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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-Jun 1999 Volume 6 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Bcl-2 protects against beta-lapachone-mediated caspase 3 activation and apoptosis in human myeloid leukemia (HL-60) cells.

S M Planchon, S M Wuerzberger-Davis, J J Pink, K A Robertson, W G Bornmann, D A Boothman
Pages: 485-577
Published online on: 01 May 1999

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Article

Is digitalis a therapy for breast carcinoma?

B Stenkvist
Pages: 493-499
Published online on: 01 May 1999

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Article

Loci for efficient detection of microsatellite instability in hereditary non-polyposis colorectal cancer.

M L Frazier, F A Sinicrope, C I Amos, K R Cleary, P M Lynch, B Levin, R Luthra
Pages: 497-1002
Published online on: 01 May 1999

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Article

Spontaneous conversion to estrogen receptor expression by the human breast epithelial cell line, MCF-10A.

M A Lane, L Romagnoli, B Cruise, G M Cohn
Pages: 507-518
Published online on: 01 May 1999

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Article

Analysis of radiation pneumonitis and radiation-induced lung fibrosis in breast cancer patients after breast conservation treatment.

A Nishioka, Y Ogawa, N Hamada, M Terashima, T Inomata, S Yoshida
Pages: 513-520
Published online on: 01 May 1999

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Article

Expression of platelet-derived endothelial cell growth factor in prostatic adenocarcinoma.

T Sugamoto, N Tanji, S Nishio, M Yokoyama
Pages: 519-541
Published online on: 01 May 1999

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Article

Angiostatic activity of synthetic inhibitors of urokinase type plasminogen activator.

R Swiercz, E Skrzypczak-Jankun, M M Merrell, S H Selman, J Jankun
Pages: 523-529
Published online on: 01 May 1999

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Article

Clinicopathological significance of erbB-2 expression in colorectal carcinoma.

N L Chamberlain, R L Ward, N J Hawkins
Pages: 527-558
Published online on: 01 May 1999

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Article

Pleomorphic leiomyosarcoma of the soft parts: a reassessment by histology and immunohistochemistry of pleomorphic soft tissue sarcomas.

I Yamamoto, Y Oshiro, T Fukuda, M Tsuneyoshi
Pages: 533-540
Published online on: 01 May 1999

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Article

Expression of p53 and p21CIP1/WAF1 proteins in oral epithelial dysplasias and squamous cell carcinomas.

Y Kudo, T Takata, I Ogawa, S Sato, H Nikai
Pages: 539-584
Published online on: 01 May 1999

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Article

The usefulness of pharmacokinetic modulating chemotherapy (UFT plus 5FU) in the treatment of unresectable colorectal carcinomas.

M Kusunoki, H Yanagi, M Noda, T Yamamura
Pages: 547-599
Published online on: 01 May 1999

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Article

Inhibition of liver metastasis of colon cancer by in vivo administration of anti-vascular endothelial growth factor antibody.

K Okamoto, Y Oshika, Y Fukushima, M Yoshimura, Y Ohnishi, T Tokunaga, T Hashimoto, H Hatanaka, Y Tomii, Y Yoshida, S Miura, T Tsuchida, H Kijima, H Yamazaki, M Nakamura, Y Ueyama
Pages: 553-559
Published online on: 01 May 1999

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Article

Effects of interferon-alpha on cellular proliferation and adhesion of breast carcinoma cells.

M Maemura, Y Iino, J Horiguchi, H Takei, Y Horii, Y Koibuchi, T Yokoe, I Takeyoshi, S Ohwada, Y Morishita
Pages: 557-618
Published online on: 01 May 1999

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Article

Aphidicolin glycinate inhibits human neuroblastoma cell growth in vivo.

