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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2002 Volume 9 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Lymphatic vessels and lymphangiogenesis in female cancer: Mechanisms, clinical impact and possible implications for anti-lymphangiogenic therapies (Review)

Sebastian F. Schoppmann, Reinhard Horvat, Peter Birner
Pages: 455-460
Published online on: 01 May 2002

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Review

Internal mammary sentinel node biopsy for breast cancer: Is it practicable and relevant? (Review)

Masakuni Noguchi
Pages: 461-468
Published online on: 01 May 2002

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Article

Breast-conservation treatment for bilateral breast cancer in five Japanese women

N. Hamada, Y. Ogawa, A. Nishioka, S. Kariya, M. Terashima, S. Yoshida, N. Tochika, Y. Tanaka, M. Kumon, T. Inomata
Pages: 469-474
Published online on: 01 May 2002

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Article

An elderly patient with DCIS of the breast effectively treated with toremifene alone

N. Hamada, Y. Ogawa, A. Nishioka, S. Kariya, M. Terashima, S. Yoshida, Y. Tanaka, T. Inomata
Pages: 475-478
Published online on: 01 May 2002

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Article

Thymidine phosphorylase and dihydropyrimidine dehydrogenase levels in primary colorectal cancer show a relationship to clinical effects of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy

G. Nishimura, I. Terada, T. Kobayashi, I. Ninomiya, H. Kitagawa, S. Fushida, T. Fujimura, M. Kayahara, K. Shimizu, T. Ohta, K. Miwa
Pages: 479-482
Published online on: 01 May 2002

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Article

Endometrial cytodiagnosis using a new softcyte versus a conventional endocyte

Nobutaka Nagai, Yoshimi Uebaba, Takafumi Oshita, Kenichiro Sakata, Junko Murakami, Kazushi Shigemasa, Koso Ohama
Pages: 483-487
Published online on: 01 May 2002

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Article

Clinical significance of angiogenesis in rectal carcinoid tumors

Seiji Onogawa, Shinji Tanaka, Shiro Oka, Masao Morihara, Yasuhiko Kitadai, Masaharu Sumii, Masaharu Yoshihara, Fumio Shimamoto, Ken Haruma, Kazuaki Chayama
Pages: 489-494
Published online on: 01 May 2002

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Article

Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of human lung

N. Yoshida, H. Egami, J. Yamashita, E. Takai, Y. Tamori, N. Fujino, M. Kitaoka, J. Schalkwijk, M. Ogawa
Pages: 495-501
Published online on: 01 May 2002

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Article

Expression and prognostic significance of S100A2 protein in squamous cell carcinoma of the esophagus

I. D. Kyriazanos, M. Tachibana, D. K. Dhar, M. Shibakita, T. Ono, H. Kohno, N. Nagasue
Pages: 503-510
Published online on: 01 May 2002

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Article

Expression of intercellular adhesion molecule-1 and prognosis in colorectal cancer

K. Maeda, S.-M. Kang, T. Sawada, Y. Nishiguchi, M. Yashiro, Y. Ogawa, M. Ohira, T. Ishikawa, K. Hirakawa-YS Chung
Pages: 511-514
Published online on: 01 May 2002

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Article

Expression of dihydrodiol dehydrogenase in the resected stage I non-small cell lung cancer

Chih-Yi Chen, Chung-Ping Hsu, Nan-Yung Hsu, Chih-Shiun Shih, Tze-Yi Lin, Kuan-Chih Chow
Pages: 515-519
Published online on: 01 May 2002

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Article

Immunohistochemical expression of cytokine induced nitric oxide synthase in colorectal carcinoma

T. Nozoe, M. Yasuda, M. Honda, S. Inutsuka, D. Korenaga
Pages: 521-524
Published online on: 01 May 2002

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Article

Interleukin 8 and Flt3 ligand as markers of advanced disease in primary gastrointestinal non-Hodgkin's lymphoma

Stefan Retzlaff, Teresa Padro, Peter Koch, Elisabeth Oelmann, Norbert Lugering, Rolf M. Mesters, Wolfgang E. Berdel
Pages: 525-527
Published online on: 01 May 2002

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Article

Poly(ADP-ribose) polymerase turnover alterations do not contribute to PARP overexpression in Ewing's sarcoma cells

