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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Mar-Apr 2000 Volume 7 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.

  • Authors:
    • M Orditura
    • F De Vita
    • A Belli
    • F Ciaramella
    • M Musicò
    • A Ferrigno
    • R Formato
    • G Abbate
    • M R Diadema
    • G Catalano

  • View Affiliations / Copyright

    Affiliations: Medical Oncology, Department of Clinical and Experimental Medicine <F. Magrassi>, Second University of Naples School of Medicine, C/o II Policlinico, I-80131 Naples, Italy.
  • Pages: 397-797
    |
    Published online on: March 1, 2000
       https://doi.org/10.3892/or.7.2.397
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Abstract

The aim of this study was to assess the protective effect and the safety profile of amifostine in 16 esophageal cancer patients undergoing neoadjuvant chemo-radiation therapy (group A) compared to 21 matched patients (group B), treated with the same schedule without receiving amifostine, and considered as controls. Haematological and extra-haematological toxicity were evaluated according to WHO criteria and considered as result of amifostine activity. The bone marrow toxicity was globally lower in group A than in group B. We recorded 4 cases of mucosities in group B compared to 1 case in group A. amifostine-related side effects were few (2 cases of hypotension and 1 of vomiting), mild, and well controlled. In conclusion, amifostine seems to be effective and safe when used as protective agent also in esophageal cancer.

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Copy and paste a formatted citation
Spandidos Publications style
Orditura M, De Vita F, Belli A, Ciaramella F, Musicò M, Ferrigno A, Formato R, Abbate G, Diadema M, Catalano G, Catalano G, et al: Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.. Oncol Rep 7: 397-797, 2000.
APA
Orditura, M., De Vita, F., Belli, A., Ciaramella, F., Musicò, M., Ferrigno, A. ... Catalano, G. (2000). Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.. Oncology Reports, 7, 397-797. https://doi.org/10.3892/or.7.2.397
MLA
Orditura, M., De Vita, F., Belli, A., Ciaramella, F., Musicò, M., Ferrigno, A., Formato, R., Abbate, G., Diadema, M., Catalano, G."Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.". Oncology Reports 7.2 (2000): 397-797.
Chicago
Orditura, M., De Vita, F., Belli, A., Ciaramella, F., Musicò, M., Ferrigno, A., Formato, R., Abbate, G., Diadema, M., Catalano, G."Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.". Oncology Reports 7, no. 2 (2000): 397-797. https://doi.org/10.3892/or.7.2.397
Copy and paste a formatted citation
x
Spandidos Publications style
Orditura M, De Vita F, Belli A, Ciaramella F, Musicò M, Ferrigno A, Formato R, Abbate G, Diadema M, Catalano G, Catalano G, et al: Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.. Oncol Rep 7: 397-797, 2000.
APA
Orditura, M., De Vita, F., Belli, A., Ciaramella, F., Musicò, M., Ferrigno, A. ... Catalano, G. (2000). Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.. Oncology Reports, 7, 397-797. https://doi.org/10.3892/or.7.2.397
MLA
Orditura, M., De Vita, F., Belli, A., Ciaramella, F., Musicò, M., Ferrigno, A., Formato, R., Abbate, G., Diadema, M., Catalano, G."Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.". Oncology Reports 7.2 (2000): 397-797.
Chicago
Orditura, M., De Vita, F., Belli, A., Ciaramella, F., Musicò, M., Ferrigno, A., Formato, R., Abbate, G., Diadema, M., Catalano, G."Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.". Oncology Reports 7, no. 2 (2000): 397-797. https://doi.org/10.3892/or.7.2.397
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