J Cinatl, R Kotchetkov, P H Driever, S Bertels, K Siems, G Jas, K Bindseil, H F Rabenau, P Pouckova, H W Doerr, D Schwabe
Pages: 563-571
Published online on: 01 May 1999

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Article

Expression of Mad1 protein inhibits proliferation of cancer cells and inversely correlated with Myc protein expression in primary gastric cancer.

S Han, K Park, H Y Kim, M S Lee, H J Kim, Y D Kim
Pages: 569-643
Published online on: 01 May 1999

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Article

Clinical significance of immunohistochemical Bcl-2 expression in invasive breast carcinoma.

H Takei, T Oyama, Y Iino, J Horiguchi, T Hikino, M Maemura, H Nagaoka, K Iijima, T Yokoe, T Nakajima, Y Morishita
Pages: 575-656
Published online on: 01 May 1999

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Article

The effects of nicotinamide plus carbogen or pions for microscopic SCCVII tumors.

A Nishioka, Y Ohizumi, G K Lam, T A Pickles, D J Chaplin, Y Ogawa, T Inomata, S Yoshida
Pages: 583-589
Published online on: 01 May 1999

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Article

Hepatic arterial infusion chemotherapy with continuous low dose administration of cisplatin and 5-fluorouracil for multiple recurrence of hepatocellular carcinoma after surgical treatment.

K Okuda, M Tanaka, J Shibata, E Ando, T Ogata, H Kinoshita, N Eriguchi, S Aoyagi, K Tanikawa
Pages: 587-678
Published online on: 01 May 1999

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Article

Enhancement of antitumor effect of hyperthermia with glucose administration in murine mammary carcinoma.

K Akagi, Y Aoki, R Nasu, K Nagata, Y Itagaki, S Sawada
Pages: 593-599
Published online on: 01 May 1999

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Article

Loss of heterozygosity of methylenetetrahydrofolate reductase in colon carcinomas.

P Pereira, V Stanton, S Jothy, I P Tomlinson, W D Foulkes, R Rozen
Pages: 597-606
Published online on: 01 May 1999

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Article

Diffuse bone metastasis with hematologic disorders from gastric cancer: clinicopathological features and prognosis.

T Etoh, H Baba, A Taketomi, H Nakashima, S Kohnoe, Y Seo, T Fukuda, H Tomoda
Pages: 601-606
Published online on: 01 May 1999

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Article

Association of hyaluronidase and breast adenocarcinoma invasiveness.

A K Madan, K Yu, N Dhurandhar, C Cullinane, Y Pang, D J Beech
Pages: 607-616
Published online on: 01 May 1999

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Article

Relationship of urokinase and urokinase receptor in non-small cell lung cancer to proliferation, angiogenesis, metastasis and patient survival.

M Volm, J Mattern, R Koomagi
Pages: 611-616
Published online on: 01 May 1999

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Article

Platelet-derived endothelial cell growth factor is not implicated in progression of cervical cancer.

J Kodama, N Seki, K Tokumo, A Hongo, Y Miyagi, M Yoshinouchi, H Okuda, T Kudo
Pages: 617-637
Published online on: 01 May 1999

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Article

Interferon gamma increases the antitumor activity of mitomycin C against human colon cancer cells in vitro and in vivo.

M Ishihara, T Kubota, M Watanabe, Y Kawano, S Narai, N Yasui, Y Otani, T Teramoto, M Kitajima
Pages: 621-626
Published online on: 01 May 1999

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Article

Growth inhibition of human osteosarcoma HuO9 cells by methylglyoxal bis(cyclopentylamidinohydrazone) in vitro and in vivo.

N Satoh, H Hibasami, K Mori, H Kaneko, H Wakabayashi, K Hirata, J Sonoda, K Nakashima, A Uchida
Pages: 627-657
Published online on: 01 May 1999

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Article

Combined pre-operative chemotherapy with intra-arterial cisplatin and continuous intravenous adriamycin for high grade osteosarcoma.

