High-resolution DNA flow cytometry in oral verrucous carcinoma.

  • Authors:
    • J Hemmer
    • K Kraft
  • View Affiliations

  • Published online on: March 1, 2000     https://doi.org/10.3892/or.7.2.433
  • Pages: 433-438
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Abstract

The classification of verrucous carcinoma as an entity unto itself or as a variant of well differentiated squamous cell carcinoma is controversial. To contribute new insights into the biological behavior of this rare tumor, we applied DNA flow cytometry to three node-negative verrucous carcinomas of the oral cavity. All tumors expressed a single aneuploid cell population. One of the patients experienced three courses with local recurrence. All secondary tumors retained the initially established aneuploid clone. The development of aneuploidy is thus a cytogenetic event common to both verrucous and squamous carcinoma of the oral cavity.

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Mar-Apr 2000
Volume 7 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Hemmer J and Hemmer J: High-resolution DNA flow cytometry in oral verrucous carcinoma.. Oncol Rep 7: 433-438, 2000
APA
Hemmer, J., & Hemmer, J. (2000). High-resolution DNA flow cytometry in oral verrucous carcinoma.. Oncology Reports, 7, 433-438. https://doi.org/10.3892/or.7.2.433
MLA
Hemmer, J., Kraft, K."High-resolution DNA flow cytometry in oral verrucous carcinoma.". Oncology Reports 7.2 (2000): 433-438.
Chicago
Hemmer, J., Kraft, K."High-resolution DNA flow cytometry in oral verrucous carcinoma.". Oncology Reports 7, no. 2 (2000): 433-438. https://doi.org/10.3892/or.7.2.433