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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2010 Volume 23 Issue 1

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Anticancer bioactive peptide suppresses human gastric cancer growth through modulation of apoptosis and the cell cycle

Liya Su, Guihua Xu, Jie Shen, Ya Tuo, Xingguang Zhang, Shuqin Jia, Zhong Chen, Xiulan Su
Pages: 3-9
Published online on: 01 January 2010

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Article

The ubiquitin-like molecule interferon-stimulated gene 15 is overexpressed in human prostate cancer

Hirofumi Satake, Kenji Tamura, Mutsuo Furihata, Takashi Anchi, Hatsune Sakoda, Chiaki Kawada, Tatsuo Iiyama, Shingo Ashida, Taro Shuin
Pages: 11-16
Published online on: 01 January 2010

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Article

The stem cell marker nestin predicts poor prognosis in human melanoma

Franca Piras, Maria Teresa Perra, Daniela Murtas, Luigi Minerba, Carlo Floris, Cristina Maxia, Paolo Demurtas, Jorge Ugalde, Domenico Ribatti, Paola Sirigu
Pages: 17-24
Published online on: 01 January 2010

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Article

Molecular analysis of single isolated glands in gastric cancers and their surrounding gastric intestinal metaplastic mucosa

Tamotsu Sugai, Wataru Habano, Yu-Fei Jiao, Minoru Toyota, Hiromu Suzuki, Mitsunori Tsukahara, Hitohiko Koizuka, Risaburo Akasaka, Keisuke Koeda, Go Wakabayashi, Kazuyuki Suzuki
Pages: 25-33
Published online on: 01 January 2010

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Article

Notch pathway as candidate therapeutic target in Her2/Neu/ErbB2 receptor-negative breast tumors

Hajime Hirose, Hideshi Ishii, Koshi Mimori, Daisuke Ohta, Masahisa Ohkuma, Hirohiko Tsujii, Toshiyuki Saito, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori
Pages: 35-43
Published online on: 01 January 2010

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Article

Expression status of S100A14 and S100A4 correlates with metastatic potential and clinical outcome in colorectal cancer after surgery

Hong-Yi Wang, Jing-Yu Zhang, Jian-Tao Cui, Xiao-Hui Tan, Wen-Mei Li, Jin Gu, You-Yong Lu
Pages: 45-52
Published online on: 01 January 2010

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Article

Chemopreventive effect of fermented brown rice and rice bran (FBRA) on the inflammation-related colorectal carcinogenesis in ApcMin/+ mice

Suphot Phutthaphadoong, Yasuhiro Yamada, Akihiro Hirata, Hiroyuki Tomita, Akira Hara, Pornngarm Limtrakul, Teruaki Iwasaki, Hiroshi Kobayashi, Hideki Mori
Pages: 53-59
Published online on: 01 January 2010

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Article

State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma

Masanobu Yamatoji, Atsushi Kasamatsu, Yukio Yamano, Kentaro Sakuma, Kenji Ogoshi, Manabu Iyoda, Keiji Shinozuka, Katsunori Ogawara, Yuichi Takiguchi, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa
Pages: 61-67
Published online on: 01 January 2010

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Article Open Access

Expression of matrix metalloproteinase-26 promotes human glioma U251 cell invasion in vitro and in vivo

Yiping Deng, Wei Li, Yilei Li, Hongfa Yang, Hua Xu, Shanshan Liang, Lihong Zhang, Yulin Li
Pages: 69-78
Published online on: 01 January 2010

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Article

Na+/H+ exchanger blockade inhibits the expression of vascular endothelial growth factor in SGC7901 cells

Bingyan He, Ming Zhang, Rui Zhu
Pages: 79-87
Published online on: 01 January 2010

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Article

Effects and action mechanism of Diospyros kaki on the differentiation of human leukemia HL-60 cells

Seung Hyun Kim, Seung Sik Cho, Jaya Ram Simkhada, Sung Ju Park, Hyo Jeong Lee, Tae Sung Kim, Jin Cheol Yoo
Pages: 89-95
Published online on: 01 January 2010

