Qu H, Lu K, Li P, Lv X and Wang X: [Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia. Oncol Rep 54: 107, 2025.
APA
Chen, N., Feng, L., Qu, H., Lu, K., Li, P., Lv, X., & Wang, X. (2025). [Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia. Oncology Reports, 54, 107. https://doi.org/10.3892/or.2025.8940
MLA
Chen, N., Feng, L., Qu, H., Lu, K., Li, P., Lv, X., Wang, X."[Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia". Oncology Reports 54.3 (2025): 107.
Chicago
Chen, N., Feng, L., Qu, H., Lu, K., Li, P., Lv, X., Wang, X."[Corrigendum] Overexpression of IL‑9 induced by STAT3 phosphorylation is mediated by miR‑155 and miR‑21 in chronic lymphocytic leukemia". Oncology Reports 54, no. 3 (2025): 107. https://doi.org/10.3892/or.2025.8940
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