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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2010 Volume 23 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

HSP90 and its inhibitors (Review)

Huifang Hao, Yoshio Naomoto, Xiaohong Bao, Nobuyuki Watanabe, Kazufumi Sakurama, Kazuhiro Noma, Takayuki Motoki, Yasuko Tomono, Takuya Fukazawa, Yasuhiro Shirakawa, Tomoki Yamatsuji, Junji Matsuoka, Munenori Takaoka
Pages: 1483-1492
Published online on: 01 June 2010

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Article

Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan (Review)

Isao Okazaki, Minoru Sugita, Hideaki Matsuki, Syed Muhammad Baqui Billah, Tetsu Watanabe
Pages: 1493-1500
Published online on: 01 June 2010

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Article Open Access

Comparative transcriptional study of the effects of high intracellular zinc on prostate carcinoma cells

Pooi-Fong Wong, Sazaly Abubakar
Pages: 1501-1516
Published online on: 01 June 2010

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Article Open Access

Anticancer activity of phenoxazines produced by bovine erythrocytes on colon cancer cells

Takeshi Nakachi, Takafumi Tabuchi, Akira Takasaki, Sadao Arai, Keisuke Miyazawa, Akio Tomoda
Pages: 1517-1522
Published online on: 01 June 2010

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Article

Effect of Helicobacter pylori infection on the sonic hedgehog signaling pathway in gastric cancer cells

Jie-Hyun Kim, Yeun Jung Choi, Sang Hun Lee, Hyun Soo Shin, In Ohk Lee, Yu Jin Kim, Hyunki Kim, Woo Ick Yang, Hoguen Kim, Yong Chan Lee
Pages: 1523-1528
Published online on: 01 June 2010

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Article

Potentiation of gemcitabine by Turmeric Force™ in pancreatic cancer cell lines

Cheppail Ramachandran, Anna P. Resek, Enrique Escalon, Anat Aviram, Steven J. Melnick
Pages: 1529-1535
Published online on: 01 June 2010

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Article

Created Gli-1 duplex short-RNA (i-Gli-RNA) eliminates CD44Hi progenitors of taxol-resistant ovarian cancer cells

Takashi Mine, Satoko Matsueda, Hui Gao, Yufeng Li, Kwong-Kwok Wong, George E. Peoples, Soldano Ferrone, Constantin G. Ioannides
Pages: 1537-1543
Published online on: 01 June 2010

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Article

Silibinin reverses epithelial-to-mesenchymal transition in metastatic prostate cancer cells by targeting transcription factors

Kaijie Wu, Jin Zeng, Lei Li, Jinhai Fan, Dong Zhang, Yan Xue, Guodong Zhu, Lin Yang, Xinyang Wang, Dalin He
Pages: 1545-1552
Published online on: 01 June 2010

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Article

IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1

Ronghui Li, Gang Li, Lin Deng, Qinglin Liu, Jun Dai, Jie Shen, Jian Zhang
Pages: 1553-1559
Published online on: 01 June 2010

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Article

Chemokines mediate mesenchymal stem cell migration toward gliomas in vitro

Feng Xu, Jinlong Shi, Bin Yu, Wei Ni, Xing Wu, Zhikai Gu
Pages: 1561-1567
Published online on: 01 June 2010

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Article

Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression

Yamei Ma, Guohua Zhang, Xiangsheng Fu, Oudong Xia, Chunling Zhan, Lianjie Li, Zhiqing Wang, Baoping Wu
Pages: 1569-1576
Published online on: 01 June 2010

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Article

Potential of molecular targeted therapy of HER-2 and Cox-2 for invasive transitional cell carcinoma of the urinary bladder

Katsuya Naruse, Yoshiaki Yamada, Kogenta Nakamura, Shigeyuki Aoki, Tomohiro Taki, Kenji Zennami, Remi Katsuda, Masahito Watanabe, Genya Nishikawa, Youko Itoh, Kenji Mitsui, Hatsuki Hibi, Nobuaki Honda
Pages: 1577-1583
Published online on: 01 June 2010

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Article

Combination therapy with Gamma Knife radiosurgery and antisense EGFR for malignant glioma in vitro and orthotopic xenografts