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Article

Enhanced tumor radiosensitivity by a survivin dominant-negative mutant

Qing-Zhong Yuan, Chun-Ting Wang, Yong-Qiu Mao, Peng Zhang, Hua-Shan Shi, Zhi-Yong Li, Li Pan, Dan-Dan Yu, Fei Leng, Xiang Chen, Wei Ying, Jing-Hui Xu, Wei Li, Fan Wu, Yuan Wen, Tian-Tai Ma, Yu-Quan Wei
Pages: 97-103
Published online on: 01 January 2010

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Article

Isolation and characterization of lymphatic endothelial cells from human glossal lymphangioma

Lanying You, Mingfu Wu, Ying Chen, Gang Xu, Juncheng Wei, Qiong Li, Anping Song, Liangpin Zhao, Shuang Li, Zhiqiang Han, Jianfeng Zhou, Yunpin Lu, Shixuan Wang, Ding Ma, Li Meng
Pages: 105-111
Published online on: 01 January 2010

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Article

High expression of microRNA-15b predicts a low risk of tumor recurrence following curative resection of hepatocellular carcinoma

Goh Eun Chung, Jung-Hwan Yoon, Sun Jung Myung, Jeong-Hoon Lee, Sung-Hee Lee, Soo-Mi Lee, Seung-Jun Kim, Seung Yong Hwang, Hyo-Suk Lee, Chung Yong Kim
Pages: 113-119
Published online on: 01 January 2010

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Article

5-Fluorouracil and oxaliplatin modify the expression profiles of microRNAs in human colon cancer cells in vitro

Jianfeng Zhou, Yanping Zhou, Bin Yin, Wei Hao, Lin Zhao, Wenyi Ju, Chunmei Bai
Pages: 121-128
Published online on: 01 January 2010

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Article

Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells

Haitao Zhu, Jicui Zheng, Xianmin Xiao, Shan Zheng, Kuiran Dong, Jiangbin Liu, Yang Wang
Pages: 129-139
Published online on: 01 January 2010

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Article

Co-elevated expression of hepatocyte growth factor and interleukin-8 contributes to poor prognosis of patients with primary nasopharyngeal carcinoma

Li-Qiong Xie, Li-Juan Bian, Zhi Li, Yang Li, Ying-Jie Liang
Pages: 141-150
Published online on: 01 January 2010

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Article

The mitogenic effectors of isoproterenol in human hepatocellular carcinoma cells

Aihua Yuan, Zongfang Li, Xinqiu Li, Shanyong Yi, Shukui Wang, Yongdong Cai, Hongyong Cao
Pages: 151-157
Published online on: 01 January 2010

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Article

Activation of mTOR in renal cell carcinoma is due to increased phosphorylation rather than protein overexpression

Stephan Kruck, Jens Bedke, Jörg Hennenlotter, Petra A. Ohneseit, Ursula Kuehs, Erika Senger, Karl-Dietrich Sievert, Arnulf Stenzl
Pages: 159-163
Published online on: 01 January 2010

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Article

Etoposide induces growth arrest and disrupts androgen receptor signaling in prostate cancer cells

Shicheng Liu, Hitoshi Yamauchi
Pages: 165-170
Published online on: 01 January 2010

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Article

Synergistic inhibition of human colon cancer cell growth by the cannabinoid CB1 receptor antagonist rimonabant and oxaliplatin

Patrizia Gazzerro, Anna M. Malfitano, Maria Chiara Proto, Antonietta Santoro, Simona Pisanti, Maria Gabriella Caruso, Maria Notarnicola, Caterina Messa, Chiara Laezza, Gabriella Misso, Michele Caraglia, Maurizio Bifulco
Pages: 171-175
Published online on: 01 January 2010

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Article

Wnt-5a regulates proliferation in lung cancer cells

Ying Huang, Guangxiang Liu, Bo Zhang, Gang Xu, Wei Xiong, Heping Yang
Pages: 177-181
Published online on: 01 January 2010

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Article

Down-regulation of MTUS1 in human colon tumors

Christina Zuern, Jutta Heimrich, Roland Kaufmann, Konrad K. Richter, Utz Settmacher, Christoph Wanner, Jan Galle, Stefan Seibold
Pages: 183-189
Published online on: 01 January 2010

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Article

CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients

Masatsugu Hiraki, Yoshihiko Kitajima, Yuji Nakafusa, Jun Nakamura, Kazuyoshi Hashiguchi, Kenji Sumi, Hirokazu Noshiro, Kohji Miyazaki
Pages: 191-197
Published online on: 01 January 2010

