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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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January 2010 Volume 23 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Article

State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma

  • Authors:
    • Masanobu Yamatoji
    • Atsushi Kasamatsu
    • Yukio Yamano
    • Kentaro Sakuma
    • Kenji Ogoshi
    • Manabu Iyoda
    • Keiji Shinozuka
    • Katsunori Ogawara
    • Yuichi Takiguchi
    • Masashi Shiiba
    • Hideki Tanzawa
    • Katsuhiro Uzawa
  • View Affiliations / Copyright

    Affiliations: Department of Clinical Molecular Biology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan
  • Pages: 61-67
    |
    Published online on: January 1, 2010
       https://doi.org/10.3892/or_00000606
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Abstract

Homeobox (HOX) A10, the regulator of embryonic morphogenesis and differentiation, is aberrantly expressed in several cancer types. Our previous study using microarray technology showed that significant up-regulation of HOXA10 occurs in oral squamous cell carcinoma (OSCC)-derived cell lines compared to human normal oral keratinocytes (HNOKs). The aim of the current study was to examine the status of HOXA10 mRNA and protein expression in OSCC-derived cell lines and human primary OSCCs. HOXA10 mRNA was up-regulated in six OSCC-derived cell lines compared with HNOKs and in primary OSCCs by using real-time quantitative reverse transcriptase-polymerase chain reaction. Immunohistochemistry data indicated that HOXA10 protein expression levels were consistent with mRNA expression status in OSCC-derived cell lines and primary OSCCs. Furthermore, HOXA10 expression status was correlated with the TNM stage (P<0.05). These results indicate that HOXA10 expression could contribute to cancer progression and prognosis and that HOXA10 may be a potential diagnostic marker and a therapeutic target for OSCCs.

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Copy and paste a formatted citation
Spandidos Publications style
Yamatoji M, Kasamatsu A, Yamano Y, Sakuma K, Ogoshi K, Iyoda M, Shinozuka K, Ogawara K, Takiguchi Y, Shiiba M, Shiiba M, et al: State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma. Oncol Rep 23: 61-67, 2010.
APA
Yamatoji, M., Kasamatsu, A., Yamano, Y., Sakuma, K., Ogoshi, K., Iyoda, M. ... Uzawa, K. (2010). State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma. Oncology Reports, 23, 61-67. https://doi.org/10.3892/or_00000606
MLA
Yamatoji, M., Kasamatsu, A., Yamano, Y., Sakuma, K., Ogoshi, K., Iyoda, M., Shinozuka, K., Ogawara, K., Takiguchi, Y., Shiiba, M., Tanzawa, H., Uzawa, K."State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma". Oncology Reports 23.1 (2010): 61-67.
Chicago
Yamatoji, M., Kasamatsu, A., Yamano, Y., Sakuma, K., Ogoshi, K., Iyoda, M., Shinozuka, K., Ogawara, K., Takiguchi, Y., Shiiba, M., Tanzawa, H., Uzawa, K."State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma". Oncology Reports 23, no. 1 (2010): 61-67. https://doi.org/10.3892/or_00000606
Copy and paste a formatted citation
x
Spandidos Publications style
Yamatoji M, Kasamatsu A, Yamano Y, Sakuma K, Ogoshi K, Iyoda M, Shinozuka K, Ogawara K, Takiguchi Y, Shiiba M, Shiiba M, et al: State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma. Oncol Rep 23: 61-67, 2010.
APA
Yamatoji, M., Kasamatsu, A., Yamano, Y., Sakuma, K., Ogoshi, K., Iyoda, M. ... Uzawa, K. (2010). State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma. Oncology Reports, 23, 61-67. https://doi.org/10.3892/or_00000606
MLA
Yamatoji, M., Kasamatsu, A., Yamano, Y., Sakuma, K., Ogoshi, K., Iyoda, M., Shinozuka, K., Ogawara, K., Takiguchi, Y., Shiiba, M., Tanzawa, H., Uzawa, K."State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma". Oncology Reports 23.1 (2010): 61-67.
Chicago
Yamatoji, M., Kasamatsu, A., Yamano, Y., Sakuma, K., Ogoshi, K., Iyoda, M., Shinozuka, K., Ogawara, K., Takiguchi, Y., Shiiba, M., Tanzawa, H., Uzawa, K."State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma". Oncology Reports 23, no. 1 (2010): 61-67. https://doi.org/10.3892/or_00000606
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