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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Mar-Apr 2000 Volume 7 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Differential effects of retinoids on nitric oxide production by promonocytic U937 cells and ZR-75-1 human breast cancer cells.

J H Martin, O Alalami, F Yaqoob
Pages: 219-242
Published online on: 01 March 2000

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Article

A novel monoclonal antibody, H9, directed against the core protein of MUC1 mucin.

H Hamada, N Kohno, A Yokoyama, K Kondo, S Z Yang, K Hiwada, K Watanabe, M Miyake
Pages: 225-257
Published online on: 01 March 2000

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Article

pS2 expression as a possible diagnostic marker of colorectal carcinoma in ulcerative colitis.

Y Hirota, S Tanaka, K Haruma, M Yoshihara, K Sumii, G Kajiyama, F Shimamoto, N Kohno
Pages: 233-242
Published online on: 01 March 2000

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Article

A favorable impact of preoperative FPLC chemotherapy on patients with gastric cardia cancer.

X L Wang, G X Wu, M D Zhang, M Guo, H Zhang, X F Sun
Pages: 241-245
Published online on: 01 March 2000

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Article

Is a woman's date of birth related to her risk of developing breast cancer?

S Kristoffersen, F Hartveit
Pages: 245-252
Published online on: 01 March 2000

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Article

A simultaneous monitoring of Lens culinaris agglutinin A-reactive alpha-fetoprotein and des-gamma-carboxy prothrombin as an early diagnosis of hepatocellular carcinoma in the follow-up of cirrhotic patients.

Y Shimauchi, M Tanaka, R Kuromatsu, R Ogata, Y Tateishi, S Itano, N Ono, S Yutani, H Nagamatsu, S Matsugaki, S Yamasaki, K Tanikawa, M Sata
Pages: 249-305
Published online on: 01 March 2000

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Article

In vivo chemosensitivity of human malignant cystosarcoma phyllodes xenografts.

Y Ueyama, Y Abe, Y Ohnishi, N Sawa, H Hatanaka, A Handa, Y Tokuda, H Yamazaki, H Kijima, N Tamaoki, M Nakamura
Pages: 257-317
Published online on: 01 March 2000

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Article

Induction of p53-dependent apoptosis in vivo by nedaplatin and ionizing radiation.

Y Nakamura, M Hasegawa, K Hayakawa, M Matsuura, Y Suzuki, S Nasu, M Yamakawa, N Mitsuhashi, H Niibe
Pages: 261-266
Published online on: 01 March 2000

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Article

Comparison of effects of doxorubicin and radiation on p53-dependent apoptosis in vivo.

K Hayakawa, M Hasegawa, M Kawashima, Y Nakamura, M Matsuura, H Toda, N Mitsuhashi, H Niibe
Pages: 267-337
Published online on: 01 March 2000

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Article

Perioperative quantitative analysis of cytokeratin 20 mRNA in peripheral venous blood of patients with colorectal adenocarcinoma.

N O Funaki, J Tanaka, T Sugiyama, G Ohshio, A Nonaka, F Yotsumoto, M Furutani, M Imamura
Pages: 271-277
Published online on: 01 March 2000

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Article

Expression of estrogen and progesterone receptors in carcinomas of the female breast in Tanzania.

M P Mbonde, H Amir, R Schwartz-Albiez, L A Akslen, J N Kitinya
Pages: 277-360
Published online on: 01 March 2000

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Article

Bcl-2 related proteins are dramatically induced at the early stage of differentiation in human liver cancer cells by a histone deacetylase inhibitor projecting an anti-apoptotic role during this period.

K Wakabayashi, H Saito, H Ebinuma, Y Saito, T Takagi, M Nakamura, A Umezawa, J Hata, H Ishii
Pages: 285-293
Published online on: 01 March 2000

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Article

Experimental study of the effects on apoptosis of docetaxel alone and in combination with irradiation.

M Matsuura, M Hasegawa, K Hayakawa, M Kawashima, S Nasu, Y Nakamura, N Mitsuhashi, H Niibe
Pages: 289-382
Published online on: 01 March 2000

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Article

Immunohistochemical study on primary and recurrent tumors in patients with local recurrence in the conserved breast.

J Horiguchi, Y Iino, H Takei, M Maemura, Y Koibuchi, I Takeyoshi, S Ohwada, T Yokoe, T Nakajima, T Oyama, Y Morishita
Pages: 295-303
Published online on: 01 March 2000

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Article

DNA double-strand break rejoining in human follicular lymphoma and glioblastoma tumor cells.

A M Macann, R A Britten, S Poppema, R Pearcey, E Rosenberg, M J Allalunis-Turner, D Murray
Pages: 299-602
Published online on: 01 March 2000

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Article

Dose-intensive weekly alternating chemotherapy for patients with small cell lung cancer: randomized trial, can it improve survival of patients with good prognostic factors?

M Masutani, Y Ochi, A Kadota, H Akusawa, A Kisohara, N Takahashi, Y Koya, T Horie
Pages: 305-315
Published online on: 01 March 2000

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Article

Retrospective study of the prognostic factors of remission induction for single-agent chemotherapy with cisplatin in advanced epithelial ovarian cancer.

Y Matsumoto, M Deguchi, O Ishiko, S Ogita
Pages: 311-314
Published online on: 01 March 2000

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Article

Genomic DNA analyses of spontaneous hepatocellular carcinomas in LEC rat liver using a new technique.

H Nagai, T Sugiyama, H Yoshikawa, Y S Kim, S Y Yeo, N Konishi, K Matsubara
Pages: 315-323
Published online on: 01 March 2000

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Article

Prognostic comparison between peripheral and central types of squamous cell carcinoma of the lung in patients undergoing surgical resection.

