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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2010 Volume 23 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

HSP90 and its inhibitors (Review)

Huifang Hao, Yoshio Naomoto, Xiaohong Bao, Nobuyuki Watanabe, Kazufumi Sakurama, Kazuhiro Noma, Takayuki Motoki, Yasuko Tomono, Takuya Fukazawa, Yasuhiro Shirakawa, Tomoki Yamatsuji, Junji Matsuoka, Munenori Takaoka
Pages: 1483-1492
Published online on: 01 June 2010

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Article

Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan (Review)

Isao Okazaki, Minoru Sugita, Hideaki Matsuki, Syed Muhammad Baqui Billah, Tetsu Watanabe
Pages: 1493-1500
Published online on: 01 June 2010

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Article Open Access

Comparative transcriptional study of the effects of high intracellular zinc on prostate carcinoma cells

Pooi-Fong Wong, Sazaly Abubakar
Pages: 1501-1516
Published online on: 01 June 2010

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Article Open Access

Anticancer activity of phenoxazines produced by bovine erythrocytes on colon cancer cells

Takeshi Nakachi, Takafumi Tabuchi, Akira Takasaki, Sadao Arai, Keisuke Miyazawa, Akio Tomoda
Pages: 1517-1522
Published online on: 01 June 2010

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Article

Effect of Helicobacter pylori infection on the sonic hedgehog signaling pathway in gastric cancer cells

Jie-Hyun Kim, Yeun Jung Choi, Sang Hun Lee, Hyun Soo Shin, In Ohk Lee, Yu Jin Kim, Hyunki Kim, Woo Ick Yang, Hoguen Kim, Yong Chan Lee
Pages: 1523-1528
Published online on: 01 June 2010

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Article

Potentiation of gemcitabine by Turmeric Force™ in pancreatic cancer cell lines

Cheppail Ramachandran, Anna P. Resek, Enrique Escalon, Anat Aviram, Steven J. Melnick
Pages: 1529-1535
Published online on: 01 June 2010

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Article

Created Gli-1 duplex short-RNA (i-Gli-RNA) eliminates CD44Hi progenitors of taxol-resistant ovarian cancer cells

Takashi Mine, Satoko Matsueda, Hui Gao, Yufeng Li, Kwong-Kwok Wong, George E. Peoples, Soldano Ferrone, Constantin G. Ioannides
Pages: 1537-1543
Published online on: 01 June 2010

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Article

Silibinin reverses epithelial-to-mesenchymal transition in metastatic prostate cancer cells by targeting transcription factors

Kaijie Wu, Jin Zeng, Lei Li, Jinhai Fan, Dong Zhang, Yan Xue, Guodong Zhu, Lin Yang, Xinyang Wang, Dalin He
Pages: 1545-1552
Published online on: 01 June 2010

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Article

IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1

Ronghui Li, Gang Li, Lin Deng, Qinglin Liu, Jun Dai, Jie Shen, Jian Zhang
Pages: 1553-1559
Published online on: 01 June 2010

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Article

Chemokines mediate mesenchymal stem cell migration toward gliomas in vitro

Feng Xu, Jinlong Shi, Bin Yu, Wei Ni, Xing Wu, Zhikai Gu
Pages: 1561-1567
Published online on: 01 June 2010

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Article

Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression

Yamei Ma, Guohua Zhang, Xiangsheng Fu, Oudong Xia, Chunling Zhan, Lianjie Li, Zhiqing Wang, Baoping Wu
Pages: 1569-1576
Published online on: 01 June 2010

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Article

Potential of molecular targeted therapy of HER-2 and Cox-2 for invasive transitional cell carcinoma of the urinary bladder

Katsuya Naruse, Yoshiaki Yamada, Kogenta Nakamura, Shigeyuki Aoki, Tomohiro Taki, Kenji Zennami, Remi Katsuda, Masahito Watanabe, Genya Nishikawa, Youko Itoh, Kenji Mitsui, Hatsuki Hibi, Nobuaki Honda
Pages: 1577-1583
Published online on: 01 June 2010

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Article

Combination therapy with Gamma Knife radiosurgery and antisense EGFR for malignant glioma in vitro and orthotopic xenografts