Robert E. Newman, Viatcheslav A. Soldatenkov, Anatoly Dritschilo, Vicente Notario
Pages: 529-532
Published online on: 01 May 2002

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Article

Prevention of methylnitrosourea-induced mammary cancers by 9-cis-retinoic acid and/or vitamin D3

Mark B. Cope, Vernon E. Steele, Isao Eto, Margaret M. Juliana, Donald L. Hill, Clinton J. Grubbs
Pages: 533-537
Published online on: 01 May 2002

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Article

New attempt of preoperative differential diagnosis of thyroid neoplasms by telomerase activity measurement

Shinichi Suzuki, Toshihiko Fukushima, Hirofumi Ami, Hitoshi Onogi, Izumi Nakamura, Seiichi Takenoshita
Pages: 539-544
Published online on: 01 May 2002

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Article

Molecular staging of pelvic surgical margins after radical prostatectomy: Comparison of RT-PCR for prostate-specific antigen and telomerase activity

Bernd Straub, Markus Muller, Hans Krause, Carsten Goessl, Mark Schrader, Rudiger Heicappell, Kurt Miller
Pages: 545-549
Published online on: 01 May 2002

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Article

Allelic deletions of Rb and L-myc in urine sediments from patients with bladder tumors or carcinoma in situ

Hanne Primdahl, Hans von der Maase, Mariann Christensen, Hans Wolf, Torben Falck Orntoft
Pages: 551-555
Published online on: 01 May 2002

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Article

Distinct promoter usage of mdm2 gene in human breast cancer

Naoki Okumura, Shigehira Saji, Hidetaka Eguchi, Shigeru Nakashima, Shigetoyo Saji, Shin-Ichi Hayashi
Pages: 557-563
Published online on: 01 May 2002

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Article

Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells

Yasuhito Kato, Tsuyoshi Yamashita, Mutsuo Ishikawa
Pages: 565-569
Published online on: 01 May 2002

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Article

Gingival metastasis in lung cancer

Motoyuki Tanaka, Akio Hiraki, Hiroshi Ueoka, Akihiro Bessho, Katsuyuki Kiura, Nagio Takigawa, Tsuyoshi Kodani, Kazuyo Miyatake, Noboru Hamada, Takumi Kishimoto, Mitsune Tanimoto, Mine Harada
Pages: 571-574
Published online on: 01 May 2002

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Article

Do Ki67, S-phase, S + G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?

Giancarlo Tirelli, Laura Sidari, Vittorio Giacomarra, Ledia Papanikolla, Franco Sasso, Mario Russolo, Mauro Melato
Pages: 575-580
Published online on: 01 May 2002

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Article

Cut-off levels of NSE to differentiate SCLC from NSCLC

Hiroaki Satoh, Hiroichi Ishikawa, Koichi Kurishima, Yuko T. Yamashita, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 581-583
Published online on: 01 May 2002

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Article

Expression of the TNF-α gene on mouse lung carcinoma cells suppresses spontaneous lung metastasis without affecting tumorigenicity

Yuji Tada, Jiyang O-Wang, Keizo Takenaga, Yuichi Takiguchi, Koichiro Tatsumi, T. Kuriyama, Masatoshi Tagawa
Pages: 585-588
Published online on: 01 May 2002

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Article

Prognostic value of combined analysis of estrogen receptor status and cellular proliferative activity in breast cancer patients with extensive lymph node metastases

Tsutomu Takashima, Naoyoshi Onoda, Tetsuro Ishikawa, Yoshinari Ogawa, Yasuyuki Kato, Yasuhisa Fujimoto, Michio Sowa, Kosei Hirakawa
Pages: 589-594
Published online on: 01 May 2002

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Article

Cross-linked collagen C- and N-telopeptides for an early diagnosis of bone metastasis from breast cancer

Konosuke Kiuchi, Takashi Ishikawa, Yohei Hamaguchi, Nobuyoshi Momiyama, Satoshi Hasegawa, Akira Ishiyama, Toshiro Kono, Takako Doi, Takashi Chishima, Hiroshi Shimada
Pages: 595-598
Published online on: 01 May 2002

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Article

Analysis of T cell receptors reactive with squamous cell carcinoma antigen SART-1 presented by the HLA-A24 molecule