Y Mizushima, R Yamashita, Y Kusajima, S Sugiyama
Pages: 319-341
Published online on: 01 March 2000

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Article

Mutational analysis of the CTNNB1 (beta-catenin) gene in human endometrial cancer: frequent mutations at codon 34 that cause nuclear accumulation.

T Ikeda, K Yoshinaga, S Semba, E Kondo, H Ohmori, A Horii
Pages: 323-329
Published online on: 01 March 2000

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Article

Exploratory study of effective chemotherapy to clear cell carcinoma of the ovary.

T Kita, Y Kikuchi, K Kudoh, M Takano, T Goto, J Hirata, T Tode, I Nagata
Pages: 327-358
Published online on: 01 March 2000

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Article

Clinical significance of serum vascular endothelial growth factor in colorectal cancer patients: correlation with clinicopathological factors and tumor markers.

A Takeda, H Shimada, H Imaseki, S Okazumi, T Natsume, T Suzuki, T Ochiai
Pages: 333-341
Published online on: 01 March 2000

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Article

Neoadjuvant chemotherapy for osteosarcoma of the extremities with synchronous lung metastases: treatment with cisplatin, adriamycin and high dose of methotrexate and ifosfamide.

G Bacci, A Briccoli, S Ferrari, G Saeter, D Donati, A Longhi, M Manfrini, F Bertoni, S Rimondini, C Monti, C Forni
Pages: 339-385
Published online on: 01 March 2000

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Article

Antiproliferative action of melatonin on human prostate cancer LNCaP cells.

R M Moretti, M M Marelli, R Maggi, D Dondi, M Motta, P Limonta
Pages: 347-398
Published online on: 01 March 2000

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Article

Correlation of immunohistochemical staining and mutations of p53 in human hepatocellular carcinoma.

C C Hsia, Y Nakashima, S S Thorgeirsson, C C Harris, M Minemura, S Momosaki, N J Wang, E Tabor
Pages: 353-359
Published online on: 01 March 2000

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Article

Serum interleukin-10 is an independent prognostic factor in advanced solid tumors.

F De Vita, M Orditura, G Galizia, C Romano, E Lieto, P Iodice, C Tuccillo, G Catalano
Pages: 357-418
Published online on: 01 March 2000

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Article

Bovine seminal ribonuclease inhibits in vivo growth of human neuroblastoma cells.

R Kotchetkov, J Cinatl, J Matousek, J Vogel, P Pouckova, M Wagner, B Kornhuber, D Schwabe
Pages: 363-370
Published online on: 01 March 2000

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Article

Frequent genotype changes at -308 of the human tumor necrosis factor-alpha promoter region in human uterine endometrial cancer.

M Sasaki, K Nakajima, G Perinchery, T Fujino, B R Oh, S Fujimoto, R Dahiya
Pages: 369-442
Published online on: 01 March 2000

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Article

The effect of external beam irradiation after endoscopic palliation of esophageal carcinoma.

A Maier, U Anegg, R Lunzer, U Prettenhofer, P Rehak, O Sankin, B Fell, H Pinter, F M Smolle-Juttner
Pages: 375-384
Published online on: 01 March 2000

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Article

p53 inactivating mutations in chinese breast carcinomas.

Z Y Gong, K W Wong, Y Li, Y R Mao, M L Lung
Pages: 381-386
Published online on: 01 March 2000

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Article

Susceptibility to the induction of glutathione S-transferase positive hepatic foci in offspring rats after gamma-ray exposure during gestation.

Y S Lee, M J Lee, M Lee, J Jang
Pages: 387-477
Published online on: 01 March 2000

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Article

High fat diet elevates the activity of inducible nitric oxide synthase and 1,2-dimethylhydrazine-induced aberrant crypt foci in colon of rats.

G Wan, N Kato, H Watanabe
Pages: 391-396
Published online on: 01 March 2000

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Article

Efficacy and safety profile of amifostine in the preoperative combined therapy of esophageal cancer patients.

M Orditura, F De Vita, A Belli, F Ciaramella, M Musicò, A Ferrigno, R Formato, G Abbate, M R Diadema, G Catalano
Pages: 397-797
Published online on: 01 March 2000

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Article

Cytogenetic and molecular abnormalities in astrocytic gliomas (Review).

A C Goussia, N J Agnantis, J S Rao, A P Kyritsis
Pages: 401-413
Published online on: 01 March 2000

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Article

Giant cell tumor of tendon sheath, tenosynovial giant cell tumor, and pigmented villonodular synovitis: defining the presentation, surgical therapy and recurrence.

R C Martin, D L Osborne, M J Edwards, W Wrightson, K M McMasters
Pages: 413-422
Published online on: 01 March 2000

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Article

Alterations in the retinoblastoma pathway of cell cycle control in parathyroid tumors.

I Szijan, I Orlow, V Dalamon, P Vergani, K Danilowicz, N Mezzadri, C Cordon-Cardo, O D Bruno
Pages: 421-426
Published online on: 01 March 2000

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Article

Allelic imbalance at NBS1 is frequent in both proximal and distal colorectal carcinoma.

N Uhrhammer, J O Bay, S Gosse-Brun, F Kwiatkowski, P Rio, A Daver, Y J Bignon
Pages: 427-458
Published online on: 01 March 2000

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Article

High-resolution DNA flow cytometry in oral verrucous carcinoma.

J Hemmer, K Kraft
Pages: 433-438
Published online on: 01 March 2000

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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