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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-October 2001 Volume 8 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Adenoviral-mediated gene therapy of human bladder cancer with antisense interleukin-8

Keiji Inoue, Christopher G. Wood, Joel W. Slaton, Takashi Karashima, Paul Sweeney, Colin P.N. Dinney
Pages: 955-964
Published online on: 01 September 2001

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Article

Expression of DNA mismatch repair proteins hMSH2 and hMLH1 and the cyclin G1 inhibitor, p21(waf1/cip1) in pediatric tumors: Correlation with response to therapy

H. A. Idikio
Pages: 965-971
Published online on: 01 September 2001

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Article

Combined evaluation of NGF and p75NGFR expression is a biomarker for predicting prognosis in human invasive ductal breast carcinoma

Yuichiro Sakamoto, Yoshihiko Kitajima, Genichiro Edakuni, Takahiro Hamamoto, Kohji Miyazaki
Pages: 973-980
Published online on: 01 September 2001

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Article

Carbohydrate antigens as a risk factor for hematogenous recurrence of esophageal squamous cell carcinoma patients

Tomokazu Makino, Yutaka Shimada, Masato Maeda, Izumi Komoto, Masayuki Imamura
Pages: 981-985
Published online on: 01 September 2001

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Article

The influence of hormones on CD44 expression in endometrial and breast carcinomas

Bettina Durst, Rudiger V. Sorg, Gernot Roder, Beate Betz, Matthias W. Beckmann, Dieter Niederacher, Hans G. Bender, Peter Dall
Pages: 987-993
Published online on: 01 September 2001

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Article

Detection of Epstein-Barr virus in gastrectomy specimens

Yunus A. Luqmani, Sultan O. Linjawi, Sami Shousha
Pages: 995-999
Published online on: 01 September 2001

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Article

Genomic instability and breast cancer

S. Colleu-Durel, N. Guitton, K. Nourgalieva, J. Leveque, B. Danic, C. chenal
Pages: 1001-1005
Published online on: 01 September 2001

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Article

Radiosensitization in sarcoma cell lines with a p53 missense mutation correlates with prevention of irradiation G2/M arrest but not with induction of apoptosis

M. Bache, S. Oehlmann, A. Meye, F. Bartel, M. Kappler, P. Wurl, H. Schmidt, F.-W. Rath, J. Dunst, H. Taubert
Pages: 1007-1011
Published online on: 01 September 2001

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Article

Pharmaco-economic study of intensive chemotherapy with peripheral blood progenitor cell support for advanced breast cancer

Frederic Pinguet, Karine Savelli, Isabelle Petit, Yasmina Gerbi-Benmansour, Michel Fabbro
Pages: 1013-1017
Published online on: 01 September 2001

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Article

Bcl-2 expression in breast cancer is down-regulated by trans-arterial administration of chemotherapeutic agents

T. Sato, H. Kijima, A. Suto, S. Sato, H. Yoshida, Y. Terasaki-Fukuzawa, M. Shimbori, N. Onoda, R. Y. Osamura, T. Takeshita
Pages: 1019-1022
Published online on: 01 September 2001

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Article

Cyclooxygenase-2 expression in an adenoid cystic carcinoma of the uterine cervix

O. Ishiko, T. Sumi, H. Yoshida, O. Tokuyama, K. Wakasa, T. Haba, S. Ogita
Pages: 1023-1025
Published online on: 01 September 2001

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Article

Sudden termination of G-CSF injection leads to apoptosis of a large proportion of increased granulocytes

Y. Ogawa, T. Kobayashi, A. Nishioka, S. Kariya, E. Garcia del Saz, H. Seguchi, S. Yoshida
Pages: 1027-1029
Published online on: 01 September 2001

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Article

Conservative management of placental polyp with oral administration of methotrexate

Seiichi Yamamasu, Yuichiro Nakai, Junko Nishio, Y. Hyun, K.-I. Honda, K. Hirai, O. Ishiko, S. Ogita
Pages: 1031-1033
Published online on: 01 September 2001

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Article

Stilbene estrogen produces higher levels of mitochondrial DNA adducts than nuclear DNA adducts in the target organ of cancer (liver) of male Sprague Dawley rats

Ronald D. Thomas, Deodutta Roy
Pages: 1035-1038
Published online on: 01 September 2001