K. Shimizu, Y. Yamaguchi, K. Ohta, E. Miyahara, T. Toge
Pages: 599-605
Published online on: 01 May 2002

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Review

Recent advances in the regulation of matrix metalloproteinase 2 activation: From basic research to clinical implication (Review)

Tomokazu Yoshizaki, Hiroshi Sato, Mitsuru Furukawa
Pages: 607-611
Published online on: 01 May 2002

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Article

Inhibition by long-term fermented miso of induction of gastric tumors by N-methyl-N'-nitro-N-nitrosoguanidine in CD (SD) rats

Masayuki Ohara, Huimei Lu, Katsutomo Shiraki, Yoshiyuki Ishimura, Toshihiro Uesaka, Osamu Katoh, Hiromitsu Watanabe
Pages: 613-616
Published online on: 01 May 2002

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Article

Neoangiogenesis in colon cancer: Correlation between vascular density, vascular endothelial growth factor (VEGF) and p53 protein expression

P. Faviana, L. Boldrini, R. Spisni, P. Berti, D. Galleri, R. Biondi, T. Camacci, G. Materazzi, R. Pingitore, P. Miccoli, G. Fontanini
Pages: 617-620
Published online on: 01 May 2002

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Article

The influence of pre-operative radiotherapy on the expression of p53 and adhesion molecules: Correlation with treatment results in patients with squamous cell carcinoma or adenocarcinoma

J. Pomp, J. Blom, M. Linthorst, A. H. Zwinderman, C. van Krimpen
Pages: 621-625
Published online on: 01 May 2002

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Article

Carboplatin/etoposide induces remission of metastasised malignant peripheral nerve tumours (malignant schwannoma) refractory to first-line therapy

Martin B. Steins, Hubert Serve, Michael Zuhlsdorf, Norbert Senninger, Michael Semik, Wolfgang E. Berdel
Pages: 627-630
Published online on: 01 May 2002

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Article

Detection and quantification of SV40 large T-antigen DNA in mesothelioma tissues and cell lines

Gavin J. Gordon, Chang-Jie Chen, Michael T. Jaklitsch, William G. Richards, David J. Sugarbaker, Raphael Bueno
Pages: 631-634
Published online on: 01 May 2002

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Article

Effectiveness of immunochemotherapy with PSK, a protein-bound polysaccharide, in colorectal cancer and changes of tumor marker

Shinei Kudo, Jun-Ichi Tanaka, Hiroshi Kashida, Yoshiro Tamegai, Shungo Endo, H. Yamano
Pages: 635-638
Published online on: 01 May 2002

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Article

Polymorphic CAG repeat length within the androgen receptor gene: identification of a subgroup of patients with increased risk of ovarian cancer

Manuela Santarosa, Ettore Bidoli, Angelo Gallo, Agostino Steffan, Mauro Boiocchi, Alessandra Viel
Pages: 639-644
Published online on: 01 May 2002

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Article

Clinical implications of urokinase and tissue type plasminogen activators and their inhibitor (PAI-1) in breast cancer tissue

Y. A. Luqmani, L. Temmim, A. H. Parkar, M. Mathew
Pages: 645-651
Published online on: 01 May 2002

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Article

CYP3A4 promoter variant is associated with prostate cancer risk in men with benign prostate hyperplasia

Mohammed T. Tayeb, Caroline Clark, Linda Sharp, Neva E. Haites, Patrick H. Rooney, Graeme I. Murray, Simon N.L. Payne, Howard L. McLeod
Pages: 653-655
Published online on: 01 May 2002

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Article

Prevalence of hepatitis C infection in patients with non-Hodgkin's lymphomas

Maria Chiara Chindamo, Nelson Spector, Jorge A. Segadas, Glicinia Pimenta, Bart Vanderborght, Jose Carlos Morais, Cristiane Milito, Henrique Sergio Moraes Coelho
Pages: 657-659
Published online on: 01 May 2002

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Article

Dose-intense phase II study of weekly cisplatin and epidoxorubicin plus medroxyprogesterone acetate and recombinant interleukin 2 in stage IIIB-IV non-small cell lung cancer

Giovanni Mantovani, Antonio Maccio, Carlo Mulas, Elena Massa, Clelia Madeddu, Loredana Mura, Paolo Contu, Renato Versace
Pages: 661-670
Published online on: 01 May 2002

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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