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Article

p53 independent radio-sensitization of human lymphoblastoid cell lines by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin

Yoshihiro Fujii, Takamitsu Kato, Nobuo Kubota, Akira Fujimori, Ohtsura Niwa, Ryuichi Okayasu
Pages: 199-203
Published online on: 01 January 2010

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Article

Anti-tumor effects of AMT in the renal cell carcinoma model

Marcello Caballero, Jürgen Scheele, Ute Zirrgiebel, Norbert Esser, Christoph Schächtele, Jens Soltau, Jochen Rentschler, Klaus Diergarten, Joachim Drevs
Pages: 205-210
Published online on: 01 January 2010

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Article

Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells

Xuan-Bin Wang, Shan-Shan Wang, Qiu-Fang Zhang, Ming Liu, Hong-Liang Li, Ying Liu, Jia-Ning Wang, Fei Zheng, Ling-Yun Guo, Ji-Zhou Xiang
Pages: 211-215
Published online on: 01 January 2010

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Article

Imatinib mesylate (STI571) enhances amrubicin-induced cytotoxic activity through inhibition of the phosphatidylinositol 3-kinase/Akt pathway in small cell lung cancer cells

Hisashi Suyama, Tadashi Igishi, Yasuto Ueda, Yasushi Shigeoka, Masahiro Kodani, Masato Morita, Kenichi Takeda, Takashi Sumikawa, Hirofumi Nakazaki, Keiji Matsunami, Shingo Matsumoto, Eiji Shimizu
Pages: 217-222
Published online on: 01 January 2010

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Article

ERCC1 and XPF expression in human testicular germ cell tumors

Beate Köberle, Walburgis Brenner, Andreas Albers, Svetlana Usanova, Joachim W. Thüroff, Bernd Kaina
Pages: 223-227
Published online on: 01 January 2010

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Article

The sesquiterpene lactone eupatolide sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression

Jongkyu Lee, Cheol Hwangbo, Jung Joon Lee, Juhee Seo, Jeong-Hyung Lee
Pages: 229-237
Published online on: 01 January 2010

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Article

Involvement of p21Waf1/Cip1 cleavage during roscovitine-induced apoptosis in non-small cell lung cancer cells

Tao Zhang, Tao Jiang, Feng Zhang, Chen Li, Yong-An Zhou, Yi-Fang Zhu, Xiao-Fei Li
Pages: 239-245
Published online on: 01 January 2010

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Article

Vascular damage in testicular cancer patients: A study on endothelial activation by bleomycin and cisplatin in vitro

Janine Nuver, Esther C. De Haas, Martine Van Zweeden, Jourik A. Gietema, Coby Meijer
Pages: 247-253
Published online on: 01 January 2010

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Article

Hypoxia activates heparanase expression in an NF-κB dependent manner

Wujun Wu, Cheng'en Pan, Kewei Meng, Lin Zhao, Lixue Du, Qingguang Liu, Rong Lin
Pages: 255-261
Published online on: 01 January 2010

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Article

HDAC inhibition radiosensitizes human normal tissue cells and reduces DNA double-strand break repair capacity

Jan C. Purrucker, Andreas Fricke, Mei Fang Ong, Christian Rübe, Claudia E. Rübe, Ulrich Mahlknecht
Pages: 263-269
Published online on: 01 January 2010

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Article

Association of the ABCB1 3435C>T polymorphism and treatment outcomes in advanced gastric cancer patients treated with paclitaxel-based chemotherapy

Hyun Chang, Sun Young Rha, Hei-Cheul Jeung, Chong Kun Im, Sung Hoon Noh, Jin Ju Kim, Hyun Cheol Chung
Pages: 271-278
Published online on: 01 January 2010

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Article

Resveratrol down-regulates survivin and induces apoptosis in human multidrug-resistant SPC-A-1/CDDP cells

Weiguo Zhao, Pengtao Bao, Haowen Qi, Houcheng You
Pages: 279-286
Published online on: 01 January 2010

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Article

Pyrogallol-induced endothelial cell death is related to GSH depletion rather than ROS level changes

Yong Hwan Han, Hwa Jin Moon, Bo Ra You, Sung Zoo Kim, Suhn Hee Kim, Woo Hyun Park
Pages: 287-292
Published online on: 01 January 2010

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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