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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2008 Volume 20 Issue 2

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Pathological complete response induced by the combination therapy of S-1 and 24-h infusion of cisplatin in two cases initially diagnosed as inoperable advanced gastric cancer

Kenji Ina, Takae Kataoka, Yuuki Takeuchi, Tomoki Fukuoka, Takaya Miwa, Tomoko Nishio, Ryuichi Furuta, Ayako Masaki, Fumiko Mori, Satoshi Kayukawa, Seiji Nagao, Takafumi Ando, Hidemi Goto
Pages: 259-264
Published online on: 01 August 2008

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Article

Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) correlates with cisplatin resistance in human non-small cell lung cancer xenografts

Tomoki Nakagawa, Yoshimasa Inoue, Hiroko Kodama, Hitoshi Yamazaki, Kenji Kawai, Hiroshi Suemizu, Ryota Masuda, Masayuki Iwazaki, Shunsuke Yamada, Yoshito Ueyama, Hiroshi Inoue, Masato Nakamura
Pages: 265-270
Published online on: 01 August 2008

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Article

Combinations of apoptosis and cell-cycle control biomarkers predict the outcome of human melanoma

Franca Piras, Maria Teresa Perra, Daniela Murtas, Luigi Minerba, Carlo Floris, Cristina Maxia, Paolo Demurtas, Jorge Ugalde, Domenico Ribatti, Paola Sirigu
Pages: 271-277
Published online on: 01 August 2008

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Article

Ribonucleotide reductase subunit M1 is a possible chemoresistance marker to gemcitabine in biliary tract carcinoma

Kazuma Ohtaka, Naohiko Kohya, Ken Sato, Yoshihiko Kitajima, Takao Ide, Mayumi Mitsuno, Kohji Miyazaki
Pages: 279-286
Published online on: 01 August 2008

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Article

Gene expression profiling of oral submucous fibrosis using oligonucleotide microarray

Yanjia Hu, Xinchun Jian, Jieying Peng, Xiaowen Jiang, Ning Li, Shanghui Zhou
Pages: 287-294
Published online on: 01 August 2008

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Article

Telmisartan is a potent target for prevention and treatment in human prostate cancer

Kiyoaki Funao, Masahide Matsuyama, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Tatsuya Nakatani, Rikio Yoshimura
Pages: 295-300
Published online on: 01 August 2008

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Article

Expression analysis of the autosomal recessive primary microcephaly genes MCPH1 (microcephalin) and MCPH5 (ASPM, abnormal spindle-like, microcephaly associated) in human malignant gliomas

Carsten Hagemann, Jelena Anacker, Stefanie Gerngras, Siglinde Kühnel, Harun M. Said, Rajnikant Patel, Ulrike Kämmerer, Dirk Vordermark, Klaus Roosen, Giles Hamilton Vince
Pages: 301-308
Published online on: 01 August 2008

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Article

The role of tumor vascularisation in benign and malignant cardiovascular neoplasms: A comparison of cardiac myxoma and sarcomas of the pulmonary artery

Andreas Gaumann, Gerson Strubel, Beata Bode-Lesniewska, Irene Schmidtmann, Jörg Kriegsmann, C. James Kirkpatrick
Pages: 309-318
Published online on: 01 August 2008

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Article

Diallyl sulfide inhibits PhIP-induced cell death via the inhibition of DNA strand breaks in normal human breast epithelial cells

Ayoola Aboyade-Cole, Selina Darling-Reed, Ebenezer Oriaku, Michael McCaskill, Ronald Thomas
Pages: 319-323
Published online on: 01 August 2008

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Article

S100P contributes to chemosensitivity of human ovarian cancer cell line OVCAR3

Zhijuan He, Jianhua Gao, Qi Wang, Min Liu, Yixuan Li, Xin Li, Hua Tang, Jianhua Zheng
Pages: 325-332
Published online on: 01 August 2008

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Article

Human papillomavirus type 16 and 18 infection is associated with lung cancer patients from the central part of China

Yongping Wang, Aifeng Wang, Rui Jiang, Huaxiong Pan, Bangxing Huang, Yan Lu, Cuihuan Wu
Pages: 333-339
Published online on: 01 August 2008

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Article

Transfection of the DAAO gene and subsequent induction of cytotoxic oxidative stress by D-alanine in 9L cells

Jun Li, Yuechun Shen, Anzhong Liu, Xiaoming Wang, Chaochen Zhao
Pages: 341-346
Published online on: 01 August 2008

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Article

Hedgehog-Patched pathway aberrations in a malignant triton tumor case study

Miljenko Bura, Vesna Musani, Maja Cretnik, Iva Botica, Sonja Levanat
Pages: 347-352
Published online on: 01 August 2008

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Article

Significance of trans-hepatic arterial chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombus

Motohisa Akiyama, Hisamitsu Miyaaki, Satoshi Miuma, Hidetaka Shibata, Masumi Fujimoto, Shigeyuki Takeshita, Eisuke Ozawa, Tatsuki Ichikawa, Kazuhiko Nakao, Katsumi Eguchi
Pages: 353-357
Published online on: 01 August 2008

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Article

Clinicopathological significance of the gene expression of matrix metalloproteinase-7, insulin-like growth factor-1, insulin-like growth factor-2 and insulin-like growth factor-1 receptor in patients with colorectal cancer: Insulin-like growth factor-1 receptor gene expression is a useful predictor of liver metastasis from colorectal cancer

Takashi Oshima, Makoto Akaike, Kazue Yoshihara, Manabu Shiozawa, Naoto Yamamoto, Tsutomu Sato, Roppei Yamada, Shoich Fujii, Yasushi Rino, Chikara Kunisaki, Katsuaki Tanaka, Munetaka Masuda, Toshio Imada
Pages: 359-364
Published online on: 01 August 2008