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Article

Molecular analysis of CDKN2 (p16) in gliomas associated with clinical data

Patricia De Souza Nascimento, Carla Mendes Maciel, Marcia Tie Kawamura, Jose Antonio Oliveira, Anselmo Teixeira, Maria da Gloria Costa Carvalho, Gilda Alves
Pages: 1039-1043
Published online on: 01 September 2001

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Article

Transplacental effect of a 15% olive-oil diet on functional activity of immune components in the spleen and colon tumors of rat offspring

G. Kossoy, Z. Madar, H. Ben-Hur, R. Gal, A. Stark, O. Cohen, I. Zusman
Pages: 1045-1049
Published online on: 01 September 2001

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Article

Relationship between existence of lymphatic invasion in peritumoral breast tissue and presence of axillary lymph node metastasis in invasive ductal carcinoma of the breast

M. Kurosumi, K. Suemasu, T. Tabei, K. Inoue, H. Matsumoto, N. Sugamata, Y. Higashi
Pages: 1051-1055
Published online on: 01 September 2001

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Article

Human colon cancer produces a factor which induces the proliferation of venous endothelial cells

Kazuomi Iwasaki, Masayuki Yamamoto, Shigeki Minami, Ko Komuta, Junzo Yamaguchi, Junichiro Furui, Takashi Kanematsu
Pages: 1057-1061
Published online on: 01 September 2001

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Article

Cdc6 expression as a marker of proliferative activity in brain tumors

Seiji Ohta, Masayo Koide, Tsutomu Tokuyama, Naoki Yokota, Shigeru Nishizawa, Hiroki Namba
Pages: 1063-1066
Published online on: 01 September 2001

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Article

A randomized study comparing oral and standard regimens for metastatic breast cancer

Taisuke Hori, Hiroshi Kodama, Satoru Nishimura, Takehiko Hatano, Ryuji Okamura, Koji Fujii, Takashi Kudo, Takashi Inamoto, Kiyoshi Sawai, Masao Kobayashi, Hiroki Ogawa, Norio Yoshimura, Masahiro Hiraoka
Pages: 1067-1071
Published online on: 01 September 2001

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Article

The tumor-preventing effect of a mixture of several lactic acid bacteria on 1,2-dimethylhydrazine-induced colon carcinogenesis in mice

Masaru Fukui, Takehiko Fujino, Koichiro Tsutsui, Toru Maruyama, Hiroko Yoshimura, Takako Shinohara, Masakazu Fukui, Osami Nada
Pages: 1073-1078
Published online on: 01 September 2001

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Article

Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases

Masaya mukai, H. Moriya, S. Himeno, Y. Oida, S. mukohyama, Takayuki Nishi, H. Nakasaki, S. Satoh, H. Makuuchi
Pages: 1079-1083
Published online on: 01 September 2001

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Article

DNA methylation status of hMLH1, p16INK4a, and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas

N. Oue, K. Kuraoka, H. Kuniyasu, H. Yokozaki, A. Wakikawa, K. Matsusaki, W. Yasui
Pages: 1085-1089
Published online on: 01 September 2001

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Article

Doenjang hexane fraction-induced G1 arrest is associated with the inhibition of pRB phosphorylation and induction of Cdk inhibitor p21 in human breast carcinoma MCF-7 cells

Y. H. Choi, B. T. Choi, W. H. Lee, S.-H. Rhee, K. Y. Park
Pages: 1091-1096
Published online on: 01 September 2001

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Article

Plasma VEGF concentration can predict the tumor angiogenic capacity in non-small cell lung cancer

Masaya Tamura, Yasuhiko Ohta, Takeshi Kajita, Keiichi Kimura, Tetsuhiko Go, Makoto Oda, Hisoyuhi Nakamura, Goh Watanabe
Pages: 1097-1102
Published online on: 01 September 2001

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Article

Preoperative therapy with insufficient effectiveness is related to unfavorable prognosis of patients with esophageal squamous cell carcinoma

T. Nozoe, H. Saeki, T. Ohga, K. Sugimachi
Pages: 1103-1106
Published online on: 01 September 2001

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Article

Prognostic value of plasma transforming growth factor-β in patients with glioblastoma multiforme

