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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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May-June 2002 Volume 9 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Article

Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?

  • Authors:
    • Giancarlo Tirelli
    • Laura Sidari
    • Vittorio Giacomarra
    • Ledia Papanikolla
    • Franco Sasso
    • Mario Russolo
    • Mauro Melato

  • View Affiliations / Copyright

    Affiliations: Department of Otorhinolaryngology, Cattinara Hospital, I-34149 Trieste, Italy
  • Pages: 575-580
    |
    Published online on: May 1, 2002
       https://doi.org/10.3892/or.9.3.575
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Abstract

Tumour cell proliferation is an important biological prognostic parameter to be considered alongside clinical and histopathological parameters. It has been evaluated by immunohistochemistry using proliferative markers (PCNA, Ki67, etc.) and by flow cytometry considering DNA content, growth fraction (S + G2M) and S-phase fraction. Our aim was to evaluate by flow cytometry both Ki67 and S-phase fraction, S + G2M, DNA content in patients surgically treated for oral cavity and/or oropharynx carcinomas. The study, performed on archival material, analysed the significance and prognostic reliability of these biological parameters to reveal locoregional metastasis and evaluated their possible correlation with clinical and histopathological parameters. In conclusion, tumour cell proliferation seems not to be useful in revealing the presence of locoregional metastasis in oral cavity and oropharynx carcinomas. Thus, new approaches are required.

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Copy and paste a formatted citation
Spandidos Publications style
Tirelli G, Sidari L, Giacomarra V, Papanikolla L, Sasso F, Russolo M and Melato M: Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?. Oncol Rep 9: 575-580, 2002.
APA
Tirelli, G., Sidari, L., Giacomarra, V., Papanikolla, L., Sasso, F., Russolo, M., & Melato, M. (2002). Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?. Oncology Reports, 9, 575-580. https://doi.org/10.3892/or.9.3.575
MLA
Tirelli, G., Sidari, L., Giacomarra, V., Papanikolla, L., Sasso, F., Russolo, M., Melato, M."Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?". Oncology Reports 9.3 (2002): 575-580.
Chicago
Tirelli, G., Sidari, L., Giacomarra, V., Papanikolla, L., Sasso, F., Russolo, M., Melato, M."Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?". Oncology Reports 9, no. 3 (2002): 575-580. https://doi.org/10.3892/or.9.3.575
Copy and paste a formatted citation
x
Spandidos Publications style
Tirelli G, Sidari L, Giacomarra V, Papanikolla L, Sasso F, Russolo M and Melato M: Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?. Oncol Rep 9: 575-580, 2002.
APA
Tirelli, G., Sidari, L., Giacomarra, V., Papanikolla, L., Sasso, F., Russolo, M., & Melato, M. (2002). Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?. Oncology Reports, 9, 575-580. https://doi.org/10.3892/or.9.3.575
MLA
Tirelli, G., Sidari, L., Giacomarra, V., Papanikolla, L., Sasso, F., Russolo, M., Melato, M."Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?". Oncology Reports 9.3 (2002): 575-580.
Chicago
Tirelli, G., Sidari, L., Giacomarra, V., Papanikolla, L., Sasso, F., Russolo, M., Melato, M."Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?". Oncology Reports 9, no. 3 (2002): 575-580. https://doi.org/10.3892/or.9.3.575
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