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Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases

  • Authors:
    • Hiroki Nishikawa
    • Kazunori Yoh
    • Hirayuki Enomoto
    • Takashi Nishimura
    • Shuhei Nishiguchi
    • Hiroko Iijima
  • View Affiliations / Copyright

    Affiliations: Department of Internal Medicine, Division of Gastroenterology and Hepatology, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan, Department of Internal Medicine, Kano General Hospital, Osaka, 531-0041, Japan
    Copyright: © Nishikawa et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 16
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    Published online on: January 20, 2021
       https://doi.org/10.3892/wasj.2021.87
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Abstract

The causal association between sarcopenia and sleep disorders in patients with chronic liver diseases (CLDs) is unclear. The present study aimed to examine the influence of sarcopenia‑related factors [grip strength (GS) and muscle mass] on the progression of sleep disorders in patients with CLD (n=182, 46 cirrhotic cases; median age, 64 years). Sleep quality was evaluated by the Japanese version of Pittsburgh Sleep Quality Index (PSQI‑J). A PSQI‑J score >5 points was defined as a sleep disorder. In all analyzed patients, evaluation using the PSQI‑J questionnaire was performed >2 times during the observation period. The time interval from the date of baseline PSQI‑J and the first confirmed date of the elevation of PSQI‑J score was calculated. The primary endpoint was the elevation of the PSQI‑J score compared to the baseline PSQI‑J score. The decline in GS was diagnosed with a GS of <26 kg for males and <18 kg for females. The loss of muscle mass was diagnosed by a skeletal muscle index (SMI) of <7.0 kg/m2 for males and <5.7 kg/m2 for females on bioelectrical impedance analysis. The median PSQI‑J score was 5. A PSQI‑J score of >5 points at baseline was found in 83 patients (45.6%). In patients with a decline in GS (n=48), the 3‑year cumulative elevation rate of the PSQI‑J score was 82.4%, while in patients with no decline in GS, it was 36.2% (P<0.0001). In patients with a decline in SMI (n=64), the 3‑year cumulative elevation rate of the PSQI‑J score was 60.6%, while in patients with no decline in SMI, it was 43.4% (P=0.1822). On the multivariate analysis of factors associated with the elevation of the PSQI‑J score, only the decline in GS (P=0.0002) was a significant factor. On the whole, the present study demonstrates that a reduced GS rather than the loss of muscle mass is independently associated with an elevated risk for the progression of sleep disorders in patients with CLD.
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1 

Iwasa M, Karino Y, Kawaguchi T, Nakanishi H, Miyaaki H, Shiraki M, Nakajima T, Sawada Y, Yoshiji H, Okita K, et al: Relationship of muscle cramps to quality of life and sleep disturbance in patients with chronic liver diseases: A nationwide study. Liver Int. 38:2309–2316. 2018.PubMed/NCBI View Article : Google Scholar

2 

Ghabril M, Jackson M, Gotur R, Weber R, Orman E, Vuppalanchi R and Chalasani N: Most individuals with advanced cirrhosis have sleep disturbances, which are associated with poor quality of life. Clin Gastroenterol Hepatol. 15:1271–1278.e6. 2017.PubMed/NCBI View Article : Google Scholar

3 

Córdoba J, Cabrera J, Lataif L, Penev P, Zee P and Blei AT: High prevalence of sleep disturbance in cirrhosis. Hepatology. 27:339–345. 1998.PubMed/NCBI View Article : Google Scholar

4 

Montagnese S, Middleton B, Mani AR, Skene DJ and Morgan MY: Sleep and circadian abnormalities in patients with cirrhosis: Features of delayed sleep phase syndrome? Metab Brain Dis. 24:427–439. 2009.PubMed/NCBI View Article : Google Scholar

5 

Tordjman S, Chokron S, Delorme R, Charrier A, Bellissant E, Jaafari N and Fougerou C: Melatonin: Pharmacology, functions and therapeutic benefits. Curr Neuropharmacol. 15:434–443. 2017.PubMed/NCBI View Article : Google Scholar

