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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2010 Volume 23 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

HSP90 and its inhibitors (Review)

Huifang Hao, Yoshio Naomoto, Xiaohong Bao, Nobuyuki Watanabe, Kazufumi Sakurama, Kazuhiro Noma, Takayuki Motoki, Yasuko Tomono, Takuya Fukazawa, Yasuhiro Shirakawa, Tomoki Yamatsuji, Junji Matsuoka, Munenori Takaoka
Pages: 1483-1492
Published online on: 01 June 2010

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Article

Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan (Review)

Isao Okazaki, Minoru Sugita, Hideaki Matsuki, Syed Muhammad Baqui Billah, Tetsu Watanabe
Pages: 1493-1500
Published online on: 01 June 2010

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Article Open Access

Comparative transcriptional study of the effects of high intracellular zinc on prostate carcinoma cells

Pooi-Fong Wong, Sazaly Abubakar
Pages: 1501-1516
Published online on: 01 June 2010

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Article Open Access

Anticancer activity of phenoxazines produced by bovine erythrocytes on colon cancer cells

Takeshi Nakachi, Takafumi Tabuchi, Akira Takasaki, Sadao Arai, Keisuke Miyazawa, Akio Tomoda
Pages: 1517-1522
Published online on: 01 June 2010

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Article

Effect of Helicobacter pylori infection on the sonic hedgehog signaling pathway in gastric cancer cells

Jie-Hyun Kim, Yeun Jung Choi, Sang Hun Lee, Hyun Soo Shin, In Ohk Lee, Yu Jin Kim, Hyunki Kim, Woo Ick Yang, Hoguen Kim, Yong Chan Lee
Pages: 1523-1528
Published online on: 01 June 2010

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Article

Potentiation of gemcitabine by Turmeric Force™ in pancreatic cancer cell lines

Cheppail Ramachandran, Anna P. Resek, Enrique Escalon, Anat Aviram, Steven J. Melnick
Pages: 1529-1535
Published online on: 01 June 2010

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Article

Created Gli-1 duplex short-RNA (i-Gli-RNA) eliminates CD44Hi progenitors of taxol-resistant ovarian cancer cells

Takashi Mine, Satoko Matsueda, Hui Gao, Yufeng Li, Kwong-Kwok Wong, George E. Peoples, Soldano Ferrone, Constantin G. Ioannides
Pages: 1537-1543
Published online on: 01 June 2010

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Article

Silibinin reverses epithelial-to-mesenchymal transition in metastatic prostate cancer cells by targeting transcription factors

Kaijie Wu, Jin Zeng, Lei Li, Jinhai Fan, Dong Zhang, Yan Xue, Guodong Zhu, Lin Yang, Xinyang Wang, Dalin He
Pages: 1545-1552
Published online on: 01 June 2010

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Article

IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1

Ronghui Li, Gang Li, Lin Deng, Qinglin Liu, Jun Dai, Jie Shen, Jian Zhang
Pages: 1553-1559
Published online on: 01 June 2010

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Article

Chemokines mediate mesenchymal stem cell migration toward gliomas in vitro

Feng Xu, Jinlong Shi, Bin Yu, Wei Ni, Xing Wu, Zhikai Gu
Pages: 1561-1567
Published online on: 01 June 2010

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Article

Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression

Yamei Ma, Guohua Zhang, Xiangsheng Fu, Oudong Xia, Chunling Zhan, Lianjie Li, Zhiqing Wang, Baoping Wu
Pages: 1569-1576
Published online on: 01 June 2010

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Article

Potential of molecular targeted therapy of HER-2 and Cox-2 for invasive transitional cell carcinoma of the urinary bladder

Katsuya Naruse, Yoshiaki Yamada, Kogenta Nakamura, Shigeyuki Aoki, Tomohiro Taki, Kenji Zennami, Remi Katsuda, Masahito Watanabe, Genya Nishikawa, Youko Itoh, Kenji Mitsui, Hatsuki Hibi, Nobuaki Honda
Pages: 1577-1583
Published online on: 01 June 2010

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Article

Combination therapy with Gamma Knife radiosurgery and antisense EGFR for malignant glioma in vitro and orthotopic xenografts