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Article

Efficacy of doxorubicin thermosensitive liposomes (40°C) and local hyperthermia on rat rhabdomyosarcoma

Kotaro Morita, Friedrich Zywietz, Kenichi Kakinuma, Ryuichi Tanaka, Masashi Katoh
Pages: 365-372
Published online on: 01 August 2008

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Article

Antitumor effect of gefitinib on head and neck squamous cell carcinoma enhanced by trastuzumab

Norio Kondo, Yukari Ishiguro, Machiko Kimura, Daisuke Sano, Kyoko Fujita, Atsuko Sakakibara, Takahide Taguchi, Gabor Toth, Hideki Matsuda, Mamoru Tsukuda
Pages: 373-378
Published online on: 01 August 2008

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Article

Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases

Jung-Hyun Park, Eun-Jung Kim, Hye-Yeon Jang, Heyok Shim, Kang-Kyoo Lee, Hyang-Jeong Jo, Hwi-Jung Kim, Sei-Hoon Yang, Eun-Taik Jeong, Hak-Ryul Kim
Pages: 379-384
Published online on: 01 August 2008

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Article

Vascular endothelial growth factor monitoring in advanced hepatocellular carcinoma patients treated with radiofrequency ablation plus octreotide: A single center experience

L. Montella, R. Addeo, M. Caraglia, V. Faiola, R. Guarrasi, B. Vincenzi, A. Palmeri, E. Capasso, V. Nocera, L. Tarantino, M. Ariete, A. Martorelli, S. Del Prete
Pages: 385-390
Published online on: 01 August 2008

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Article

Key promoter elements involved in transcriptional activation of the cancer-related gene coding for S100P calcium-binding protein

Adriana Gibadulinova, Ingrid Oveckova, Seppo Parkkila, Silvia Pastorekova, Jaromir Pastorek
Pages: 391-396
Published online on: 01 August 2008

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Article

Enhancement of sodium butyrate-induced cell death and apoptosis by X-irradiation in the human colorectal cancer cell line HCT 116

Zheng-Li Wei, Qing-Li Zhao, Da-Yong Yu, Mariame A. Hassan, Takaharu Nomura, Takashi Kondo
Pages: 397-403
Published online on: 01 August 2008

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Article Open Access

Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma

Makoto Arai, Fumio Imazeki, Yuzo Sakai, Rintaro Mikata, Motohisa Tada, Naohiko Seki, Hideaki Shimada, Takenori Ochiai, Osamu Yokosuka
Pages: 405-412
Published online on: 01 August 2008

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Article

Rapid detection of the hypoxia-regulated CA-IX and NDRG1 gene expression in different glioblastoma cells in vitro

Harun M. Said, Buelent Polat, Adrian Staab, Carsten Hagemann, Susanne Stein, Michael Flentje, Mathias Theobald, Astrid Katzer, Dirk Vordermark
Pages: 413-419
Published online on: 01 August 2008

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Article

Expression of TMEM87B interacting with the human papillomavirus type 18 E6 oncogene in the Hela cDNA library by a yeast two-hybrid system

Shuang Li, Ping Liu, Lin Xi, Xuefeng Jiang, Mingfu Wu, Dongrui Deng, Juncheng Wei, Tao Zhu, Li Zhou, Shixuan Wang, Gang Xu, Li Meng, Jianfeng Zhou, Ding Ma
Pages: 421-427
Published online on: 01 August 2008

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Article

High corn oil and high extra virgin olive oil diets have different effects on the expression of differentiation-related genes in experimental mammary tumors

Raquel Moral, Montserrat Solanas, Gemma Garcia, Laura Grau, Elena Vela, Raquel Escrich, Eduard Escrich
Pages: 429-435
Published online on: 01 August 2008

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Article

mda-7/IL-24 induces apoptosis in human HepG2 hepatoma cells by endoplasmic reticulum stress

Xiaofeng Zhang, Xiaoyan Kang, Lehua Shi, Jin Li, Wen Xu, Haihua Qian, Mengchao Wu, Zhengfeng Yin
Pages: 437-442
Published online on: 01 August 2008

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Article

Immunotherapy with irradiated autologous leukemic cells in patients with B-CLL in early stages

Iwona Hus, Jerzy Kawiak, Jacek Tabarkiewicz, Sebastian Radej, Grazyna Hoser, Agnieszka Bojarska-Junak, Michael Schmitt, Krzysztof Giannopoulos, Anna Dmoszynska, Jacek Rolinski
Pages: 443-451
Published online on: 01 August 2008

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Article

Number of Negative Points: A novel method for predicting radiosensitivity in head and neck tumor cell lines

Lovisa Farnebo, Fredrik Jerhammar, Linda Vainikka, Reidar Grénman, Lena Norberg-Spaak, Karin Roberg
Pages: 453-461
Published online on: 01 August 2008

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Article

Outcome of relapses of nephroblastoma in patients registered in the SIOP/GPOH trials and studies

Harald Reinhard, Andrea Schmidt, Rhoikos Furtwängler, Ivo Leuschner, Christian Rübe, Dietrich Von Schweinitz, Andreas Zoubek, Felix Niggli, Norbert Graf
Pages: 463-467
Published online on: 01 August 2008

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Article

Activation of the hTERT expression in squamous cell cervical carcinoma is not associated with gene amplification

Ekaterina Anedchenko, Nina Oparina, Alexei Dmitriev, George Krasnov, Larisa Pavlova, Natalya Alexandrova, Fjodor Kisseljov, Vera Senchenko
Pages: 469-474
Published online on: 01 August 2008

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

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Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
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