Yanhe Li, Qiang Jia, Junxia Zhang, Lei Han, Desheng Xu, Anling Zhang, Yipei Zhang, Zhiyuan Zhang, Peiyu Pu, Chunsheng Kang
Pages: 1585-1591
Published online on: 01 June 2010

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Article

PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway

Tao Tian, Ke-Jun Nan, Hui Guo, Wen-Juan Wang, Zhi-Ping Ruan, Shu-Hong Wang, Xuan Liang, Chuang-Xin Lu
Pages: 1593-1600
Published online on: 01 June 2010

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Article

Hepatocytic precursor (stem-like) WB-F344 cells reduce tumorigenicity of hepatoma CBRH-7919 cells via TGF-β/Smad pathway

Wei-Qing Li, Yi-Ming Li, Jia Guo, Yu-Ming Liu, Xiao-Qun Yang, Hui-Juan Ge, Yi Xu, Hui-Min Liu, Jin He, Hong-Yu Yu
Pages: 1601-1607
Published online on: 01 June 2010

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Article

α1,3 Fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24

Wenhua Li, Wen Zhang, Jianming Luo, Ayong Cao, Ying Zhang, Dan Huang, Weiqi Sheng, Sanjun Cai, Jin Li
Pages: 1609-1617
Published online on: 01 June 2010

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Article

Screening and analysis of pathogenic genes during DMBA-induced buccal mucosa carcinogenesis in golden hamsters

Kai Yang, Guodong Zhang, Jie Mei, Dan Chen, Mingjun Wu
Pages: 1619-1624
Published online on: 01 June 2010

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Article

Expression of microRNAs in squamous cell carcinoma of human head and neck and the esophagus: miR-205 and miR-21 are specific markers for HNSCC and ESCC

Sotai Kimura, Seiji Naganuma, Dai Susuki, Yasuo Hirono, Akio Yamaguchi, Shigeharu Fujieda, Kazuo Sano, Hiroshi Itoh
Pages: 1625-1633
Published online on: 01 June 2010

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Article

Triplet schedule of weekly 5-Fluorouracil and alternating irinotecan or oxaliplatin in advanced colorectal cancer: A dose-finding and phase II study

M. F. Morelli, A. Santomaggio, E. Ricevuto, K. Cannita, F. De Galitiis, M. Tudini, G. Bruera, M. Mancini, M. Pelliccione, F. Calista, F. Guglielmi, F. Martella, P. Lanfiuti Baldi, G. Porzio, A. Russo, N. Gebbia, S. Iacobelli, P. Marchetti, C. Ficorella
Pages: 1635-1640
Published online on: 01 June 2010

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Article

Histological features of extratumoral breast lesions as a predictive factor of familial breast cancer

Anita Mangia, Stefania Tommasi, Michele Bruno, Andrea Malfettone, Cosimo D'Amico, Francesco Alfredo Zito, Angelo Paradiso, Giovanni Simone
Pages: 1641-1645
Published online on: 01 June 2010

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Article

The ratio of serum placenta growth factor to soluble vascular endothelial growth factor receptor-1 predicts the prognosis of hepatocellular carcinoma

Sakae Nagaoka, Takafumi Yoshida, Junji Akiyoshi, Jun Akiba, Takao Hisamoto, Yoko Yoshida, Mitsuhiko Abe, Hironori Koga, Takuji Toirimura, Takato Ueno, Michio Sata
Pages: 1647-1654
Published online on: 01 June 2010

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Article

Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: A Portuguese multicentre study

Bruno M. Costa, Cláudia Caeiro, Inês Guimarães, Olga Martinho, Teresa Jaraquemada, Isabel Augusto, Lígia Castro, Lígia Osório, Paulo Linhares, Mrinalini Honavar, Mário Resende, Fátima Braga, Ana Silva, Fernando Pardal, Júlia Amorim, Rui Nabiço, Rui Almeida, Carlos Alegria, Manuel Pires, Célia Pinheiro, Ernesto Carvalho, José M. Lopes, Paulo Costa, Margarida Damasceno, Rui M. Reis
Pages: 1655-1662
Published online on: 01 June 2010

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Article

Conformal radiotherapy of prostate cancer: What is the proper technique for sparing organs-at-risk?

