Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan (Review)

  • Authors:
    • Isao Okazaki
    • Minoru Sugita
    • Hideaki Matsuki
    • Syed Muhammad Baqui Billah
    • Tetsu Watanabe
  • View Affiliations

  • Published online on: June 1, 2010     https://doi.org/10.3892/or_00000788
  • Pages: 1493-1500
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Abstract

The polymorphism of CYP1A1*2A or CYP1A1*2B, and the linkage of CYP1A1*2A, CYP1A1*2B, GSTM1 and GSTT1 polymorphisms have been established as susceptible genes or gene-gene interactions of tobacco-related lung cancer. New candidate genes susceptible for lung cancer such as NQO1 (NAD(P)H:quinine oxidoreductase), NAT2 (N-acetyltransferase 2), and several others have been reported. In the present review we focus on new candidate genes susceptible for lung cancer, then examine all Japanese references by meta-analysis on susceptible genes over the past 20 years, and discuss whether new candidates and changing trend in Japan could be caused by environmental change.

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June 2010
Volume 23 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Okazaki I, Sugita M, Matsuki H, Billah SM and Watanabe T: Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan (Review) . Oncol Rep 23: 1493-1500, 2010
APA
Okazaki, I., Sugita, M., Matsuki, H., Billah, S.M., & Watanabe, T. (2010). Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan (Review) . Oncology Reports, 23, 1493-1500. https://doi.org/10.3892/or_00000788
MLA
Okazaki, I., Sugita, M., Matsuki, H., Billah, S. M., Watanabe, T."Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan (Review) ". Oncology Reports 23.6 (2010): 1493-1500.
Chicago
Okazaki, I., Sugita, M., Matsuki, H., Billah, S. M., Watanabe, T."Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan (Review) ". Oncology Reports 23, no. 6 (2010): 1493-1500. https://doi.org/10.3892/or_00000788