Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.

  • Authors:
    • J E Nelson
    • R E Harris
  • View Affiliations

  • Published online on: January 1, 2000     https://doi.org/10.3892/or.7.1.169
  • Pages: 169-239
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Abstract

We examined the association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs) in a case control study of 417 prostate cancer patients and 420 group-matched control subjects. Regular daily use of over the counter NSAIDs, ibuprofen or aspirin, was associated with a 66% reduction in prostate cancer risk (odds ratio = 0.34, 95% confidence interval = 0.23-0.58, p<0.01). The risk of prostate cancer was also significantly reduced in men who reported taking prescription NSAIDs (odds ratio = 0.35, 95% confidence interval = 0.15-0.84, p<0.05). These results suggest that NSAIDs may have value in the chemoprevention of prostate cancer.

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Jan-Feb 2000
Volume 7 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Nelson J and Nelson J: Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.. Oncol Rep 7: 169-239, 2000
APA
Nelson, J., & Nelson, J. (2000). Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.. Oncology Reports, 7, 169-239. https://doi.org/10.3892/or.7.1.169
MLA
Nelson, J., Harris, R."Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.". Oncology Reports 7.1 (2000): 169-239.
Chicago
Nelson, J., Harris, R."Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.". Oncology Reports 7, no. 1 (2000): 169-239. https://doi.org/10.3892/or.7.1.169