Remarkable suppressive effect of consecutive low-dose cisplatin therapy on advanced ovarian clear cell adenocarcinoma.

  • Authors:
    • N Umesaki
    • T Tanaka
    • N Kawamura
    • M Miyama
    • T Ichimura
    • S Ogita
  • View Affiliations

  • Published online on: September 1, 1999     https://doi.org/10.3892/or.6.5.1035
  • Pages: 1035-1042
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Abstract

Ovarian clear cell adenocarcinoma (OCCA) is known to be less responsive to cisplatin and most other anti-cancer drugs and to have a poorer prognosis than other ovarian cancers. We report a rare case of stage IIIc OCCA in a patient who has been treated postoperatively with cisplatin alone and continues to survive after 7.5 years. In this case, 25 mg/m2/day of cisplatin was administered for 5 consecutive days every 4 weeks. After remission, intermittent administration of cisplatin every 3 to 4 months was performed 8 times. This case suggests that induction and intermittent chemotherapy using consecutive low-dose cisplatin administration may be a useful treatment for OCCA.

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Sep-Oct 1999
Volume 6 Issue 5

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Umesaki N, Tanaka T, Kawamura N, Miyama M, Ichimura T and Ogita S: Remarkable suppressive effect of consecutive low-dose cisplatin therapy on advanced ovarian clear cell adenocarcinoma.. Oncol Rep 6: 1035-1042, 1999
APA
Umesaki, N., Tanaka, T., Kawamura, N., Miyama, M., Ichimura, T., & Ogita, S. (1999). Remarkable suppressive effect of consecutive low-dose cisplatin therapy on advanced ovarian clear cell adenocarcinoma.. Oncology Reports, 6, 1035-1042. https://doi.org/10.3892/or.6.5.1035
MLA
Umesaki, N., Tanaka, T., Kawamura, N., Miyama, M., Ichimura, T., Ogita, S."Remarkable suppressive effect of consecutive low-dose cisplatin therapy on advanced ovarian clear cell adenocarcinoma.". Oncology Reports 6.5 (1999): 1035-1042.
Chicago
Umesaki, N., Tanaka, T., Kawamura, N., Miyama, M., Ichimura, T., Ogita, S."Remarkable suppressive effect of consecutive low-dose cisplatin therapy on advanced ovarian clear cell adenocarcinoma.". Oncology Reports 6, no. 5 (1999): 1035-1042. https://doi.org/10.3892/or.6.5.1035