6 

Shigiyama F, Kumashiro N, Tsuneoka Y, Igarashi H, Yoshikawa F, Kakehi S, Funato H and Hirose T: Mechanisms of sleep deprivation-induced hepatic steatosis and insulin resistance in mice. Am J Physiol Endocrinol Metab. 315:E848–E858. 2018.PubMed/NCBI View Article : Google Scholar

7 

Mollayeva T, Thurairajah P, Burton K, Mollayeva S, Shapiro CM and Colantonio A: The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples: A systematic review and meta-analysis. Sleep Med Rev. 25:52–73. 2016.PubMed/NCBI View Article : Google Scholar

8 

Buysse DJ, Reynolds CF III, Monk TH, Berman SR and Kupfer DJ: The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Res. 28:193–213. 1989.PubMed/NCBI View Article : Google Scholar

9 

Doi Y, Minowa M, Uchiyama M, Okawa M, Kim K, Shibui K and Kamei Y: Psychometric assessment of subjective sleep quality using the Japanese version of the Pittsburgh Sleep Quality Index (PSQI-J) in psychiatric disordered and control subjects. Psychiatry Res. 97:165–172. 2000.PubMed/NCBI View Article : Google Scholar

10 

Li F, Li Y, Duan Y, Hu CAA, Tang Y and Yin Y: Myokines and adipokines: Involvement in the crosstalk between skeletal muscle and adipose tissue. Cytokine Growth Factor Rev. 33:73–82. 2017.PubMed/NCBI View Article : Google Scholar

11 

Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, et al: Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2: Sarcopenia: Revised European consensus on definition and diagnosis. Age Ageing. 48:16–31. 2019.PubMed/NCBI View Article : Google Scholar

12 

Nishikawa H, Shiraki M, Hiramatsu A, Moriya K, Hino K and Nishiguchi S: Japan Society of Hepatology guidelines for sarcopenia in liver disease (1st edition): Recommendation from the working group for creation of sarcopenia assessment criteria. Hepatol Res. 46:951–963. 2016.PubMed/NCBI View Article : Google Scholar

13 

Sinclair M, Gow PJ, Grossmann M and Angus PW: Review article: Sarcopenia in cirrhosis - aetiology, implications and potential therapeutic interventions. Aliment Pharmacol Ther. 43:765–777. 2016.PubMed/NCBI View Article : Google Scholar

14 

Nishikawa H, Enomoto H, Ishii A, Iwata Y, Miyamoto Y, Ishii N, Yuri Y, Hasegawa K, Nakano C, Nishimura T, et al: Elevated serum myostatin level is associated with worse survival in patients with liver cirrhosis. J Cachexia Sarcopenia Muscle. 8:915–925. 2017.PubMed/NCBI View Article : Google Scholar

15 

Dasarathy S: Myostatin and beyond in cirrhosis: All roads lead to sarcopenia. J Cachexia Sarcopenia Muscle. 8:864–869. 2017.PubMed/NCBI View Article : Google Scholar

16 

Hsu CS and Kao JH: Sarcopenia and chronic liver diseases. Expert Rev Gastroenterol Hepatol. 12:1229–1244. 2018.PubMed/NCBI View Article : Google Scholar

17 

Nishikawa H, Enomoto H, Nishiguchi S and Iijima H: Liver cirrhosis and sarcopenia from the viewpoint of dysbiosis. Int J Mol Sci. 21(5254)2020.PubMed/NCBI View Article : Google Scholar

18 

Bunchorntavakul C and Reddy KR: Review article: Malnutrition/sarcopenia and frailty in patients with cirrhosis. Aliment Pharmacol Ther. 51:64–77. 2020.PubMed/NCBI View Article : Google Scholar