Yanhe Li, Qiang Jia, Junxia Zhang, Lei Han, Desheng Xu, Anling Zhang, Yipei Zhang, Zhiyuan Zhang, Peiyu Pu, Chunsheng Kang
Pages: 1585-1591
Published online on: 01 June 2010

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Article

PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway

Tao Tian, Ke-Jun Nan, Hui Guo, Wen-Juan Wang, Zhi-Ping Ruan, Shu-Hong Wang, Xuan Liang, Chuang-Xin Lu
Pages: 1593-1600
Published online on: 01 June 2010

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Article

Hepatocytic precursor (stem-like) WB-F344 cells reduce tumorigenicity of hepatoma CBRH-7919 cells via TGF-β/Smad pathway

Wei-Qing Li, Yi-Ming Li, Jia Guo, Yu-Ming Liu, Xiao-Qun Yang, Hui-Juan Ge, Yi Xu, Hui-Min Liu, Jin He, Hong-Yu Yu
Pages: 1601-1607
Published online on: 01 June 2010

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Article

α1,3 Fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24

Wenhua Li, Wen Zhang, Jianming Luo, Ayong Cao, Ying Zhang, Dan Huang, Weiqi Sheng, Sanjun Cai, Jin Li
Pages: 1609-1617
Published online on: 01 June 2010

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Article

Screening and analysis of pathogenic genes during DMBA-induced buccal mucosa carcinogenesis in golden hamsters

Kai Yang, Guodong Zhang, Jie Mei, Dan Chen, Mingjun Wu
Pages: 1619-1624
Published online on: 01 June 2010

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Article

Expression of microRNAs in squamous cell carcinoma of human head and neck and the esophagus: miR-205 and miR-21 are specific markers for HNSCC and ESCC

Sotai Kimura, Seiji Naganuma, Dai Susuki, Yasuo Hirono, Akio Yamaguchi, Shigeharu Fujieda, Kazuo Sano, Hiroshi Itoh
Pages: 1625-1633
Published online on: 01 June 2010

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Article

Triplet schedule of weekly 5-Fluorouracil and alternating irinotecan or oxaliplatin in advanced colorectal cancer: A dose-finding and phase II study

M. F. Morelli, A. Santomaggio, E. Ricevuto, K. Cannita, F. De Galitiis, M. Tudini, G. Bruera, M. Mancini, M. Pelliccione, F. Calista, F. Guglielmi, F. Martella, P. Lanfiuti Baldi, G. Porzio, A. Russo, N. Gebbia, S. Iacobelli, P. Marchetti, C. Ficorella
Pages: 1635-1640
Published online on: 01 June 2010

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Article

Histological features of extratumoral breast lesions as a predictive factor of familial breast cancer

Anita Mangia, Stefania Tommasi, Michele Bruno, Andrea Malfettone, Cosimo D'Amico, Francesco Alfredo Zito, Angelo Paradiso, Giovanni Simone
Pages: 1641-1645
Published online on: 01 June 2010

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Article

The ratio of serum placenta growth factor to soluble vascular endothelial growth factor receptor-1 predicts the prognosis of hepatocellular carcinoma

Sakae Nagaoka, Takafumi Yoshida, Junji Akiyoshi, Jun Akiba, Takao Hisamoto, Yoko Yoshida, Mitsuhiko Abe, Hironori Koga, Takuji Toirimura, Takato Ueno, Michio Sata
Pages: 1647-1654
Published online on: 01 June 2010

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Article

Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: A Portuguese multicentre study

Bruno M. Costa, Cláudia Caeiro, Inês Guimarães, Olga Martinho, Teresa Jaraquemada, Isabel Augusto, Lígia Castro, Lígia Osório, Paulo Linhares, Mrinalini Honavar, Mário Resende, Fátima Braga, Ana Silva, Fernando Pardal, Júlia Amorim, Rui Nabiço, Rui Almeida, Carlos Alegria, Manuel Pires, Célia Pinheiro, Ernesto Carvalho, José M. Lopes, Paulo Costa, Margarida Damasceno, Rui M. Reis
Pages: 1655-1662
Published online on: 01 June 2010

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Article

Conformal radiotherapy of prostate cancer: What is the proper technique for sparing organs-at-risk?

