Livistona extract inhibits angiogenesis and cancer growth

  • Authors:
    • Maryam R. Sartippour
    • Canhui Liu
    • Zhi-Ming Shao
    • Vay Liang Go
    • David Heber
    • Mai Nguyen
  • View Affiliations

  • Published online on: November 1, 2001     https://doi.org/10.3892/or.8.6.1355
  • Pages: 1355-1357
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Abstract

In a screen for naturally occurring angiogenic inhibitors, we have identified an extract from the seed of the plant Livistona chinensis, which has potent anti-angiogenic and anti-tumor activity. The aqueous extract inhibits the in vitro proliferation of endothelial cells and multiple tumor cell lines including mouse fibrosarcoma and human breast and colon cancer. In mouse experiments, this extract suppresses the growth of the subcutaneous fibrosarcoma tumors. When the seed is separated into different components, the shell including the seed skin appears more potent than the inner kernel in tumor suppression. Our results suggest that the extract from the shell of Livistona chinensis may be a potential supplemental source for cancer treatment.

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November-December 2001
Volume 8 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Sartippour MR, Liu C, Shao Z, Go VL, Heber D and Nguyen M: Livistona extract inhibits angiogenesis and cancer growth. Oncol Rep 8: 1355-1357, 2001
APA
Sartippour, M.R., Liu, C., Shao, Z., Go, V.L., Heber, D., & Nguyen, M. (2001). Livistona extract inhibits angiogenesis and cancer growth. Oncology Reports, 8, 1355-1357. https://doi.org/10.3892/or.8.6.1355
MLA
Sartippour, M. R., Liu, C., Shao, Z., Go, V. L., Heber, D., Nguyen, M."Livistona extract inhibits angiogenesis and cancer growth". Oncology Reports 8.6 (2001): 1355-1357.
Chicago
Sartippour, M. R., Liu, C., Shao, Z., Go, V. L., Heber, D., Nguyen, M."Livistona extract inhibits angiogenesis and cancer growth". Oncology Reports 8, no. 6 (2001): 1355-1357. https://doi.org/10.3892/or.8.6.1355