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Management of ventilator‑associated pneumonia due to Stenotrophomonas maltophilia infection: A case report and literature review

  • Authors:
    • Edoardo Campanella
    • Andrea Marino
    • Stefano Stracquadanio
    • Roberta Restivo
    • Cristina Micali
    • Giuseppe Nunnari
    • Bruno Cacopardo
    • Manuela Ceccarelli
  • View Affiliations / Copyright

    Affiliations: Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Messina, I‑98124 Messina, Italy, Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, ARNAS Garibaldi Hospital, University of Catania, I‑95123 Catania, Italy, Department of Biomedical and Biotechnological Sciences, University of Catania, I‑95123 Catania, Italy, Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, ARNAS Garibaldi Hospital, University of Catania, I‑95123 Catania, Italy
    Copyright: © Campanella et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 16
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    Published online on: April 5, 2023
       https://doi.org/10.3892/wasj.2023.193
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Abstract

Stenotrophomonas maltophilia (S. maltophilia) is a difficult‑to‑treat bacteria. This glucose non‑fermenting, multidrug‑resistant Gram‑negative bacillus is known to cause a range of infections, such as skin manifestations and bacteraemia, with respiratory tract infections being the most common. Patients in intensive care units are often exposed to a higher risk of acquiring an infection caused by this pathogen. Although distinguishing between S. maltophilia infections and colonization can be challenging, pneumonia caused by S. maltophilia infection is becoming increasingly prevalent. Furthermore, S. maltophilia infections are often coupled with Pseudomonas aeruginosa infections, reinforcing the need to consider this bacterium as a potential cause of ventilator‑associated pneumonia (VAP). The present study describes the case of a 66‑year‑old male who was diagnosed with VAP due to S. maltophilia infection. This condition was effectively treated with trimethoprim/sulfamethoxazole. The case described herein underscores the importance of prompt recognition through heightened clinical suspicion, particularly in patients with VAP who are unresponsive to broad‑spectrum β‑lactam antibiotics. The early identification of S. maltophilia as the root cause of respiratory tract infections can make a significant difference to the outcomes of affected patients.
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Copy and paste a formatted citation
Spandidos Publications style
Campanella E, Marino A, Stracquadanio S, Restivo R, Micali C, Nunnari G, Cacopardo B and Ceccarelli M: Management of ventilator‑associated pneumonia due to <em>Stenotrophomonas maltophilia</em> infection: A case report and literature review. World Acad Sci J 5: 16, 2023.
APA
Campanella, E., Marino, A., Stracquadanio, S., Restivo, R., Micali, C., Nunnari, G. ... Ceccarelli, M. (2023). Management of ventilator‑associated pneumonia due to <em>Stenotrophomonas maltophilia</em> infection: A case report and literature review. World Academy of Sciences Journal, 5, 16. https://doi.org/10.3892/wasj.2023.193
MLA
Campanella, E., Marino, A., Stracquadanio, S., Restivo, R., Micali, C., Nunnari, G., Cacopardo, B., Ceccarelli, M."Management of ventilator‑associated pneumonia due to <em>Stenotrophomonas maltophilia</em> infection: A case report and literature review". World Academy of Sciences Journal 5.2 (2023): 16.
Chicago
Campanella, E., Marino, A., Stracquadanio, S., Restivo, R., Micali, C., Nunnari, G., Cacopardo, B., Ceccarelli, M."Management of ventilator‑associated pneumonia due to <em>Stenotrophomonas maltophilia</em> infection: A case report and literature review". World Academy of Sciences Journal 5, no. 2 (2023): 16. https://doi.org/10.3892/wasj.2023.193
Copy and paste a formatted citation
x
Spandidos Publications style
Campanella E, Marino A, Stracquadanio S, Restivo R, Micali C, Nunnari G, Cacopardo B and Ceccarelli M: Management of ventilator‑associated pneumonia due to <em>Stenotrophomonas maltophilia</em> infection: A case report and literature review. World Acad Sci J 5: 16, 2023.
APA
Campanella, E., Marino, A., Stracquadanio, S., Restivo, R., Micali, C., Nunnari, G. ... Ceccarelli, M. (2023). Management of ventilator‑associated pneumonia due to <em>Stenotrophomonas maltophilia</em> infection: A case report and literature review. World Academy of Sciences Journal, 5, 16. https://doi.org/10.3892/wasj.2023.193
MLA
Campanella, E., Marino, A., Stracquadanio, S., Restivo, R., Micali, C., Nunnari, G., Cacopardo, B., Ceccarelli, M."Management of ventilator‑associated pneumonia due to <em>Stenotrophomonas maltophilia</em> infection: A case report and literature review". World Academy of Sciences Journal 5.2 (2023): 16.
Chicago
Campanella, E., Marino, A., Stracquadanio, S., Restivo, R., Micali, C., Nunnari, G., Cacopardo, B., Ceccarelli, M."Management of ventilator‑associated pneumonia due to <em>Stenotrophomonas maltophilia</em> infection: A case report and literature review". World Academy of Sciences Journal 5, no. 2 (2023): 16. https://doi.org/10.3892/wasj.2023.193
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