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Adeno-associated virus vector mediated transduction of primary normal human breast epithelial cells.

  • Authors:
    • J Yang
    • Y Hirokawa
    • C Dougherty
    • P Colosi
    • J H Yang
    • S Nandi

  • View Affiliations

  • Published online on: July 1, 1998     https://doi.org/10.3892/or.5.4.793
  • Pages: 793-800
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

Cultured human breast epithelial cells from reduction mammoplasty specimens were transduced using an adeno-associated virus vector encoding the marker gene E. coli -galactosidase. Subconfluent, growing, breast epithelial cells were more easily transduced than confluent, quiescent, cells. Transduction of non-dividing confluent cells could be greatly increased by ultraviolet light-induced DNA damage or by prior exposure to the DNA synthesis inhibitor hydroxyurea. The effects of ultraviolet light and hydroxyurea on transduction were additive when these agents were applied together.

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Jul-Aug 1998
Volume 5 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Impact Factor: 4.2
  • Ranked Oncology
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  • CiteScore: 8.4
  • CiteScore Rank: Q1: #68/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.786
  • SCImago Journal Rank (SJR): 0.812
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Spandidos Publications style
Yang J, Hirokawa Y, Dougherty C, Colosi P, Yang J and Nandi S: Adeno-associated virus vector mediated transduction of primary normal human breast epithelial cells.. Oncol Rep 5: 793-800, 1998
APA
Yang, J., Hirokawa, Y., Dougherty, C., Colosi, P., Yang, J., & Nandi, S. (1998). Adeno-associated virus vector mediated transduction of primary normal human breast epithelial cells.. Oncology Reports, 5, 793-800. https://doi.org/10.3892/or.5.4.793
MLA
Yang, J., Hirokawa, Y., Dougherty, C., Colosi, P., Yang, J., Nandi, S."Adeno-associated virus vector mediated transduction of primary normal human breast epithelial cells.". Oncology Reports 5.4 (1998): 793-800.
Chicago
Yang, J., Hirokawa, Y., Dougherty, C., Colosi, P., Yang, J., Nandi, S."Adeno-associated virus vector mediated transduction of primary normal human breast epithelial cells.". Oncology Reports 5, no. 4 (1998): 793-800. https://doi.org/10.3892/or.5.4.793