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Detection of serum p53 antibodies in patients with esophageal squamous cell carcinoma: correlation with clinicopathologic features and tumor markers.

  • Authors:
    • H Shimada
    • K Nakajima
    • T Ochiai
    • Y Koide
    • S I Okazumi
    • H Matsubara
    • A Takeda
    • Y Miyazawa
    • M Arima
    • K Isono

  • View Affiliations

  • Published online on: July 1, 1998     https://doi.org/10.3892/or.5.4.871
  • Pages: 871-875
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Abstract

The significance of serum p53-Abs in patients with esophageal squamous cell carcinoma was determined. Examination of clinicopathological features and assessment of tumor marker sensitivities of carcinoembryonic antigen (CEA), squamous cell carcinoma antigen (SCC-Ag) and CYFRA21-1 were performed. Thirty-three (58%) of 57 patients were positive for serum p53-Abs, however, no relation with cancer progression existed. Fourteen of the 33 sero-positive patients revealed normal levels of all tumor markers tested. Thus, serum p53-Abs appears to be a useful marker for the detection of esophageal squamous cell carcinoma.

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Jul-Aug 1998
Volume 5 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Shimada H, Nakajima K, Ochiai T, Koide Y, Okazumi S, Matsubara H, Takeda A, Miyazawa Y, Arima M, Isono K, Isono K, et al: Detection of serum p53 antibodies in patients with esophageal squamous cell carcinoma: correlation with clinicopathologic features and tumor markers.. Oncol Rep 5: 871-875, 1998
APA
Shimada, H., Nakajima, K., Ochiai, T., Koide, Y., Okazumi, S., Matsubara, H. ... Isono, K. (1998). Detection of serum p53 antibodies in patients with esophageal squamous cell carcinoma: correlation with clinicopathologic features and tumor markers.. Oncology Reports, 5, 871-875. https://doi.org/10.3892/or.5.4.871
MLA
Shimada, H., Nakajima, K., Ochiai, T., Koide, Y., Okazumi, S., Matsubara, H., Takeda, A., Miyazawa, Y., Arima, M., Isono, K."Detection of serum p53 antibodies in patients with esophageal squamous cell carcinoma: correlation with clinicopathologic features and tumor markers.". Oncology Reports 5.4 (1998): 871-875.
Chicago
Shimada, H., Nakajima, K., Ochiai, T., Koide, Y., Okazumi, S., Matsubara, H., Takeda, A., Miyazawa, Y., Arima, M., Isono, K."Detection of serum p53 antibodies in patients with esophageal squamous cell carcinoma: correlation with clinicopathologic features and tumor markers.". Oncology Reports 5, no. 4 (1998): 871-875. https://doi.org/10.3892/or.5.4.871