Expression of type I interferon receptor in renal cell carcinoma.

  • Authors:
    • L Morell-Quadreny
    • B Fenollosa-Entrena
    • F Clar-Blanch
    • S Navarro-Fos
    • A Llombart-Bosch
  • View Affiliations

  • Published online on: May 1, 1999     https://doi.org/10.3892/or.6.3.639
  • Pages: 639-681
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Abstract

Immunohistochemical analysis of INF-R was performed on 110 renal tumors, 25 peritumoral kidney tissues and 10 lymph node metastases. Pathological material was previously studied and classified according to predominant cell type, stage and grade. A statistical analysis was made in order to determine to what extent the immunoexpression of INF-R differed in relation to the histological variables studied. All peritumoral kidney sections, 89/110 tumors and 9/10 metastases proved positive. Membranous expression was related to clear cell carcinomas. Type I INF-R is expressed in RCC, independent of tumor stage and grade, as well as sex, age and survival. INF-R is widely expressed in RCC in any tumoral type, and its expression is preserved in metastatic disease, which may help to target those patients who could benefit from INF therapy.

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May-Jun 1999
Volume 6 Issue 3

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Morell-Quadreny L, Fenollosa-Entrena B, Clar-Blanch F, Navarro-Fos S and Llombart-Bosch A: Expression of type I interferon receptor in renal cell carcinoma.. Oncol Rep 6: 639-681, 1999
APA
Morell-Quadreny, L., Fenollosa-Entrena, B., Clar-Blanch, F., Navarro-Fos, S., & Llombart-Bosch, A. (1999). Expression of type I interferon receptor in renal cell carcinoma.. Oncology Reports, 6, 639-681. https://doi.org/10.3892/or.6.3.639
MLA
Morell-Quadreny, L., Fenollosa-Entrena, B., Clar-Blanch, F., Navarro-Fos, S., Llombart-Bosch, A."Expression of type I interferon receptor in renal cell carcinoma.". Oncology Reports 6.3 (1999): 639-681.
Chicago
Morell-Quadreny, L., Fenollosa-Entrena, B., Clar-Blanch, F., Navarro-Fos, S., Llombart-Bosch, A."Expression of type I interferon receptor in renal cell carcinoma.". Oncology Reports 6, no. 3 (1999): 639-681. https://doi.org/10.3892/or.6.3.639