19 

Nishikawa H, Enomoto H, Yoh K, Iwata Y, Sakai Y, Kishino K, Ikeda N, Takashima T, Aizawa N, Takata R, et al: Effect of sarcopenia on sleep disturbance in patients with chronic liver diseases. J Clin Med. 8(16)2018.PubMed/NCBI View Article : Google Scholar

20 

Ida S, Kaneko R, Nagata H, Noguchi Y, Araki Y, Nakai M, Ito S, Ishihara Y, Imataka K and Murata K: Association between sarcopenia and sleep disorder in older patients with diabetes. Geriatr Gerontol Int. 19:399–403. 2019.PubMed/NCBI View Article : Google Scholar

21 

Tan X, Titova OE, Lindberg E, Elmståhl S, Lind L, Schiöth HB and Benedict C: Association between self-reported sleep duration and body composition in middle-aged and older adults. J Clin Sleep Med. 15:431–435. 2019.PubMed/NCBI View Article : Google Scholar

22 

Piovezan RD, Abucham J, Dos Santos RV, Mello MT, Tufik S and Poyares D: The impact of sleep on age-related sarcopenia: Possible connections and clinical implications. Ageing Res Rev. 23:210–220. 2015.PubMed/NCBI View Article : Google Scholar

23 

Fukui H, Saito H, Ueno Y, Uto H, Obara K, Sakaida I, Shibuya A, Seike M, Nagoshi S, Segawa M, et al: Evidence-based clinical practice guidelines for liver cirrhosis 2015. J Gastroenterol. 51:629–650. 2016.PubMed/NCBI View Article : Google Scholar

24 

European Association for the Study of the Liver: Electronic address: simpleEasloffice@easloffice.eu; European Association for the Study of the Liver. EASL Recommendations on Treatment of Hepatitis C 2018. J Hepatol. 69:461–511. 2018.PubMed/NCBI View Article : Google Scholar

25 

Kokudo N, Takemura N, Hasegawa K, Takayama T, Kubo S, Shimada M, Nagano H, Hatano E, Izumi N, Kaneko S, et al: Clinical practice guidelines for hepatocellular carcinoma: The Japan Society of Hepatology 2017 (4th JSH-HCC guidelines) 2019 update. Hepatol Res. 49:1109–1113. 2019.PubMed/NCBI View Article : Google Scholar

26 

Drafting Committee for Hepatitis Management Guidelines: the Japan Society of Hepatology. Japan Society of Hepatology Guidelines for the Management of Hepatitis B Virus Infection: 2019 update. Hepatol Res. 50:892–923. 2020.PubMed/NCBI View Article : Google Scholar

27 

Nishikawa H, Enomoto H, Yoh K, Iwata Y, Sakai Y, Kishino K, Ikeda N, Takashima T, Aizawa N, Takata R, et al: Significant Correlation Between Grip Strength and m2bpgi in Patients with Chronic Liver Diseases. J Clin Med. 8(1359)2019.PubMed/NCBI View Article : Google Scholar

28 

Yoh K, Nishikawa H, Enomoto H, Iwata Y, Ikeda N, Aizawa N, Nishimura T, Iijima H and Nishiguchi S: Grip strength: A useful marker for composite hepatic events in patients with chronic liver diseases. Diagnostics (Basel). 10(238)2020.PubMed/NCBI View Article : Google Scholar

29 

Hanai T, Shiraki M, Imai K, Suetsugu A, Takai K, Moriwaki H and Shimizu M: Reduced handgrip strength is predictive of poor survival among patients with liver cirrhosis: A sex-stratified analysis. Hepatol Res. 49:1414–1426. 2019.PubMed/NCBI View Article : Google Scholar

30 

Dattilo M, Antunes HK, Medeiros A, Mônico Neto M, Souza HS, Tufik S and de Mello MT: Sleep and muscle recovery: Endocrinological and molecular basis for a new and promising hypothesis. Med Hypotheses. 77:220–222. 2011.PubMed/NCBI View Article : Google Scholar

