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World Academy of Sciences Journal
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Print ISSN: 2632-2900 Online ISSN: 2632-2919
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May-June 2026 Volume 8 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Review Open Access

Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review)

  • Authors:
    • Tasiu Hassan Aliyu
    • Mohini Singh
    • Richa Mishra
    • Prashant Kumar Tiwari
    • Santosh Kumar Mishra
    • Abdul Munafi Salisu Umar
    • Sanjay Kumar

  • View Affiliations / Copyright

    Affiliations: Biological and Bio‑Computational Laboratory, Department of Life Science, Sharda School of Bioscience and Technology, Sharda University, Greater Noida, Uttar Pradesh 201310, India, Department of Life Science, Sharda School of Bioscience and Technology, Sharda University, Greater Noida, Uttar Pradesh 201310, India, Department of Computer Engineering, Parul University, Vadodara, Gujarat 391760, India
    Copyright: © Aliyu et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 37
    |
    Published online on: March 18, 2026
       https://doi.org/10.3892/wasj.2026.452
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Abstract

Acute myeloid leukemia (AML) is form of cancer that affects the bone marrow and blood and is characterized by the rapid proliferation of abnormal white blood cells that transfer normal cells. Circular RNAs (circRNAs) constitute a set of special RNAs resulting from the involving from the downstream splice donor and upstream splice acceptor. Several studies have verified that circRNAs have various functions in cancer cells, either by promoting or inhibiting tumor progression and harmonizing the biological activities of malignant tumors, as well as cell proliferation, invasion, migration and metastasis. Exosomal circRNAs have emerged as potential biomarkers for a variety of diseases, such as cancer. They play a critical role in cancer metastasis. CircRNAs are stable and resistant to degradation compare to linear RNAs.  They exhibit severak advantages as biomarkers, including abundance, stability and specificity. Exosomal circRNAs plays various roles in cancer cells due to their intercellular communications. The present review mainly focuses on the role of exosomal circRNAs in AML, and their role as biomarkers in diagnosis, prognosis and treatment response. Furthermore, the present review discusses various avenues of exosomal circRNAs for therapeutic intervention, which may lead to the deepened of novel effective management strategies for AML.

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Copy and paste a formatted citation
Spandidos Publications style
Aliyu TH, Singh M, Mishra R, Tiwari PK, Mishra SK, Umar AM and Kumar S: Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review). World Acad Sci J 8: 37, 2026.
APA
Aliyu, T.H., Singh, M., Mishra, R., Tiwari, P.K., Mishra, S.K., Umar, A.M., & Kumar, S. (2026). Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review). World Academy of Sciences Journal, 8, 37. https://doi.org/10.3892/wasj.2026.452
MLA
Aliyu, T. H., Singh, M., Mishra, R., Tiwari, P. K., Mishra, S. K., Umar, A. M., Kumar, S."Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review)". World Academy of Sciences Journal 8.3 (2026): 37.
Chicago
Aliyu, T. H., Singh, M., Mishra, R., Tiwari, P. K., Mishra, S. K., Umar, A. M., Kumar, S."Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review)". World Academy of Sciences Journal 8, no. 3 (2026): 37. https://doi.org/10.3892/wasj.2026.452
Copy and paste a formatted citation
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Spandidos Publications style
Aliyu TH, Singh M, Mishra R, Tiwari PK, Mishra SK, Umar AM and Kumar S: Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review). World Acad Sci J 8: 37, 2026.
APA
Aliyu, T.H., Singh, M., Mishra, R., Tiwari, P.K., Mishra, S.K., Umar, A.M., & Kumar, S. (2026). Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review). World Academy of Sciences Journal, 8, 37. https://doi.org/10.3892/wasj.2026.452
MLA
Aliyu, T. H., Singh, M., Mishra, R., Tiwari, P. K., Mishra, S. K., Umar, A. M., Kumar, S."Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review)". World Academy of Sciences Journal 8.3 (2026): 37.
Chicago
Aliyu, T. H., Singh, M., Mishra, R., Tiwari, P. K., Mishra, S. K., Umar, A. M., Kumar, S."Exosomal circular RNAs in acute myeloid leukemia: Current updates and future prospects (Review)". World Academy of Sciences Journal 8, no. 3 (2026): 37. https://doi.org/10.3892/wasj.2026.452
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