V. Peppa, M. Mazonakis, S. Kachris, C. Varveris, J. Damilakis
Pages: 1663-1668
Published online on: 01 June 2010

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Article

FHL2 suppresses growth and differentiation of the colon cancer cell line HT-29

Thomas Amann, Yvonne Egle, Anja-Katrin Bosserhoff, Claus Hellerbrand
Pages: 1669-1674
Published online on: 01 June 2010

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Article

The role of hLHX6-HMR as a methylation biomarker for early diagnosis of cervical cancer

Samil Jung, Dongjun Jeong, Jinsun Kim, Lisha Yi, Keunhoe Koo, Jaehyouk Lee, Soon-Duck Lee, Jin-Wha Park, Boogi Chang, Chang-Hwan Kim, Chang-Jin Kim, Myeong-Sok Lee
Pages: 1675-1682
Published online on: 01 June 2010

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Article

Identification of pancreatic juice proteins as biomarkers of pancreatic cancer

Jun Gao, Feng Zhu, Shunli Lv, Zhaoshen Li, Zhang Ling, Yanfang Gong, Chen Jie, Lie Ma
Pages: 1683-1692
Published online on: 01 June 2010

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Article

miRNA-regulated expression of oncogenes and tumor suppressor genes in the cisplatin-inhibited growth of K562 cells

Shu-Yang Xie, You-Jie Li, Ping-Yu Wang, Fei Jiao, Shuai Zhang, Wen-Juan Zhang
Pages: 1693-1700
Published online on: 01 June 2010

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Article

BCL2L10 is frequently silenced by promoter hypermethylation in gastric cancer

Rintaro Mikata, Kenichi Fukai, Fumio Imazeki, Makoto Arai, Keiichi Fujiwara, Yutaka Yonemitsu, Kaiyu Zhang, Yoshihiro Nabeya, Takenori Ochiai, Osamu Yokosuka
Pages: 1701-1708
Published online on: 01 June 2010

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Article

HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells

Seiji Adachi, Ichiro Yasuda, Masanori Nakashima, Takahiro Yamauchi, Junichi Yamauchi, Hideo Natsume, Hisataka Moriwaki, Osamu Kozawa
Pages: 1709-1714
Published online on: 01 June 2010

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Article

The cleavage fragment of retinoid X receptor-α ligand binding domain inhibits radiosensitization by retinoic acid

Young-Min Cho, Ae-Hee Yang, Bu-Yeon Kim, Young-Hoon Han
Pages: 1715-1720
Published online on: 01 June 2010

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Article

Differential roles of leptin in regulating cell migration in thyroid cancer cells

Shih-Ping Cheng, Pen-Hui Yin, Yuan-Ching Chang, Chen-Hsen Lee, Shih-Yuan Huang, Chin-Wen Chi
Pages: 1721-1727
Published online on: 01 June 2010

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Article

Kisspeptin is released from human prostate cancer cell lines but plasma kisspeptin is not elevated in patients with prostate cancer

Annette E. Curtis, Kevin G. Murphy, Owais B. Chaudhri, Radha Ramachandran, Anna-Mary Young, Jonathan Waxman, Gurjinder M.K. Nijher, Gavin A. Bewick, Mohammed A. Ghatei, Stephen R. Bloom, Waljit S. Dhillo
Pages: 1729-1734
Published online on: 01 June 2010

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Article

Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines

Hui-Yan Luo, Wei Wei, Yan-Xia Shi, Xiao-Qin Chen, Yu-Hong Li, Feng Wang, Miao-Zhen Qiu, Fang-Hua Li, Shu-Li Yan, Mu-Sheng Zeng, Peng Huang, Rui-Hua Xu
Pages: 1735-1745
Published online on: 01 June 2010

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Article

HERG K+ channel related chemosensitivity to sparfloxacin in colon cancer cells

Jian-Hua Gong, Xiu-Jun Liu, Bo-Yang Shang, Shu-Zhen Chen, Yong-Su Zhen
Pages: 1747-1756
Published online on: 01 June 2010

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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