Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases

  • Authors:
    • Masaya mukai
    • H. Moriya
    • S. Himeno
    • Y. Oida
    • S. mukohyama
    • Takayuki Nishi
    • H. Nakasaki
    • S. Satoh
    • H. Makuuchi
  • View Affiliations

  • Published online on: September 1, 2001     https://doi.org/10.3892/or.8.5.1079
  • Pages: 1079-1083
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Abstract

Case 1: a patient was diagnosed as having ascending colon cancer with right ovarian metastasis, and underwent palliative right hemicolectomy plus oophorectomy. The tumor was a well-differentiated adenocarcinoma with right ovarian metastasis, and the disease was classified as stage IV. Oral chemotherapy with UFT plus LV was performed for about 3 years, and the patient is still being followed up with no recurrence at 5 years postoperatively. Case 2: a patient was diagnosed as having incomplete large bowel obstruction caused by ascending colon cancer, and underwent curative right hemicolectomy. The tumor was a moderately differentiated adenocarcinoma, and the disease was classified as stage II. Since multiple liver metastases developed at 3 months postoperatively, oral chemotherapy with UFT plus LV was started. Imaging studies showed the complete elimination of liver metastases after 2 months. Subsequently, liver metastasis recurred about 10 months later. The patient died of unrelated cerebral infarction at 2 years and 6 months postoperatively.

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September-October 2001
Volume 8 Issue 5

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
mukai M, Moriya H, Himeno S, Oida Y, mukohyama S, Nishi T, Nakasaki H, Satoh S and Makuuchi H: Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases. Oncol Rep 8: 1079-1083, 2001
APA
mukai, M., Moriya, H., Himeno, S., Oida, Y., mukohyama, S., Nishi, T. ... Makuuchi, H. (2001). Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases. Oncology Reports, 8, 1079-1083. https://doi.org/10.3892/or.8.5.1079
MLA
mukai, M., Moriya, H., Himeno, S., Oida, Y., mukohyama, S., Nishi, T., Nakasaki, H., Satoh, S., Makuuchi, H."Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases". Oncology Reports 8.5 (2001): 1079-1083.
Chicago
mukai, M., Moriya, H., Himeno, S., Oida, Y., mukohyama, S., Nishi, T., Nakasaki, H., Satoh, S., Makuuchi, H."Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases". Oncology Reports 8, no. 5 (2001): 1079-1083. https://doi.org/10.3892/or.8.5.1079