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Pathological complete response induced by the combination therapy of S-1 and 24-h infusion of cisplatin in two cases initially diagnosed as inoperable advanced gastric cancer

  • Authors:
    • Kenji Ina
    • Takae Kataoka
    • Yuuki Takeuchi
    • Tomoki Fukuoka
    • Takaya Miwa
    • Tomoko Nishio
    • Ryuichi Furuta
    • Ayako Masaki
    • Fumiko Mori
    • Satoshi Kayukawa
    • Seiji Nagao
    • Takafumi Ando
    • Hidemi Goto

  • View Affiliations

  • Published online on: August 1, 2008     https://doi.org/10.3892/or_00000001
  • Pages: 259-264
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Abstract

We report on two patients, successfully treated by the combination therapy of S-1 and 24-h infusion of cisplatin (CDDP), who were initially diagnosed with unresectable stage 4 advanced gastric cancer. Each patient had a very good clinical response and underwent curative gastrectomy after completion of 14 and 10 courses of S-1/CDDP chemotherapy, respectively. A microscopically detailed examination of surgically obtained specimens showed the complete disappearance of malignant cells in the two cases. S-1/CDDP combination therapy can, therefore, be highly active in incurable advanced gastric carcinoma.

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Journal Cover

August 2008
Volume 20 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Journal Metrics
  • Impact Factor: 4.2
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 8.4
  • CiteScore Rank: Q1: #68/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.786
  • SCImago Journal Rank (SJR): 0.812
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Spandidos Publications style
Ina K, Kataoka T, Takeuchi Y, Fukuoka T, Miwa T, Nishio T, Furuta R, Masaki A, Mori F, Kayukawa S, Kayukawa S, et al: Pathological complete response induced by the combination therapy of S-1 and 24-h infusion of cisplatin in two cases initially diagnosed as inoperable advanced gastric cancer. Oncol Rep 20: 259-264, 2008
APA
Ina, K., Kataoka, T., Takeuchi, Y., Fukuoka, T., Miwa, T., Nishio, T. ... Goto, H. (2008). Pathological complete response induced by the combination therapy of S-1 and 24-h infusion of cisplatin in two cases initially diagnosed as inoperable advanced gastric cancer. Oncology Reports, 20, 259-264. https://doi.org/10.3892/or_00000001
MLA
Ina, K., Kataoka, T., Takeuchi, Y., Fukuoka, T., Miwa, T., Nishio, T., Furuta, R., Masaki, A., Mori, F., Kayukawa, S., Nagao, S., Ando, T., Goto, H."Pathological complete response induced by the combination therapy of S-1 and 24-h infusion of cisplatin in two cases initially diagnosed as inoperable advanced gastric cancer". Oncology Reports 20.2 (2008): 259-264.
Chicago
Ina, K., Kataoka, T., Takeuchi, Y., Fukuoka, T., Miwa, T., Nishio, T., Furuta, R., Masaki, A., Mori, F., Kayukawa, S., Nagao, S., Ando, T., Goto, H."Pathological complete response induced by the combination therapy of S-1 and 24-h infusion of cisplatin in two cases initially diagnosed as inoperable advanced gastric cancer". Oncology Reports 20, no. 2 (2008): 259-264. https://doi.org/10.3892/or_00000001