31 

Flood A, Chung A, Parker H, Kearns V and O'Sullivan TA: The use of hand grip strength as a predictor of nutrition status in hospital patients. Clin Nutr. 33:106–114. 2014.PubMed/NCBI View Article : Google Scholar

32 

Samanta J, Dhiman RK, Khatri A, Thumburu KK, Grover S, Duseja A and Chawla Y: Correlation between degree and quality of sleep disturbance and the level of neuropsychiatric impairment in patients with liver cirrhosis. Metab Brain Dis. 28:249–259. 2013.PubMed/NCBI View Article : Google Scholar

33 

Manthravadi S, Paleti S and Pandya P: Impact of sustained viral response postcurative therapy of hepatitis C-related hepatocellular carcinoma: A systematic review and meta-analysis. Int J Cancer. 140:1042–1049. 2017.PubMed/NCBI View Article : Google Scholar

34 

Parikh MP, Gupta NM and McCullough AJ: Obstructive sleep apnea and the liver. Clin Liver Dis. 23:363–382. 2019.PubMed/NCBI View Article : Google Scholar

35 

Weaver MD, Vetter C, Rajaratnam SMW, O'Brien CS, Qadri S, Benca RM, Rogers AE, Leary EB, Walsh JK, Czeisler CA, et al: Sleep disorders, depression and anxiety are associated with adverse safety outcomes in healthcare workers: A prospective cohort study. J Sleep Res. 27(e12722)2018.PubMed/NCBI View Article : Google Scholar

36 

Philip P, Taillard J and Micoulaud-Franchi JA: Sleep restriction, sleep hygiene, and driving safety: The importance of situational sleepiness. Sleep Med Clin. 14:407–412. 2019.PubMed/NCBI View Article : Google Scholar

37 

Blanco JR, Barrio I, Ramalle-Gómara E, Beltran MI, Ibarra V, Metola L, Sanz M, Oteo JA, Melús E and Antón L: Gender differences for frailty in HIV-infected patients on stable antiretroviral therapy and with an undetectable viral load. PLoS One. 14(e0215764)2019.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Nishikawa H, Yoh K, Enomoto H, Nishimura T, Nishiguchi S and Iijima H: Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases. World Acad Sci J 3: 16, 2021.
APA
Nishikawa, H., Yoh, K., Enomoto, H., Nishimura, T., Nishiguchi, S., & Iijima, H. (2021). Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases. World Academy of Sciences Journal, 3, 16. https://doi.org/10.3892/wasj.2021.87
MLA
Nishikawa, H., Yoh, K., Enomoto, H., Nishimura, T., Nishiguchi, S., Iijima, H."Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases". World Academy of Sciences Journal 3.2 (2021): 16.
Chicago
Nishikawa, H., Yoh, K., Enomoto, H., Nishimura, T., Nishiguchi, S., Iijima, H."Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases". World Academy of Sciences Journal 3, no. 2 (2021): 16. https://doi.org/10.3892/wasj.2021.87
Copy and paste a formatted citation
x
Spandidos Publications style
Nishikawa H, Yoh K, Enomoto H, Nishimura T, Nishiguchi S and Iijima H: Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases. World Acad Sci J 3: 16, 2021.
APA
Nishikawa, H., Yoh, K., Enomoto, H., Nishimura, T., Nishiguchi, S., & Iijima, H. (2021). Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases. World Academy of Sciences Journal, 3, 16. https://doi.org/10.3892/wasj.2021.87
MLA
Nishikawa, H., Yoh, K., Enomoto, H., Nishimura, T., Nishiguchi, S., Iijima, H."Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases". World Academy of Sciences Journal 3.2 (2021): 16.
Chicago
Nishikawa, H., Yoh, K., Enomoto, H., Nishimura, T., Nishiguchi, S., Iijima, H."Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases". World Academy of Sciences Journal 3, no. 2 (2021): 16. https://doi.org/10.3892/wasj.2021.87
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