M.C. C.M. Hulshof, P. Sminia, A. D. Barten-van Rijbroek, D. Gonzalez Gonzalez
Pages: 1107-1110
Published online on: 01 September 2001

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Article

Gemcitabine plus epirubicin in advanced pancreatic cancer: A phase II multicenter trial

Giovanni Pietro Ianniello, Michele Orditura, Antonio Rossi, Ferdinando De Vita, Luigi Maiorino, Francesco Carrozza, Luigi Manzione, Giuseppe Catalano
Pages: 1111-1115
Published online on: 01 September 2001

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Article

Muscle wasting after radiotherapy in young and adult rats

C. C.M. Persons, A. F. Hermens, N. A.P. Franken, J. Wondergem
Pages: 1117-1122
Published online on: 01 September 2001

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Article

Expression of tumor-associated glycoprotein-72 (TAG-72) antigen in human prostatic adenocarcinomas

Dev Karan, Sonny L. Johansson, Ming-Fong Lin, Surinder K. Batra
Pages: 1123-1126
Published online on: 01 September 2001

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Article

Expression of the c-erb-B2 and p53 protein in gallbladder carcinomas

Youn Wha Kim, Se Ho Huh, Yong-Koo Park, Tae Young Yoon, Sang Mok Lee, Sung Hwa Hong
Pages: 1127-1132
Published online on: 01 September 2001

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Article

Loss of heterozygosity of nucleotide excision repair factors in sporadic oral squamous cell carcinoma using microdissected tissue

Hitoshi Miyashita, Shiro Mori, Naoko Tanda, Kentaro Nakayama, Atsuko Kanzaki, Atushi Sato, Hidehiro Morikawa, Katutoshi Motegi, Yuji Takebayashi, Manabu Fukumoto
Pages: 1133-1138
Published online on: 01 September 2001

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Article

Cytomorphologic features characteristic of tumor stages of thymomas

Masayuki Baba, Yasushi Nomoto, Akira Iyoda, Hiroko Saito, Kenzo Hiroshima, Kiyoshi Shibuya, Yukiko Haga, Hidehisa Hoshino, Toshihiko Iizasa, Fumio Horiuchi, Takehiko Fujisawa
Pages: 1139-1143
Published online on: 01 September 2001

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Article

The role of 18F-fluorodeoxyglucose positron emission tomography in cancer screening - A preliminary report

C.-H. Kao, A. S. Kwan, J. K. Kwan, M.-J. Chow
Pages: 1145-1148
Published online on: 01 September 2001

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Article

An intranodal morcellation technique employing loop electrosurgical excision procedure for large prolapsed pedunculated myomas

Y. Kanaoka, K. Hirai, O. Ishiko, S. Ogita
Pages: 1149-1151
Published online on: 01 September 2001

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Article

Role of iron in lymphoma-induction by ATP

Leopold J. Anghileri, Francois Plenat, Pierre Thouvenot
Pages: 1153-1157
Published online on: 01 September 2001

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Article

Expressions of c-erbB-2, epidermal growth factor receptor and pan-ras proto-oncogenes in adenocarcinoma of the cervix: Correlation with clinical prognosis

Tsin-Wah Leung, Annie N.Y. Cheung, Danny K.L. Cheng, Ling-Chui Wong, Hextan Y.S. Ngan
Pages: 1159-1164
Published online on: 01 September 2001

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Article

Immune reactivity during the growth of a murine lung adenocarcinoma: Evaluation of paraneoplastic syndrome development

Miriam J. Diament, Corina Garcia, Mariano Parma, Nelida Mondelo, Isabel Stillitani, Slobodanka Klein
Pages: 1165-1170
Published online on: 01 September 2001

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Article

Pharmacokinetic and biochemical analysis in the treatment of weekly paclitaxel in relapsed breast cancer

Ryungsa Kim, Akihiko Osaki, Tetsuya Toge
Pages: 1171-1176
Published online on: 01 September 2001

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Article

Immunohistochemical study of Muc1, Muc2 and human gastric mucin in breast carcinoma: Relationship with prognostic factors

Youqing Xu, Noriko Kimura, Ryuichi Yoshida, Hitoshi Lin, Kaoru Yoshinaga
Pages: 1177-1182
Published online on: 01 September 2001

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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