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Article Special Issue Open Access

ABO and RhD matching in platelet transfusions: Real‑world data

This article is part of the special Issue: Natural Products & Phytotherapeutics - Preclinical and Human Studies
  • Authors:
    • Serena Valsami
    • Aspasia Argyrou
    • Abraham Pouliakis
    • Maria Gavalaki
    • Georgios Dryllis
    • Elisavet Grouzi
  • View Affiliations / Copyright

    Affiliations: Hematology Laboratory‑Blood Bank, Aretaieion Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece, Blood Transfusion Department, ‘Agioi Anargyroi’ Hospital, 14564 Athens, Greece, 2nd Department of Pathology, National and Kapodistrian University of Athens, ‘Attikon’ University Hospital, 12462 Athens, Greece, Blood Transfusion Department, Laiko General Hospital, 11527 Athens, Greece, Department of Transfusion Service and Clinical Hemostasis, ‘Saint Savvas’ Oncology Hospital of Athens, 11522 Athens, Greece
    Copyright: © Valsami et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 34
    |
    Published online on: November 2, 2023
       https://doi.org/10.3892/wasj.2023.211
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Abstract

ABO and Rhesus D (RhD) matching in platelet transfusions varies widely worldwide, since it does not preclude good clinical responses. However, it has been shown that ABO and RhD matching selection for platelet transfusions raises efficacy and safety concerns. The present study aimed to assess and evaluate ABO and RhD matching in platelet transfusions. The present study was part of a national survey that evaluated the platelet units, and ABO and RhD blood group of patients, along with the number of platelet units produced and transfused from May to June, 2015. A total of 13,250 [12,061 random donor platelets (RDPs) and 1,189 single donor platelets (SDPs)] were evaluated. ABO identical platelets were transfused in 58.99±0.88% RDPs and 45.75±2.87% SDPs. ABO major incompatible platelets (with antigen incompatibility) were transfused in 15.92±0.66% RDPs and 24.05±2.47% SDPs. ABO minor incompatible platelets (with plasma incompatibility) were transfused in 19.70±0.71% and 22.96±2.43% RDPs and SDPs, respectively, while a combination of ABO major and minor incompatible platelets (combination of plasma and antigen incompatibility) in 5.38±0.41% and 7.23±1.51%, RDPs and SDPs respectively. A total of 6.69 and 12.29% of RhD‑positive RDPs and SDPs were transfused in RhD‑negative patients (both P<0.001). On the whole, the analysis of real‑world data indicates variations in platelet ABO and RhD matching. Further studies are required to elucidate the real impact in the management of patients, while the upcoming centralization of blood services may also be a decisive step in this direction.
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Copy and paste a formatted citation
Spandidos Publications style
Valsami S, Argyrou A, Pouliakis A, Gavalaki M, Dryllis G and Grouzi E: ABO and RhD matching in platelet transfusions: Real‑world data. World Acad Sci J 5: 34, 2023.
APA
Valsami, S., Argyrou, A., Pouliakis, A., Gavalaki, M., Dryllis, G., & Grouzi, E. (2023). ABO and RhD matching in platelet transfusions: Real‑world data. World Academy of Sciences Journal, 5, 34. https://doi.org/10.3892/wasj.2023.211
MLA
Valsami, S., Argyrou, A., Pouliakis, A., Gavalaki, M., Dryllis, G., Grouzi, E."ABO and RhD matching in platelet transfusions: Real‑world data". World Academy of Sciences Journal 5.6 (2023): 34.
Chicago
Valsami, S., Argyrou, A., Pouliakis, A., Gavalaki, M., Dryllis, G., Grouzi, E."ABO and RhD matching in platelet transfusions: Real‑world data". World Academy of Sciences Journal 5, no. 6 (2023): 34. https://doi.org/10.3892/wasj.2023.211
Copy and paste a formatted citation
x
Spandidos Publications style
Valsami S, Argyrou A, Pouliakis A, Gavalaki M, Dryllis G and Grouzi E: ABO and RhD matching in platelet transfusions: Real‑world data. World Acad Sci J 5: 34, 2023.
APA
Valsami, S., Argyrou, A., Pouliakis, A., Gavalaki, M., Dryllis, G., & Grouzi, E. (2023). ABO and RhD matching in platelet transfusions: Real‑world data. World Academy of Sciences Journal, 5, 34. https://doi.org/10.3892/wasj.2023.211
MLA
Valsami, S., Argyrou, A., Pouliakis, A., Gavalaki, M., Dryllis, G., Grouzi, E."ABO and RhD matching in platelet transfusions: Real‑world data". World Academy of Sciences Journal 5.6 (2023): 34.
Chicago
Valsami, S., Argyrou, A., Pouliakis, A., Gavalaki, M., Dryllis, G., Grouzi, E."ABO and RhD matching in platelet transfusions: Real‑world data". World Academy of Sciences Journal 5, no. 6 (2023): 34. https://doi.org/10.3892/wasj.2023.211
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