Yanhe Li, Qiang Jia, Junxia Zhang, Lei Han, Desheng Xu, Anling Zhang, Yipei Zhang, Zhiyuan Zhang, Peiyu Pu, Chunsheng Kang
Pages: 1585-1591
Published online on: 01 June 2010

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Article

PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway

Tao Tian, Ke-Jun Nan, Hui Guo, Wen-Juan Wang, Zhi-Ping Ruan, Shu-Hong Wang, Xuan Liang, Chuang-Xin Lu
Pages: 1593-1600
Published online on: 01 June 2010

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Article

Hepatocytic precursor (stem-like) WB-F344 cells reduce tumorigenicity of hepatoma CBRH-7919 cells via TGF-β/Smad pathway

Wei-Qing Li, Yi-Ming Li, Jia Guo, Yu-Ming Liu, Xiao-Qun Yang, Hui-Juan Ge, Yi Xu, Hui-Min Liu, Jin He, Hong-Yu Yu
Pages: 1601-1607
Published online on: 01 June 2010

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Article

α1,3 Fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24

Wenhua Li, Wen Zhang, Jianming Luo, Ayong Cao, Ying Zhang, Dan Huang, Weiqi Sheng, Sanjun Cai, Jin Li
Pages: 1609-1617
Published online on: 01 June 2010

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Article

Screening and analysis of pathogenic genes during DMBA-induced buccal mucosa carcinogenesis in golden hamsters

Kai Yang, Guodong Zhang, Jie Mei, Dan Chen, Mingjun Wu
Pages: 1619-1624
Published online on: 01 June 2010

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Article

Expression of microRNAs in squamous cell carcinoma of human head and neck and the esophagus: miR-205 and miR-21 are specific markers for HNSCC and ESCC

Sotai Kimura, Seiji Naganuma, Dai Susuki, Yasuo Hirono, Akio Yamaguchi, Shigeharu Fujieda, Kazuo Sano, Hiroshi Itoh
Pages: 1625-1633
Published online on: 01 June 2010

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Article

Triplet schedule of weekly 5-Fluorouracil and alternating irinotecan or oxaliplatin in advanced colorectal cancer: A dose-finding and phase II study

M. F. Morelli, A. Santomaggio, E. Ricevuto, K. Cannita, F. De Galitiis, M. Tudini, G. Bruera, M. Mancini, M. Pelliccione, F. Calista, F. Guglielmi, F. Martella, P. Lanfiuti Baldi, G. Porzio, A. Russo, N. Gebbia, S. Iacobelli, P. Marchetti, C. Ficorella
Pages: 1635-1640
Published online on: 01 June 2010

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Article

Histological features of extratumoral breast lesions as a predictive factor of familial breast cancer

Anita Mangia, Stefania Tommasi, Michele Bruno, Andrea Malfettone, Cosimo D'Amico, Francesco Alfredo Zito, Angelo Paradiso, Giovanni Simone
Pages: 1641-1645
Published online on: 01 June 2010

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Article

The ratio of serum placenta growth factor to soluble vascular endothelial growth factor receptor-1 predicts the prognosis of hepatocellular carcinoma

Sakae Nagaoka, Takafumi Yoshida, Junji Akiyoshi, Jun Akiba, Takao Hisamoto, Yoko Yoshida, Mitsuhiko Abe, Hironori Koga, Takuji Toirimura, Takato Ueno, Michio Sata
Pages: 1647-1654
Published online on: 01 June 2010

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Article

Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: A Portuguese multicentre study

Bruno M. Costa, Cláudia Caeiro, Inês Guimarães, Olga Martinho, Teresa Jaraquemada, Isabel Augusto, Lígia Castro, Lígia Osório, Paulo Linhares, Mrinalini Honavar, Mário Resende, Fátima Braga, Ana Silva, Fernando Pardal, Júlia Amorim, Rui Nabiço, Rui Almeida, Carlos Alegria, Manuel Pires, Célia Pinheiro, Ernesto Carvalho, José M. Lopes, Paulo Costa, Margarida Damasceno, Rui M. Reis
Pages: 1655-1662
Published online on: 01 June 2010

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Article

Conformal radiotherapy of prostate cancer: What is the proper technique for sparing organs-at-risk?