V. Peppa, M. Mazonakis, S. Kachris, C. Varveris, J. Damilakis
Pages: 1663-1668
Published online on: 01 June 2010

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Article

FHL2 suppresses growth and differentiation of the colon cancer cell line HT-29

Thomas Amann, Yvonne Egle, Anja-Katrin Bosserhoff, Claus Hellerbrand
Pages: 1669-1674
Published online on: 01 June 2010

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Article

The role of hLHX6-HMR as a methylation biomarker for early diagnosis of cervical cancer

Samil Jung, Dongjun Jeong, Jinsun Kim, Lisha Yi, Keunhoe Koo, Jaehyouk Lee, Soon-Duck Lee, Jin-Wha Park, Boogi Chang, Chang-Hwan Kim, Chang-Jin Kim, Myeong-Sok Lee
Pages: 1675-1682
Published online on: 01 June 2010

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Article

Identification of pancreatic juice proteins as biomarkers of pancreatic cancer

Jun Gao, Feng Zhu, Shunli Lv, Zhaoshen Li, Zhang Ling, Yanfang Gong, Chen Jie, Lie Ma
Pages: 1683-1692
Published online on: 01 June 2010

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Article

miRNA-regulated expression of oncogenes and tumor suppressor genes in the cisplatin-inhibited growth of K562 cells

Shu-Yang Xie, You-Jie Li, Ping-Yu Wang, Fei Jiao, Shuai Zhang, Wen-Juan Zhang
Pages: 1693-1700
Published online on: 01 June 2010

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Article

BCL2L10 is frequently silenced by promoter hypermethylation in gastric cancer

Rintaro Mikata, Kenichi Fukai, Fumio Imazeki, Makoto Arai, Keiichi Fujiwara, Yutaka Yonemitsu, Kaiyu Zhang, Yoshihiro Nabeya, Takenori Ochiai, Osamu Yokosuka
Pages: 1701-1708
Published online on: 01 June 2010

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Article

HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells

Seiji Adachi, Ichiro Yasuda, Masanori Nakashima, Takahiro Yamauchi, Junichi Yamauchi, Hideo Natsume, Hisataka Moriwaki, Osamu Kozawa
Pages: 1709-1714
Published online on: 01 June 2010

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Article

The cleavage fragment of retinoid X receptor-α ligand binding domain inhibits radiosensitization by retinoic acid

Young-Min Cho, Ae-Hee Yang, Bu-Yeon Kim, Young-Hoon Han
Pages: 1715-1720
Published online on: 01 June 2010

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Article

Differential roles of leptin in regulating cell migration in thyroid cancer cells

Shih-Ping Cheng, Pen-Hui Yin, Yuan-Ching Chang, Chen-Hsen Lee, Shih-Yuan Huang, Chin-Wen Chi
Pages: 1721-1727
Published online on: 01 June 2010

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Article

Kisspeptin is released from human prostate cancer cell lines but plasma kisspeptin is not elevated in patients with prostate cancer

Annette E. Curtis, Kevin G. Murphy, Owais B. Chaudhri, Radha Ramachandran, Anna-Mary Young, Jonathan Waxman, Gurjinder M.K. Nijher, Gavin A. Bewick, Mohammed A. Ghatei, Stephen R. Bloom, Waljit S. Dhillo
Pages: 1729-1734
Published online on: 01 June 2010

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Article

Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines

Hui-Yan Luo, Wei Wei, Yan-Xia Shi, Xiao-Qin Chen, Yu-Hong Li, Feng Wang, Miao-Zhen Qiu, Fang-Hua Li, Shu-Li Yan, Mu-Sheng Zeng, Peng Huang, Rui-Hua Xu
Pages: 1735-1745
Published online on: 01 June 2010

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Article

HERG K+ channel related chemosensitivity to sparfloxacin in colon cancer cells

Jian-Hua Gong, Xiu-Jun Liu, Bo-Yang Shang, Shu-Zhen Chen, Yong-Su Zhen
Pages: 1747-1756
Published online on: 01 June 2010

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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