S Y Rha, H C Chung, S J Gong, K Y Shim, J B Ahn, W I Yang, K H Shin, N C Yoo, J H Kim, J K Roh, C I Lee, B S Kim
Pages: 631-638
Published online on: 01 May 1999

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Article

Expression of type I interferon receptor in renal cell carcinoma.

L Morell-Quadreny, B Fenollosa-Entrena, F Clar-Blanch, S Navarro-Fos, A Llombart-Bosch
Pages: 639-681
Published online on: 01 May 1999

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Article

Pilot study of combined treatment with continuous infusion of 5-fluorouracil, mitomycin C, and cisplatin (FMP) in patients with inoperable advanced gastric cancer.

W Koizumi, S Tanabe, M Kurihara, I Kondou, I Yamazaki, K Saigenji
Pages: 643-649
Published online on: 01 May 1999

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Article

Lack of gene amplification as a mechanism of CDK4 activation in human neuroblastoma.

X Fan, L Gómez, M Nistal, L Sierrasesúmaga, J S Castresana
Pages: 647-697
Published online on: 01 May 1999

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Article

Primary non-Hodgkin's lymphoma of the female genital tract.

M Amichetti, E Chiappe, S Mussari, L Busana, O Caffo, F Botto, E Galligioni, L Tomio
Pages: 651-655
Published online on: 01 May 1999

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Article

Loss of heterozygosity at the ATM locus in colorectal carcinoma.

N Uhrhammer, J Bay, D Pernin, P Rio, M Grancho, F Kwiatkowski, S Gosse-Brun, A Daver, Y Bignon
Pages: 655-663
Published online on: 01 May 1999

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Article

Technetium-99m methylene diphosphonate scintimammography for evaluation of palpable breast masses.

J K Lee, C H Kao, S S Sun
Pages: 659-722
Published online on: 01 May 1999

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Article

A malignancy work-up in patients with cancer-associated (paraneoplastic) autoimmune diseases: pemphigus and myasthenic syndromes as cases in point (review).

Y Sherer, Y Shoenfeld
Pages: 665-673
Published online on: 01 May 1999

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Article

CD80 and IL-2 signals cooperate in the regression of tumors transplanted in congenitally athymic mice.

V Sobota, M Indrová, P Rössner, J Bubeník, T Jandlová
Pages: 669-742
Published online on: 01 May 1999

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Article

Usefulness of p53 protein, Bcl-2 protein and Ki-67 as predictors of chemosensitivity of malignant tumors.

M Itaya, J Yoshimoto, K Kojima, S Futagawa
Pages: 675-757
Published online on: 01 May 1999

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Article

Efficacy of all-trans retinoic acid for molecular relapse of acute promyelocytic leukemia during remission.

S Tamura, Y Takemoto, S Takami, M Kinoshita, Y Kumano, H Aono, M Mori, E Kakishita
Pages: 683-688
Published online on: 01 May 1999

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Article

Prognostic value of p27Kip1 and p21WAF/Cip protein expression in muscle invasive bladder cancer.

M A Kuczyk, S Machtens, C Bokemeyer, K Hradil, I Macheel, V Jetscho, J Hartmann, W F Thon, U Jonas, J Serth
Pages: 687-780
Published online on: 01 May 1999

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Article

Clinical utility of chromosome 17 alpha satellite probe in distinguishing benign mesothelium from malignant cells: a pilot study using routinely fixed specimens.

R L Zimmerman, M Bibbo
Pages: 695-703
Published online on: 01 May 1999

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Article

Clinical and biological characteristics of breast cancers in post-menopausal women receiving hormone replacement therapy for menopause.

R J Salmon, Y Ansquer, B Asselain, O Languille, G Lesec, Y Remvikos
Pages: 699-1402
Published online on: 01 May 1999

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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Article Open Access

MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Article Open Access

Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Article Open Access

Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Review Open Access

Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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Retraction Open Access

[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Article Open Access

Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Article Open Access

Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Article Open Access

Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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