V. Peppa, M. Mazonakis, S. Kachris, C. Varveris, J. Damilakis
Pages: 1663-1668
Published online on: 01 June 2010

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Article

FHL2 suppresses growth and differentiation of the colon cancer cell line HT-29

Thomas Amann, Yvonne Egle, Anja-Katrin Bosserhoff, Claus Hellerbrand
Pages: 1669-1674
Published online on: 01 June 2010

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Article

The role of hLHX6-HMR as a methylation biomarker for early diagnosis of cervical cancer

Samil Jung, Dongjun Jeong, Jinsun Kim, Lisha Yi, Keunhoe Koo, Jaehyouk Lee, Soon-Duck Lee, Jin-Wha Park, Boogi Chang, Chang-Hwan Kim, Chang-Jin Kim, Myeong-Sok Lee
Pages: 1675-1682
Published online on: 01 June 2010

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Article

Identification of pancreatic juice proteins as biomarkers of pancreatic cancer

Jun Gao, Feng Zhu, Shunli Lv, Zhaoshen Li, Zhang Ling, Yanfang Gong, Chen Jie, Lie Ma
Pages: 1683-1692
Published online on: 01 June 2010

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Article

miRNA-regulated expression of oncogenes and tumor suppressor genes in the cisplatin-inhibited growth of K562 cells

Shu-Yang Xie, You-Jie Li, Ping-Yu Wang, Fei Jiao, Shuai Zhang, Wen-Juan Zhang
Pages: 1693-1700
Published online on: 01 June 2010

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Article

BCL2L10 is frequently silenced by promoter hypermethylation in gastric cancer

Rintaro Mikata, Kenichi Fukai, Fumio Imazeki, Makoto Arai, Keiichi Fujiwara, Yutaka Yonemitsu, Kaiyu Zhang, Yoshihiro Nabeya, Takenori Ochiai, Osamu Yokosuka
Pages: 1701-1708
Published online on: 01 June 2010

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Article

HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells

Seiji Adachi, Ichiro Yasuda, Masanori Nakashima, Takahiro Yamauchi, Junichi Yamauchi, Hideo Natsume, Hisataka Moriwaki, Osamu Kozawa
Pages: 1709-1714
Published online on: 01 June 2010

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Article

The cleavage fragment of retinoid X receptor-α ligand binding domain inhibits radiosensitization by retinoic acid

Young-Min Cho, Ae-Hee Yang, Bu-Yeon Kim, Young-Hoon Han
Pages: 1715-1720
Published online on: 01 June 2010

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Article

Differential roles of leptin in regulating cell migration in thyroid cancer cells

Shih-Ping Cheng, Pen-Hui Yin, Yuan-Ching Chang, Chen-Hsen Lee, Shih-Yuan Huang, Chin-Wen Chi
Pages: 1721-1727
Published online on: 01 June 2010

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Article

Kisspeptin is released from human prostate cancer cell lines but plasma kisspeptin is not elevated in patients with prostate cancer

Annette E. Curtis, Kevin G. Murphy, Owais B. Chaudhri, Radha Ramachandran, Anna-Mary Young, Jonathan Waxman, Gurjinder M.K. Nijher, Gavin A. Bewick, Mohammed A. Ghatei, Stephen R. Bloom, Waljit S. Dhillo
Pages: 1729-1734
Published online on: 01 June 2010

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Article

Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines

Hui-Yan Luo, Wei Wei, Yan-Xia Shi, Xiao-Qin Chen, Yu-Hong Li, Feng Wang, Miao-Zhen Qiu, Fang-Hua Li, Shu-Li Yan, Mu-Sheng Zeng, Peng Huang, Rui-Hua Xu
Pages: 1735-1745
Published online on: 01 June 2010

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Article

HERG K+ channel related chemosensitivity to sparfloxacin in colon cancer cells

Jian-Hua Gong, Xiu-Jun Liu, Bo-Yang Shang, Shu-Zhen Chen, Yong-Su Zhen
Pages: 1747-1756
Published online on: 01 June 2010

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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