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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Jan-Feb 2000 Volume 7 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.

  • Authors:
    • M Volm
    • R Koomagi

  • View Affiliations / Copyright

    Affiliations: Department of Oncological Diagnostics and Therapy, German Cancer Research Center, D-69120 Heidelberg, Germany.
  • Pages: 95-103
    |
    Published online on: January 1, 2000
       https://doi.org/10.3892/or.7.1.95
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Abstract

This analysis attempted to ascertain whether combining the expression of c-Myc and caspase-3 can improve the available prognostic information for patients with non-small cell lung carcinomas. To this purpose, the expression of c-Myc and caspase-3 was determined in 128 cases of non-small cell lung carcinoma. The median survival time for patients with c-Myc-negative carcinomas was 89 weeks; it was only 43 weeks for patients with c-Myc-positive tumors (p=0.03). The estimated increased relative risk for patients with c-Myc-positive tumors was 1.6. The median survival time for patients with caspase-3-negative carcinomas was 41 weeks while patients with caspase-3-positive carcinomas survived for 79 weeks (p=0.06). The relative risk for patients with caspase-3-negative tumors was 1.5. A significant inverse relationship between the expression of c-Myc and caspase-3 was observed (p=0.04). To determine whether the combination of c-Myc and caspase-3 expression has a higher prognostic significance, patients were grouped based on their expressions of both variables. Patients with c-Myc-negative and caspase-3-positive tumors had the most favorable prognosis (102 weeks) while c-Myc-positive and caspase-3-negative carcinomas had the most unfavorable prognosis (22 weeks; p=0.01).

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Copy and paste a formatted citation
Spandidos Publications style
Volm M and Koomagi R: Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.. Oncol Rep 7: 95-103, 2000.
APA
Volm, M., & Koomagi, R. (2000). Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.. Oncology Reports, 7, 95-103. https://doi.org/10.3892/or.7.1.95
MLA
Volm, M., Koomagi, R."Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.". Oncology Reports 7.1 (2000): 95-103.
Chicago
Volm, M., Koomagi, R."Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.". Oncology Reports 7, no. 1 (2000): 95-103. https://doi.org/10.3892/or.7.1.95
Copy and paste a formatted citation
x
Spandidos Publications style
Volm M and Koomagi R: Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.. Oncol Rep 7: 95-103, 2000.
APA
Volm, M., & Koomagi, R. (2000). Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.. Oncology Reports, 7, 95-103. https://doi.org/10.3892/or.7.1.95
MLA
Volm, M., Koomagi, R."Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.". Oncology Reports 7.1 (2000): 95-103.
Chicago
Volm, M., Koomagi, R."Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.". Oncology Reports 7, no. 1 (2000): 95-103. https://doi.org/10.3892/or.7.1.95
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