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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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May-June 2001 Volume 8 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May-June 2001 Volume 8 Issue 3

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Article

Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia

  • Authors:
    • Nathalie Henriques Silva
    • Glicinia Pimenta
    • Wolmar Alcantara Pulcheri
    • Marcia Vasconcellos Fournier
    • Nelson Spector
    • M. G. da Costa Carvalho

  • View Affiliations / Copyright

    Affiliations: Laboratorio de Controle da Expressao Genica, Instituto de Biofisica Carlos Chagas Filho, UFRJ, Centro de Ciencias da Saude (CCS), Ilha do Fundao, Rio de Janeiro, RJ, CEP 21949-900, Brazil
  • Pages: 693-696
    |
    Published online on: May 1, 2001
       https://doi.org/10.3892/or.8.3.693
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Abstract

We investigated the presence of free mRNA in the plasma of patients with chronic myeloid leukemia (CML), through RT-PCR analysis of G3PDH, a metabolism gene. We also analysed the presence of mRNA for HLM, a human oxysterol-binding protein homologue recently described as a potential marker for blood dissemination of solid tumors. Our results showed the presence of metabolism G3PDH mRNA in the plasma of 5/11 (45%) CML patients studied but HLM mRNA was not detected in any of the plasma studied. HLM mRNA was detected in the leukocytes of 4/5 (80%) CML patients. This work reports for the first time free mRNA in the plasma of CML patients. Our results also suggest that the detection of HLM could be a potential molecular marker for the follow-up in hematological malignancies.

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Copy and paste a formatted citation
Spandidos Publications style
Silva NH, Pimenta G, Pulcheri WA, Fournier MV, Spector N and da Costa Carvalho MG: Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia. Oncol Rep 8: 693-696, 2001.
APA
Silva, N.H., Pimenta, G., Pulcheri, W.A., Fournier, M.V., Spector, N., & da Costa Carvalho, M.G. (2001). Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia. Oncology Reports, 8, 693-696. https://doi.org/10.3892/or.8.3.693
MLA
Silva, N. H., Pimenta, G., Pulcheri, W. A., Fournier, M. V., Spector, N., da Costa Carvalho, M. G."Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia". Oncology Reports 8.3 (2001): 693-696.
Chicago
Silva, N. H., Pimenta, G., Pulcheri, W. A., Fournier, M. V., Spector, N., da Costa Carvalho, M. G."Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia". Oncology Reports 8, no. 3 (2001): 693-696. https://doi.org/10.3892/or.8.3.693
Copy and paste a formatted citation
x
Spandidos Publications style
Silva NH, Pimenta G, Pulcheri WA, Fournier MV, Spector N and da Costa Carvalho MG: Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia. Oncol Rep 8: 693-696, 2001.
APA
Silva, N.H., Pimenta, G., Pulcheri, W.A., Fournier, M.V., Spector, N., & da Costa Carvalho, M.G. (2001). Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia. Oncology Reports, 8, 693-696. https://doi.org/10.3892/or.8.3.693
MLA
Silva, N. H., Pimenta, G., Pulcheri, W. A., Fournier, M. V., Spector, N., da Costa Carvalho, M. G."Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia". Oncology Reports 8.3 (2001): 693-696.
Chicago
Silva, N. H., Pimenta, G., Pulcheri, W. A., Fournier, M. V., Spector, N., da Costa Carvalho, M. G."Detection of messenger RNA in leukocytes or plasma of patients with chronic myeloid leukemia". Oncology Reports 8, no. 3 (2001): 693-696. https://doi.org/10.3892/or.8.3.693
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